Narcolepsy in Medical News

Researcher IDs Narcolepsy as Autoimmune Disease

... say they have determined that the sleep disorder narcolepsy is actually an autoimmune disease. The ... May 3 online issue of Nature Genetics , links narcolepsy to mutations of two genes involved in critical ... that narcoleptics have been found to lack. narcolepsy causes excessive drowsiness, to the point of the ...

Narcolepsy is an autoimmune disorder, Stanford researcher says

... confirming experts' long-held suspicion that narcolepsy is an autoimmune disease. The work, which will ... this story to a close and that we can use narcolepsy as a model for other diseases." narcolepsy affects about one in 2,000 people and is ...

Potential dangers faced by narcoleptics who use nicotine outlined in new abstract

... provides the first description of nicotine use by narcolepsy patients. Because people with narcolepsy can fall asleep suddenly and without warning, ... the excessive sleepiness brought on by their narcolepsy may also complicate any attempt by them to quit ...

Changes in narcoleptics' skin, core body temperatures affect their vigilance and sleepiness

... focused on eight patients who were diagnosed with narcolepsy with cataplexy and suffered from excessive ... when it was lowered, indicating that vigilance in narcolepsy can be altered simply by altering the temperature ... or warming their hands and feet. Patients with narcolepsy lack a specific neurotransmitter in their brains. ...

Lower metabolism, eating behavior possibly explain the cause of overweight in narcolepsy

... Paris, France, focused on 13 patients with narcolepsy and nine healthy controls matched for age, gender ... Only typical narcoleptic patients (those with narcolepsy with clear cataplexy and with suspected ... levels were twice as high in patients with narcolepsy as in controls. Narcoleptic patients had higher ...

Jazz Pharmaceuticals to Present Data From First Phase III Study of Sodium Oxybate in Patients With Fibromyalgia

... approved by the European Medical Evaluation Agency for the treatment of narcolepsy with cataplexy in adult patients. Most commonly reported adverse drug reactions in narcolepsy patients are dizziness, nausea and headaches. Sodium oxybate has the ...

Acupuncture Eases Side Effects of Head, Neck Cancer Treatments

... narcolepsy drug also helped with severe fatigue among patients on chemotherapy ... said. A second study presented Saturday at the meeting found the narcolepsy drug Provigil (modafinil) provided significant relief for patients ...

Addrenex Pharmaceuticals Announces Licensing Agreement With Dream Pharma

... ADHD) and ADX-415 (hypertension and menopausal flushing), Addrenex has two proprietary products in clinical development, ADX-N05 for the treatment of narcolepsy and ADX-117 for procedural sedation. For more information, visit www.addrenex.com ...

Treating sleep disorders in people with traumatic brain injury may not eliminate symptoms

... (35) were free of a sleep disorder, while 23 percent (13) had OSA, 7 percent (4) had periodic limb movements in sleep (PLMS), 5 percent (3) had narcolepsy without cataplexy and 3 percent (2) had post-traumatic hypersomnia. Participants underwent objective evaluation by overnight polysomnography to ...

Narcolepsy Drug Might Be Addictive

... comes as use of stimulant for enhanced mental function is on the increase TUESDAY, March 17 (HealthDay News) -- A drug used to treat narcolepsy is increasingly being taken to sharpen mental skills, but researchers now report troubling evidence that it also harbors the potential for abuse. ...

Publication Provides a Wake-Up Call For Clinicians Treating Narcolepsy

... MONTVALE, N.J., April 9 /PRNewswire/ -- narcolepsy remains underdiagnosed and undertreated even though this neurologic dysfunction is better understood and the available treatment options have ...

Jazz Pharmaceuticals, Inc. Announces LUVOX CR Launch Plans and Reports Development Pipeline Progress at Investor Day Presentation

... sales representatives currently promote XYREM(R) (sodium oxybate) for the treatment of excessive daytime sleepiness and cataplexy in patients with narcolepsy to sleep specialists, neurologists and psychiatrists. XYREM net sales increased by 34 percent, from $29 million in 2006 to $39 million in 2007. XYREM ...

Different Neural Pathways at Work Going Under, Coming Out of Anesthesia

... specialized neurons called orexins that regulate the body's wakeful state. They found that mice with damaged orexin systems -- similar to humans with narcolepsy -- took much longer to awake from general anesthesia than mice with normal orexin signaling systems. However, the mice with faulty orexin systems ...

Protein Nasal Spray Revives Sleep-Deprived Monkeys

... the researchers. The researchers suggested that these results could have important implications for people suffering from the sleep disorder narcolepsy and for people whose lifestyles may cause sleep deprivation, such as shift workers. The results were published in the Dec. 31 edition of The ...

Study: Modafinil is effective in treating excessive sleepiness

... adverse events. In modafinil-treated patients clinically significant increases in diastolic or systolic blood pressure were infrequent. In the narcolepsy studies one patient in the modafinil group and one in the placebo group had a clinically significant increase in heart rate. New clinically ...

Manufacturer to Pay $20 Million for Improperly Promoting a Sleep Disorder Drug

... one of its subsidiaries illegally marketed a narcolepsy drug for other unapproved uses. ... (FDA) for treating people suffering from narcolepsy only. But the settlement agreement signed ... can be distributed only under strict rules. The narcolepsy market in the United States is small, estimated ...

Narcolepsy May Be Caused By Environmental Exposures: Study

... diseases// characterized by selective cell loss, narcolepsy may be caused by environmental exposures before ... "The task of finding the etiology for narcolepsy will always depend on a partnership with the ... There does seem to be a genetic link to it. narcolepsy affects the same number of men and women. ...

UCLA Researchers Discover Link Between Parkinsons and Narcolepsy

... 2000, this same group of UCLA researchers first identified the cause of narcolepsy as a loss of hypocretin, thought to be important in regulating the sleep ... worldwide. (The percentage of those afflicted increases with age.) narcolepsy affects approximately one in 2,000 individuals about 150,000 in the ...

Cataplexy During Status Cataplecticus Resembles REM Sleep

... of// narcolepsy, which is a compulsive disorder to fall asleep. In narcolepsy there are compulsive sleep attacks and the person has an irresistible urge ... and Blood Institute estimated that nearly three out of four people with narcolepsy also have cataplexy, a major symptom of narcolepsy, which is characterized ...

Latest Research on Insomnia/Narcolepsy

... research shows promise for people suffering from insomnia, particularly narcolepsy - a chronic disorder by which people are unable to stay awake during ... of Health reported that there are more than 135,000 people who suffer with narcolepsy in the United States. So far there have not been any medications to help ...

Mystery of nacrolepsy uncovered

... of one of the most mysterious of medical conditions - narcolepsy. narcolepsy suffers fall asleep anywhere, at any time of day without warning. At other ... have identified a segment of DNA they believe is responsible for narcolepsy in a breakthrough being hailed as the first significant step forward in ...

Sleepwalking to sex during sleep, a new disorder detected

... sexual behaviours: Restless leg syndrome has caused several cases of masturbation or rhythmic pelvic movement while entering sleep. narcolepsy severe tiredness known to cause intense hallucinations of rape and sexual assault when patients do get to REM or dream stage sleep. Insomnia ...

$1.5 Million Grant to Yale for Narcolepsy-Neurotransmitter Study

... in narcolepsy. Narcolepsy is a neurodegenerative disease characterized by daytime sleepiness. The NIH grant will further Yale research into narcolepsy and other disorders linked to neurons that produce the peptide hypocretin. “The activity of these hypocretin cells is important for enhancing ...

Take A Walk To Boost Your Energy

... effect was greater than the improvement from using stimulant medications, including ones used for attention deficit hyperactivity disorder (ADHD) and narcolepsy - a chronic neurological disorder. The researchers said that nearly every group studied - from healthy adults to cancer patients, and those ...

Murky Relationships between Doctors and Pharmaceutical Companies Exposed

... last year from Jazz Pharmaceuticals through conducting seminars, delivering speeches, and visiting fellow doctors in their offices to promote the narcolepsy drug Xyrem. However what makes Dr Gleason’s case so peculiar is that he had been promoting Xyrem as a drug to be prescribed for depression and as a ...

Misdiagnosis of cataplexy

... cataplexy recognition will enhance the appropriate usage of sleep tests and eventually increase the timeliness and accuracy of the diagnosis of narcolepsy with cataplexy. ...

Brain mapping technique to explain sleep

... orexin that keeps the animal awake. Inhibitors of this protein will cause sleepiness, and in human beings, deficiency of this protein may lead to narcolepsy or sleeping sickness. Scientists of the study feel that how the orexin-producing neurons connect to other neurons, is the fact that will ...