Tumors in Medical News

Cost-effectiveness of cetuximab in metastatic colorectal cancer

... only in colorectal cancer patients whose tumors have a wild-type KRAS gene, according to a study ... Cancer Institute . Earlier, patients whose tumors harbored wild-type KRAS were found to have a ... all patients in the study and for patients whose tumors had wild-type KRAS. For all patients, ...

Periodic Dieting May Cut Breast Cancer Risk

... calorie restriction led to dramatic decrease in tumors TUESDAY, Aug. 4 (HealthDay News) -- ... sets of mice predisposed to developing breast tumors were put on different diets: unlimited eating, ... best, with only 9 percent developing mammary tumors compared to 35 percent of those chronically ...

Researchers effectively treat tumors with use of nanotubes

... By injecting man-made, microscopic tubes into tumors and heating them with a quick, 30-second zap of a ... have discovered a way to effectively kill kidney tumors in nearly 80 percent of mice. Researchers say ... Using a mouse model, researchers injected kidney tumors with different quantities of MWCNTs and exposed ...

Brain Scan May Help Predict Cancer Drug Response

... Identifying tumors treatable with Avastin has multiple benefits, ... by U.S. researchers. Avastin, which shrinks tumors by cutting off their blood supply, was approved ... that there was greater water movement in the tumors of people who later had the best response to ...

Nanoparticle-delivered 'Suicide' Genes Slowed Ovarian Tumor Growth

... cancer cells reduced the burden of ovarian tumors in mice, and researchers expect this therapy ... after treatment. They found that while treated tumors increased 2-fold, this was significantly less ... mice. Furthermore, four of the treated tumors failed to grow at all, while all ...

Molecule plays early role in nonsmoking lung cancer

... never-smokers and smokers, including those with tumors resistant to targeted drugs such as gefitinib. The study examined lung tumors from people who had never smoked and found high ... called miR-21. The levels were even higher in tumors that had mutations in a gene called EGFR, a ...

Brookhaven Lab and Hybridyne Imaging Technologies Inc., win R&D 100 award

... methods have limitations. Benign and cancerous tumors cannot easily be distinguished by ultrasound, and fibrous tissues can be mistakenly identified as tumors if patients have had radiation treatment of the ... use as a probe to guide the removal of cancerous tumors while minimizing damage to surrounding healthy ...

Study provides documentation that tumor 'stem-like cells' exist in benign tumors

... isolated stem-like cells in benign (pituitary) tumors and used these "mother" cells to generate new tumors in laboratory mice. Targeting the cells of origin ... makeup and characteristics as the original tumors and were capable of generating new tumors, ...

New strategy in tumor treatment

... Medical School and Amtek, Hanover, NH may treat tumors that do not respond to conventional treatment. ... a combination of two agents to selectively kill tumors while protecting healthy cells. In previous ... greatly increased doses might be used and tumors not susceptible to low doses could be attacked ...

Amgen Announces KRAS Safety Update to U.S. Prescribing Information for Vectibix(R) (Panitumumab)

... treatment benefit for Vectibix in patients whose tumors had KRAS mutations in codon 12 or 13. Use of ... that showed mCRC patients with mutated KRAS tumors do not respond to monotherapy with an ... treatment option for patients with mutated KRAS tumors and redirect those patients to alternative ...

Increase in Thyroid Cancer Puzzles Experts

... are to blame. A new study finds that thyroid tumors of all sizes are being picked up, not just the ... The most pronounced increase was seen in primary tumors under 1.0 centimeters -- small ones for which ... take a wait-and-see approach. The rate for these tumors rose almost 10 percent per year in men (1997 to ...

Peregrine Pharmaceuticals Reports Financial Results for Fiscal Year 2009

... that Cotara specifically localizes to brain tumors at high concentrations with minimal radiation ... that Cotara specifically localizes to brain tumors at high concentrations with minimal radiation ... showed that the concentration of Cotara in brain tumors was on average more than 300-fold higher than in ...

News from Cancer

... performed better for distinguishing benign tumors (91.3% versus 74.4% specificity), adding symptom ... as it improved the ability to distinguish benign tumors (specificity = 97.9%). The authors say the data ... The highest rate of increase was for primary tumors smaller than 1.0 cm, which rose nearly 10 percent ...

Abbott and Oasmia Pharmaceutical Announce Exclusive Distribution Agreement for Paccal(R) Vet, a New Chemotherapeutic Agent for Dogs

... to treat Grade II and Grade III canine mast cell tumors where curative surgery cannot be performed. ... for treating Grade II and Grade III mast cell tumors - both of which can be life-threatening in dogs." ... death in dogs over two years of age. Mast cell tumors are among the most common ...

JNCI news brief: Breast cancer hormone receptor status and risk of a second primary tumor

... Women with hormone receptor (HR) negative first tumors have twice as much risk for developing a second ... They also found that women whose first tumors were hormone-receptor negative, compared with those whose tumors were hormone-receptor positive, had almost twice ...

Anti-angiogenesis treatment improves hearing in some NF2 patients

... treatment successfully shrank characteristic tumors in a small group of NF2 patients, the first ... a drug can shrink vestibular schwannomas benign tumors on the balance and hearing nerves and the first ... is an inherited genetic disorder in which benign tumors develop throughout the nervous system. ...

Drug Shows Promise in Nervous-System Tumor Treatment

... report the first successful drug treatment of tumors in patients with neurofibromatosis type 2 (NF2). In people with NF2, benign tumors develop throughout the nervous system. The most ... and the risk of death. Currently, these tumors are treated with surgery or radiation. This study ...

Cell Pathway May Be Key to Lung Cancer's Spread

... six pathways tested that was hyperactive in lung tumors that went on to metastasize. The pathway was normal in tumors that did not spread. They also observed that WNT/TCF hyperactivity was associated with aggressive tumors and poor survival rates. ...

Study shows PET can measure effectiveness of novel breast cancer treatment

... of the HER2 expression levels in breast cancer tumors is absolutely essential to know whether treatment ... also in some ovarian, prostate and lung cancers. tumors that have an overabundance of HER2 protein are more aggressive and more likely to recur than tumors that do not overexpress the protein. The ...

Study identifies biomarker that safely monitors tumor response to new brain cancer treatment

... ongoing immune response against malignant brain tumors cells. The Cedars-Sinai team led by Pedro R. ... shrunk and completely eliminated very large brain tumors in animals and have trained their immune systems to develop memory so that recurrent tumors are also destroyed," said Castro, principal ...

Cancer Researchers Link DICER1 Gene Mutation to Rare Childhood Cancer

... to develop. When the research team looked at PPB tumors to see if there is any DICER1 protein being made ... Conceivably, the mutated cells do not turn into tumors themselves. Instead, these cells influence ... in early stages and progresses to solid lung tumors over time. If detected in the earliest stages, 90 ...

Misonix Announces Participation in 2nd International Workshop on Focal Therapy

... which in Europe is used for the ablation of tumors and worldwide for other acute health conditions, ... invasive techniques to ablate urological tumors while maximizing organ preservation. High ... America and Asia for trans-rectal ablation of tumors of the prostate gland. Characteristics of HIFU, ...

U-M study finds voice box can be preserved, even with the largest cancers

... ANN ARBOR, Mich. Some patients with large tumors on their larynx can preserve their speech by ... have excluded these patients because their tumors are so large. We found that if a patient's tumor ... tumors, called T4. In addition to being large, T4 tumors have often invaded the nearby cartilage, making ...

The AGA Foundation awards grant to Dr. Michael Choi to further his research on carcinoid tumors

... of the biology behind both neuroendocrine tumors and the corresponding neuroendocrine cells. Carcinoid tumors are rare, slow-growing cancers that usually start ... the biology of carcinoid and neuroendocrine tumors and/or the development of novel therapeutic ...

New Cancer Drug Fights Tumors in Those With BRCA Mutations

... people with the BRCA mutations the drug shrunk tumors in breast, ovarian and prostate cancer. ... In addition, "PARP inhibitors may be used for tumors that Herceptin or tamoxifen are totally incapable ... In this trial, 41 percent of patients saw their tumors disappear. There was a slightly lower response ...

Study pinpoints novel cancer gene and biomarker

... made from GOLPH3 may serve as a biomarker for tumors that can be effectively treated with the chemotherapy drug rapamycin: tumors with a high level of the protein are more apt to ... the cancer cells grew much faster, but the tumors were much more responsive to rapamycin," Chin ...

Peregrine Pharmaceuticals Awarded Broad New U.S. Patent for Vascular Imaging Applications of Its PS-Targeting Platform

... Antibodies to Image Solid tumors and Other Malignancies -- -- Supported by ... a unique target for the vascular imaging of tumors and tumor metastases in patients with cancer. ... ability to achieve unusually clear images of tumors in living animals in these studies supports the ...

Lab Study Finds Protein That May Inhibit Cancer Spread

... News) -- A protein produced by certain kinds of tumors inhibits the spread of cancer and could ... Boston had found previously that metastatic tumors prepare "landing places" for cancer in other ... In the new study, they found that non-metastatic tumors secrete a protein called prosaposin that inhibits ...

Potent metastasis inhibitor identified

... at Children's, has been finding that metastatic tumors prepare landing places in distant organs for ... he and his colleagues show that non-metastatic tumors secrete a protein called prosaposin -- which ... of prosaposin, they found, while metastatic tumors secreted very little. When the researchers ...

Mayo researchers: Dramatic outcomes in prostate cancer study

... of a majority of cancer cells and caused the tumors to shrink dramatically, allowing surgery. In both cases, the aggressive tumors had grown well beyond the prostate into the ... during surgery, came a greater surprise. "The tumors had shrunk dramatically," says Michael Blute, ...

Varian's RapidArc Radiotherapy Technology Enables Pioneering Cancer Treatments at Top Dutch Oncology Center

... ways to perform radiosurgery on benign acoustic tumors using fast and precise RapidArc(TM) radiotherapy ... boost to multiple brain metastases, pelvic tumors and small lung tumors are now being treated with RapidArc. "Our ...

New Treatment Option at The Sarah Cannon Cancer Center Provides Hope for Inoperable Tumors

... technology, we are giving new hope to those whose tumors were previously thought to be inoperable and ... Cannon Cancer Center now has the ability to treat tumors anywhere in the body, even the brain, spine, ... is ideal for treating both cancerous and benign tumors that are medically inoperable or surgically ...

Researchers identify 4 new targets for breast cancer

... or autotaxin. Invasive and/or metastatic tumors were present to varying degrees, with 45.5 percent of the tumors in the LPA3 strain metastasizing. A number of ... cancer that is invasive and metastatic, and some tumors that are estrogen-receptor positive. ER-positive ...

Ovarian Cancer Breakthrough Heralds New Era of Treatment

... Scientists identify cause of deadly tumors and predict life-saving developments could follow ... study, researchers decoded four granulosa cell tumors using "next generation" sequencing machines that ... Center. Researchers chose granulosa cell tumors because, unlike other cancers, they are ...

Researchers identify four new targets for breast cancer

... or autotaxin. Invasive and/or metastatic tumors were present to varying degrees, with 45.5 percent of the tumors in the LPA3 strain metastasizing. A number of ... cancer that is invasive and metastatic, and some tumors that are estrogen-receptor positive. ER-positive ...

UNC scientists identify growth factor as possible cancer drug target

... CHAPEL HILL, N.C. - To grow and spread, tumors need new blood vessels, a process called ... to inhibit VEGF are already in use. But not all tumors respond to the therapy initially or over the long ... is present in blood vessels of a wide variety of tumors provides us with a new target for drug design," ...

Medifocus, Inc. receives Authorization Approval from Health Canada to launch its pivotal Phase III clinical study of focused microwave heating for treatment of breast cancer in Canada

... treatment arm, almost 80% of all breast tumors treated had a tumor volume reduction of 80% or ... efficacy in the shrinkage of large breast tumors will facilitate increased breast conservation ... microwave energy to cause heating in cancerous tumors anywhere in the body reliably and repeatedly. The ...

Morphotek(R), Inc. Announces FDA Acceptance of Investigational New Drug Application for MORAb-004, a Monoclonal Antibody for the Treatment of Solid Tumors

... Targets Endosialin, a Protein Widely Expressed on tumors and Tumor Blood Vessel Cells EXTON, Pa., ... a protein expressed on cells associated with tumors and tumor blood vessel cells. The IND became ... vessels are required to provide blood flow to tumors for growth. Endosialin is expressed on pericytes ...

Oxygen + MRI might help determine cancer therapy success, researchers find

... of how well a patient will respond to treatment. tumors with little oxygen tend to grow stronger and ... level dependent) MRI, can detect oxygen levels in tumors without the need for an invasive procedure. The ... study, researchers took multiple images of breast tumors implanted just below the skin of rats, which were ...

I-SPY trial offers key insights into locally advanced breast cancer

... and survival. Locally advanced breast cancer tumors develop in younger patients, have a worse ... profiles of locally advanced breast cancer tumors predicted the response of the tumors to chemotherapy drugs given in advance of ....