Spondylitis in Medical News

IFX anti-TNF therapy associated with clinical benefit over 5 years in patients with active AS

... therapy, 61.8% of patients with ankylosing spondylitis (AS) showed substantial clinical benefit (ASAS40, ... 96-week open-label EASIC (European Ankylosing spondylitis Infliximab Cohort) trial had previously ... randomised controlled trial ASSERT (Ankylosing spondylitis Study for the Evaluation of Recombinant ...

SIMPONI(TM) (golimumab) Receives FDA Approval as First Once-Monthly Anti-TNF for Treatment of Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis

... arthritis, psoriatic arthritis and ankylosing spondylitis are chronic inflammatory diseases that result in ... arthritis, psoriatic arthritis and ankylosing spondylitis who had previously received a wide variety of ... of adult patients with active ankylosing spondylitis SIMPONI is available in two ...

Increased cancer risk following the use of radioactive Radium-224 in the therapy

... Ankylosing spondylitis (Bechterew's Disease) is a painful chronic ... a long-term follow-up study of 1,471 ankylosing spondylitis patients, whose disease symptoms were treated ... 224Radium. A control cohort of 1,324 ankylosing spondylitis patients treated without the use of radioactive ...

Data Show that Abbott's HUMIRA(R) (adalimumab) Reduced the Signs and Symptoms of Ankylosing Spondylitis Up to Three Years

... in Paris. "There is no cure for ankylosing spondylitis and the goal of therapy is to relieve back and ... death caused by malignancy. About Ankylosing spondylitis (AS) AS is a rheumatic condition that affects ... men than in women. Ankylosis means "fusion" and spondylitis means "inflammation of the spine." Advanced AS ...

Adalimumab therapy effective in AS, RA and PsA patients refractory to other anti-TNF therapies

... is effective and well-tolerated in ankylosing spondylitis (AS), rheumatoid arthritis (RA) and psoriatic ... have a mean reduction in BASDAI (Bath Ankylosing spondylitis Disease Activity Index) of -2.4 following ... options for their diseases." Ankylosing spondylitis 61% of AS patients who had lost their initial ...

Abbott Study Examines Rates of Uveitis (Inflammation of the Eye) in Ankylosing Spondylitis Patients Treated with HUMIRA(R) (adalimumab)

... Percent of People with Ankylosing spondylitis (Spinal Arthritis) ABBOTT PARK, Ill., Nov. 8 /PRNewswire-FirstCall/ -- A study of ankylosing spondylitis (AS) patients treated with Abbott's HUMIRA(R) ... to patients treated with placebo. Ankylosing spondylitis is an inflammatory disease of the spine, and may ...

UT rheumatologists discover 2 genes related to disabling form of arthritis

... of Queensland, led research done by the Triple A spondylitis Consortium Genetic Study (i.e. the TASC or Australo-Anglo-American spondylitis Consortium). The international team of ... steps closer to fully understanding ankylosing spondylitis or AS, a chronic form of arthritis that attacks ...

LegalView Informs Patients of Possible Cimzia Cancer Link, Drug Commonly Used to Treat Arthritis

... rheumatoid/psoriatic arthritis, Crohn's disease, psoriasis, ankylosing spondylitis and juvenile idiopathic arthritis -- should speak to a medical ... juvenile idiopathic arthritis, psoriatic arthritis, ankylosing spondylitis and plaque psoriasis. In addition to the potential for causing possibly ...

New Long-Term HUMIRA(R) (adalimumab) Data Show Up to Seven-Year Efficacy with Combination Treatment for Rheumatoid Arthritis

... arthritis (RA), psoriatic arthritis (PsA), plaque psoriasis, ankylosing spondylitis (AS) and Crohn's disease in the United States and Europe. HUMIRA resembles ... is indicated for the treatment of adults with severe, active ankylosing spondylitis who have had an inadequate response to conventional therapy. HUMIRA is ...

HUMIRA(R) (adalimumab) Data Show That Treating Early Rheumatoid Arthritis With Combination Treatment Resulted in Cost Savings From Improved Work Productivity

... arthritis (RA), psoriatic arthritis (PsA), plaque psoriasis, ankylosing spondylitis (AS) and Crohn's disease in the United States and Europe. HUMIRA resembles ... is indicated for the treatment of adults with severe, active ankylosing spondylitis who have had an inadequate response to conventional therapy. HUMIRA is ...

Chlamydia may play role in a type of arthritis

... that share clinical features such as inflammatory back pain and inflammation at sites where tendons attach to bone. It includes ankylosing spondylitis (AS), psoriatic arthritis, inflammatory bowel-disease-related arthritis, reactive arthritis (ReA) and undifferentiated spondylarthritides (uSpA). ...

Driven by Sales of Enbrel, Remicade and Humira, spondyloarthropathies Drug Market Grew to Nearly $2 Billion in 2008

... reactive arthritis drug sector is markedly different than the sectors for the other two diseases. While the combined market in 2008 for ankylosing spondylitis and psoriatic arthritis was approximately $1.8 billion, the reactive arthritis drug market in that year was only $3 million, and TNF-alpha inhibitors ...

Rheumatoid Arthritis Therapeutics in Taiwan

... (Logo: http://www.newscom.com/cgi-bin/prnh/20081117/FSLOGO ) Frost & Sullivan, Research Analyst Sushma Rajan says, "Besides ankylosing spondylitis (AS) and system lupus erythmatosus (SLE), rheumatoid arthritis (RA) is one of the most common rheumatic diseases in Taiwan, with an incidence of 0.35 ...

Medarex to Receive Milestone Payment for Approval of STELARA(TM) (Ustekinumab) for the Treatment of Moderate to Severe Plaque Psoriasis

... approval as a once-monthly subcutaneous anti-TNF-alpha human antibody in the U.S. and in Europe for the treatment of rheumatoid arthritis, ankylosing spondylitis and psoriatic arthritis, and in Phase 2 for the treatment of ulcerative colitis; and CNTO 95, an anti-integrin human antibody in Phase 2 development ...

MEDVERSATION(TM) Website Launched by Centocor to Facilitate Physician-Patient Dialogue About Drug Benefits and Risks

... rheumatology and dermatology. REMICADE has demonstrated broad clinical utility in Crohn's disease (CD), rheumatoid arthritis (RA), ankylosing spondylitis (AS), psoriatic arthritis (PsA), ulcerative colitis (UC), pediatric Crohn's disease (PCD) and psoriasis (PsO). The safety and efficacy of REMICADE ...

FDA Demands Tougher Warnings on Immunosuppressive Drugs

... approved to treat several conditions including rheumatoid arthritis, juvenile idiopathic arthritis, psoriatic arthritis, plaque psoriasis, ankylosing spondylitis and Crohn's disease. All four drugs already carry black-box warnings related to different safety issues, including fungal infections. "FDA has ...

Centocor, Inc. Submits Application to FDA Requesting Approval of Golimumab for the Treatment of Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis

... by psoriatic arthritis, most commonly between the ages 30 and 50, in the peak of their productive years. About Ankylosing Spondylitis Ankylosing spondylitis (AS) is a painful and progressive form of spinal arthritis and symptoms of inflammatory back pain often first present in people before age 35. It ...

CV risk management should be mandatory in RA and other types of inflammatory rheumatic disease

... Paris, France, Friday 13 June 2008: Rheumatoid arthritis (RA), ankylosing spondylitis (AS) and psoriatic arthritis (PsA) patients should undergo compulsory cardiovascular (CV) risk management and existing CV risk calculators should be ...

Marc Feldmann and Sir Ravinder Maini win Dr. Paul Janssen Award for Biomedical Research

... target for treatment not only in rheumatoid arthritis but also other chronic inflammatory conditions, such as inflammatory bowel disease, ankylosing spondylitis and psoriasis. This discovery suggested that other cytokine messenger molecules are also good treatment targets and has led to an emerging branch of ...

Abbott Announces HUMIRA(R) (adalimumab) Approved in Japan for the Treatment of Rheumatoid Arthritis

... HUMIRA is the only fully human monoclonal antibody approved for the treatment of rheumatoid arthritis (RA), psoriatic arthritis (PsA), ankylosing spondylitis (AS), Crohn.s disease and plaque psoriasis (Ps) in the United States and Europe. HUMIRA is also approved for the treatment of juvenile idiopathic ...

Arthritis sufferers fund arthritis research

... Thomas will be the inaugural recipient of the $300,000 three-year fellowship, which will fund his research investigating the causes of ankylosing spondylitis (AS). This is a form of arthritis affecting the spine resulting in joint fusion and immobility, and osteoporosis, a disease characterised by bone ...

Centocor, Schering-Plough Revise Agreement Covering REMICADE, Golimumab

... and ulcerative colitis. Golimumab is currently in Phase 3 trials for the treatment of rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis and is being investigated for administration by either monthly subcutaneous injection or every 12-week intravenous (IV) infusion. The companies ...

Abbott's HUMIRA(R) (adalimumab) Honored With Prestigious Galen Prize for Innovation in Patient Care

... fully human antibody. HUMIRA is approved for use in the treatment of moderate to severe rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis and moderate to severe Crohn's disease. The Galen Prize, considered an equivalent to the Nobel Prize and awarded by Prix Galien USA, is one of the ...

New Device Developed For Treating Cervical Spondylitis

... to have developed a device to facilitate keyhole surgery for cervical spondylitis and disk prolapse, in what is being regarded as a breakthrough in spinal ... create a revolution in spinal surgery," Dev told IANS here. "In both spondylitis and prolapsed disk, it is the compression of the disk that leads to ...

Ankylosing spondylitis may not be detected in children

... Childhood ankylosing spondylitis may be more common than thought of and may remain undetected because of this//, says a new study in US. Ankylosing spondylitis or arthritis of the spine is a disease that may affect young children. ...

Does Anti-TNF Therapy Control Ankylosis ?

... resulting from inflammation of joints. It causes swelling and pain resulting in limited movement.// Spondylarthritis (SpA), ankylosing spondylitis (AS), psoriatic arthritis (PsA), and inflammatory bowel disease are all associated rheumatic diseases collectively known as ...

NICE supports application of advanced biological therapies as treatment option for acute psoriasis

... response to, or who have proved intolerant of, methotrexate. Enbrel has not been studied in children aged less than 4 years. Severe active ankylosing spondylitis in adults who have had an inadequate response to conventional therapy. Since the product was first introduced, serious infections, some ...

Treat Spondylitis With Keyhole Surgery

... neurosurgeon in Lucknow has today developed a new drill to help with the keyhole approach to spinal surgery especially keyhole surgery for// cervical spondylitis and disk prolapse. Ravi Dev, a young associate professor in the department of neurosurgery at King George's Medical University (KGMU), has ...