Ribonucleic in Medical News

Study in Nature: MicroRNAs hold promise for treating diseases in blood vessels

... of microRNAs (miRNAs). These small, single-stranded molecules of ribonucleic acid (RNA), discovered in the Victor Ambros lab in 1993, fine-tune protein ... of deoxyribonucleic acids (DNA), they are copied into chains of messenger ribonucleic acids (mRNA) that are "read" by cellular machines that build proteins. ...

Researchers map how staph infections alter immune system

... and the adaptive system, whose memory cells are called into action to fight off subsequent infections. In this study, researchers extracted ribonucleic acid from a drop of blood and placed it on a special gene chip called a microarray, which probes the entire human genome to determine which genes are ...

UT Southwestern's Olson wins prestigious French award for heart research

... cause congenital heart disease, the most frequent form of birth defect. Most recently, Dr. Olson has turned his attention to distinctive forms of ribonucleic acid called microRNAs, chemical cousins of DNA, which are increasingly recognized to activate, turn off or fine-tune various functions in cells. ...

Frost & Sullivan Recognizes Neotropix's Approach to the Treatment of Small Cell Lung Cancer and Neuroendocrine Cancers

... neuroendocrine cancers. This state-of-the-art product aids cancer treatment by using a naturally occurring, replication-competent, single-stranded ribonucleic acid (RNA) virus. (Logo: http://www.newscom.com/cgi-bin/prnh/20081117/FSLOGO ) NTX-010's benefits include a convenient once-only dosing ...

Promoting the healing process after a heart attack

... disease are still the most common cause of death in Western industrialised nations. According to recent findings, small pieces of composed of ribonucleic acids (micro-RNAs) affect the synthesis of hundreds of proteins that play a role in these diseases. The aim is to discover new inhibitors for this ...

Discoverers of Small Regulatory RNAs and Cholesterol-Lowering Drugs to Receive Lasker Awards for Medical Research

... work launched new fields of scientific research that have fostered significant advances in the medical arena." The discovery of small regulatory ribonucleic acids (RNAs) by Victor Ambros, David Baulcombe, and Gary Ruvkun broke open an entire new field. Until that time, proteins, not RNAs, were thought to ...

Tiny molecule helps control blood-vessel development, UT Southwestern researchers find

... DALLAS Aug. 12, 2008 The development and repair of heart tissue and blood vessels is intimately tied to a tiny piece of ribonucleic acid (RNA) that is found nowhere else in the body, researchers at UT Southwestern Medical Center have found. Because of its specificity to the ...

New test for joint infection could spare some patients an unnecessary procedure

... infection thereby giving false positives. Tuan says this new problem led them to expand their PCR approach by testing for bacterial messenger ribonucleic acid (mRNA). "When bacteria are dying, their mRNA is one of the first things to go," he says. As a result, the researchers hypothesized that a good ...

Tiny RNA Molecules Control Breast Cancer's Spread

... to better prognosis, treatments, researchers say WEDNESDAY, Jan. 9 (HealthDay News) -- Researchers have zeroed in on a handful of tiny ribonucleic acid (RNA) molecules that seem to control whether or not breast cancer travels to the lung and bone. These "microRNAs" essentially serve as brakes ...

Small RNAs can prevent spread of breast cancer

... Howard Hughes Medical Institute researchers have identified small pieces of ribonucleic acid (RNA) that suppress the spread of breast cancer to the lungs and bone. The new research shows that the most invasive and aggressive human breast ...

Research suggests targeted treatment strategies for lupus

... die at an increased rate, said Mishra. This new study suggests both a possible mechanism and treatment. The study examined microRNAs, chains of ribonucleic acid that are involved in cell proliferation and cell death. The goal was to explore the possibility that aberrant expression of microRNAs is ...

Biomarker may be an early predictor of advanced breast cancer

... the immune system to help cells move and migrate. There are three forms of osteopontina, b and cwhich are formed by splicing, or cutting and pasting, ribonucleic acid (RNA) molecules to make variations of the original gene. Osteopontin-a is the normal form that helps with immune functions. Little is known ...

RNA Nanotechnology To Rescue Cancer Patients In Future

... are called nanoparticles, and are assembled from three short pieces of ribonucleic acid. The microscopic particles are designed in such a way that they ... where they are able to halt viral growth or cancer's progress. RNA or ribonucleic acid has immense promise as a therapeutic agent against cancer, and ...

Genetic Code That Helps Kill Colon Cancer Cells Identified

... uncanny ability to kill cells that are likely to become malignant because of damaged genes in their nuclei. MicroRNAs are small chains of ribonucleic acid (RNA), which stick to messenger RNAs, and prevent proteins from being made. Dr. Josh Mendell, Assiatant Professor in the ...

Master Switches Found for Adult Blood Stem Cells

... scientists located the control switches not at the gene level, but farther down the protein production line in more recently discovered forms of ribonucleic acid, or RNA. MicroRNA molecules, once thought to be cellular junk, are now known to switch off activity of the larger RNA strands which allow ...

Biomarkers Found Harmful For Human Lupus

... are a problem in human lupus,' said Mishra, an assistant professor of rheumatology. Mishra said microRNAs are a class of small chains of ribonucleic acid that have important regulatory functions in the body, particularly in suppressing genes (RNA serves as the template for translation of genes ...

Hotel Guests Often Leave Their Cold Behind

... overnight resulted in rhinovirus transfer to fingertips. Reverse transcription-polymerase chain reaction (RT-PCR) was used to detect rhinovirus ribonucleic acid (RNA). The RNA of rhinovirus is surrounded by proteins that help it bind to other cells. Without a host cell, the virus cannot replicate, making ...

The Dengue Virus Unplugged

... make more virus. Flaviviruses are so efficient at this task that they can churn out tens of thousands of copies of their genome--which is composed of ribonucleic acid, or RNA--within hours of infecting a cell. For dengue and other flaviviruses, the first step is to produce viral proteins, including an ...

Patent for Seminal RNAi innovation Cleared in Australia

... agreement, has granted approximately 50 non-exclusive licenses to companies using this invention. The patent covers a process by which ribonucleic acid (RNA), the cellular material responsible for the transmission of genetic information, can silence a targeted gene within a living cell. The ...

Researchers Discover Two Proteins Involved In Cellular Destruction Of HIV Virus

... of proteins XPB and XPD has lower levels of HIV provirus in their chromosomes. Before HIV enters the cell its genetic material is in the form of ribonucleic acid or RNA, which gets converted into cDNA once it enters the cell. The researchers at Ohio introduced mutations of the two proteins into cells and ...

Lung cancer molecular profile discovered by researchers.

... Institutes of Health have collaborated in the study. As the name suggests, micro or miRNAs are small segments of genetic material called ribonucleic acid, or RNA, and are thought to control gene ex-pression. Two miRNAs — has-mir-155 and has-let-7a-2 — have been identified that could be used ...

Early detection of alcohol abuse is better option for treatment

... always effective in detecting alcohol abuse. According to the research finding one such way to find out a suitable biomarkers may be getting the ribonucleic acid (RNA) from human blood and use microarray analysis that will reveal gene expressions that can be used as a biomarker. often people are not aware ...

Developing HIV fighter

... the genes that play a role in HIV infection, potentially showing a new way to combat the virus that causes AIDS. The team used short forms of RNA - ribonucleic acid - that turn off genes vital for the production of proteins used by the virus to enter and infect cells. RNA carries the blueprint for ...