Nephropathy in Medical News

Targeted drug therapy found effective in patients with common form of immune-mediated kidney disease

... be healed in some patients. Membranous nephropathy (also known as membranous glomerulopathy) is one ... colleagues treated 50 patients with membranous nephropathy with rituximab. The investigators found that 10 ... demonstration that kidney injury in membranous nephropathy can regress after selective depletion of B cells. ...

JCI online early table of contents: Jan. 2, 2008

... is prematurely sialylated in individuals with IgA nephropathy Among individuals with the relatively common ... from the peripheral blood of patients with IgA nephropathy and demonstrated that premature sialylation is ... IgA1-secreting cell lines from patients with IgA nephropathy produce aberrantly glycosylated IgA1 AUTHOR ...

Immunoglobulin Can Predict Some Diabetic Complications

... complications in people with type 1 diabetes who have diabetic nephropathy (DN) -- kidney damage caused by diabetes. The study included 139 ... The MedlinePlus Medical Encyclopedia has more about diabetic nephropathy . -- Robert Preidt ...

PLC Medical Systems Announces Publication of Care Study Update

... in Renally Impaired Patients (CARE) Study determined that Contrast-Induced nephropathy (CIN) is associated with long-term adverse events, ranging from pulmonary ... RenalGuard as a safe and effective prevention device for contrast induced nephropathy may not be completed in a timely fashion, if at all, or, if these clinical ...

New Test May Help Kidney Transplant Patients

... viral aggregates that form in the kidneys of people with polyomavirus nephropathy and are excreted in the urine. The researchers said the test takes ... of Nephrology . "An early and accurate diagnosis of polyomavirus nephropathy will result in a better understanding of the disease and ultimately ...

Halpin Foundation and the ASN announce recipient of Halpin Foundation-ASN research grant

... led to the creation of a fund to promote research relevant to membranous nephropathy in 2004. The Halpin Foundation dedicated itself to the study of this ... "Unfortunately, there are many unanswered questions surrounding membranous nephropathy and nephrotic syndrome, and we are grateful to The Halpin Foundation for ...

Late-breaking results of clinical trial on therapeutic endovascular cooling reported at TCT 2008

... Late-breaking results from the COOL RCN (COOLing to Prevent Radio Contrast nephropathy in Patients Undergoing Diagnostic or Interventional Catheterization) Trial ... exposure to intravascular contrast agents is known as radiocontrast nephropathy (RCN). Principal Investigator Gregg W. Stone, M.D., CRF Chairman, ...

Study: Before a CT scan or angiogram, many people should take inexpensive drug to protect kidneys

... go up when the kidneys arent operating efficiently. Contrast-induced nephropathy is defined as a 25 percent or greater increase in creatinine within 48 ... as a surrogate for kidney function. The problem of contrast-induced nephropathy is a relatively recent one a byproduct of the dramatic increase in the ...

PLC Systems Reports First Quarter 2009 Results

... clinical trial in Italy and the planned future U.S. clinical trial for RenalGuard as a safe and effective prevention device for contrast induced nephropathy may not be completed in a timely fashion, if at all, or, if these clinical trials are completed, they may not produce clinically significant or ...

PLC Systems Reports Fourth Quarter 2008 Results

... the EU launch and in raising additional funding for the U.S. clinical trial to investigate the efficacy of RenalGuard in preventing Contrast Induced nephropathy (CIN)." Mr. Tauscher added, "Our core TMR business in the U.S. continues to provide a base level of revenues, primarily through kit sales and ...

FDA Puts Black-Box Warning on Bowel-Cleansing Drugs

... now require a black-box warning on the oral sodium phosphate products Visicol and OsmoPrep, alerting consumers about the risk of acute phosphate nephropathy -- a type of severe kidney injury. "The FDA has received reports of 20 unique cases of kidney injury associated with the use of OsmoPrep," Dr. ...

Study compares strategies for BK virus nephropathy

... For kidney transplant recipients with a serious complication called BK virus-associated nephropathy (BKVAN), promptly cutting back on anti-rejection drugs reduces the risk of losing the kidney (graft loss), according to a report in the November ...

Battelle to Perform Verification Studies of IntelligentMDx's Proprietary Molecular Diagnostic Assay Process

... its performance characteristics. Financial terms of the agreement were not disclosed. BKV has recently emerged as an important pathogen in nephropathy in kidney transplant patients and hemorrhagic cystitis in human stem cell transplant patients. The IntelligentMDx Quantitative BK Virus Real-Time ...

The future of interventional cardiology presented at TCT 2008

... 9:30 A.M. COOL RCN: A Prospective Randomized Trial Examining the Safety and Efficacy of Systemic Hypothermia for the Prevention of Radiocontrast nephropathy ISAR-Left Main: A Randomized Comparison of Sirolimus-Eluting and Paclitaxel-Eluting Stents in Unprotected Left Main Coronary Artery Disease FAME: ...

TCT update: press conference schedule announced for TCT

... 9:30 A.M. COOL RCN: A Prospective Randomized Trial Examining the Safety and Efficacy of Systemic Hypothermia for the Prevention of Radiocontrast nephropathy ISAR-Left Main: A Randomized Comparison of Sirolimus-Eluting and Paclitaxel-Eluting Stents in Unprotected Left Main Coronary Artery Disease FAME: A ...

Newly found gene variants account for kidney diseases among African-Americans

... 222 who did not have FSGS and replicated these findings in additional cases. The Johns Hopkins researchers, members of the Family Investigation of nephropathy and Diabetes (FIND) consortium, studied more than 2,100 participants of the FIND study and the Choices for Healthy Outcomes in Caring for ESRD ...

PLC Systems Reports Second Quarter 2008 Results

... "As we recently announced, we have elected to defer the onset of our U.S. pivotal trial for RenalGuard(TM) for the prevention of Contrast-Induced nephropathy (CIN), but we are moving forward with our limited launch of RenalGuard in Italy as well as continuing our support of the investigator-sponsored ...

Gum Care Helps Control Type 2 Diabetes and Its Complications

... likely to develop worsened glycemic control; another showed that those with severe gum disease had more than triple the risk of dying from diabetic nephropathy or ischemic heart disease than those with less severe periodontal disease. A study, funded by the National Institutes of Health, that found a ...

Fatty liver linked to increased risk of diabetic kidney disease

... lead to end-stage renal disease (ESRD)permanent loss of kidney function requiring dialysis or transplantation. "The treatment of earlier stages of nephropathy in diabetes is effective in slowing the progression toward ESRD," Drs Targher and Chonchol note. "Thus the early detection of precursors and risk ...

Iso-osmolar X-ray dye falters in PCI study

... coronary artery disease, invasive procedures often require the use of elevated contrast volumes." In fact, although the risk of contrast-induced nephropathy (CIN) in patients with normal kidney function is very low (far below 1 percent), it is as high as 20 percent to 30 percent in patients with chronic ...

Novel discovery by Einstein scientists could lead to much-needed kidney failure treatment

... Collectively, the observations made in the Einstein study offer strong evidence that aberrant Notch signaling is also involved in diabetic nephropathy (DNP) and focal segmental glomerulosclerosis (FSGS)two of the major causes of end-stage renal disease. For example: When comparing biopsy samples ...

PLC Systems Receives CE Mark Approval for RenalGuard(TM)

... capabilities of the RenalGuard System in a cath lab setting during cardiovascular imaging procedures for patients at higher risk of Contrast-Induced nephropathy (CIN). PLC's President and Chief Executive Officer, Mark R. Tauscher, said, "Receiving the CE Mark for RenalGuard is an important milestone for PLC ...

Receptor protein appears to be key in breakdown of kidney filtration

... or small molecule compounds can prevent or decrease proteinuria in animals, which may represent a novel therapy for kidney diseases such as diabetic nephropathy and focal segmental glomerulosclerosis, adds Changli Wei, MD, PhD, first author of the article. The kidneys filtering activity takes place in ...

PLC Medical Systems to Display RenalGuard(TM) During Renal Week 2007

... of its RenalGuard System. Safety results were favorable, and there were no adverse renal events related to the device recorded. Contrast-Induced nephropathy Approximately seven million patients worldwide undergo interventional cardiovascular therapeutic and diagnostic imaging procedures each year. CIN is ...

Genentech/Roche's Lucentis and Eli Lilly's Ruboxistaurin Will Drive the Diabetic Retinopathy and Nephropathy Drug Markets

... treatment of diabetic retinopathy and diabetic nephropathy. The new Pharmacor report entitled Diabetic Complications: Retinopathy, Neuropathy, and nephropathy finds that, over the next decade, treatment of diabetic complications will expand considerably beyond tight control of blood pressure and glucose ...

Ruboxistaurin As A Novel Treatment For Diabetic Nephropathy

... upon established therapies for diabetic nephropathy//. nephropathy is known to develop in 40% of people with type 2 diabetes and is the ... world. Many persons with diabetes have progressive nephropathy even with the established therapies. Therefore, treatments targeting novel ...

India may See Outbreak of Cardiovascular Illnesses

... would have a population of around 57.2 million diabetics by the year 2025, many of whom would be adults of working age. In India diabetic nephropathy is expected to develop in 6.6 million of the 30 million patients suffering from diabetes. ...

Biocon Unveils Renal Therapies for Kidney Disorders

... in India than in the developed countries, with gloerulonephritis being the most common cause, accounting for one-third of patients, while diabetic nephropathy accounts for about one-fourth of patients. "In the absence of national registries, no reliable data is available on the incidence and prevalence ...

Recognition for 75 Years with Type 1 Diabetes!!

... of type 1 diabetes 57 years. The data collected so far show that individuals who have survived 50 years or more have a greatly reduced risk of nephropathy and retinopathy. Joslin Diabetes Center has awarded the 50-Year Medal to more than 2,400 people worldwide since 1970. The Award Program dates ...

Kidney diseases and their complications, an alarming scenario in the Philippines

... Philippine Society of Nephrology (PSN) issued the statement that diabetes is the single most common cause of kidney failure among diabetes mellitus nephropathy patients. Dr. Dinna Cruz, a kidney specialist trained at Yale University School of Medicine said that early detection prevents chronic ...

Breastfeeding To Reduce Risk Of Type 2 Diabetes

... ones include heart disease, diabetic retinopathy (damage to eyes, can lead to blindness), diabetic neuropathy (damage to nerves) and diabetic nephropathy (damage to kidney). In conclusion, more clinical studies are clearly indicated to better understand the physiological mechanisms behind the ...

Development of kidney disease in adults with pre-diabetes

... explain most of the increased odds of development of CKD seen among participants with IFG and newly diagnosed diabetes. Traditionally, diabetic nephropathy is thought to be a microvascular complication of diabetes, characterized by the classic Kimmelstiel-Wilson syndrome lesion. Data from this study ...

Nutrition Guide For Diabetic Nephropathy

... American Diabetes Association (ADA) in San Diego and reports from new research also presented at the June 10–14 meeting identified the most effective nephropathy screening and care management techniques for the primary care setting. Elizabeth Heubeck in DOC News this September, provides a nutrition guide for ...

Prohibited diet medicine found in Chinese herbs

... may be accidentally substituted for others (such as happened when Arisolochia was substituted for Stephania, leading to the outbreak of Chinese Herb nephropathy in Belgium), or may be in short supply and substituted or omitted from preparations. We need to ensure that the products sold have undergone the same ...

Premature Babies More Likely If Women Have Higher Protein Albumin In Urine

... Indication - proteinuria, preeclampsia, glomerularnephritis and diabetic nephropathy Physiology - Normally protein is present in only in trace levels in ... and multiple myeloma.Marked proteinuria-glomerularnephritis,diabetic nephropathy http://www.medindia.net/bloodtest/ biochemistry/Proteinuria.htm ...