tubule in Medical News

Bioartificial Kidney Cuts Death Risk, Improves Outcomes

... found that short-term replacement of renal cell function using the renal tubule assist device (RAD) -- the living cartridge that's critical to the ... of hollow fibers lined with a type of kidney cell called renal proximal tubule cells, which reclaim vital electrolytes, salt, glucose and water, and ...

'Renal Assist Device' reduces risk of death from acute kidney failure

... Journal of the American Society of Nephrology. The experimental renal tubule assist device (RAD) appears safe and effective for desperately ill ... The RAD is a conventional blood filter device lined with human renal tubule cells, grown from donor kidneys. "The cells are made available to carry ...

Head-to-Head 96-Week Study Shows EPZICOM(R) is Comparable to Truvada(R) in Efficacy and Safety Measures in HIV Treatment-Naive Patients

... (4% vs. <1%). Prospective HLA-B*5701 screening was not employed in this study. One percent of patients receiving Truvada developed proximal renal tubule dysfunction (vs. 0% for EPZICOM). Overall, treatment-limiting adverse events were comparable between the two arms. Important Information about ...

New treatment option studied for bladder cancer

... common cancer, often obstructs tubules that connect the kidney to the bladder, says Dr. Coleman. While the cancer typically doesnt spread upward, tubule blockage damages the kidneys. Additionally, bladder cancer incidence peaks in the 60s and 70s when other diseases, such as type 2 diabetes and ...

Triptolide: A Potential Drug for Polycystic Kidney Disease

... arrest in certain cell types. Normal kidney tubule cells have a built in switch for regulating their ... development, cells destined to line a kidney tubule grow and divide until the tubule is formed, as sensed by fluid flow in the tubule. ...

New Hope for Kidney Failure

... -- or kidney failure -- occurs because of renal tubule cell death. When the researchers examined the ... high level of HGF actually protected the renal tubule cells. These cells play an important role in the ... that gene delivery of HGF to the proximal tubule may be an interesting approach in designing ...

Hope for Patients With Kidney Failure

... mice, they discovered the high level of HGF actually protected the renal tubule cells. These cells play an important role in the kidney's ability to ... the study researchers conclude that gene delivery of HGF to the proximal tubule may be an interesting approach in designing future strategies aimed at the ...

Chinese Medicinal Compound Stops Formation of Cysts in Polycystic Kidney

... compound. During normal kidney development, cells lining the kidney tubules continue growing and dividing until they receive a signal that the tubule is fully formed. The switch that turns on that signal consists of the growth regulatory proteins PKD1 and PKD2, located on hair-like cilia in the ...

Prestigious Wilson Award Goes To Yale Cell Biologist Joel Rosenbaum

... not flow in, because the cilia are missing, or the polycystins on the membrane are missing or ineffective, a signal is sent to the nucleus and the tubule cells divide—and continue to divide. PKD is, therefore, a cancer of the kidney, where cells that should not be dividing start to divide because of a ...

The Exposure Of Cadmium And Its Effects On Kidneys

... to calculate glomerular function. Urinary concentrations of calcium, human complex-forming protein, and N-acetyl-a-D-glucosaminidase--all markers of tubule function--were available for 813 women. The researchers additionally collected data on medications taken, smoking history, lead exposure, and ...