Canary Foundation and Stanford University Commit $20 Million for World-Class Research Center for Cancer Early Detection
... in the world to integrate research on both in vivo
and in vitro diagnostics to deliver blood and ... facility that combines in vitro and in vivo
strategies to enhance future cancer detection and ... and will include new faculty hires in both ex vivo
VisEn Medical Launches Expanded FMT 2500(TM) Imaging Platforms at AACR Meeting
... Ranges and Multiplexing of Disease Biomarkers In vivo
VisEn Multi-Modality Imaging Adapter Series ... VisEn Medical Inc., a leader in fluorescence in vivo
imaging from research through medicine, ... range of multi-modality and multi-plexing in vivo
imaging products will allow FMT 2500-equipped ...
Mersana's Second Development Candidate, XMT-1107, Shows Superior Pharmacokinetics and Anti-Tumor Activity in Studies Presented at American Association of Cancer Research Meeting
... fumagillin-derived polymer conjugate, and its in vivo
release product XMT-1191"
By Laura C. ... assays, and showed anti-angiogenesis activity in vivo
in the Matrigel plug assay. Additionally, ... tumor models. The enhanced antiangiogenic and in vivo
anti-tumor activity of XMT-1107 compared to its ...
JCI online early table of contents: April 13, 2009
... and small, which makes them ideal for in vivo
imaging studies. In the study, the researchers ... TITLE: A zebrafish model of tauopathy allows in vivo
imaging of neuronal cell death and drug ... however, the method of lipoprotein uptake in vivo
remains poorly defined. In a new study, Howard S. ...
NeurogesX Reports Fourth Quarter and Year-End 2008 Results
... prodrugs of acetaminophen, have completed in vivo
and in vitro preclinical studies, in which ... protectant, has been evaluated in vitro and in vivo
. Equivalent dose levels of NGX-1576 in mice ... has been evaluated in proof of concept in vivo
and in vitro preclinical studies for its ...
University of Notre Dame Chooses Latest Technology From Carestream Molecular Imaging For Disease Research
... University of Notre Dame is using the latest in vivo
and in vitro optical molecular imaging technology ... University of Notre Dame is using the latest in vivo
and in vitro optical molecular imaging technology ... and other medical applications.
The In vivo
Imaging Core, part of the recently commissioned ...
SuperGen Reports 2008 Fourth Quarter and Year-End Financial Results
... clinical trial.
Abstract 332: In vivo
activity of SGI-1776, an orally active PIM kinase ... of JAK2 signaling pathways in vitro and in vivo
by SGI-1252, a small molecule JAK2 inhibitor.
... SGI-1776, is active both in vitro and in vivo
in preclinical models of acute lymphoblastic ...
Cell microenvironments hold key to future stem cell therapies
... human adult stem cell niches cannot be done in vivo
and that scientists can only learn so much from ... must be done under as close as possible to in vivo
"Our technology mimics actual in vivo
conditions and enables us to perform highly ...
Michael J. Fox Foundation Awards $1.9 Million for Development of Non-Invasive Neuroimaging Techniques in Living Brain
... and Screening of Contrast Agents for In vivo
Imaging of PD
Brian Bacskai, PhD, and Pamela ... Conformation-specific Aptamers for In vivo
Bioimaging of Alpha-Synuclein Pathology
Poul ... PhD, United Arab Emirates University
SPECT Imaging of Synuclein Aggregation with ...
CRi to Distribute VisEn Medical's Portfolio of Fluorescence In Vivo Imaging Agents and Labels in North America
... and extend today's leading fluorescence in vivo
imaging technologies, applications and standards ... deep heritage in multi-spectral fluorescence in vivo
imaging and fluorescence microscopy imaging ... research today. Bringing VisEn's fluorescent in vivo
agents and labels to our Maestro(TM) ...
ViroPharma Provides Update on Vancocin(R)
... to inactive ingredients, FDA is recommending in vivo
BE studies with clinical endpoints in patients ... the described in vitro tests to an in vivo
outcome, as required by FDA's regulation. A ... in vitro lab-based tests are correlated with in vivo
outcomes to avoid any potential danger to ...
Cellular senescence a double-edged sword
... suppressor has been well characterized through in vivo
studies, but the details of cellular senescence ... process was first reported in cultures that an in vivo
assay developed by Campisi and an earlier team of ... it occurs not only in cultured cells, but also in vivo
in response to DNA damage.
"We showed that ...
VisEn Co-Founder Named Radiologic Society's 'Outstanding Researcher of the Year'
... as well as a portfolio of fluorescence in vivo
imaging agents. The VisEn FMT 2500(TM) ... 3D quantification of disease biologies in vivo
and is used by leading research institutions and ... and markets a broad range of fluorescent in vivo
imaging agents enabling the quantification and ...
New Study Data: JANUVIA™ (sitagliptin) Significantly Reduced Blood Sugar Levels and Was Not Associated with Hypoglycemia in Elderly Patients with Type 2 Diabetes
... protein binding displacement is very low.
Assessment of Drug Interactions
Effects of ... warfarin, or oral contraceptives, providing in vivo
evidence of a low propensity for causing drug ... hepatocyte DNA alkaline elution assay, and an in vivo
rat fertility studies ...
VisEn Medical Raises $5.0 Million in Expanded Series B Financing
... VisEn Medical, Inc., a leader
in fluorescence in vivo
imaging, today announced the expansion of ... further
advance its proprietary fluorescence in vivo
imaging product pipelines, and
to expand its ... "VisEn is a market leader in fluorescence in vivo
pre-clinically, and well positioned to ...
VisEn Medical Launches FMT(TM) 2500 - Next-Generation Fluorescence Imaging System
... -New Instrument Generates Real-Time In vivo
Data via Quantitative ... VisEn Medical, Inc., a leader
in fluorescence in vivo
imaging, today announced the commercial launch ... the industry's highest performing
fluorescence in vivo
imaging technology platforms, from research ...
DyCE(TM) (Dynamic Contrast Enhancement) Technology Now Part of CRi's Analysis Software Suite for the Popular Maestro(TM) in vivo Molecular Imaging System
... to users of the award-winning
Maestro(TM) in vivo
molecular imaging system. Customers can now ... Molecular Imaging joint conference for in vivo
imaging. DyCE was also
featured in the cover ... for optical imaging, poised to
revolutionize in vivo
fluorescence imaging," says James Mansfield, ...
Sigma-Aldrich Licenses From NeuroSurvival Technologies a Leading Marker for Molecular Imaging of Apoptosis in Vivo
... molecular imaging of apoptosis in vitro and in vivo
in animals. The
marker, developed by NST, will be ... is in clinical trials for imaging
apoptosis in vivo
in humans with PET (positron emitting tomography) ... thus enabling easy and accurate detection in vivo
of this important
cell death process. Thus, by ...
Caliper Life Sciences Reports Fourth Quarter and Full Year 2007 Results
... the second quarter of 2007, plus expanded in vivo
phenotyping business with pharmaceutical ... desktop liquid handler, and CDAS in
vitro and in vivo
services. This evidence of market support ... to bridge
the gap between in vitro assays and in vivo
results and then translating
those results into ...
Antidepressants that are more efficient and faster
... Estudio mediante microdilisis cerebral in vivo
(New strategies of antidepressive boosting based ... and serotonergic systems. A study using in vivo
cerebral microdialysis) was directed by Professor ... study involved animals using the technique of in vivo
cerebral microdialysis; that is, using surgery we ...
Experimental Biology 2008 Today's Research: Tomorrow's Health, April 5-9
... including demonstration of a new method of in vivo
imaging of the cell motions and interactions that build embryos and discussion of vivo
imaging to trace cell lineage. Three dimensional ... illustration--the earliest method of in vivo
imaging--is followed by an exhibit on anatomical ...
Caliper Life Sciences Ships 500th IVIS Imaging System
... IVIS system illustrates the growing demand for in vivo
speed the drug discovery and ... arena to create a bridge between in vitro and in vivo
and help researchers predict outcomes in ... to bridge
the gap between in vitro assays and in vivo
results and then translating
those results into ...
JCI table of contents: Nov. 8, 2007
... SHGB in vitro by a human liver cell line and in vivo
by the liver of mice engineered to express human ... understood. A new tool to determine the in vivo
function of GPCRs in mice has now been generated ... Probing cell typespecific functions of Gi in vivo
identifies GPCR regulators of insulin secretion ...
Sagent Pharmaceuticals Inc. Completes $53 Million Series A Financing
... of a $53 million Series A financing led by vivo
from the financing will be ... and distribution partnerships. "We appreciate vivo
Ventures' continued commitment to ... visit
http://www.sagentpharma.com . About vivo
ViroPharma Announces Support by Advisory Committee of The Office of Generic Drugs Proposed Guidelines for Developing Generic Versions of Oral Vancomycin Hydorchloride
... to use less rigorous standards, including in vitro rather than in vivo
testing, for establishing BE rather than using comparative clinical ... ViroPharma, the proposed in vitro test conditions do not mimic the in vivo
environment of the CDI patient and the qualitative and quantitative ...
Growth in Personalized Medicine to Drive Alliances Between Diagnostics and Pharmaceutical Industries, According to PricewaterhouseCoopers
... tests outside the body, for example in a test tube. By contrast, in vivo
diagnostics perform tests inside the living body, as for example in medical imaging. In vivo
diagnostics industries are not reviewed in this report.
American Orthopaedic Society for Sports Medicine (AOSSM) Presents Prestigious Research Awards at Annual Meeting
... reconstruction of an isolated posterior cruciate ligament injury: In vivo
analysis during physiologic loading." The paper was voted the best overall research paper based on clinical research or human in vivo
research. The authors explored how abnormal movement of the shin bone and ...
Fate Therapeutics Granted Exclusive License By The Regents of the University of California to Stem Cell Modulators for Osteo-Regeneration
... Ph.D., professor of chemistry and biochemistry, and have been shown in vivo
to exhibit osteo-regenerative activity. While many current medications ... of these novel small molecules has been confirmed in several different in vivo
proof of concept studies, and we look forward to their continued ...
Scientists Gather to Discuss Novel Uses of Caliper Life Sciences' Discovery Platforms and Technology
... to discuss the importance of Caliper's automation, microfluidics, and in vivo
imaging technologies. Key themes included approaches for obtaining higher ... innovating new technology to bridge the gap between in vitro assays and in vivo
results and then translating those results into cures for human disease. ...
AlphaRx and Gaia BioPharma Report Positive Efficacy Results in a Pre-Clinical Trial of GAI-122 Injectable Nano-emulsion for Post-operative Delirium
... providing significant
neuro-protection in multiple in vitro and in vivo
studies which suggest
that this injectable nanoemulsion formulation ... results on GAI-122 injectable nanoemulsion in multiple in vitro and in vivo
studies of memory impairment after prolonged anesthesia.
Delirium is a ...
Adenoviral vector specifically targeted to EphA2 receptor in pancreatic cancer cells
... cancer cell lines. Upon demonstrating specific in vitro targeting, in vivo
targeting to subcutaneous growing human pancreatic cancer was tested by ... cancer cells was enhanced almost 10-fold in vitro. In
a subsequent in vivo
study of a nude (nu/nu ) mouse model however, no increased adenoviral ...
First evidence for DNA-based vaccination against chronic hepatitis C
... trial of a therapeutic vaccination using naked DNA delivered by in vivo
electroporation (EP), antiviral effects were shown in patients with ... the cytomegalovirus immediate-early promoter (ChronVac-C) delivered by in vivo
electroporation (EP). A first phase I/IIa clinical trial in HCV infected ...
Dieter Luetticken Award 2008 Recognizes Development of New Vaccine Quality Control Assay
... vaccines. Previously, quality control of NDV vaccines included an in vivo
potency assay in chickens. The new method allows avoiding the use of ... in vitro potency test is an attractive alternative for the existing in vivo
potency tests especially with regard to the objective of the European ...
Breakthrough model for human cancer may improve development of cancer drugs; study in PNAS
... The HIM model is an exciting, experimentally tractable human in vivo
system that holds great potential for advancing our basic understanding of ... system and a gene transduction system, researchers assessed the in vivo
biological consequences of specific genetic alterations in the ...
A new light on tumor immunotherapy for gastric cancer
... Finally, CTL activity and interferon-gamma secretion was evaluated ex vivo
They found that c-kit+ hematopoietic progenitor cells from mice bone ... DCs phenotypic markers and could not stimulate allogeneic T cells. Ex vivo
primed T cells with SGC-7901 tumor cell lysate-pulsed (TP) DCs were able ...
Fate and effects of the drug Tamiflu in the environment
... and will combine studies on the environmental fate of the drug with in vivo
studies of the development of Tamiflu resistant viruses say the project ... been scheduled. Detected environmental levels will then be used in an in vivo
Mallard infection model for detailed studies on the development of Tamiflu ...
Sigma-Aldrich Enters Distribution Agreement With AlphaGenix, Inc.
... a number of enhanced
3-D cell culture systems that better resemble in vivo
systems. Both MaxGel
and HydroMatrix promote cell growth and migration and ... offer our customers
new tools to grow stem cells that resemble their in vivo
the high-quality antibodies needed to study them."
SinoFresh(R) Nasal Spray Kills MRSA 'Super-Bug' in Live Noses
... Board: SFSH) announced preliminary results today from a
successful in vivo
pilot study indicating that its patented SinoFresh(R)
nasal spray was ... results have exceeded our expectations. The positive
results of this in vivo
study gives us the solid scientific platform we
have needed in order to ...
InNexus Biotechnology Announces Third Antibody and Expands Pipeline of Anticancer Compounds
... of antibodies to CD20 and increases
potency using both in vitro and in vivo
studies. Preliminary data for
DXLr120 already reveals properties akin to ... underway to subject DXLr120 to the full battery of tests for potency,
efficacy and safety used for DXL625.
The company will present at IBC's ...
SpectraGenics Announces $30M in New Funding, Changes Company Name to TRIA Beauty
... financing led by prominent consumer health
care investors. New investors vivo
Ventures and Aisling Capital, along with
existing investors, provided $30 ... a physician's office,"
said Albert Cha, M.D. Ph.D., Managing Partner, vivo
Ventures. "In our
opinion, it's the next frontier in skincare."