Tumor in Medical News

Researchers effectively treat tumors with use of nanotubes

... of Medicine. "It's great if you can get the tumor to shrink, but the gold standard is to make the tumor shrink or disappear and not come back. It appears ... creating heat. If enough heat is conducted, tumor cells near the tubes begin to shrink and die. ...

Diagnostic tools and innovative therapies improve patient prognosis

... for debate. It is unknown if they emerge from the tumor itself, its micro-environment or if they are ... to 400 different VOCs were identified in either tumor cells or controls. The analysis revealed 120 of the compounds appeared in all tumor and control cells with a high confidence interval ...

Nanoparticle-delivered 'Suicide' Genes Slowed Ovarian Tumor Growth

... available; Diphtheria-encoding genes delivered to tumor site by nanoparticles; Laboratory research; ... ovarian cancer that has promise for targeting tumor cells and leaving healthy cells healthy," ... of this technique, the researchers measured tumor volume before and after treatment. They found ...

JNCI news brief: Antibody linked to chemotherapy drug inhibits ovarian cancer in lab

... In mice, the EphA2 immunoconjugate inhibited tumor growth by 85%󈟎% compared with that in ... proliferation and increased apoptosis of tumor cells. Chemotherapy drugs typically affect both tumor and normal tissues, which can result in side ...

Study provides documentation that tumor 'stem-like cells' exist in benign tumors

... tumors. Cells generated from the pituitary tumor cells had the same genetic makeup and ... into any of several types of cells. tumor stem-like cells appear to have the same ... of producing healthy cells, they propagate tumor cells. In this study, ...

New Gene May Signal Aggressive Breast Cancer

... Finding provides insight into tumor growth, metastasis, researchers say ... otherwise healthy cells began to look more like tumor cells, according to the study in the July 20 ... that the altered cells had less capacity for tumor growth and metastasis. According to the study, ...

New strategy in tumor treatment

... agent. This two-drug combination therapy kills tumor cells while normal tissues are well protected." ... go on to state, "Among the drugs used to kill the tumor cells, two -- thioguanine and fluorouracil (or ... tissues." To assess the selective killing of tumor cells when they were present in excess of normal ...

Cancer Patients Benefit From Speed, Accuracy of RapidArc Radiotherapy Treatments

... he learned that an aggressive type of brain tumor was hindering his speech and language functions. The tumor was removed surgically, and as is standard for ... previously possible. "Before my brain tumor was discovered, I could tell that my ...

Gene Connections Key to Brain Tumor Growth

... cancer." Bredel, who is director of the Brain tumor Institute Research Program at Northwestern ... is novel and may indeed be successful in other tumor types that so far have been reluctant to give us ... Markus Bredel, M.D., Ph.D., director, Brain tumor Institute Research Program, Feinberg School of ...

Peregrine Pharmaceuticals Reports Financial Results for Fiscal Year 2009

... in the initial cohort demonstrated an objective tumor response according to RECIST criteria. These ... in the initial cohort achieved an objective tumor response according to RECIST criteria. These ... in the initial cohort, achieved an objective tumor response according to RECIST criteria. These ...

Fluorescent probes may permit monitoring of chemotherapy effectiveness, Stanford study shows

... way to get attention. If physicians could watch tumor cells committing a form of programmed suicide ... against unwanted cell division, as occurs during tumor growth, said Salvesen, who collaborates with ... Bogyo and his colleagues again saw the many tumor cells undergoing apoptosis light up, but not the ...

Anti-angiogenesis treatment improves hearing in some NF2 patients

... patients to receive bevacizumab, treatment led to tumor shrinkage in nine, and six had 20 percent or greater reduction in tumor size. In those six patients, tumor shrinkage lasted from 11 to 16 months, longer ...

Drug Shows Promise in Nervous-System Tumor Treatment

... throughout the nervous system. The most common tumor is a vestibular schwannoma, which grows on the ... 10 NF2 patients with vestibular schwannomas. tumor shrinkage occurred in nine patients, six of whom had a 20 percent or greater reduction in tumor size. ...

Forsyth Medical Center participating in Avastin trial for new glioblastoma patients

... Avastin to treat glioblastoma, a fast-growing tumor of the brain or spinal cord. Forsyth Regional ... two Phase II studies that showed Avastin reduced tumor size in some glioblastoma patients. The new ... common and most aggressive type of primary brain tumor in humans, accounting for about half of all ...

European Medicines Agency (EMEA) Approves Cell Therapeutics, Inc.'s September Meeting Request to Discuss OPAXIO(TM) Marketing Authorization Application

... and its associated toxicities. Blood vessels in tumor tissue, unlike blood vessels in normal tissue, ... to their leaky blood vessels and trapped in the tumor bed allowing significantly more of the dose of chemotherapy to localize in the tumor than with standard paclitaxel. Once inside ...

Carbohydrate acts as tumor suppressor

... (glycans) that anchor cells into place act as tumor suppressors in breast and prostate cancers. ... resulted in a significant reduction in tumor activity. The research was published in the ... the laminin-binding glycans were restored and tumor formation decreased. "These results indicate ...

Purdue researchers create prostate cancer 'homing device' for drug delivery

... tumors and could provide a way to cut off the tumor blood supply, Low said. "A lot of new drugs ... which is found only on prostate cancer cells and tumor blood vessels, acts as the homing signal that the ... and has much easier penetration through a solid tumor to reach all of the cells inside, he said. It ...

6th Annual Neurosurgery Charity Softball Tournament Hits It Out of the Park For Pediatric Brain Tumor Research Fund

... Ill., July 1 /PRNewswire/ -- The Pediatric Brain tumor Research Fund of Columbia University Medical ... first pitches to Dan Palumbo, a young brain tumor survivor treated at Columbia. To learn more about The Pediatric Brain tumor Research Fund of Columbia University Medical ...

Newly appreciated membrane estrogen receptor important therapeutic target for breast cancer

... estrogen action through GPR30 allows for breast tumor cell survival, and not breast tumor cell proliferation." Prior studies by Filardo's ... through GPR30 had a more profound effect on tumor cell survival. They found that GPR30 promoted the ...

Study identifies biomarker that safely monitors tumor response to new brain cancer treatment

... A specific biomarker, a protein released by dying tumor cells, has been identified as an effective tool ... a combination of proteins and a drug to kill tumor cells, which triggers an ongoing immune response ... They found that a protein released by dying tumor cells may be used as a "biomarker" to gauge the ...

Bladder Cancer No Longer a Death Sentence

... further testing confirmed the invasive tumor had penetrated the muscle wall. "My doctor ... be cancer free. But his surgeon found that the tumor had grown outside the bladder wall and ... microwaves into tumors causing the destruction of tumor cells. The RAF destroyed the tumors, but he was ...

Peregrine Pharmaceuticals Completes Planned Patient Enrollment in Bavituximab Phase I Cancer Trial

... own immune system to recognize and act on the tumor and its supporting blood vessels, resulting in ... trials were very encouraging, with objective tumor response rates that compare favorably to ... lipid phosphatidylserine (PS) on the surface of tumor blood vessels. Since these phospholipids are ...

Cancer Researchers Link DICER1 Gene Mutation to Rare Childhood Cancer

... National Medical Center. "PPB is a tumor that appears to arise out of a localized area of ... to the normal copy of DICER1 in lung cells for a tumor to develop. When the research team looked at PPB ... the results: "We expected to see that the tumor cells had no DICER1 protein giving us a nice ...

U-M study finds voice box can be preserved, even with the largest cancers

... tumors are so large. We found that if a patient's tumor does not respond to chemotherapy, the patient can ... which is the standard of care. But if the tumor responded to the drugs, perhaps some of those ... designed to see if the cancer responds. If the tumor shrank by more than 50 percent after that first ...

Effective pain treatment for cancer patients?

... make nerve cells especially sensitive and enhance tumor growth. In animal tests, when the researchers ... cells, the sensitivity of the nerve cells and tumor growth were reduced. The results of the ... the prestigious journal Nature Medicine . tumor pain: new therapies are urgently needed For ...

Forsyth Medical Center's Derrick L. Davis Forsyth Regional Cancer Center to Take Part in Research Trial for Patients with Fast-Growing Brain Tumors

... Avastin to treat glioblastoma, a fast-growing tumor of the brain or spinal cord. This third phase of ... Avastin to treat glioblastoma, a fast-growing tumor of the brain or spinal cord. Forsyth Regional ... two Phase II studies that showed Avastin reduced tumor size in some glioblastoma patients. The new study ...

Study pinpoints novel cancer gene and biomarker

... each gene's activity in a set of lab-grown tumor cells. "When we 'knocked down' GOLPH3 expression ... sought to answer whether high GOLPH3 levels cause tumor cells to be more susceptible to rapamycin in ... human cancer cells. An experiment analyzing human tumor tissue for specific proteins suggested yes. The ...

Peregrine Pharmaceuticals Awarded Broad New U.S. Patent for Vascular Imaging Applications of Its PS-Targeting Platform

... that becomes exposed on the surface of tumor blood vessel cells. Since PS is typically not ... target for the vascular imaging of tumors and tumor metastases in patients with cancer. ... such as bavituximab preferentially bind to tumor blood vessels, which makes them ideal vehicles ...

Lab Study Finds Protein That May Inhibit Cancer Spread

... Tests in mice show prosaposin injections reduce tumor growth MONDAY, June 22 (HealthDay ... by secreting certain proteins that encourage tumor growth and attract feeder blood vessels. In the ... then added prosaposin to highly metastatic tumor cells and injected them into mice. Lung ...

Potent metastasis inhibitor identified

... Boston have isolated a potent inhibitor of tumor metastasis made by tumor cells, one that could potentially be harnessed as ... by secreting certain proteins that encourage tumor growth and attract feeder blood vessels. Now, he ...

Spinal Cancer Patient Finds New Hope at the Palo Alto Medical Foundation

... battle against metastatic breast cancer. A new tumor located in the sacrum, or upper part of the ... radiation therapy treatments for the new tumor at another facility. This precluded re-treatment ... PAMF, because Novalis Tx can accurately target a tumor while minimizing exposure of tissues and organs ...

Damon Runyon Cancer Research Foundation awards prestigious fellowships to 17 top young scientists

... Triapine, which may prevent the replication of tumor cells and is currently being tested in Phase II ... of a novel class of RNA molecules, lincRNAs, in tumor suppression. By dissecting the mechanism by which lincRNAs influence tumor suppressor pathways, she hopes to identify new ...

Targeting tumor behavior may lead to new liver cancer drugs

... agents that may block a particular kind of tumor behavior. The agents target multiple genes ... identifies agents that could potentially block tumor progression by striking multiple genes that are ... "We believe that targeting a certain type of tumor behavior might be helpful for liver cancer ...

Promising biomarker and candidate tumor suppressor gene identified for colorectal cancer

... Researchers have identified a new candidate tumor suppressor gene in colorectal cancer and examined ... downstream-regulated gene 4 (NDRG4) as a novel tumor suppressor and biomarker. The researchers ... knowledge, this is the first study to describe a tumor suppressor role for NDRG4 in cancer," the authors ...

Joan Massagué wins BBVA Foundation Frontiers of Knowledge Award in Biomedicine

... in the May edition of Nature, explain how tumor cells manage to enter the brain and form a new ... survive from the time they leave the primary tumor and infiltrate vital organs to the time when, ... is all-important, since this process whereby a tumor colonizes other organs is responsible for 90% of ...

RNA snippet suppresses spread of aggressive breast cancer

... metastasis. In samples where a patient's original tumor had not metastasized, the cancer cells retained high levels of the microRNA. But where the tumor had metastasized, the cancer cells came to ... in altering the clinical progression of a tumor or causing it to revert to a more benign state." ...

New approach for treating recurrent prostate cancer on the horizon

... kills small tumors is needed. Because tumor cells readily bind with certain peptides, ... highly specific radiopeptides that bind with tumor cells and treat them using specific therapeutic ... 177 Lu-DOTA-PESIN, which are also effective in tumor cell-killing, but can also cause damage to nearby ...

Hebrew University research leads to advanced trials of new cancer treatment

... that the H19 gene plays a significant role in the tumor development process by enabling tumor cells to survive under stress conditions, such as ... This survival supports the growth of the tumor and the development of metastases. The ...

New Treatment Option at The Sarah Cannon Cancer Center Provides Hope for Inoperable Tumors

... the tumor's position, detects any movement of the tumor or the patient, and automatically corrects radiation delivery. It then targets the tumor with multiple pin-point beams of high-energy ... cycle resumes its normal motion and the tumor can be confidently tracked again. This heightened ...

LSUHSC research finds single gene controls growth of some cancers

... proteins made by EBV are necessary for tumor cells to grow indiscriminately. This is ... responsible for the indiscriminate growth of tumor cells in these cancers. Their research shows ... activate EBV genes responsible for indiscriminate tumor cell growth. "We have shown that in vitro, ...