Nodes in Medical News

Chicago team uses artificial intelligence to diagnose metastatic cancer

... to non-invasively probe the nearby lymph nodes -- tissues where cancer cells first migrate once ... But in the early stages of cancer, lymph nodes often appear completely normal even if the cancer ... with suspected breast cancer who all had lymph nodes that appeared normal in the ultrasound -- ...

Breast Cancer Patients May be Spared Additional Surgery

... whose breast cancer has spread to the lymph nodes may not need a radical lymph node surgery. ... women whose breast cancer spread to the lymph nodes indicates that women with microscopic lymph node ... may not need to have the rest of their lymph nodes removed. "The surgical community now ...

Educational initiatives improve quality of care delivery

... looked specifically at the number of lymph nodes that were surgically removed in colorectal cancer ... by clinical staff had on improving the number of nodes removed. Investigators on the study chose to ... research shows that the standard number of lymph nodes that should be removed during colorectal cancer ...

New technique may help detect potential breast cancer spread

... a molecule designed to home in on nearby lymph nodes is just as accurate as current techniques, but ... the presence or absence of cancer in lymph nodes is an important predictor of breast cancer ... treatment. But finding the right lymph nodes to test and a standardized method of doing so ...

Early Detection of Melanoma Plus Regular Skin Exams is Vital For Beating Disease

... dermatologic surgeon often tests the lymph nodes to determine if the cancer has spread. If the ... sentinel lymph node biopsy tests the first lymph nodes into which the melanoma drains. If the lymph nodes are free of cancer cells, then the melanoma is ...

Study links arm/hand swelling to number of lymph nodes removed during breast cancer surgery

... breast cancer survivors, the number of lymph nodes removed during surgery and the presence of cancer in the lymph nodes were the two factors most directly linked to the ... volume, the removal of more than five lymph nodes and the presence of cancer in the ...

Can EUS elastography help distinguish benign from malignant tissue?

... diagnosis between benign and malignant lymph nodes and focal pancreatic masses based on the EUS ... to differentiate benign from malignant lymph nodes was 91.8% and 82.5%, respectively, compared to ... benign from malignant pancreatic masses and lymph nodes with a high sensitivi-ty, specificity and ...

DiagnoCure announces first quarter 2009 results

... suggested that patients with GCC positive lymph nodes could be considered and treated as stage III ... independently from other factors, patients whose nodes were GCC positive were 4.7 times more likely to develop disease recurrence than those whose nodes were GCC negative. In fact, patients with GCC ...

New website empowers colorectal cancer patients when discussing critical treatment decisions - DiagnoCure launches www.mypersonalcancerdiagnosis.com

... or absence of the GCC marker in the lymph nodes that have been removed during the colorectal ... absence of colorectal cancer cells in the lymph nodes removed during the surgery. The test is a ... proprietary assay that detects in lymph nodes the expression or absence of expression of the ...

Biomarker predicts disease recurrence in colorectal cancer

... the presence of a biomarker in regional lymph nodes is an independent predictor of disease recurrence ... the presence of occult metastases in lymph nodes that may not have been identified by current ... metastasized, or spread, to the regional lymph nodes carries a worse prognosis and a higher risk for ...

Major study on DiagnoCure's GCC biomarker published in Jama

... parts of the body. When GCC is detected in lymph nodes removed during colorectal cancer surgery, it is ... with cancer cells in their regional lymph nodes carry a worse prognosis and a higher risk of recurrence; detecting GCC in the patient lymph nodes could be useful for identifying patients who ...

Gene Test May Help Predict Colon Cancer's Return

... A marker in lymph nodes points to more persistent tumors, scientists say ... tumor-suppressing receptor in the lymph nodes -- may better reveal the chance of metastatic ... in Philadelphia, doctors often biopsy the lymph nodes when trying to determine the prognosis of ...

Cancer patients who receive neoadjuvant therapy followed by mastectomy may not need radiation

... had four or more pathologically involved lymph nodes or lymphovascular invasion. Specifically ... with four or more pathologically involved lymph nodes after pre-surgery chemotherapy relapsed compared ... noted that patients with zero involved lymph nodes after receiving chemotherapy prior to surgery ...

New nano device detects immune system cell signaling

... system, which tend to concentrate in the lymph nodes spread throughout the body, function as ... in the body, they rapidly migrate to lymph nodes and have to find the appropriate T-cells to alert ... T-cells among millions of cells within the lymph nodes remains an immunological puzzle. Scientists ...

More Cancer Lymph Nodes Analyzed at Specialty Centers

... stomach or pancreatic cancer may have more lymph nodes examined for the spread of cancer if they're ... surgeries, says a U.S. study. If too few lymph nodes are examined for cancer cells, a patient's cancer ... "Patients undergoing surgery had more lymph nodes examined at NCCN-NCI hospitals than at community ...

Checking more lymph nodes linked to cancer patient survival

... found that cancer patients have more lymph nodes examined for the spread of their disease if they ... from the stomach or pancreas. If too few lymph nodes are examined for malignant cells, a patient's ... recommend evaluating at least 15 regional lymph nodes for gastric and pancreatic cancer, according to ...

LSUHSC inventor awarded patent for new procedure to detect cancer spread

... to rapidly identify "sentinel nodes;" the lymph nodes most likely to contain early metastasis from a ... dye around a cancer can identify sentinel nodes that receive lymphatic drainage from the tumor ... flows through lymph channels and then into lymph nodes where it often begins to multiply and grow. The ...

PET/CT scan could be valuable noninvasive tool for determining stages of ovarian cancer

... whether the cancer has spread to nearby lymph nodes without having to perform surgery, according to ... removing all of the lymph nodes for testing rather than sampling a small number ... than 98 percent accurate in scanning the lymph nodes of stage I and stage II ovarian cancer patients. ...

OHSU Cancer Institute researchers find many stomach cancer patients are not gertting best therapy

... have also recommended that at least 15 lymph nodes should be removed with gastric resection surgery. ... that only 35 percent of patients had at least 15 nodes removed to check for cancer. The number of lymph nodes removed, however, did not affect survival. ...

Newly diagnosed breast cancer patients benefit from use of USFNA of lymph nodes

... fine needle aspiration (USFNA) of the lymph nodes is a safe, useful, and minimally invasive ... The study consisted of USFNA of axillary lymph nodes in 224 breast cancer patients. The researchers ... If USFNA were limited only to axillary lymph nodes with a cortical thickness of 3 mm or more, USFNA ...

Breast Cancer Lymph Node Biopsy May Need Closer Look

... free of cancerous cells in their sentinel lymph nodes were actually not cancer-free, and that tiny ... was complete dissection of the axillary lymph nodes (those found under the armpit) followed by ... molecules. The following day, only those lymph nodes to which the tracer molecules migrated (the SLNs) ...

Test can reduce recurrence of breast cancer

... for cancer cells, the surgeon removes more nodes from the patient, but if it is negative, the ... them. Nearly 20 percent of women with negative nodes confirmed by a traditional biopsy end up having a ... in for another surgery to take out more lymph nodes that have likely harbored the breast cancer ....

Less Invasive Way to Stage Lung Cancer Shows Promise

... "If the cancer has already spread to the lymph nodes in the middle of chest, you can't cure it [with ... the gold standard although . . . there are some nodes that are hard to get this way." "Could this ... TBNA, detecting 69 percent of malignant lymph nodes versus 36 percent. The combination of EBUS-FNA ...

Researchers find less invasive, highly accurate methods

... into a patients esophagus to access lymph nodes in the back of the lungs while the other is placed into the trachea, or airway, to reach nodes at the front and sides, was 93 percent accurate in finding malignant lymph nodes in a group of 138 patients. This is substantially ...

2 microRNAs promote spread of tumor cells

... found that metastatic tumors removed from lymph nodes contained more miR-373 than the primary breast ... patients whose cancer had spread to their lymph nodes compared to patients whose tumors had not spread. ... Huang says. So if we detect miR-373 in lymph nodes when a patients breast tumor is removed, it would ...

Jefferson scientists find protein helps pancreatic cancer cells evade immune system and spread

... that the metastatic cancer cells in the lymph nodes of patients with pancreatic cancer produce enough ... cancer cells can survive in nearby lymph nodes is by avoiding the immune system. Evidence from ... pancreatic cancer cells residing in the lymph nodes expressed IDO to avoid being found, and if so, ...

Researchers train the immune system to deliver virus that destroys cancer in lab models

... found that once the T-cells returned to the lymph nodes and spleen, the virus detached itself from the ... the presence of melanoma tumor cells in lymph nodes was significantly less, but not completely gone. ... days after a T-cell transfer, both the lymph nodes and spleen were free of melanoma tumor cells. ...

Lymphatic vessel and lymph node function are restored with growth factor treatment

... The frequent spread of certain cancers to lymph nodes often necessitates surgery or radiation therapy ... factor-C (VEGF-C) to replace excised mouse lymph nodes and lymph vessels ensures formation of mature ... mice. The ability to transfer lymph nodes that reconstitute a functional network of ...

Hospital quality indicator may not be linked to patient survival after colon cancer surgery

... Examining a specific number of lymph nodes after colon cancer surgery, a measurement that ... among patients in whom a higher number of nodes are examined after colectomy for colon cancer ... of their patients in whom 12 or more lymph nodes were examined and then were sorted into four ...

Study Challenges Colon Cancer Surgery Follow-Up

... Routine testing of 12 lymph nodes may not be as useful as thought, researchers say ... wisdom of checking on the health of 12 lymph nodes after colon cancer surgery. These post-op ... . The routine examination of 12 lymph nodes after colon cancer surgery has been endorsed by ...

Black Women Get Less Breast Cancer Treatment

... with breast cancer that has spread to the lymph nodes are less likely to undergo supplemental, ... White women whose cancer had also spread to the nodes were nearly five times as likely as blacks to ... that women whose cancer had spread to the lymph nodes were more likely to receive supplemental ...

Less invasive lymph node biopsy method could spare thousands unnecessary operations

... an ultrasound-guided fine needle to biopsy lymph nodes could spare thousands of melanoma patients every ... so that 99 percent of patients with healthy lymph nodes were correctly classified. The study, the ... Whether cancer has spread to the lymph nodes is the most important factor influencing the ...

Genomic Health's Oncotype DX(R) Colon Cancer Test Predicts Individualized Recurrence Risk for Stage II Colon Cancer Patients

... repair (MMR), also known as MSI (Microsatellite Instability), T-stage, nodes examined, grade and lymphovascular invasion. These findings, which ... beyond other key variables including tumor stage, tumor grade, lymph nodes examined and MMR/MSI. The final set of seven recurrence, six ...

New minimally invasive surgery option for patients with stomach cancer

... retrieval, an important part of a complete cancer surgery in which nearby nodes are removed and then carefully examined for the presence of cancer cells ... an ongoing controversy that questions whether removal of the lymph nodes and other oncologic features of the resection during laparoscopic ...

UCSF Finds Potential New Antibody Treatment for Autoimmune Diseases

... revealed that the patient's CD4 T cells did not move out of her lymph nodes as they would in a normal immune system because her body created ... the signaling that triggers T-cell movement from the thymus and lymph nodes into blood and then into many organs. Researchers then explored ...

Previstage(TM) GCC to be presented at ASCO GI

... microscopically examine a thin slice of tissue from each of the lymph nodes harvested during the patient's surgery to see if cancer has spread. Currently, up to 30 percent of patients with no pathologically positive lymph nodes (stage I and II cancers) later develop recurrent disease, presumably ...

Molecular imaging enables earlier, individualized treatment of thyroid cancer

... time to accurately distinguish between cancerous cells in regional lymph nodes and normal residual thyroid tissue directly after surgery. Researchers ... demonstration or exclusion of cancer spread (metastasis) in regional lymph nodes plays a major role in treating the disease since all patients with lymph ...

Genomic Health Announces Study Establishing the Utility of Oncotype DX(R) in Node-Negative and Node-Positive Breast Cancer Patients Treated with Aromatase Inhibitors

... ATAC trial, including patients with disease that had spread to the lymph nodes (0 nodes, 1-3 nodes and more than 4 nodes). Researchers, with support from the UK's leading ...

Two Endometrial Cancer Treatments May Not Work

... two new studies show. One study looked at removal of pelvic lymph nodes (pelvic lymphadenectomy), in addition to the standard treatments of ... tubes (bilateral salpingo-oophorectomy -- BSO). Removal of pelvic lymph nodes is used to determine whether or not the cancer is present outside the ...

Highly specialized, minimally invasive surgery for lung cancer allows patient to go home sooner

... main goal which includes the removal of lymph nodes." Adjusted mean lymph nodes stations (#/patient) was 4.6 (open) versus 4.2 (VATS), p=0.249. Adjusted mean number of lymph nodes per patient was 18.1 (open) versus 14.7 (VATS), p=0.145. (Walter, the ...