Silenced genes as a warning sign of blood cancer
... parts of the genetic material of tumor cells are switched
off by chemical labels called methyl groups. This ... the cancer inhibitors that are frequently switched
off. The study of these questions is a very ... the genetic material, the DNA, genes can also be switched
on or off by chemical labeling of the DNA or the ...
Olanzapine Long-Acting Injection (LAI) Efficacy and Safety Data Presented at American Psychiatric Association Annual Meeting
... that showed patients with schizophrenia could be switched
to olanzapine LAI from a previous antipsychotic, ... in schizophrenia, among patients who were switched
directly to olanzapine LAI and those who were ...
Of 264 total patients, 150 (56.8 percent) were switched
directly and the rest were tapered. The two ...
GOCE's 'heart' starts beating
... highly sensitive gradiometer instrument has been switched
on and is producing data. Forming the heart of ... seen from the gradiometer from the moment it was switched
on. All accelerometer sensor heads are working in ... sophisticated electric ion propulsion system was switched
on last week and continues to operate normally. ...
For Some, More Costly Care Is Not by Choice
... plans through Harvard Pilgrim but whose employers switched
them to a high-deductible health plan when ... plan.
About one-third of the families who were switched
to a high-deductible plan had a child with a ... likely than families in higher-income areas to be switched
to a high-deductible plan.
Families with ...
Low-income families with sick children often enrolled in high-deductible health care plans
... Harvard Pilgrim, but whose employers later switched
them to a high-deductible health plan when ... see what kinds of families were most likely to be switched
to high-deductible plans.
Overall, about a third of those who were switched
to high-deductible plans had a child with a ...
Need for Health Care Reform Escalates; One in Four Americans Skip Care When Sick or Injured
... plans to save money. Of the 16 percent who switched
physicians in the last year, one in four switched
due to costs. Three in 10 switched
medications in the past year; 38 ...
DNA Solves Switched at Birth Mystery ... After 57 Years
... when 57 year old Fred George discovered he was switched
at birth. Fred's father, John George, ... in a Scottish Presbyterian family of five, if not switched
"I was accidentally placed in ... by a nurse's simple mistake in the autobiography, switched
at Birth: My Life in Someone Else's World (ISBN- ...
Scientists Unravel Mystery of Tamoxifen Resistance
... study, Carroll's team found how this gene can be switched
on and off.
The switch for the HER2 gene is ... called PAX2. "PAX2 is the handle that keeps HER2 switched
off," he said.
If PAX2 isn't there -- or is ... between PAX2 and AIB-1 determines whether HER2 is switched
Concern From Doctors Regarding the Cardiovascular Safety of GlaxoSmithKline's Avandia Increases Nine-Fold Following Publication of Meta-Analysis
... Nearly Three-Quarters of Physicians Have switched
Patients to Merck's Januvia, According to a ... nearly three-quarters of physicians say they
patients to Merck's Januvia as a result of the ... three-quarters of physicians say they have switched
Januvia as a result of the Avandia ...
Ustekinumab Phase 3 data show long-term improvement of chronic plaque psoriasis
... with 64 percent and 62 percent of patients switched
to placebo (P≤0.001 for 45 mg comparison; P ... continue treatment with ustekinumab or were switched
Through week 12 (the ... AE, compared with 56 and 48 percent of patients switched
to placebo. Serious AEs were observed in 0 and 1 ...
A New Government-Run Plan Would Impose Significant Financial Losses on California Hospitals
... hospitals in California would face significantly higher losses if patients switched
to a government-run plan and the costs incurred for uncompensated care ... in California would face losses of more than 30 percent if all patients switched
to a government-run plan that paid Medicare rates.
National Pharmacy Omnicare Pays 'Unusual' Settlement to Resolve Charges of Generic Drug Switching in Delaware Nursing Homes, Resulting From 'Qui Tam' Lawsuit
... infrequently prescribed, and had no maximum prices. Allegedly, Omnicare switched
patients' prescriptions for ranitidine tablets to the expensive capsules -- costing taxpayers up to 400% more. For Prozac®, Omnicare allegedly switched
prescribed capsules to tablets, also to reap profits at taxpayers' ....
Deloitte Comparative Effectiveness Study Evaluates Potential Savings Opportunities for U.S. Health Care System
... prescription did so because of cost concerns.
Three in 10 say they switched
medications in the last 12 months; 38 percent of these switched
to save money.
Eight in 10 say they would consider switching from ...
Emergency Consultants Inc. switches to Learn.com to deliver Continuing Medical Education (CME) courses to physicians
... a leader in emergency physician recruiting, staffing, and management, has switched
to the LearnCenter platform to offer Continuing Medical Education (CME) ... a leader in emergency physician recruiting, staffing, and management, has switched
to the LearnCenter platform to offer Continuing Medical Education (CME) ...
New drug shows promising results for psoriatic arthritis
... than 10 percent improvement in swollen and tender joints at week 16 were switched
from placebo to 50 mg golimumab or from 50 mg to 100 mg. The primary end ... and ACR70 responses and those who initially showed little improvement and switched
from placebo to golimumab or increased their dosage also showed ...
Gut instinct: Salmonella bacteria's molecular tactics to cause illness
... by the epithelial cell, this secretion system is no longer needed and is switched
off. At the same time, another system, SPI-2 is activated and will respond ... activated can the proper activation of genes for intracellular survival be switched
on and delicately maintained.
The sequence of events appears as ...
Osteoporosis Drug Seems to Shrink Breast Tumors
... five years after standard treatment and women who took tamoxifen but then switched
to an aromatase inhibitor after initial treatment. "The data are still ... but it does show a statistically significant advantage in [women who were switched
from tamoxifen to an aromatase inhibitor] but not in [women who took ...
New Survey: Painful Economy Puts Health Care Pinch on Young Adults
... of the high price of gas. Furthermore, 66 percent of older Americans switched
from a brand named drug to a generic in the last 12 months and 54 ... samples as a way to reduce their medication costs; nearly 60 percent switched
from a brand name drug to a generic, while 40 percent used an ...
'Superbug' breast infections controllable in nursing mothers, UT Southwestern researchers find
... she does not immediately need antibiotics against MRSA, but can be switched
to them if tests reveal she has MRSA.
The study was designed to ...
During the study, when tests showed that a woman had MRSA, she was switched
to vancomycin, an antibiotic effective against it.
About 2 percent to ...
Walgreens to Pay $35 Million to U.S., 46 States & Puerto Rico to Settle Medicaid Prescription Drug Fraud Allegations
... to pay $35 million to settle claims that from
2001 to 2005, it improperly switched
patients to different versions of the
prescriptions drugs Ranitidine, ... which operates over 5,000 retail pharmacies throughout the
the prescriptions for Medicaid patients who were prescribed
150 mg or 300 ...
Looping genes may hold a key to understanding breast cancer
Our studies suggest that BRCA1 looks a bit like a bow when the gene is switched
off, and that part of this bow' disappears when the gene is switched
on, Dr Brown said.
Interestingly, the shape of the bow changes in ...
CVS, America's Largest Pharmacy Chain, Pays Nearly $37 Million to Settle Federal and State Generic Drug Switching Charges
... profits by
evading federal and state price ceilings when it unlawfully switched
forms. Twenty-four states also entered separate settlements with ... prescribed
ranitidine capsules had no maximum prices. When CVS switched
prescriptions from ranitidine tablets to the expensive capsules, ...
Cell recycling protects tumor cells from anti-cancer therapy
... might also be an attempt by the cells to survive. Autophagy is also switched
on specifically, for example, when the cell does not have enough nutrients ... the role of autophagy in cancer treatment. To this end, the investigators switched
off a number of genes in tumor cells that are essential for autophagy. ...
What gives us fingertip dexterity?
... The researchers found that the muscle coordination pattern clearly switched
from that for motion to that for force (~65 ms) before contact. ... modeling and analysis revealed that the underlying neural control also switched
between mutually incompatible strategies in a time-critical manner.
Bisexuality not a transitional phase among women, according to new research
... heterosexual as their identities.
Seventeen percent of respondents switched
from a bisexual or unlabeled identity to heterosexual during the study -- but more than half of these women switched
back to bisexual or unlabeled by the end.
By year 10, most of the ...
Amarin Announces Completion of Comprehensive Data Analysis From Phase III Huntington's Disease Program
... long term Miraxion group (12-months
treatment) and those patients who had switched
to Miraxion at 6-months.
Treatment codes were not broken at the switching ... in which patients initially randomized to treatment with
placebo had been switched
to Miraxion and treated for 12 months. After
switching to Miraxion, these ...
Smac-ing lung cancer to death
... part of the cells programmed cell death machinery. When that machinery is switched
on, Smac is released from the mitochondria and triggers the pathway that ... advantage turns out to be a fatal flaw, because the same pathway can be switched
to apoptosis by Smac mimetics, said Wang. So, for some cancers, we might ...
Pelosi, Democratic Leaders Remarks Today at News Conference on Legislative Accomplishments
... opponent, of this legislation passing and with a public option in it. Because they know that the glory days are over of them. The leverage has switched
to the consumer -- Congress and the President will remove the insurance industry from coming between the patient and his or her doctor.
House Measure Proves Healthcare Legislation Will Fund Abortion, Says Family Research Council Action
... or private plans passed in the committee, Chairman Henry Waxman (D-Calif.) called a re-vote on the amendment and Tennessee Democrat Bart Gordon switched
his vote to the pro-abortion side.
"Even those who claim abortion is not included cannot possibly deny that abortion is explicitly in the ...
Does the Crowded TNF Market Really Need Two New Agents? Rheumatologists Provide Insight in the Wave One Report of LaunchTrends(TM): SIMPONI and CIMZIA
... More than one-half of surveyed physicians have prescribed Simponi while less than one-third report trial of Cimzia. Over 80% of Simponi patients were switched
from other biologics (primarily Humira) while a higher percent of the Cimzia patients were biologic naive. The majority of Rheumatologists see both ...
Researchers Discover the Tale Behind Short Dogs
The retrogene in the short-legged dogs produces too much of the FGF4 growth protein, which the team believes may cause growth receptors to be switched
on at the wrong time during fetal development. This may be behind the known calcification of growth plates that prevents these breeds' legs from ...
FDA Ruling on Mercury Fillings Falls Short
... attitude toward children and the unborn will not go unanswered. We will see FDA in court."
Most consumers, and most dentists, have already switched
to the main alternative, resin composite. The FDA rule destroys a dental myth that the mercury becomes inert in the mouth; FDA says the vapors from ...
Scientists Track Impact of DNA Damage in the Developing Brain
... DNA damage response plays in preventing neurological disease," the investigators wrote.
The study also marks the first time researchers have switched
off a pathway for repairing damaged single DNA strands in an organ system, in this case the mouse brain and nervous system. While the results suggest ...
Medicare Drug Plan Still Needs Work
... too, and has actually left some people worse off."
He noted that low-income seniors who are "dually eligible" for both Medicare and Medicaid were switched
from Medicaid drug coverage to Medicare Part D. In California, that shift resulted in seniors losing a relatively rich array of benefits. In general, ...
For Treatment of Rheumatoid Arthritis, Surveyed Rheumatologists and Patients Differ In Their Perception of Bristol-Myers Squibb's Orencia
... to TNF-alpha inhibitors. However, this high perception may be attributed to the fact that an overwhelmingly majority of Orencia patients have switched
to the drug after failing treatment with a TNF-alpha inhibitor.
The new report entitled Brand Perceptions in Rheumatoid Arthritis also ...
With Medicare Plan, Drug Spending May Be Up
... drug coverage from their former employer for the entire four years of the study, considered the control group. People in the first three groups all switched
to Part D as of 2006.
"The impact of Part D on medical spending really depended on prior drug coverage," Zhang said.
People who'd had no ...
Cellular Technology Extends the Boundaries of E-healthcare, Says Frost & Sullivan
... through which information is transmitted."
The various technologies used for the transmission of information in healthcare include the Public switched
Telephony Network (PSTN), Radio Frequency Identification (RFID), cellular, Wireless Fidelity (Wi-Fi) and Bluetooth. Most organisations choose ...
Novo Nordisk Insulin Analogs Have Proven Safety Profiles
... 1 diabetes, diabetic ketoacidosis. Dose and timing of administration may need to be adjusted to reduce the risk of hypoglycemia in patients being switched
to Levemir from other intermediate or long-acting insulin preparations.
NovoLog(R) has a more rapid onset and shorter duration of action than ...
Horse Study: RBC Life Sciences' Antioxidant, Microhydrin, Reduced Lactic Acid Buildup and Improved Hydration During Strenuous Exercise
... supplement. At the end of this weeklong preparation, all the mares underwent a standard exercise test on an equine treadmill. The equine center later switched
the control group of mares and retested.
The study found that the mares who received Microhydrin antioxidant in their feed had more than 13% ...
Pages to Doctors Don't Always Hit the Mark
... shift, 22 percent were sent in the evening and 21 percent during scheduled academic half-days.
"A lot of them are examples of numbers being switched
or a paper schedule that hadn't been updated," Wong said.
Although these misdirected pages did result in "delays and inefficiencies," the authors ...