sheath in Medical News

Tysabri May Treat Myelin Sheath Damage From MS

... and stabilize damage done to the myelin sheath in people with multiple sclerosis (MS), a study ... by MS patients are caused by damage to the myelin sheath that surrounds and protects nerve cells. In ... and possibly restore some of the damaged myelin sheath that protects nerve fibers. Results from this ...

Safe Options for Cardiac Lead Removal: Study Published in Heart Rhythm Journal

... that a peer-reviewed study demonstrates Spectranetics' excimer laser sheath safely and effectively assists removal of pacing and defibrillator leads. ... and continue to receive clinical validation. The Spectranetics Laser sheath (SLS(R) II) use "cool" ultraviolet light to safely, effectively and ...

Minnesota partnership advances potential MS therapy

... sclerosis is a progressive disease, caused by damage to the myelin sheath that surrounds nerves. It can affect the brain and the spinal cord, ... rHIgM22 antibody initiates the re-growth or repair of the damaged myelin sheath but has yet to be tested in patients. The initial synthetic production ...

Viral Therapy Slows Pediatric Tumors in Mice

... viral therapy, dubbed rQT3, slowed neuroblastoma and peripheral nerve sheath tumors in mice, according to findings published in the Feb. 15 issue of ... most often striking those under age 5. Malignant peripheral nerve sheath tumors affect the connective tissue surrounding nerves. Researchers at ...

MS that runs in families appears more severe than non-familial MS

... this, we must do further investigation. MS destroys myelin, the fatty sheath that protects nerve fibers carrying message traffic from various muscles ... nervous system. For reasons currently unknown, in some people the myelin sheath breaks down, resulting in destruction of the nerve fibers and the symptoms ...

Aurora Physician Recognized for Multiple Sclerosis Care

... these factors and the disease have been determined. Multiple sclerosis is a disease where the body's immune system attacks the protective sheath surrounding the nerves. Symptoms can include blurred vision, loss of coordination and short-term or long-term memory loss. Aurora Health Care ...

CPC Strengthens Foundation as a Closure Products Company with its Vertically Integrated Product Pipeline

... announced today it will alsi gueo design and develop new vascular closure applications based upon a broader range of French sizes (i.e., introducer sheath diameters). The MedClose(TM) VCS design has the capabilities to be rapidly adapted to not only focus on its core VCS application for vascular ...

Prescribing sunshine for multiple sclerosis?

... potential treatments. Multiple sclerosis (MS) results from a failure of the body to recognize itself. The immune system attacks and destroys the sheath that protects nerve fibres, as if it were a foreign body or infection. Vitamin D, which is produced in the skin in response to natural sunlight, is ...

Research Shows Plasma Exchange Helps Multiple Sclerosis Patients

... is cleared, the body has the opportunity to repair itself. Multiple sclerosis is a disease where the body's immune system attacks the protective sheath surrounding the nerves. The National Multiple Sclerosis Society estimates 400,000 people in the United States have the disease. There is no cure for ...

Fat-Derived Stem Cells Might Treat MS

... at the University of California, San Diego, said in a news release. In people with MS, the immune system attacks and destroys the myelin sheath that surrounds and protects nerves cells. It's believed that SVF cells, and other stem cells, may limit this immune reaction and promote the growth ...

Stem Cell Breakthrough May Lead to MS Treatments

... into critical nervous system support cells called oligodendrocytes, according to a report released Thursday. Oligodendrocytes produce the myelin sheath that surrounds nerve fibers like wire insulation. The findings represent an important step toward embryonic stem cell-based therapies in general, ...

Mayo researchers discover mechanism of cell type-specific signaling in tumor development

... suppressor gene Merlin. When Merlin is absent or mutated, the result is schwannoma, a form of tumor involving Schwann cells which make up the myelin sheath that covers nerves. Merlin has also been shown to play a part in causing melanoma, mesothelioma and possibly colorectal cancers. The researchers ...

Avastin effective at delaying brain tumor progression in recurrent disease

... is no existing standard therapy. Oligodendrogliomas begin in brain cells called oligodendrocytes, which provide support around nerves by building a sheath of myelin and facilitating electrical nerve impulses. The relatively uncommon tumor affects about 2,000 persons annually in the U.S. Most are under ...

Dogs Help in Hunt for New Cancer Drugs

... treated a 13-year-old giant schnauzer named Haley with thyroid cancer and a 6-year-old Golden Retriever named Buddy with malignant peripheral nerve sheath tumor. Buddy's tumor shrank 40 percent after 10 months of daily treatment, he said. Haley's shrank by 77 percent. Bauer's group is now doing ...

Lab-grown nerves promote nerve regeneration after injury

... nervous system. The researchers suspect that the living nerve-tissue construct encourages the survival of the supporting cells left in the nerve sheath away from the injury site. These are cells that further guide regeneration and provide the overall structure of the nerve. "This may be a new way ...

Study gives more proof that intelligence is largely inherited

... than was previously thought. Genes appear to influence intelligence by determining how well nerve axons are encased in myelin the fatty sheath of "insulation" that coats our axons and allows for fast signaling bursts in our brains. The thicker the myelin, the faster the nerve impulses. ...

Hard to Treat Diseases (HTDS) Releases experimental results in the treatment of (MS) Multiple Sclerosis

... of the therapy: - The severity of clinical signs of disease was significantly reduced - The pathological changes in the myelin sheath (demyelination) were not detected - The reduction of mononuclear cell infiltrates, composed of T cells and ...

Vitamin A signals offer clues to treating autoimmunity

... nerve tissue in a mouse model of multiple sclerosis, the authors found. In the model, mice are immunized against myelin, which forms a protective sheath around nerves. Injecting the mice with zymosan at the same time as immunization reduced the damage to their nerves. ...

Research Brings New Hope to Multiple Sclerosis Patients

... the immune system to recover and fight the virus. Multiple sclerosis is a disease where the body's immune system attacks the protective sheath surrounding the nerves. Natalizumab suppresses the immune system to slow or halt the progression of the disease. However, if the patient contracts ...

Heavy marijuana use may damage developing brain in teens, young adults

... of water diffusion that we found among the young men with histories of marijuana use suggest damage or an arrest in development of the myelin sheath that surrounds brain cells," said Ashtari. Myelin provides a coating around brain cells similar to insulation covering an electrical wire. If myelin ...

Stem cells used to reverse paralysis in animals

... nerve cells remain intact. However, the surviving nerve cells may no longer carry messages because oligodendrocytes, which comprise the insulating sheath of the spinal cord, are lost. The regenerative mechanism discovered was activated when a lesion formed in the injured area. After a lesion formed ...

New Pathways Studied to Repair Nerves

... by researchers at the San Francisco-based biotechnology company Genentech looked at the growth-preventing mechanism built into myelin, the protective sheath that surrounds nerve cells. They have identified a previously unknown receptor for the growth-preventing molecules in myelin. Block that receptor, ...

Researchers identify mechanism, possible drug treatment for tumors in neurofibromatosis

... or mutant copy. Still, for many years the trigger for neurofibroma growth has been a mystery. Schwann cells, which form a protective sheath around nerve fibers, were a prime suspect. However, neurofibromas also contain nerve fibers themselves, connective tissue and mast cells, the latter ...

MS patients have higher spinal fluid levels of suspicious immune molecule

... a rare genetic disorder that involves a mutation in the gene for TREM-2. Among other symptoms, Nasu-Hakola causes loss of the same protective sheath around nerve cell branches that is damaged by MS. One place where the TREM-2 protein commonly appears is the macrophage, an immune cell that ...

Lipoabdominoplasty: A New Type of Tummy Tuck Gets Even Better

... internally is very important, but the technique is tricky on several levels. In order to tighten the muscles, one must put stitches in the fascia--a sheath of connective tissue that envelopes and supports the muscles. Traditional stitches can tear through the fascia if they are too big or tight. Making ...

Low-Fat Milk OK for Some Toddlers

... low either. One likely reason that nature provides a reasonable amount of fat in breast milk is that fat is vital to the development of the myelin sheath in the brain, said Condon-Meyers. "That's why we worry about children not receiving enough whole fat," she said. Whole milk contains between 3.5 ...

MS drug development agreement based on WEHI's medicinal chemistry

... could block a potassium channel called Kv1.3. This potassium channel selectively inhibits autoreactive T cells, such as those that attack the myelin sheath in people with MS. Dr Baell says, "Our research in this area had a rocky start, but when our first patents were published in 2003, Start-Up ...

Caffeine Could Stave Off Multiple Sclerosis

... about 400,000 Americans, according to the National Multiple Sclerosis Society. The T-cells from the body's immune system attack the myelin, the fatty sheath that normally protects the nerve fibers in the central nervous system. This, in turn, produces scar tissue and triggers the symptoms of MS, which can ...

Severe retinal hemorrhaging is linked to severe motor vehicle crashes

... seen in shaken baby syndrome. Two patients had no signs of retinal hemorrhaging, but nine of the ten patients were found to have optic nerve sheath hemorrhages, which are also commonly found in shaken babies. "Hemorrhages of this degree have rarely been reported in accidental trauma, even with ...

'HiCy' drug regimen reverses ms symptoms in selected patients

... approximately 400,000 people - predominantly women - in the United States, is believed to occur when the body's immune system attacks the insulating sheath that coats nerve cells, causing it to degenerate. Consequently, electrical signals that the cells use to communicate with the rest of the body become ...

Potential viral therapy weapon for difficult cancers is safe and effective in study

... to the recipient. Dr. Cripe and his colleagues addressed the neural toxicity question in part by injecting normal human liver, skin and nerve sheath cells grown in the laboratory with the rRp450 virus and with the normal wild-type HSV-1 virus. Over a 72-hour period, researchers noted a robust ...

Personality study shows risk of first depression episode late in life

... study. But even in older adulthood, these traits confer risk. Presumably something about aging helps take down the faade or destroys the protective sheath that has kept them from significant depression. The findings from the prospective study, the first of its kind, are published in the May issue of ...

Food as Medicine?

... about 400,000 Americans are affected, according to the National Multiple Sclerosis Society. In MS, the immune system attacks the myelin, the fatty sheath that protects the nerve fibers in the central nervous system. The myelin, as it is damaged, forms scar tissue that prevents or hinders nerve ...

Jefferson neuroscientists show anti-inflammation molecule helps fight MS-like disease

... cannot be sent through the nervous system. Dr. Rostamis team was trying to understand the mechanisms of how immune responses damage the myelin sheath and axons in the brain. They had previously observed that IL-27, a signaling molecule called a cytokine, could suppress IL-17, another cytokine, ...

Angiotech To Participate In The American Academy Of Ophthalmology (AAO) 2007 Annual Meeting

... is comprised of microsurgical guarded knives for use in ophthalmic surgery. Key features of the SharpGuard(TM) product line include: - Guarded sheath designed to eliminate or minimize sharps injuries - Sharpoint(TM) premium quality microsurgical blades manufactured by proprietary Infinite ...

Cholesterol-lowering drug linked to sleep disruptions

... and cross the blood brain barrier into the brain. The brain controls sleep, and many of the brains nerve cells are wrapped in a fatty insulating sheath called myelin. The results showed that simvastain use was associated with significantly worse sleep quality. A significantly greater number of ...

Imaging shows structural changes in mild traumatic brain injury

... damage (tearing of the axons that allow one neuron to communicate with another) in white matter versus abnormalities in the myelin (the protective sheath that, if damaged, can disrupt signals between the brain and other parts of the body.) If an axon is severed, the damage generally cannot be repaired. ...

Antibody Helps Repair MS Nerve Damage

... sclerosis. According to the U.S. team, a single low dose of a human antibody administered to laboratory mice repaired myelin, the protective sheath that covers nerves. Multiple sclerosis wreaks havoc with the nervous system by stripping away this outer covering. "This is an exciting first ...

New Imaging Technique may Help Detect Multiple Sclerosis Early

... real-time in live mice using the technique. Myelin is the fatty sheath coating the axons, or nerve cells, that insulate and aid in efficient nerve fibre conduction. In diseases such as multiple sclerosis, the myelin sheath has been found to degrade. The researchers insist that the ...