glycoprotein

ACE - REA Hypertension / Cardiac Evaluation, Cardiovascular 001-RK-ACD Angiotensin Converting Enzyme

... weight of at least 129,000. The structure of this glycoprotein shows a single polypeptide chain, a polysaccharide residue and a zinc atom. ACE is present in many different cell types such as neuronal cells and renal proximal tubular cells, but is mostly found in endothelial cells. It is attached to the endotheli...

LH IRMA Test

Luteinizing hormone (LH) is a glycoprotein secreted by the anterior pituitary gland. Like the FSH, hCG and TSH, the intact LH molecule is a noncovalently-linked dimer containing alpha- and beta-subunits. These glycoproteins all have homologous alpha-subunits, however each hormone has a unique...

LH ELISA Test

Luteinizing hormone (LH) is a glycoprotein secreted by the anterior pituitary gland. Like the FSH, hCG and TSH, the intact LH molecule is a noncovalently-linked dimer containing alpha- and beta-subunits. These glycoproteins all have homologous alpha-subunits, however each hormone has a unique...

HSV Typing ASR

...ains primers and a FAM-labeled probe targeting the glycoprotein D gene of HSV Type 1 as well as primers and an Alexa 532-labeled probe designed to detect the glycoprotein G gene of HSV Type 2. This ASR requires an instrument that can detect FAM, Texas Red, and Alexa repo...

FSH IRMA Test

Follicle-stimulating hormone (FSH) is a glycoprotein hormone secreted by the anterior pituitary gland. Like hCG, LH and TSH, the intact FSH molecule is a noncovalently-linked dimer consisting of alpha- and beta-subunits. Its production and secretion are stimulated by gonadotropin-releasing hormone (GnR...

FSH ELISA Test

Follicle-stimulating hormone (FSH) is a glycoprotein hormone secreted by the anterior pituitary gland. Like hCG, LH and TSH, the intact FSH molecule is a noncovalently-linked dimer consisting of alpha- and beta-subunits. Its production and secretion are stimulated by gonadotropin-releasing hormone (GnR...

InSite™ Her-2/neu Kit

The Her-2/neu protein is a 185 kD trans-membrane glycoprotein associated with tyrosine kinase activity. Approximately 20-30% cases of breast cancer show an amplification and/or over-expression of Her-2/neu in tumor cells. Since the introduction of Herceptin® as a targeted therapy for breast cancer, the clin...

TSH IRMA Test

Thyroid-stimulating hormone (TSH) is a 32 kDa glycoprotein secreted by the thyrotrope cells of the anterior pituitary gland [1]. The structure of human TSH is similar to that of the pituitary and placental gonadotropins, consisting of an a-subunit which is similar or identical between these hormones and a un...

TSH ELISA Test

Thyroid-stimulating hormone (TSH) is a 32 kDa glycoprotein secreted by the thyrotrope cells of the anterior pituitary gland [1]. The structure of human TSH is similar to that of the pituitary and placental gonadotropins, consisting of an a-subunit which is similar or identical between these hormones and a un...

Intact hCG ELISA Test

...in (hCG) is a two chain (alpha- and beta-subunits) glycoprotein hormone secreted by the chorionic tissue of the placenta and is normally found in urine and blood during pregnancy. Produced by the trophoblastic epithelium of the placenta, hCG acts to maintain the corpus luteum in the early stages of pregnancy. The...

Intact hCG IRMA Test

...in (hCG) is a two chain (alpha- and beta-subunits) glycoprotein hormone secreted by the chorionic tissue of the placenta and is normally found in urine and blood during pregnancy. Produced by the trophoblastic epithelium of the placenta, hCG acts to maintain the corpus luteum in the early stages of pregnancy. The...

MIS/AMH ELISA Test

...as Anti-Mullerian Inhibiting Substance (AMH), is a glycoprotein dimer composed of two 72 kDa monomers linked by disulfide bridges (1). MIS/AMH belongs to the transforming growth factor-? (TGF-?) superfamily which includes TGF-? and the various inhibin and activin glycoproteins (2). All members of this superfamily...

PAPP-A ELISA Test

...sma protein A (PAPP-A) is a large placenta-derived glycoprotein [1]. PAPP-A is produced in high concentrations by placental trophoblast cells, and is released into the maternal circulation in increasing concentrations throughout gestation until delivery [1]. PAPP-A is not specific to pregnancy since measurable le...

PAPP-A, Ultra-Sensitive ELISA Test

...sma protein A (PAPP-A) is a large placenta-derived glycoprotein [1]. PAPP-A is produced in high concentrations by placental trophoblast cells, and is released into the maternal circulation in increasing concentrations throughout gestation until delivery [1]. PAPP-A is not specific to pregnancy since measurable le...

SHBG IRMA Test

...man sex hormone-binding globulin (SHBG) is a serum glycoprotein which binds several sex steroids with relatively high specificity and low capacity, including testosterone and dihydrotestosterone (combined 95% bound to SHBG) and, to a much lesser extent, estradiol [1]. SHBG specifically binds C18 and C19 steroid s...