Pancreatic in Medical News

Blood Type May Boost Pancreatic Cancer Risk

... type are associated with an increased risk of pancreatic cancer, according to U.S. researchers. They studied the genomes of more than 4,300 pancreatic cancer patients and more than 4,500 people ... A, B or AB are associated with increased risk of pancreatic cancer. Those with blood type O aren't at ...

Metformin May Lower Diabetics' Odds for Pancreatic Cancer

... the added benefit of lowering their odds for pancreatic cancer by 60 percent, a new study shows. But ... in the association between diabetes and pancreatic cancer," explained study lead author Donghui Li, ... "It's a very complicated association because pancreatic cancer can cause diabetes, while on the other ...

Pancreatic cancer risk decreased by one anti-diabetic therapy, increased by others

... metformin is associated with a reduced risk of pancreatic cancer in diabetics, according to a new study in ... a robust protective effect of metformin against pancreatic cancer in diabetes. Our major observations were ... than five years of use, had a reduced risk of pancreatic cancer compared to diabetics who had not taken ...

Smoking increases potential for metastatic pancreatic cancer

... smoking may increase the likelihood that pancreatic ductal adenocarcinoma will become metastatic, ... high levels of osteopontin have been reported in pancreatic ductal carcinoma (PDA). Dr. Arafat and her ... provide a unique potential target to control pancreatic cancer aggressiveness, especially in people who ...

Cell Discovery May Bring Science Closer to Diabetes Cure

... 'Sox17' gene could further pancreatic research, study suggests MONDAY, ... in guiding embryonic stem cells to become pancreatic beta cells, which scientists believe could be ... off in a mouse embryo instructs a cell to become pancreatic or biliary, now we'll see if that same gene, ...

New drug candidate prolongs the lives of pancreatic cancer patients

... Every year, 42,000 Americans are diagnosed with pancreatic cancer. Few live very long, and less than 5% are ... Salirasib has shown positive results against pancreatic cancer and recently passed Phase I/II clinical ... gemcitabine, the standard drug used to combat pancreatic cancer, almost doubled the life expectancy of ...

New role discovered for molecule important in development of the pancreas

... may be one step closer. A protein, whose role in pancreatic development has long been recognized, has been ... system. These cells ultimately give rise to pancreatic islet cells, which include beta cells. By ... Metabolism at Penn. Pdx1 is a key regulator of pancreatic development and adult beta-cell function. For ...

Solvay Pharmaceuticals, Inc. Announces Commercial Availability of CREON(R) (Pancrelipase) Delayed-Release Capsules

... on April 30, 2009, for the treatment of exocrine pancreatic insufficiency (EPI) due to cystic fibrosis (CF) or other conditions. CREON(R) is the first and only pancreatic enzyme product (PEP) to receive FDA approval ... take note. CREON(R) is the first "zero-overfill" pancreatic enzyme product, meaning that the capsules target ...

Dietary fat linked to pancreatic cancer

... products was associated with an increased risk of pancreatic cancer, according to a new study published online ... because research relating fat intake to pancreatic cancer was inconclusive. To examine the ... to track a variety of health outcomes, including pancreatic cancer. Men and women who consumed high ...

Eating Animal Fat May Lead to Pancreatic Cancer

... and dairy products can increase your risk for pancreatic cancer, researchers from the U.S. National Cancer Institute report. pancreatic cancer, which is usually fatal, is the ... "found an association between high fat intake and pancreatic cancer risk -- specifically, high fat from animal ...

Obesity While Young Boosts Pancreatic Cancer Risk

... or obese as a young adult increases the risk for pancreatic cancer, and obesity in middle age is linked with ... survival from the disease, a new study finds. pancreatic cancer is the fourth leading cause of ... that excess body weight is a risk factor for pancreatic cancer. "The stronger association of excess ...

Being overweight, obese during early adulthood associated with greater risk of pancreatic cancer

... are overweight or obese have an increased risk of pancreatic cancer, and being obese at an older age is ... a lower overall survival rate for patients with pancreatic cancer, according to a study in the June 24 issue of JAMA . pancreatic cancer is the fourth leading cause of ...

Adenoviral vector specifically targeted to EphA2 receptor in pancreatic cancer cells

... pancreatic cancer is a devastating disease with poor ... of the absence of adenoviral binding sites on pancreatic cancer cells such as the coxsackie and adenovirus ... promising option to improve adenoviral entry into pancreatic cancer cells and to enhance the efficacy of ...

Epeius Biotechnologies' Rexin-G Receives FDA Fast Track Designation for the Treatment of Pancreatic Cancer

... second-line treatment for advanced or metastatic pancreatic cancer. The FDA Fast Track program, like Priority ... nature of the unmet medical need, namely pancreatic cancer, and the potential of Rexin-G and its ... Triples Survival Time in Chemotherapy-Resistant pancreatic Cancer ," documenting survival benefits, without ...

Jefferson researchers identify critical marker of response to gemcitabine in pancreatic cancer

... improve the efficacy of gemcitabine at treating pancreatic cancer, according to a Priority Report in Cancer ... stress response protein found in the cytoplasm of pancreatic tumor cells. In certain experimental settings, pancreatic cancer cells that overexpressed HuR were up to ...

New Tests Spot Tough-to-Detect Cancers Sooner

... method for early confirmation of bile duct, pancreatic cancers,, WEDNESDAY, June 3 ... of cytology and FISH increased the bile duct and pancreatic cancer detection rate from 20 percent to 43 ... annually diagnose more than 35,000 cases of pancreatic cancer. More information The American ...

Mayo Clinic finds new pathology tests double sensitivity to detect bile duct and pancreatic cancers

... ROCHESTER, Minn. - pancreatic cancer and bile duct cancer are difficult to ... that double the ability to detect bile duct and pancreatic cancers, according to a Mayo Clinic study ... such as bile duct cancer (cholangiocarcinoma) and pancreatic cancer often present as strictures, or a ...

Phase 3 Trial Initiated to Evaluate Combination Therapy of Nexavar(R) and Tarceva(R) in Patients with Liver Cancer

... non-small cell lung cancer and first-line pancreatic cancer." About the Phase 3 Study The ... one of the critical growth factors in NSCLC and pancreatic cancers. Tarceva is indicated as a monotherapy ... use is not recommended in that setting. In pancreatic cancer, Tarceva is indicated in combination with ...

$18 million awarded to TGen and University of Pennsylvania for pancreatic cancer research

... (Penn) will receive $18 million to research pancreatic cancer, Stand Up to Cancer (SU2C) announced ... Cancer Center at Penn, are co-leaders of SU2C pancreatic cancer "Dream Team,'' which will lead a three-year investigation into new approaches to treating pancreatic cancer, the fourth leading cause of cancer death ...

A New Way to Get Chemo to Pancreatic Tumors

... and slightly extend the lives of mice with pancreatic cancer, potentially paving the way for more ... remain to be answered, Tuveson acknowledged. pancreatic tumors are among the most difficult types of ... Cornell Medical College in New York City. pancreatic cancer is resistant to chemotherapy and ...

Video: CREON(R) (Pancrelipase) Delayed-Release Capsules First and Only Pancreatic Enzyme Product to Receive FDA Approval Under New Guidelines

... for thousands of patients with exocrine pancreatic insufficiency due to cystic fibrosis or other ... Capsules for the treatment of exocrine pancreatic insufficiency (EPI) due to cystic fibrosis (CF) or other conditions. CREON(R) is the first and only pancreatic enzyme product (PEP) to receive FDA approval ...

Popular diabetes treatment could trigger pancreatitis, pancreatic cancer

... in some patients and a greater risk of pancreatic cancer in long-term users, UCLA researchers have ... as risk factors for pancreatitis and, with time, pancreatic cancer in humans. Januvia is marketed by Merck & ... effect that could over time increase the risk for pancreatic cancer would be a concern," said Dr. Peter ...

Type of connection procedure after pancreatic surgery influenced rate of pancreatic fistula

... the small intestine resulted in a lower rate of pancreatic fistula, according to researchers at the ... is a common treatment for benign and malignant pancreatic diseases. pancreatic fistula, a leakage ...

Charring Meat May Boost Risk of Pancreatic Cancer

... burned or charred meat may increase your risk of pancreatic cancer, a new study suggests. Researchers used ... Over the course of nine years, 208 developed pancreatic cancer. Meat-eaters who preferred their steak ... done were almost 60 percent more likely to get pancreatic cancer compared to those who ate steak less well ...

Mayo Clinic researchers formulate treatment combination lethal to pancreatic cancer cells

... targeted therapies packs a powerful punch to kill pancreatic cancer cells in the laboratory, Mayo Clinic ... to new treatment opportunities for patients with pancreatic cancer, which is extremely difficult to treat. ... destroying up to 65 percent of cultured pancreatic tumor cells. The finding is particularly ...

Science Makes Inroads Against Prostate, Other Cancers

... prostate tumors, and better drugs outwit brain, pancreatic malignancies SUNDAY, April 19 ... new ways to beat cancer. Brain, prostate, and pancreatic cancer are some of the specific targets of the ... Clinic in Rochester, Minn., looked at inhibiting pancreatic cancer at the cellular level with a combination ...

Research Takes Aim at Pancreatic Cancer

... News) -- An active receptor found in certain pancreatic cancers might offer hope for treatment of the often fatal disease. A third of human pancreatic cancers looked at by Johns Hopkins University ... in some lung cancers. When mice with this type of pancreatic cancer were given erlotinib, an EGFR-inhibitor ...

Can EUS elastography help distinguish benign from malignant tissue?

... benign and malignant lymph nodes and focal pancreatic masses based on the EUS appearance is difficult ... underwent EUS examination with assessment of a pancreatic mass or lymph node. Knowing that malignant ... to differentiate benign from malignant pancreatic lesions are 92.3% and 80.0%, respectively, ...

New Drug Being Tested for Pancreatic Cancer

... News) -- An experimental drug appeared to reduce pancreatic cancer growth in laboratory tests, according to ... in some growth factors, resulting in decreased pancreatic cell viability. The drug achieved an 80 percent ... show that AMG 479 is a clinical candidate for pancreatic cancer therapy, either alone or in combination ...

Experimental insulin-like growth factor receptor inhibitor reduced pancreatic cancer growth

... factors (IGF-1 and IGF-2) and appears to reduce pancreatic cancer cells in early testing, according to a ... the American Association for Cancer Research. pancreatic cancer is one of the deadliest cancers, and less ... a variety of experimental therapies to bring pancreatic cancer under control. At Amgen, Pedro J. Beltran, ...

Pancreatic Islets in Forefront of Diabetes Research

... TUESDAY, April 14 (HealthDay News) -- pancreatic islets, which are hormone-producing cells, are ... therapy involves the transplantation of pancreatic islets from a donated pancreas to a person with ... from the journal. "The importance of human pancreatic islets, clinically or for basic science research, ...

Fox Chase performs the world’s first successful ViKY robot-assisted surgery for pancreatic tumors

... on a 65-year-old man who was diagnosed with two pancreatic cysts, one of which is potentially cancerous. ... takes no floor space. Standard treatment for pancreatic cancer is surgery to remove the head or tail of the pancreas. When patients present with pancreatic cancer localized to the tail of the pancreas ...

Obesity Tied to Poor Pancreatic Cancer Surgery Outcomes

... WEDNESDAY, March 18 (HealthDay News) -- Obese pancreatic cancer patients are more likely than non-obese ... The researchers studied data from 285 pancreatic cancer patients who had surgery to remove some or ... higher than 35 and increased risk of death from pancreatic cancer. "Our findings extend these ...

NCCN Announces Updates to Pancreatic Adenocarcinoma Guidelines

... New updates to the NCCN Guidelines for pancreatic Adenocarcinoma were announced on March 12 at the ... on systemic therapy in all disease stages. pancreatic adenocarcinoma is the second most common cause of ... Clinical Practice Guidelines in Oncology(TM) for pancreatic Adenocarcinoma today at the NCCN 14th Annual ...

Study Links Blood Type and Pancreatic Cancer

... type O blood have a much lower risk of developing pancreatic cancer, a finding that might help explain the ... The study found that the chances of developing pancreatic cancer were greater for people with a blood type ... that raise or lower an individual's risk for pancreatic cancer are largely unknown," the study's lead ...

'Personalized' genome sequencing reveals coding error in gene for inherited pancreatic cancer

... Scientists at the Sol Goldman pancreatic Cancer Research Center at the Johns Hopkins ... on an individual with a hereditary form of pancreatic cancer to locate a mutation in a gene called ... the genetic error responsible for this patient's pancreatic cancer, our team has provided an excellent ...

Alcohol consumption may increase pancreatic cancer risk

... drinks per day could increase a person's risk of pancreatic cancer by about 22 percent, according to data ... identified 2,187 individuals diagnosed with pancreatic cancer during the study. "This is one of the ... ever to look at dietary factors in relation to pancreatic cancer risk," said Genkinger. If individuals ...

Georgetown researcher: 2 or more drinks a day may increase pancreatic cancer risk

... a day could increase their risk of developing pancreatic cancer, according to a study published in Cancer ... the association between drinking and the risk of pancreatic cancer, but most studies depended on a person's ... about the relationship between alcohol and pancreatic cancer because drinking is associated with the ...

U-M Researchers ID Gene Involved in Pancreatic Cancer

... a gene that is overexpressed in 90 percent of pancreatic cancers, the most deadly type of cancer. ... called ATDC, is on average 20 times higher in pancreatic cancer cells than in cells from a normal pancreas. What's more, the gene appears to make pancreatic cancer cells resistant to current therapies. ...

Optical techniques show continued promise in detecting pancreatic cancer

... to be effective in detecting the presence of pancreatic cancer through analysis of neighboring tissue in ... help raise the extremely low survival rate of pancreatic cancer patients by aiding early detection -- uses ... may lead to a method for early diagnosis. pancreatic cancer is among the most deadly forms of cancer, ...