Glycogen in Medical News

Glucose metabolism and recidivism of severe violent crimes in alcohol intoxications

... crimes. A Finnish study now finds that low glycogen level which means non-oxidative glucose ... deviations lower than non-recidivistic offenders. glycogen levels did not differ among nonrecidivists and 40 ... in alcohol intoxications when they have very low glycogen stores in the liver. The low activity of the ...

Gene therapy could save kids from a lifetime of eating cornstarch

... People born with the disorder, called glycogen storage disease type Ia (GSD-Ia), cant make an ... Fund for GSD Research, the Association for glycogen Storage Disease and the Duke Childrens Miracle ... dogs with a naturally-occurring canine form of glycogen storage disease. The original genetic carrier, a ...

Hydration Will Be Key For Beijing Bound Olympians, What Every Athlete Must Know

... For two hours after severe exercise, the ingested sugar is moved back into glycogen without insulin. By having more concentrated sugar concentrations in the drink, the glycogen restoration is helped. Athletes should pay close attention to the ...

Austin Company Makes a Splash at U.S. Olympic Team Swimming Trials

... minutes of completing a workout to speed the storage of muscle and liver glycogen and promote muscle tissue repair. "When you exercise," says Ivy, "the ... minutes of completing a workout to speed the storage of muscle and liver glycogen and promote muscle tissue repair. Among the athletes and coaches who ...

BioMarin Announces Second Quarter 2009 Financial Results

... is a highly phosphorylated GAA enzyme, which the company believes could result in more efficient uptake in cells and potentially lead to improved glycogen reduction in key affected muscle groups not addressed with current therapy. BioMarin continues to explore partnering options for this program. ...

Transplanted liver cells function in older animals but do not proliferate as much as in younger ones

... that seen in younger ones. Furthermore, found the scientists, the transplanted cells worked equally well in the old and young animals, as measured by glycogen storage, but the younger animals had significantly higher levels of a growth factor needed for proliferation. The new study is the first to offer ...

Scientists Gain Insight Into Blood Cancer's Progression

... into a deadlier stage. The finding may improve patient outcomes, they said. The researchers found that when a molecular off-switch called glycogen synthase kinase (GSK) 3 beta becomes faulty in chronic stage CML cells, it fails to turn off another protein called beta-catenin. This enables ...

Scientists uncover indicator that warns leukemia is progressing to more dangerous form

... and Regenerative Medicine Institute at the Stanford University School of Medicine, the researchers discovered that when a molecular off-switch called glycogen synthase kinase (GSK) 3 beta becomes faulty in chronic stage CML cells, it fails to turn off another protein, beta-catenin. This in turn enables ...

SoLo's Olympic Success Fuels NBA Preseason

... low glycemic profile delivers energy slowly, allowing athletes to perform at their best for extended periods of time, with the goal of sparing glycogen stores in the process. Athletes can trust that SoLo Bars will keep them powered for longer - to get through an endurance event, training run, or ...

New leukemia signal could point way to better treatment, Stanford researchers find

... form of leukemia. Their discovery hinges on a novel "double agent" role for a molecular signal that regulates cell growth. The rogue signal, glycogen synthase kinase 3, was previously found to halt uncontrolled cell growth, preventing several forms of cancer. It also keeps growth of healthy cells ...

Possible genetic predictor for response to lithium augmentation in depressed patients

... medication used to treat bipolar disorder. They then genotyped these patients for variations in the GSK3B gene. This gene codes for the enzyme glycogen synthase kinase 3-beta, which is inhibited by lithium. Mazda Adli, M.D., corresponding author on the project, explains their findings: [We] found ...

Genetic 'roadblock' hoped to inspire future type 2 diabetes research

... from the Samuel Lunenfeld Research Institute of Mount Sinai Hospital found the first genetic evidence that the elimination of the gene for glycogen synthase kinase-3 (GSK-3) in mice sensitizes the animals to insulin. Insulin is a hormone that helps control sugar (glucose) levels in the ....

A chocolate cookie a day puts 20 pounds on an energetically-balanced kid in 4 years

... nutrient deficiency whose consequences are serious health problems. In addition to this, miracle diets only help to lose weight in the form of glycogen and water not fat ? that being the reason why rapidly lost pounds are immediately recovered. Among those panacea diets, and absolutely ignoring all ...

Cooling Temperatures Help Crucian Carp

... to a goldfish, is able to store vast amounts of glycogen in its brain, due to the cooling temperatures ... study from Finland found that the amount of glycogen in the brain was at its peak in February, when ... 15 times higher in February, compared to brain glycogen content in July, when oxygen in the pond is at ...

Study Finds Abdominal Fat Not the Prime Cause for Metabolic Syndrome

... took the energy from carbohydrate in the meals and stored it away as glycogen in both liver and muscle," Shulman said. "In contrast to the ... the young, lean, insulin-resistant subjects had a marked defect in muscle glycogen synthesis and diverted much more of their ingested carbohydrate into liver ...

New DNA Tests Advances Treatment of Lysosomal Storage Diseases

... MPS I (Hurler, Hurler-Scheie, or Scheie syndrome). ERT also is in development for other lysosomal storage conditions including Pompe (also known as glycogen storage disease type II), MPS II (Hunter syndrome), Niemann-Pick Disease, and MPS IV (Morquio syndrome). ...

UIC Researchers Receive $2.1 Million Grant

... side effects, including weight gain." Efforts to understand the molecular target for lithium have shown that compounds that inhibit the enzyme glycogen synthase kinase-3 may mimic the therapeutic action of the mood stabilizers, Kozikowski said, and might point the way to the design of improved drugs ...

Dartmouth researchers zero-in on a gene that heightens muscle performance

... directly to a muscle's ability to repetitively contract during exercise. The activated AMPK in the Dartmouth mouse appears to have increased glycogen content by actually switching on a gene that normally synthesizes liver glycogen. "The switching on of this liver gene in muscles," he says, ...

World’s First Pediatric Laparoscopic Liver Surger

... helps metabolize food and medicine absorbed from the intestines in the blood supply, produces bile to help digest fats, and stores energy-producing glycogen (sugar). Primary liver cancer--which grows from within the organ as opposed to spreading there from another area of the body--is rare. In ...

Gene Therapy Technique for Inherited Heart Problems in The Pipeline

... that normally breaks down the carbohydrate glycogen, used to store energy. The disease causes gradual weakening of muscle and heart tissue when glycogen accumulates in muscles, limiting their ability to contract. ‘This is a way of delivering gene therapy to the heart that is aimed at treating ...

Chocolate milk may Be Good For Athletes

... the muscles. The findings suggest that chocolate milk has an optimal ratio of carbohydrates to protein to help refuel tired muscles To maximise glycogen replacement, sportsmen use to take a serving of carbohydrates within 30 minutes after a long and vigorous workout. Common sports drinks such as ...

A new recovery for heart attacks

... They also reduce the body's reliance on oxygen by switching to a form of energy production not dependent on oxygen, called glycolysis (which uses glycogen from the liver). Previous research has found that a protein known as Hypoxia Inducible Factor (HIF) responds to low oxygen levels and switches ...