lupus

New Way To Treat Lupus

Lupus can occur in several forms, but systemic lupus erythematosus (SLE)--usually referred to simply as... attacks the body's own tissue. New research into lupus suggests how the immune system goes awry in the disease//--a discovery scientists say could lead to ...

Control of inflammation

...ic of such disorders as asthma, chronic hepatitis, lupus and rheumatoid arthritis. Little is known about the body,s own mechanism for controlling inflammation and the tissue damage that accompanies it. According to Dr.Sitkovsky, there must be some way for the body to shout. The signal must be sensed and re...

Arthritis drugs are causing skin problems

...e vasculitis, psoriasis, dermatomyositis, systemic lupus erythematosus etc were also noticed. The researchers feel that there are sufficient data to conclude that TNF-á-blocking therapy for rheumatoid arthritis do cause dermatological problems of clinical importance. One of the reasons for such may be the...

High expression of interferon induces lupus disease

...hat will help in medical practitioners to diagnose lupus disease in their early state only for effective tr...e body’s own immune system. Patients affected with lupus may produce abnormal antibodies in their blood that may attack the body’s own tissues than outside i...

Identification of gene

...to distinguish self from non-self. In people with lupus and other autoimmune diseases such as arthritis, t... normal organs. While these cells appear normal in lupus sufferers, the victims’ tissues and organs still appear ravaged by an attacking immune system. Rese...

Researchers Find Out The Cause Of Immune Attacks Behind Hearing Loss

... people with systemic autoimmune disorders such as lupus or rheumatoid arthritis. Such people may be prone to losing all or part of their hearing due to an overzealous autoimmune reaction. All eight-study participants who had systemic autoimmune diseases showed signs of antibodies against IESCA. Six of the...

Oral contraceptives safe for women with Lupus erythematosus

... estrogens might provide benefit. Among women with lupus there is a high elective abortion rate – approaching 23 percent of pregnancies – which may reflect a failure of the birth control method used or the absence of an adequate birth control program." In the words of NIAMS Director Stephen I. Katz, M.D....

TNF Helps in the Understanding of the Immune System and Development of Drugs against Various Ills

...m-related ailments including septic shock, cancer, lupus and rheumatoid arthritis. The findings of the research were published in the journal Biological Chemistry. Andre Levchenko, a Johns Hopkins assistant professor of biomedical engineering and senior author of the paper said that cells are very sensitiv...

Epstein-Barr Virus May Be May Be A Cause For Multiple Sclerosis

...o other autoimmune diseases, particularly systemic lupus erythematosus (lupus), suggests that Epstein-Barr virus may have a broad role in predisposing to autoimmunity," or failure of the immune system to recognize the body's own tissues, the authors conclude. "A fine understanding of the mechanisms that co...

Autoimmune disorders studied in detail by U-M researchers.

...es effects of arthritis and the autoimmune disease lupus in mice and may be useful in treating psoriasis. Unlike conventional drugs for these conditions, which can’t discriminate between healthy and disease-causing cells, Bz-423 is highly selective, homing in on disease-causing cells. In an attempt to bet...

Knee Osteoarthritis May Be Triggered By Low Levels Of Estrogen

...m are present in rheumatoid arthritis and systemic lupus erythematosus, suggesting an association with symptoms, such as pain and inflammation, as opposed to disease onset and progression due to structural changes. The authors note that although the 2-hydroxyestrone levels in those with knee OA were signif...

Single Sugar Enables Antibody to Treat Inflammation

...matory autoantibodies in autoimmune diseases, like lupus and arthritis, less inflammatory. The next logical step then, Ravetch says, was determining how the IgG molecules in IVIG preparation could have an anti-inflammatory effect. Because a therapeutic, anti-inflammatory response to IVIG requires a conce...

Physical Activity and Weight Management, Checks Onset of Arthritis

...lts in the United States have got arthritis, gout, lupus or fibromyalgia, a rheumatic condition in which people experience pain. At this rate, the CDC feels that nearly 67 million US adults will be affected by 2030....

Biomarkers Found Harmful For Human Lupus

...ersity School of Medicine has found biomarkers for lupus that may play a role in causing the disease. //The...ences in the expression of micro-RNAs between five lupus patients and six healthy control patients who did not have lupus. 'We are the first to show that t...

Pregnant Women With Lupus Are At Greater Risk

...enter have found that pregnant women with systemic lupus are at higher risk for death and other medical com... study suggested that pregnant women with systemic lupus should be considered a high-risk population and should be monitored closely by both a rheumatologist...

Beta Agonists May Alter the Immune System

...sen diseases such as asthma // , heart failure and lupus that involve inflammation. The scientific team led by Raymond Penn, Ph.D., and Matthew Loza, Ph.D, found that beta-agonists, such as those used in the treatment of asthma, increase the accumulation of type 2 T cells, a type of white blood cell that ...

Understanding Autoimmune Disease

Cambridge: Type 1 diabetes, lupus and rheumatoid arthritis are autoimmune diseases, ...ciated with type 1 diabetes, rheumatoid arthritis, lupus and Graves' disease, but the gene had not been previously linked to regulatory T-cell function," say...

Kidney Disease In Children: Common but Treatable

...vush says. Systemic diseases such as diabetes or lupus put children at higher risk for kidney damage; they should be monitored regularly. Unrecognized kidney disease places people at greater risk for high blood pressure, heart disease and stroke. Researchers estimate that 650,000 Americans will develo...

Hope for Ending the Pain, Infertility of Endometriosis?

...autoimmune disorders such as rheumatoid arthritis, lupus and thyroid disorders. “Endometriosis, simply put, is when the lining of the uterus, or the womb, is located where it should not be: outside of the uterus,” says Dan Lebovic, M.D., M.A., assistant professor of obstetrics and gynecology at the Unive...

Infertility is Seen in Men With SLE

The prognosis for systemic lupus erythematosus (SLE), an autoimmune disease that mainly affects women in their reproductive years , has improved recently, prompting a shift toward improving quality of life. For men with SLE, concerns have been raised about their future fertility. ...

Rare Womens Lung Disease May Yield Insights Into Common Diseases

...men. LAM has a stronger female predisposition than lupus or breast cancer, and may have the strongest biological sex predisposition of any human disease, except for diseases of the genital organs, and it is often fatal. Scientists estimate that there could be as many as 250,000 LAM patients worldwide. LA...