Is somatic hypersensitivity a predictor of irritable bowel syndrome?
... of IBS, conflicting evidence exists regarding somatic hypersensitivity in this patient population. ... have found no evidence for heightened somatic pain sensitivity in IBS patients. Also, others ... conflicting findings may result from differing somatic pain testing procedures. Previous studies have ...New oncogene gives valuable insight into hepatocellular tumors in humans
... 23 April: The first identification of GP130 somatic activating mutations* in human tumours was ... Denmark. Identification of recurrent somatic mutation activating GP130 in inflammatory ... with obesity and alcohol intake. Recently, somatic mutations were identified that activated GP130 in ...New advancements in the use of adult, embryonic stem cells for tissue regeneration
... The recently acquired ability to reprogram adult somatic cells to ESCs in culture ("induced pluripotent ... concerns surrounding the destruction of somatic cell nuclear transfer embryos to make personal ... differentiation and survival time of reprogrammed somatic cells, and the need to develop methods to ...21st Congress of the College of Neuropsychopharmacology, Aug. 30-Sept. 3, 2008, Spain
... and academic career, social functioning and somatic health throughout life, frequently associated ... 290 billion euros (Wittchen et al., 2005). Unlike somatic diseases with their typically high direct costs, ... recognized and treated, the treatment of comorbid somatic illnesses is usually less efficient and therefore ...St. Jude finds 'dancing' hair cells are key to humans' acute hearing
... theoriescalled stereociliary motility and somatic motilitythat have resulted from previous studies ... of cilia extending from the outer hair cells. The somatic motility theory proposes that the sound signal is ... Since the prestin protein is the key component of somatic motility, in previous experiments Zuo and his ...Mutation database helps personalized treatment of lung cancer
... database brings together data on all the known somatic mutations (tumor derived - tumor specific) in a ... called epithelial growth factor receptor (EGFR). somatic mutations in this cell-surface molecule are known ... the assumption that a comprehensive list of all somatic EGFR mutations coupled with data on the response ...St. Jude psychologist says most children with cancer are well-adjusted
... A team led by Phipps examined self-reported somatic symptoms of 120 children with cancer who had ... medical treatment at least six months previously. somatic symptoms are physical problems such as loss of ... with cancer and healthy controls in self-reported somatic symptoms. In fact, cancer patients reported ...Dairy Veterinarians Highlight Need for Improved Methods for Detecting Mastitis
... of differential inflammatory cell counts in addition to the traditional somatic cell count to diagnose mastitis." Introduced in the 1960s, somatic cell count method measures the total number of leukocytes (white blood ...Scientists Turn Skin Cells Into Motor Neurons in ALS Patients
... of their motor neurons." The scientists had originally planned to use somatic cell nuclear transfer (SCNT), or "therapeutic cloning," to try to ... big question on everyone's mind is whether iPS will eliminate the need for somatic cell nuclear transfer. Eggan said it won't. "There are still several ...Public funding impacts progress of human embryonic stem cell research
... treatments, it explicitly banned the use of stem cells derived from somatic cell nuclear transfer from 2002 to 2006. Beginning in 2006 scientists were allowed to use stem cells from somatic cell nuclear transfer, but under strict regulatory guidelines. That may ...Somanetics Reports Financial Results for the First Quarter of Fiscal 2008
... Somanetics began commercial shipments of its new sensors for cerebral and somatic monitoring. These sensors are tailored to the small size and head shapes ... experience in the first quarter with the new, smaller cerebral and somatic sensors and the potential for the Company to exceed its original plan ...New interdisciplinary volume focuses on advances in stem cell research
... 5-8 chapters on a specific topic: Germ Cells and Totipotency, Niches and Asymmetry, Embryonic Development and Multipotent Progenitors, Reprogramming somatic Cells, Gene Expression and Transcriptional Networks, Epigenetics, Adult Stem Cells, Neural Stem Cells and Brain Tumors, Stem Cells and Cancer, and ...World first: Chinese scientists create pig stem cells
... stem cells, are capable of developing into any type of cell in the body. It is the first time in the world that this has been achieved using somatic cells (cells that are not sperm or egg cells) from any animal with hooves (known as ungulates). The implications of this achievement are ...Somanetics Announces New FDA 510(K) Clearance
... the INVOS System have been shown to improve outcomes after surgery. In neonates, infants and children, cerebral and somatic rSO2 provide noninvasive indications of oxygen changes in the cerebral and peripheral circulatory systems and may provide an early indication of ...UCSF Team Closer to Creating Safe Embryonic-Like Stem Cells
... into the genome, but promote self-replication and have the potential to induce pluripotency," Blelloch says. "They do their thing -- turn a somatic cell into an embryonic stem cell-like one -- and then they're gone." "MicroRNAs give us a new tool to manipulate the fate of ...UCSF team closer to creating safe embryonic-like stem cells
... into the genome, but promote self-replication and have the potential to induce pluripotency," Blelloch says. "They do their thing -- turn a somatic cell into an embryonic stem cell-like one -- and then they're gone." "MicroRNAs give us a new tool to manipulate the fate of cells," Blelloch ....Classifying concussions could help kids
... child's symptoms across time. Post-concussive symptoms, according to Dr. Yeates, can be divided into three groups: somatic, cognitive, and emotional. somatic symptoms like headaches and fatigue generally resolve themselves quickly. However, cognitive symptoms like trouble paying attention and forgetfulness ...Nightmares increase risk of further suicide attempts
... attempt suicide again, compared with those who do not have nightmares. The study included 165 patients aged 18-69 years, who were being treated at somatic and psychiatric departments following a suicide attempt in Sweden. Psychiatric interviews and self-assessments were carried out as part of the study ...First Commercially Cloned Dog Delivered to Florida Family
... sole, worldwide license for the cloning of dogs, cats and endangered species. The license was granted by Start Licensing, Inc. and applies to the somatic cell nuclear transfer (SCNT) cloning patents developed at the Roslin Institute for the cloning of Dolly the sheep. ### Read the full story at ...Study Showed New Episodes of Depression Delayed in People Taking Cymbalta(R)
... symptom severity during the 52-week maintenance phase as measured by Visual Analog Scales (VAS) for pain and the Symptom Questionnaire- somatic Subscale (SQ-SS), compared with those taking placebo (p-values > .05). -- The proportion of duloxetine-treated patients who ...Scientists take cancer research back to the basic molecular level
... of tumor biology and signaling pathways advances, so too does our ability to molecularly characterize individual tumors and identify germ line and somatic determinants of patient prognosis and response," said conference chairperson Gordon B. Mills, M.D., Ph.D., chairman of the Department of Molecular ...Cymbalta Receives European Approval for the Treatment of Generalised Anxiety Disorder
... Results from a Placebo- and Active-Controlled Trial. Int Clin Psychopharmacol 2007: 22(3):167-74. 4 Nicolini H, et al. Improvement of psychic and somatic symptoms in adult patients with generalized anxiety disorder: Examination from a duloxetine, venlafaxine extended-release, and placebo-controlled ...Caris Diagnostics Providing KRAS Mutational Analysis for Colon Cancer Patients
... developed by Amgen. This assay, which can be performed on biopsies taken for the initial cancer diagnosis, identifies those patients who have somatic mutations in KRAS, which is associated with a lack of response to Erbitux or Vectibix. This prognostic information has recently been validated in a ...UCSF receives funding for building from California stem cell agency
... goal of turning these discoveries into therapies. This is an unprecedented opportunity." In 1999, UCSF was the first U.S. university to carry out somatic cell nuclear transfer, which also is known as therapeutic cloning, and in 2001, was the second, after the University of Wisconsin, to derive human ...Therapeutic cloning treats Parkinson's disease in mice
... to reduce transplant rejection and enhance recovery in other diseases and in other organ systems. In therapeutic cloning or SCNT, the nucleus of a somatic cell from a donor subject is inserted into an egg from which the nucleus has been removed. This cell then develops into a blastocyst from which ...Molecular alliance that sustains embryonic stem cell state
... in stem cell research, said, "Klf4 is a transcription factor that came to prominence recently because it was one of four factors used to reprogram somatic cells back to the pluripotent state seen in embryonic stem cells. "The mystery of the role of Klf4 has been revealed in studies by Huck Hui and ...Yale study offers insight into possible cause of lymphoma
... mutations and an increased risk of cancer." The lymph system is made up of infection-fighting B cells. Schatz and his colleagues examined the somatic hypermutation (SHM) process, which introduces random mutations in B cells' antibody genes to make them more effective in fighting infection. SHM ...UCLA stem cell scientists reprogram human skin cells into embryonic stem cells
... medicine, Plath said. These new techniques to develop stem cells could potentially replace a controversial method used to reprogram cells, somatic cell nuclear transfer (SCNT), sometimes referred to as therapeutic cloning. To date, therapeutic cloning has not been successful in humans. However, ...Scientists Reprogram Human Skin Cells Into Embryonic Stem Cells
... the researchers said. These new techniques to develop stem cells could potentially replace a controversial method to reprogram cells called somatic cell nuclear transfer (SCNT), sometimes referred to as therapeutic cloning. To date, therapeutic cloning has not been successful in humans. ...