Selective in Medical News

InteKrin Therapeutics Announces INT131 Phase 2a Results at the 2009 American Diabetes Association Annual Meeting

... "These data are supportive of INT131 acting as a selective modulator of PPARgamma in T2DM patients," ... into the clinic is an exciting validation of the selective PPAR modulator design of the molecule," added Dr ... a next-generation, non-TZD insulin sensitizer and selective modulator of PPARgamma (SPPARM). INT131 belongs ...

Shire's INTUNIV (Guanfacine) extended release in children with ADHD and oppositional symptoms

... on INTUNIV (guanfacine) extended release, a selective alpha-2A-agonist, at a major psychiatric meeting. ... Once available, INTUNIV will be the first selective alpha-2A receptor agonist approved for the ... understood, preclinical research suggests this selective alpha-2A agonist strengthens working memory and ...

Presented Data Confirm That RAPAFLO(TM) (silodosin) Provides Rapid, Highly Effective, Symptom Relief for Benign Prostatic Hyperplasia (BPH) Patients

... - Uniquely selective Agent Offers Significant Improvement - ... treatment. RAPAFLO (TM) is a new, uniquely selective alpha blocker for the treatment of the signs and ... RAPAFLO (TM) is an effective, uniquely selective alpha-1 adrenergic receptor antagonist. RAPAFLO ...

Stunning finding: Compounds protect against cerebral palsy

... pharmaceutical companies so far have not: highly selective compounds that inhibit the enzyme found in brain ... until they had a few compounds that were very selective and very potent for the brain enzyme. ... enzyme. Silverman sent him several potent and selective compounds, and Poulos produced crystal structures ...

California Woman Receives Most Advanced, Non-Invasive Upper Extremity Prosthetic Solution: Bionic i-LIMB Hand and Innovative Interface System Increase Amputee's Functionality and Confidence

... - Touch Bionic's i-LIMB Hand and biodesigns' selective compression-stabilization interface. Amputee now ... bionic hand, coupled with the innovative selective compression-stabilization interface system ... by a specially trained artist. Alley's selective compression-stabilization system is a ...

EntreMed Teams with JSB-Partners to Expedite Partnering of its Aurora Kinase Program

... ) ENMD-2076 is a novel, orally-active, selective kinase inhibitor with potent activity against ... opportunities for our unique, orally-active, selective kinase inhibitor, ENMD-2076. The relationship ... a novel antimitotic agent, and ENMD-2076, a selective kinase inhibitor, are in Phase 1 studies in ...

Selective Insurance Group Announces Officer Appointments

... the following appointments by its subsidiary, selective Insurance Company of America ("Selective"): ... equity portfolio co-manager. Mr. Ferraro joined selective in July 2003 as a senior equity research analyst. ... president of flood operations. Mr. Butler joined selective in 1981 and has held a variety of ...

How embryonic stem cells develop into tissue-specific cells demonstrated

... the stem cells achieve their development through selective activation or selective repression of genes. The collaborative ... until the last minute -- prepared to engage in selective activation into specific cells -- holding in ...

Selective Insurance Group Announces Officer Appointments

... the following appointments by its subsidiary, selective Insurance Company of America ("Selective"): ... assistant controller. Ms. Hupka joined selective in September 2000 as a senior reinsurance ... lines product manager. Ms. Dickens-Hunter joined selective in February 2008. She came ...

Moving beyond tamoxifen: Drug discovery and the future of selective hormone receptor modulators

... the foundation for a new class of therapeutics selective estrogen receptor modulators that could treat or ... so-called designer estrogens. These drugs, called selective estrogen receptor modulators (SERMS), can have ... now being applied to develop new drugs that are selective male hormone receptor modulators that could be ...

Sunesis Pharmaceuticals' SNS-595 Shows Clinical Activity in Patients With Relapsed or Refractory Acute Leukemias; Data Presented in Oral Session at 49th Annual Meeting of the American Society of Hematology

... DNA and poisons topoisomerase II causing selective DNA damage, was administered on a weekly or twice ... to 7:00 p.m. "SNS-032 demonstrates potent and selective induction of apoptosis in primary CLL cells at ... with ovarian cancer. SNS-032, Sunesis' potent and selective inhibitor of CDKs 2, 7 and 9, is being evaluated ...

SGX Pharmaceuticals BCR-ABL Program to be Presented at the American Society of Hematology 49th Annual Meeting and Exposition

... by SGX can provide potent, selective inhibition of both wild type and major ... (also known as SGX70393) is a potent, selective orally-bioavailable inhibitor of ... to discover and optimize potent, selective and orally-bioavailable inhibitors of important ...

Selective Insurance Group Announces Officer Appointments

... N.J., Dec. 4 /PRNewswire-FirstCall/ -- selective Insurance Group, Inc. announced the following ... president and general counsel. Mr. Lanza joined selective in 2004 as senior vice president and general ... operations officer. Mr. Marchioni joined selective in 1998 as a government affairs specialist. In ...

Bionovo Describes a New Class of Therapeutic Compounds

... - Highly selective estrogen receptor beta agonists have promise for ... receptors on cancer formation by developing selective estrogen receptor beta drugs. The mechanism of action of MF101 as a selective estrogen receptor beta therapy may provide a ...

Abbott Researchers Target Neuronal Nicotinic Receptors for Treatment of Pain and Cognition

... Abbott researchers are currently developing selective NNR compounds, which act as agonists (drugs that ... have been at the forefront of identifying selective NNR agonists and have published more than 75 ... 2 NNR Agonist Program ABT-089 is a partial and selective NNR agonist, which targets the Alpha 4 Beta 2 NNR ...

Selective attention increases both gain and feature selectivity of the human auditory cortex

... open-access journal PLoS ONE, showing that selective attention increases both gain and feature ... of the literature explains the neural basis of selective attention by means of an increase in neural gain, ... of Kauram ki and colleagues suggest that auditory selective attention in humans cannot be explained by a gain ...

QuatRx Announces Further Positive Phase 3 Results For Ophena(TM) (Ospemifene Tablets) in Postmenopausal Vaginal Atrophy

... in clinical development and a preclinical program. Fispemifene is a new selective estrogen receptor antagonist that is in Phase 2 studies as an oral treatment for the symptoms of secondary hypogonadism in men. Sobetirome, a novel, selective thyroid receptor beta agonist, is in Phase 1 as a potential treatment for ...

World's First Deep Brain Stimulation Device Approved for Treatment of Psychiatric Condition in Europe

... as defined by a Y-BOCS score over 30, and who have tried at least three selective serotonin reuptake inhibitors (SSRIs) without treatment success, may be ... disorder (OCD) in adult patients who have failed at least three selective serotonin reuptake inhibitors (SSRIs). About Reclaim DBS Therapy ...

Amira Pharmaceuticals Announces Initial Positive Phase 1 Clinical Data for AM211, a Novel Product Candidate for the Treatment of Respiratory Diseases

... positive data from a Phase 1 clinical study of AM211, the company's oral selective antagonist of the DP2 (also known as CRTH2) receptor. The interim ... compared to exposures observed in safety species. While there are no DP2 selective antagonists approved for therapeutic use, there is a strong scientific ...

Maybe Men Aren't So Picky After All

... Women can be just as selective when choosing mates, study finds MONDAY, June 29 (HealthDay News) -- Women and men are equally selective when picking a mate, according to a U.S. study that challenges the belief ...

Aethlon Medical Releases Shareholder Letter to Discuss the Treatment of Hepatitis-C Virus (HCV)

... In HCV care, the Hemopurifier(R) inhibits viral replication through selective adsorption of circulating HCV and augments the immune response by removing ... requirement for two cartridges and multiple pumps with DFPP. The selective ability of the Hemopurifier(R) to capture targeted viruses and ...

China Nepstar Chain Drugstore Reports First Quarter 2009 Financial Results

... sectors and enhancing the store operation standards. Meanwhile, in selective areas where business is seriously impacted by the worsened economic ... of store performance by closing poorly performing stores, being more selective in acquiring new stores and slowing the pace of new store openings, which ...

Thumbs Up at ARVO for Diaton Tonometer - New Through Eyelid Glaucoma Test Clinical Study Presented, Results as Accurate as Gold Standard

... Eyes". "It works," says Dr. Mark Latina, the inventor of selective Laser Trabeculoplasty (SLT). Fort Lauderdale, ... he said. "It works," said Dr. Mark Latina the inventor of selective Laser Trabeculoplasty (SLT). "It gives you a reasonable ...

FDA Approves SAMSCA(TM) (tolvaptan), the First and Only Oral Vasopressin Antagonist to Treat Patients With Clinically Significant Hypervolemic and Euvolemic Hyponatremia

... Administration (FDA) has approved SAMSCA(TM) (tolvaptan) as the only oral selective vasopressin antagonist for the treatment of patients with clinically ... We are delighted that with the approval of SAMSCA, Otsuka will deliver a selective and corrective treatment for hyponatremia to patients and physicians in ...

Study Shows NeuroStar TMS Therapy(R) Improved Key Elements of Cognition in Patients with Major Depressive Disorder

... of global cognition (Mini Mental Status Examination), short-term (Buschke selective Reminding Test) and long-term memory (Autobiographical Memory ... only, there was a statistically significant improvement on the Buschke selective Reminding Test in the TMS responders compared to TMS non-responders for ...

AdvanDx Receives FDA 510(k) Clearance for GBS PNA FISH(R) for Rapid Detection of Group B Strep from Lim Broths

... process, vaginal and rectal swabs from pregnant women are inoculated into selective enrichment broth, e.g. Lim Broth, and incubate overnight to stimulate the ... anywhere from 3 to 4 days, and while Lim Broth is highly sensitive and selective for Group B Strep, the subsequent workup and phenotypic identification can ...

Forest Laboratories, Inc. and Cypress Bioscience, Inc. Announce Commercial Availability of Savella(TM)

... (Nasdaq: CYPB ) announced today that Savella(TM) (milnacipran HCl), a selective serotonin and norepinephrine dual reuptake inhibitor approved for the ... Cypress Bioscience. Important Safety Information Savella is a selective serotonin and norepinephrine reuptake inhibitor (SNRI), similar to some ...

New P.E. Drug Approved In Europe While Premature Ejaculation Cure Remains Out of Reach to American Men

... function and helps prolong orgasm. Dapoxetine is among a class of selective serotonin reuptake inhibitor (SSRI) drugs that include antidepressants ... without physician consultation through www.prematrol4men.com and selective U.S. retailers, Prematrol will soon be available in many European ...

Licorice compound offers new cancer prevention strategy

... with non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or with selective COX-2 inhibitors like Vioxx or Celebrex reduces the number and size of ... the enzyme produces effects specific to those tissues unlike NSAIDs, selective COX-2 inhibitors, and steroid treatments that can prevent cancer ...

Bionovo to Present at Wall Street Analyst Forum's 20th Annual Institutional Investor Conference

... in the journal Cancer Biology and Treatment , described the powerful and selective mechanism of action for BZL101 in cancer tumors. Another study was ... describing the structural elucidation of active estrogen receptor beta selective compounds from VG101, Bionovo's drug candidate for vaginal atrophy. This ...

Forest Laboratories, Inc. and Cypress Bioscience, Inc. Announce Revised Timing for Commercial Availability of Savella(TM)

... announced today that they expect to ship Savella(TM) (milnacipran HCl), a selective serotonin and norepinephrine reuptake inhibitor for the management of ... Cypress Bioscience. Important Safety Information Savella is a selective serotonin and norepinephrine inhibitor (SNRI), similar to some drugs ...

FDA Clears Cellectar's IND Application for Lead Drug Candidate

... that this compound will benefit individuals with cancer due to its selective retention and accumulation in malignant cells versus nonmalignant cells. ... products' unique mechanism of action is based on their accumulation and selective retention in malignant tumors and not in normal cells. The company's ...

Neurocrine Biosciences Reports Fourth Quarter and Year-End 2008 Results

... Neurocrine and GSK has identified multiple unique high affinity and selective antagonists for the CRF1 receptor that are currently in clinical ... of nerve impulses between neurons. The Company has identified a highly selective VMAT2 inhibitor that is effective in regulating the levels of dopamine ...

How natural oils can be hydrogenated without making unhealthy trans fats

... that, thanks to new advances in nanoscience, sophisticated and highly selective heterogeneous catalysts can be made by controlling their structures," he ... researchers also plan to improve on the synthetic techniques used to make selective catalysts. Nearly 80 percent of all chemical industrial processes use ...

Forest and Cypress Announce FDA Approval of Savella(TM) for the Management of Fibromyalgia

... (Nasdaq: CYPB ) today announced that Savella(TM) (milnacipran HCl), a selective serotonin and norepinephrine dual reuptake inhibitor, was approved by the ... the United States. Important Safety Information Savella is a selective serotonin and norepinephrine inhibitor (SNRI), similar to some drugs ...

Frost & Sullivan Recognizes Neotropix's Approach to the Treatment of Small Cell Lung Cancer and Neuroendocrine Cancers

... biomarkers: synaptophysin, CD56, or chromogranin A. "NTX-010 is extremely selective and potent for killing tumor cells. In addition, no normal human cell has ... side effects or dose limiting toxicities," observes Symank. "The highly selective and targeted nature of the product kills only the cancer cells, leaving ...

FASgen, Inc. Announces Research and License Agreement With Centocor, Inc.

... small molecule inhibitors of the fatty acid biosynthesis pathway via selective inhibition of Fatty Acid Synthase (FAS) for use in Oncology. The FASgen ... Johns Hopkins researchers to create new therapeutic products based on the selective inhibition of fatty acid biosynthesis. The Company has the exclusive ...

New Guidelines Issued for Management of IBS

... Tricyclic antidepressants as well as the antidepressants known as selective serotonin reuptake inhibitors (SSRIs) benefit a broad range of people with ... is evaluated. Psychological counseling may also provide some relief. selective C-2 chloride channel activators, notably lubiprostone (Amitiza), are ...

EntreMed Focuses on Development of ENMD-2076

... pharmaceutical company committed to developing primarily ENMD-2076, a selective angiogenic kinase inhibitor, for the treatment of cancer. ENMD-2076 is ... over-expressed in human cancers. In addition, ENMD-2076 is relatively selective for the Aurora A isoform in comparison to Aurora B. ENMD-2076 has shown ...

Lumenis(R) Introduces Four New Products & Delivery Devices at the 2008 American Academy of Ophthalmology Annual Meeting in Atlanta, Georgia USA

... multicolor photocoagulator, photodynamic therapy laser, the revolutionary selective Laser Trabeculoplasty (SLT) system and solid state multicolor laser." ... of YAG photodisruption capabilities along with the innovative selective Laser Trabeculoplasty (SLT) technology, which was developed and ...