fusion

Arthroscopy for Ankles

...kle surgery. One of the benefits of arthroscopy is fusion surgery, used as a last resort to relieve persiste...tra says arthroscopy improves the success of ankle fusion surgery compared to traditional surgery. New technologies such as electrothermal and laser probes ...

A question on study of Adult Stem Cell

...ed in recent research, may arise from a process of fusion that combines two cells into one, and not from one..."It should be noted that although spontaneous cell fusion has been well documented and this work has been overlooked in the recent reports on tissue stem cell...

Artificial discs available as replacements for damaged discs

...ials patients// were randomized, with one having a fusion operation for every two that received the artifici... get caught between degenerating components. While fusion may relieve the pain, it prevents natural, independent motion. The artificial disc being studied wo...

Mutant sperm beat out healthy brethren in study

...ert syndrome is marked by webbed fingers and early fusion of the skull bones, which must be surgically corrected. Researchers were looking for two mutations that cause virtually all cases of Apert syndrome."For some reason, a sperm with one of these mutations is more likely to be used to make a baby than n...

Another Cause of Thyroid Cancer Discovered

...the AKAP9 gene and the BRAF gene are involved. The fusion of these genes results in BRAF signaling normal cells to transform into malignant cells. This is a new discovery of cause for patients with thyroid tumors. Researchers conclude saying the discovery of the chromosomal rearrangement is remarkable and ...

The Use of Radio Frequency Identification ( RFID) to tackle the growing menace of counterfeit drugs

...tically variable pigments, magnetic inks, UV inks, fusion screens, encryption, 2 D barcode, water marks, security thread and laser printing. However they also say that instead of relying on RFID alone perhaps using a combination of various technologies would be ideal in India. Factors that encourage count...

Gene Fusion Test to screen children’s with Acute Lymphoblastic Leukemi

...ised treatment options. The gene test detects gene fusion of gene etv6 with runx1, bcr joining with abl and ...n 1,000 children’s with ALL were screened for gene fusion and found the pattern and type of gene fusion predicted the severity and prognosis to treatment. Chi...

The potent anti-leukemia activity of Berbamine

...n tyrosine kinase, which is encoded by the bcr?abl fusion gene, has been shown to be responsible for the malignant phenotypes. Gleevec, which is an inhibitor of the bcr/abl tyrosine kinase, has been a remarkable success for the treatment of CML. However, a significant proportion of patients chronically tr...

A Possible Cause Of Prostate Cancer Discovered

...tate cancer tissue samples they analyzed. The gene fusion was not found in non-cancerous prostate tissue. Id... development of a drug designed to target the gene fusion that causes leukemia. Medindia on prostate cancer: As the name suggests, prostate cancer develo...

Patients More Willing To Use Self-Injectable HIV Therapy Than Anticipated

...es to FUZEON (enfuvirtide), the first approved HIV fusion inhibitor, and an important option for treatment-experienced patients who face HIV resistance. FUZEON presents unique challenges because it is the first self-injectable antiretroviral whereas all other treatments are oral. It was found that 76% of ...

Chromosome Ends Trigger DNA Damage Response For Telomere Protection

...d chromosomes apart. The researchers assert that fusion breakage cycles scramble the genome over time, and cause genome instability, which is a hallmark of cancer cells, and this demonstrates the importance of telomeres in preserving genome integrity and preventing cancer development....

Exposure to hazardous tissue, a fear of 21 Windsor surgery patients

...ne if she has cause for alarm stemming from spinal fusion surgery in late 2004. "She is fearful and worried.” Were her exact words. Patients are being consoled yet the hospital has no clue of the infections that could be caused. Health Canada expressed concern over the fact that why did the authorities wa...

Inactivation of Rad9 in Tumor Cells Would Be Advantageous In Cancer Therapy

... of chromosomes which protects the chromosome from fusion or degradation. Rad9 proteins interact with prot... in damaging the chromosomes and caused end-to-end fusion at telomeres. This disrupted the cell cycle and caused cell death. Because radiation treatments in...

Switching Off Protein Could Play Key Role In Success Of Radiation Therapy For Cancer

...d at the ends of chromosomes and protect them from fusion or degradation. "We saw that Rad9 stabilizes telomeres, and because we aren't yet sure how it does it, we will continue to study how Rad9 influences the telomere structure," Pandita said. "We speculate that without Rad9, some of the other proteins as...

HIV Infected Body Parts Stolen: Biomedical Tissue Services To Face Legal Action

...believed to have contracted HIV following cervical fusion surgery (bone graft implantation into the neck) that had taken place last March at Sacred Heart Hospital, Pensacola. The New York based company is said to have skipped routine screening, and sent the unscreened body parts to another company, Regene...

Thailand to Explore Stem Cell Technology for Treatment of Heart Disease

...ill target 40 heart patients. This study will be a fusion of efforts from the Department of Medical Sciences, Mahidol University and the Cardiac Institute of Thailand. The test will be completed in a 2 month time frame. Despite the completion of the experiment in 2 months, yet it will take the teams at l...

Three-Dimensional Image Of AIDS Virus – BY FSU Researcher

... the target cell. Its stalk is responsible for the fusion event in which HIV injects its genes into the human host cells for which the virus has a natural affinity –- T lymphocytes and macrophages. ‘Antibodies that effectively bind to either of these spike parts will neutralize the virus to prevent infec...

Footwear The Hot Pick Of Summer Fashion In The West

...up to $300. 'I think it's a case of Indo-Western fusion kicking it off and actually making a statement with yuppies and even the fashion conscious,' says Thanga. It's obviously a case of Indian practicality meeting Western street chic! If your feet can look 15 even though your face looks 50, its time for ...

Humans, A Symbiotic Organisms Dependent On Other Life Forms For Existence

...teria and human cells, they felt we were somehow a fusion of human cells and bacteria. He also said that here are reports that 90% of the cells of our body were actually bacteria’s. He went on to explain that humans were entirely dependent on the population of these microbial organisms for their existence. ...

Differently Wired and Gay – Are They Children of a Lesser God

...e. Elaborating on the sentiment that marriage is a fusion of two minds, Gay activists assert that it is gross injustice to encourage marriages based on societal norms alone. Ultimately marriages that betray mutual attraction, might just fall apart, and contribute to higher divorce rates, they aver. And less...

Cure Insight for DMD

...cle eventually produce the protein produced by the fusion of the donor cells. The results are published in the latest issue of the Journal of Neuropathology and Experimental Neurology. Dr. Tremblay's team is the first in the world to achieve this level of dystrophin expression in so many patients, and in su...

Scientists Uncover The Secret Behind The Speed In Nerve cells Conduction

...Schaub was able to show that SNARE-driven membrane fusion – the act that opens the door for neurotransmitter...l cell – was inhibited by complexin. "By halting fusion partway, complexin essentially shortens the response time for signal transmission," said Schaub, who...

Gene Responsible For Mammary Gland Function, When Mutated Results in Leukemias

...ncontrollably. The leukemia mutation caused by the fusion of MKL1 to the gene RBM15 forms the RBM15-MKL1 fusion gene. AMKL resulting from this mutation usually has only a 20 to 25 percent survival rate. 'MKL1 is ...

NICE supports application of advanced biological therapies as treatment option for acute psoriasis

...binant human tumour necrosis factor (TNF) receptor fusion protein that inhibits the activity of TNF. TNF is a cytokine that is released from T lymphocytes; it mediates inflammation and modulates the cellular immune response. Enbrel is also indicated for treatment of the following: Severe, active and prog...

Only A Few Differentiating Factors Between Adult And Stem Cells

...ents into egg cell precursors called oocytes or by fusion with embryonic stem cells, earlier studies showed. Those findings provided evidence that unfertilized eggs and embryonic stem cells contain factors that can confer pluripotency to differentiated cells, Yamanaka said. "We hypothesized that the fac...

Latest Enhancements to the Free Access Grid Toolkit Now Available

... scientists and experimental facilities working on fusion power, to providing doctors and specialists with the ability to examine patient scans simultaneously at multiple sites, enriching diagnostics and biomedical applications. The Access Grid Toolkit includes Virtual Venues software and Workspace Dockin...

Study Findings Could Help In Developing A Better Drug Delivery System

...ong microtubules, hollow tube like structures, and fusion with special digestive-enzyme containing compartments within the cell called lysosomes. However, the research showed that disulfide reduction occurred even when such components were removed from the process. By inactivating different cellular compo...

Yet Another Reason not to Smoke

...h healing of bone fractures and also inhibits bone fusion processes -- many spine surgeons, for example, won't do certain operations on people who smoke because of the risk of failure. But little is known about the effects of cigarettes on tendon and ligament healing. There also are some gaps in medical kn...

Cigarette Smoking Impedes Tendon-to-Bone Healing

...h healing of bone fractures and also inhibits bone fusion processes — many spine surgeons, for example, won't do certain operations on people who smoke because of the risk of failure. But little is known about the effects of cigarettes on tendon and ligament healing. There also are some gaps in medical kn...

Diptheria Toxin And Interleukin2 Help Killing Melanoma Tumour Cells

...elanoma cells in mice.' Denileukin diftitox is a fusion protein made up of amino acid sequences for the diptheria toxin and the T cell growth factor, interleukin 2 (IL2). It targets Tregs that have IL2 receptors on their cell surface, and it binds to part of the receptor called CD25. Once it reaches the i...

A Novel Technique That Detects "Cancer Genes" From The Breath Of Smokers

..., in practice it is very different." TMPRSS2-ERG fusion prostate cancer: an early molecular event associated with invasion. The presence of a gene fusion in prostate tumors is significantly associated with aggressive cancer, metastatic spread, and an inc...

"Trojan Horse" Agent Halts Bone Metastasis in Mice

...ws wild in India, and used bacteria to produce the fusion protein. The agent is designed to enter new blood vessel cells in tumors through expressed VEGF receptors and, once inside, the "Trojan Horse" toxin destroys the cell, disrupting the ability of tumors to form blood vessels to supply the nutrients the...

Yeast Model Shows Promise as Alzheimer's Test

... be detected," said Liebman. "The system employs a fusion of the human A-beta peptide to a functional yeast ...ive in allowing cells to grow on test media if the fusion does not form aggregates." Liebman said the yeast model system can be used to develop a high throu...

NMNAT Protein Protects Against Nerve Cell Degeneration

...ad three copies of a gene for a protein that was a fusion of NMNAT and another protein. Bellen and his colleagues sought to determine whether NMNAT was actually protective by studying mutant forms of it in fruit flies or Drosophila melanogaster, a commonly used model organism. NMNAT exists in a single state...

Cake Walk – Plum Treats Sell Like 'Hot Cakes' During Christma

...s it is popularly known today, originated from the fusion of erstwhile customs, practiced in England around 1870. Popularly called the 'Plum Porridge', the dish became a specialty, just as Christianity began gaining ground. The plum porridge was eaten with a specific purpose. Christians usually observe a fa...

Outcomes of Surgically Implanted Hearing Aids

...surgical stages to allow for osseointegration,' or fusion to the bone, the authors write. 'Earlier implantation of bone-anchored hearing aids allows the younger children who receive them to benefit from earlier speech and language habilitation,' they conclude. Source-Eurekalert SRI...

Researchers Investigate Gene Linked With Circadian Liver Clock

...ctive liver clock with a strain carrying the mPer2 fusion gene. As expected, liver slices from the offspring without Dox did not exhibit circadian mPer2 expression; the liver oscillators had therefore been shut off. However, when Dox was added to the medium supporting the liver tissue, circadian rhythms mat...

Does Anti-TNF Therapy Control Ankylosis ?

... are all characterized by ankylosis, stiffness and fusion of bone in the spine and peripheral joints. Ankylosis is an incapacitating condition that ultimately results in loss of spinal mobility and function severely affecting a person's quality of life. Currently, inhibition of tumor necrosis factor á (TN...

Salk Scientists - Links Between Cancer and Aging

..., enabling investigators to easily see breakage or fusion of chromosomes that are characteristic of damaged DNA under the microscope. Then they artificially supplied the cultured cells with one of two genes-either a functional copy of the WRN gene, which is mutant or nonfunctional in Werner Syndrome, or a...

Masala Bhangra is the Latest Fitness Craze in US

An Indian American fitness guru has created a fusion of Indian bhangra and aerobics that has become the latest craze in the United States//. Sarina Jain, also dubbed the Indian Jane Fonda, is the creator of 'Masala Bhangra' and is credited with the introduction of Bhangra, the lively folk dance of P...

Nepal to Introduce Art of Living for Golfers

...ues complemented by music. The camp will also have fusion music for non-golfers, helping them to unwind, Kumar said. However, the high-flying guru, who has followers all over the world and was seen putting at the Gokarna golf course during a two-day private visit last week, will initiate golfers only on t...

Healing With Music Therapy

...sociate D. Turi, a guitarist from Italy, worked on fusion music till they purified strains effective on both...rther developing the magical powers of this unique fusion music worldwide. The two have collaborated to produce the music albums 'Lot Of Flowers' and 'Sweet V...

Chinese Doctors Perform World’s First Disc Transplant

...at it will not recur. These methods include spinal fusion - which surgically joins bones in the spine, making them rigid - or artificial material to replace the defective discs. In some cases these methods can even cause further degeneration of the discs above and below the area most affected. The proce...

Now Scientists Create a Sheep That's 15% Human

...fetal sheep at this early stage does not result in fusion at all.' Source-Bio-Bio Technology...

FDA Approves INFUSE Bone Graft for Use in Dentistry

...y the FDA as a replacement for autograft in spinal fusion procedures and for use in treatment of open tibia fractures. "FDA approval of INFUSE marks a major step forward in the future of implant dentistry" comments Dr. Andrei Mark of Central Park Oral Surgery in New York City. Dr. Mark, who was recently f...

Severe Complications of Circumcision: An Analysis of 48 Cases

...monly observed complication was preputio-glandular fusion that was seen in 25 cases (52%.). The other complications were as follows: meatal stenosis in 11 (23%); urethral fistula in 5 (10.4%); partial glandular amputation in 4 (8%); and a distal urethral fistula in 3 (6%). Lysis of adhesions and revisions w...

Bangkok Lures Visitors With Its Growing Gourmet Scene

...s that attract their clients, not the European and fusion fare offered at some of the five-star hotels and chic eateries. "Our clients prefer to 'do it local' so we?re more likely to hunt out a popular restaurant with locals and take our clients there for a local experience," she said by email from Melbo...

US Professors Develop Fusion Protein to Fight Cancer

...ls without damaging healthy, normal cells. The new fusion protein can be helpful in fighting lung, prostate ...es that are caused by chemo and radiotherapy. A fusion protein is the product of joining two genes or two proteins or peptides together. Fusion proteins ca...

Adherence of Nanoparticles to RBC- Very Effective Drug Delivery Method

...future treatment of hematologic disorders. This fusion of modern nanobioscience with cell biology and hematology is precisely the type of interdisciplinary study that the new Experimental Biology and Medicine is interested in publishing. Experimental Biology and Medicine is a journal dedicated to the pub...

Boutiques Flourish in Ludhiana

...advantage. They do not want the same design, but a fusion of traditional Punjabi and western. So that is really working a positive asset to us. We are also keeping a constant touch with what is latest not in India but what is latest in London and Canada. Boutiques too go international, as many have plans ...

Insights into Acute Promyelocytic Leukemia

...o chromosomes and gives rise to a protein called a fusion protein. In APL, the fusion protein, always involving the transcription factor RARA, acts as a potent transcriptional repressor ...

Cancer Patients in New South Wales to Receive Advanced Image Guided Radiation Therapy Treatments

...e risk prostate cancer and was planned with MRI-CT fusion and fiducial marker insertion, and treated with dose-escalated 7-field IMRT with online cone-beam CT and electronic portal image verification. "As a result of the technology now available at the NCCI, we will be able to provide patients with the mo...

New Insights into Prion Propogation

...on could propagate in yeast. "We showed that the fusion formed a prion in yeast and it was infectious," Liebman said. "It's the first time a prion from one organism has been propagated in another organism that normally lacks that prion. It demonstrates that totally heterologous prion propagation is possib...