peptide

Proteomelab™ PA 800 Protein Characterization System

...nt and molecular weight, generates high-resolution peptide maps and carbohydrate profiles and provides front-end separation to mass spectrometry....

IGF-1 EIA Endocrine Function 026-AC-27F1 Insulin Growth Factor

...r of biological activities similar to insulin. The peptide is growth hormone (GH) dependent to a high degree, but there is growing evidence of GH-independent secretion. IGF-1 has numerous growth-promoting effects, including mitogenic effects and the promotion of cartilage sulphation. It also mediates growth ...

Angiotensin II RIA Hypertension / Cardiac Evaluation, Cardiovascular 001-RK-A22

...agent known to date and is the biologically active peptide of the renin-angiotensin system (RAS). The proteolytic enzyme renin, synthesized, stored and secreted primarily by the juxtaglomerular cells of the kidneys, cleaves angiotensinogen to produce the decapeptide angiotensin I (Ang I) which is physiologic...

ACE - REA Hypertension / Cardiac Evaluation, Cardiovascular 001-RK-ACD Angiotensin Converting Enzyme

...d to the endothelial surface membrane by an anchor peptide and can be cleaved to be released into the blood circulation as soluble enzyme. Angiotensin converting enzyme (ACE) catalyzes the conversion of angiotensin I to angiotensin II. The enzyme also mediates the cleavage of a synthetic substrate, 3H hippur...

Genetic Systems HIV-1/HIV-2 Peptide EIA

EIA for Donor Screening. Synthetic peptide Enzyme Immunoassay (EIA) for the detection of antibodies to Human Immunodeficiency Virus Types 1 and/or 2(HIV-1 and HIV-2) in human serum, plasma or cadaveric serum specimens....

Triage BNP Test

...t for CHF. Blood test measuring B-type natriuretic peptide (BNP) Cardiac hormone produced by the heart ventricles in response to ventricular volume expansion and pressure overload. Excellent hormonal marker of ventricular systolic and diastolic dysfunction. The Triage BNP Test provides meaningful diagnostic ...

Multispot HIV-1/HIV-2 Rapid Test

...IV-2 is a rapid indirect EIA using recombinant and peptide antigens for simultaneous detection and differentiation of anti-HIV-1 and anti-HIV-2 antibodies in human serum or plasma....

Calcitonin RIA Test

...estinal peptides, estrogens and vitamin D. Gastric peptide stimulation of calcitonin secretion following a meal may play a role in maintaining postprandial calcium homeostasis. Abnormally elevated levels of calcitonin are characteristic of thyroid C-cell hyperplasia and medullary thyroid carcinoma [2,3]. Ele...

Calcitonin, Ultra-Sensitive RIA Test

...estinal peptides, estrogens and vitamin D. Gastric peptide stimulation of calcitonin secretion following a meal may play a role in maintaining postprandial calcium homeostasis. Abnormally elevated levels of calcitonin are characteristic of thyroid C-cell hyperplasia and medullary thyroid carcinoma [2,3]. Ele...

IGF-I

...nsulin-like growth factor I or somatomedin-C, is a peptide highly dependent on growth hormone and has potent growth promoting activity. IGF-I is transported in serum by several IGF-binding proteins. In the diagnosis of growth disorders, measurements of IGF-I are a useful adjunct to assessment of growth hormo...

Free IGF-I ELISA Test

...wth factor I (IGF-I or somatomedin C) is a 7.6 kDa peptide produced primarily in the liver. It acts as a potent mitogen of cellular proliferation, exerting its actions by binding to specific cell-surface receptors. In the circulation, IGF-I is bound to IGF-binding proteins (IGFBPs), which appear to regulate ...

IGF-I ELISA Test (Non-Extraction)

...wth factor I (IGF-I or somatomedin C) is a 7.6 kDa peptide produced primarily in the liver. It acts as a potent mitogen of cellular proliferation, exerting its actions by binding to specific cell-surface receptors. In the circulation, IGF-I is bound to IGF-binding proteins (IGFBPs), which appear to regulate ...

IGF-I IRMA Test (Non-Extraction)

...wth factor I (IGF-I or somatomedin C) is a 7.6 kDa peptide produced primarily in the liver. It acts as a potent mitogen of cellular proliferation, exerting its actions by binding to specific cell-surface receptors. In the circulation, IGF-I is bound to IGF-binding proteins (IGFBPs), which appear to regulate ...

IGF-I ELISA Test (With Extraction)

...wth factor I (IGF-I or somatomedin C) is a 7.6 kDa peptide produced primarily in the liver. It acts as a potent mitogen of cellular proliferation, exerting its actions by binding to specific cell-surface receptors. In the circulation, IGF-I is bound to IGF-binding proteins (IGFBPs), which appear to regulate ...

IGF-I IRMA Test (With Extraction)

...wth factor I (IGF-I or somatomedin C) is a 7.6 kDa peptide produced primarily in the liver. It acts as a potent mitogen of cellular proliferation, exerting its actions by binding to specific cell-surface receptors. In the circulation, IGF-I is bound to IGF-binding proteins (IGFBPs), which appear to regulate ...

Free IGF-I IRMA Test

...wth factor I (IGF-I or somatomedin C) is a 7.6 kDa peptide produced primarily in the liver. It acts as a potent mitogen of cellular proliferation, exerting its actions by binding to specific cell-surface receptors. In the circulation, IGF-I is bound to IGF-binding proteins (IGFBPs), which appear to regulate ...

Calcitonin IRMA Test

...estinal peptides, estrogens and vitamin D. Gastric peptide stimulation of calcitonin secretion following a meal may play a role in maintaining postprandial calcium homeostasis. Abnormally elevated levels of calcitonin are characteristic of thyroid C-cell hyperplasia and medullary thyroid carcinoma [2,3]. Ele...

Leptin Soluble Receptor ELISA Test

Leptin is a 16kDa peptide encoded by the ob gene and is produced exclusively by adipocytes. It is believed to play a key role in the regulation of body weight by influencing energy intake and expenditure [1,2]. Leptin functions as a lipostat and is produced by adipocytes in r...

IGF-II, Non-Extraction ELISA Test

...nsulin-like growth factor II (IGF-II) is a 7.5 kDa peptide which is secreted primarily by the liver and is postulated to have mitogenic and metabolic actions involved in cellular growth. The actions of IGF-II are mediated by binding to target cell receptors. IGF-II binds with high affinity to the Type II IGF...

IGF-II, Non-Extraction IRMA Test

...nsulin-like growth factor II (IGF-II) is a 7.5 kDa peptide which is secreted primarily by the liver and is postulated to have mitogenic and metabolic actions involved in cellular growth. The actions of IGF-II are mediated by binding to target cell receptors. IGF-II binds with high affinity to the Type II IGF...

IGF-II, w/ Extraction ELISA Test

...nsulin-like growth factor II (IGF-II) is a 7.5 kDa peptide which is secreted primarily by the liver and is postulated to have mitogenic and metabolic actions involved in cellular growth. The actions of IGF-II are mediated by binding to target cell receptors. IGF-II binds with high affinity to the Type II IGF...

IGF-II, w/ Extraction IRMA Test

...nsulin-like growth factor II (IGF-II) is a 7.5 kDa peptide which is secreted primarily by the liver and is postulated to have mitogenic and metabolic actions involved in cellular growth. The actions of IGF-II are mediated by binding to target cell receptors. IGF-II binds with high affinity to the Type II IGF...

PYY, Total ELISA Test

..., the N-terminal truncated form of the full length peptide (3). In common with leptin, this peptide has been shown to cross the blood-brain-barrier and act on the arcuate nucleus of the hypothalamus, ...

Ghrelin, Total ELISA Test

Ghrelin is a 28 amino-acid lipophilic peptide with a labile octanoic acid side chain at the serine residue three, that is primarily expressed in specialized enterochromaffin cells located mainly in the mucosa of the fundus of the stomach (1) and has metabolic effects opposite to those of leptin....

ALS, Total ELISA Test

...which is produced in the liver as a 578 amino acid peptide with a predicted molecular weight of 63.3 kDa. IGFs in human serum are mostly confined to a ~150 KDa GH-dependent ternary protein complex consisting of IGFBP-3, a molecule of IGF-I or IGF-II, and this unique acid-labile subunit (ALS) [1-6]. The firs...

C6 B. burgdorferi (Lyme) ELISA Kit

This ELISA is based on the C6 peptide antigen, a 26 amino acid sequence of the surface protein VlsE. This peptide has been shown to represent the immunodominant portion of VlsE, containing substantially all of the ...

DIASTAT™ Anti-CCP

...of autoantibodies against the cyclic citrullinated peptide (CCP) containing modified arginine residues in human serum or plasma. Enabling early and accurate diagnosis of RA, the Anti-CCP assay provides an additional tool in the diagnosis and management of patients with RA....