hepatic

A new treatment for liver cancer

...e radioactive element yttrium into the femoral and hepatic arteries.// The beads travel to the liver and deliver the radiation there, killing cancer cells. The treatment has been found to work best with colorectal or gastrointestinal tumours, and less well with larger liver tumours or those involving the bil...

New target for antidiabetic agents identified

...ivity of Akt, a main target of insulin that blocks hepatic glucose output when glucose is available from food...increased glucose output from the liver. Elevated hepatic levels of TRB3 RNA and protein were identified in diabetic mice compared with wild-type mice, the au...

New Hope for Kidney Failure

... higher-than-normal levels of the natural molecule hepatic growth factor (HGF) or another natural factor called parathyroid hormone-related protein (PTHrP). Both groups of mice developed normal kidney functions, thus allowing the researchers to study how the high levels of HGF and PTHrP would affect kidney r...

Hope for Patients With Kidney Failure

... higher-than-normal levels of the natural molecule hepatic growth factor (HGF) or another natural factor called parathyroid hormone-related protein (PTHrP). Both groups of mice developed normal kidney functions, thus allowing the researchers to study how the high levels of HGF and PTHrP would affect kidney r...

FDA Approves New Drug For Asthma In Children

...topical effect to systematic activity in extensive hepatic metabolism. A maintenance treatment for asthma suffering children in the age group of 12 yrs and above, the drug may also be used for adult patients who require oral corticosteroids. These patients will require lesser doses of corticosteroids or stop...

Fat Cell Protein Hits Type-2 Diabetes

...ze, as happens in obese humans, might cause severe hepatic (liver) insulin resistance because less of a hormo...ose-derived hormone and then carefully measure the hepatic glucose production -- or action of insulin on the liver-- are we generating a significant effect?' T...

Study Unveils New Insight To The Madness Of King George III

...sted and fed liver. Moreover, they had showed that hepatic PCG-1 alpha is a major determinant of the severity of acute porphyric attacks in mouse models of chemical porphyria. The findings suggest that patients with porphyria should avoid any drugs or foods that turn on PGC-1 alpha activity in the liver, th...

Soy Protein Rich Diet May Help Fatty Liver Of Diabetics

... diabetes are often associated with fatty liver or hepatic steatosis, an untreatable condition that can lead to chronic liver disease and death. In this condition, large lipid-filled compartments accumulate in the cells of the liver due to an increase in production of fatty acids in it. The result is an en...

Higher incidence of bile duct injury during laparoscopic cholecystectomy

...r identification of the anatomical features of the hepatic pedicle was the most frequently reported cause (36.8%), and technical problems accounted for 27.0% of causes. The incidence of BDI was higher during cholecystitis (P One hundred eight BDIs (46.0%) were recognized intraoperatively and immediately re...

Glimepiride in the medical management of Type 2 diabetes

...ment, but they are often not sufficient to control hepatic glucose output and hyperglycemia. The author, Stephen N. Davis, stresses that it is important to treat patients to the established target values for blood glucose and A1C to achieve and maintain normal glucose physiology. Sulfonylureas are effect...

Obesity As A Contributor To Liver Disease

...modulate susceptibility to diet-related changes in hepatic NKT cells. These findings are important because th...olic fatty liver disease (NAFLD) is considered the hepatic manifestation of the metabolic syndrome, a cluster of metabolic abnormalities related to insulin res...

Hepatitis B Relapse In Cancer Chemotherapy Can Be Avoided By Antiviral Drug

... that preemptive antiviral therapy ameliorates the hepatic morbidity seen during transarterial chemotherapy and facilitates further chemotherapy without disruptions in the treatment schedules, the expectation would be for an increased chance of survival with this approach," the authors conclude. The study ...

Colon cancer patients benefit from Hepatic Arterial Infusion Therapy

... has spread to the liver fared better by receiving hepatic arterial infusion (HAI). In this technique chemoth... This study demonstrated the effectiveness of the hepatic arterial infusion therapy. It showed that it extended the survival and improved the quality of life ...

ROZEREM? Can Be A Better Option For Insomnia Patients

...ivity to any components of the formulation, severe hepatic impairment, or in combination with fluvoxamine. Failure of insomnia to remit after a reasonable period of time should be medically evaluated, as this may be the result of an unrecognized underlying medical disorder. Hypnotics should be administered w...

Coffee Drinking Associated with Lower Risk for Alcohol-Related Liver Disease

...s risk in alcohol consumers. Basic research about hepatic coffee-ethanol interactions is warranted, but we should keep in mind that coffee might represent only one of a number of potential cirrhosis risk modulators." Drinking coffee may be related to a reduced risk of developing the liver disease alcoholi...

India Approves Baraclude? (entecavir) For Treatment Of Chronic HEPATITIS B

...ppression is the key to reduction or prevention of hepatic injury and disease progression and the primary goal of treatment for chronic hepatitis B is to eliminate or permanently suppress the hepatitis B viral load. Viral load is a key predictor of progression to cirrhosis of the liver and hepatocellular c...

Intermittent Treatment Found Effective In Malaria

...e potential toxicity of treatment and the possible hepatic damage. After a temporary follow-up, specialists of the International Health Centre of Hospital Clínic de Barcelona compared contagion and mortality rates in both groups to assess the effectiveness of prophylaxis. The fact that the SP intermittent tr...

Arthritis Drug to Reverse Cirrhosis

..., it was revealed that Sulphasalazine prevents the hepatic myofibroblasts from generating the protein and thereby protects the scar tissue cells. It ultimately clears the scar tissue.The success in human trial would lead to Sulphasalazine treatment in end-stage patients replacing liver transplantation. ”...

Hepatitis B Drug Tyzeka Approved By FDA

...rom complications like liver cancer, cirrhosis and hepatic failure. The new drug gives doctors another option for treatment. A one year study of 1367 patients showed that telbivudine had a better response when compared to other drugs like lamivudine. Over a period of time however some participants develop...

Glucose Sensor That Controls Glucose Metabolism Identified

...ynthetic LXR activator) induced similar changes in hepatic gene expression, indicating that LXR functions as a glucose sensor in vivo that responds to increasing liver glucose uptake. The ability of the LXRs to respond to glucose and its derivatives was very specific: no effect was seen in other nuclear rece...

New Therapy to Treat Patients With Severely Elevated Cholesterol Levels

...s, and magnetic resonance imaging of the liver for hepatic fat content were performed throughout the study. A...n of liver transaminase levels and accumulation of hepatic fat in some but not all of the patients studied. Rader concluded, “Although our study establishes ...

New Cause of Chronic Liver Disease Identified in HIV-positive Patients

...f individuals who take anti-HIV therapy experience hepatic side-effects. The investigators note, however, that none of the classes of antiretroviral drugs have, to date, been associated with vascular liver disease. Yet, they also observe that all the patients had a history of therapy with ddI, which an earli...

Hepatic Stellate Cells Found Capable of Tissue Repair

...y which cells associated with liver damage, called hepatic stellate cells (HSCs), are activated by a cell sur... of HSC, which stimulates the proliferation of new hepatic cells to replace those that have been damaged. The effects of p75NTR at late stages of HSC activatio...

Multiple Sclerosis Patients to Benefit With AVONEX(R) Nurse Services Program

...ed. Patients should also be monitored for signs of hepatic injury. Routine periodic blood chemistry and hematology tests are recommended during treatment with AVONEX. Rare cases of anaphylaxis have been reported Source-IANS/N...

Inherited Genes Linked to Toxicity of Leukemia Therapy

...ic polymorphisms and gastrointestinal, infectious, hepatic (liver), and neurologic toxicities during each phase of treatment. The three treatment phases were induction, the initial phase designed to cause remission of the cancer; consolidation, the follow-up after induction; and consolidation, the final phas...

CE-US a Reliable Option to Diagnose Aftermath of Liver Transplant Complications

...as several causes, such as anastomotic strictures, hepatic artery thrombosis, non-anastomotic strictures, seg... in 43.5% of patients. Five transplants (13 %) had hepatic artery thrombosis or significant stenosis, and seven transplants (18 %) developed portal vein stenos...

New Cancer Fighting Virus

...mpressive in this patient, Dr. Mescheder said. The hepatic masses almost disappeared.The patient survived for 12 months after treatment. In the current study, the scientists are testing the treatment in patients with colorectal cancer that have not responded to chemotherapy and where the cancer has spread ...