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fragments in Medical News

Computer simulation captures immune response to flu

... inside the dendritic cell "present" protein fragments of the virus on the cell's surface for ... from the body, including the presentation of fragments of pathogenic proteins on the surface of ... by dendritic cells of disease-related protein fragments (antigens) to T cells more strongly impact ...

Parasites a key to the decline of red colobus monkeys in forest fragments

... McGill University in Montreal, surveyed 20 forest fragments near the western boundary of Kibale National ... density of potentially harmful parasites in these fragments to the undisturbed core forest of the park. ... four years, red colobus populations in forest fragments declined 20 percent, whereas populations of ...

Study reveals current multi-component vaccines may need reworking

... does this selectivity evolve? Does the process always focus on the peptid fragments that will provide the strongest immune response/protection? If not, can we ... not to the presence of a whole bacterium or virus, but instead to key fragments of those pathogens. Peptide-based vaccines are already used ...

4-in-1

... The peptide is present to specifically identify the cancer cells; the RNA fragments suppress the special cancer-cell genes, killing the cells. The magnetic ... RNAs) are introduced into the cell. These are short, double-stranded RNA fragments that bind specifically to the target mRNA. Inside the cell, a special ...

Urine Test for Heart Disease Shows Promise

... well in a small trial, German researchers report. The test looks for fragments of the protein collagen, which plays a major role in blocking heart ... and capillary electrophoresis, were used to find levels of 17 protein fragments that the researchers had identified as being associated with ...

PercSys Introduces Accordion CoAx(TM) Stone Control Device for Facilitating Percutaneous Kidney Stone Treatments

... to and fills the ureter in order to prevent the migration of stone fragments further down in the ureter during the fragmentation procedure. In this ... lithotripsy procedures to prevent the retrograde migration of stone fragments into the kidney. The 7mm and 10mm Accordion Stone Management Devices have ...

Give the foie gras a miss

... Journal of Food Safety, Nutrition and Public Health . Harmful proteins fragments known as amyloid fibrils associated with damage to brain cells in ... that a biochemical mechanism akin to the replication of similar protein fragments in the brain diseases Creutzfeldt-Jakob Disease (CJD), scrapie, and Bovine ...

Intellect Neurosciences, Inc. Grants to Top Tier Global Pharmaceutical Company License to Certain Alzheimer's Patents and Patent Applications

... aim to prevent the accumulation of aggregated beta amyloid protein fragments in the brain that are thought to be the root cause of Alzheimer's disease. ... as a spaghetti-like protein mass called amyloid plaques. The beta amyloid fragments are generated as a product of metabolism from the much larger Amyloid ...

Intellect Neurosciences, Inc. Validates Pivotal European Patent for Alzheimer's Monoclonal Antibody Platform

... aim to prevent the accumulation of aggregated beta amyloid protein fragments in the brain that are thought to be the root cause of Alzheimer's disease. ... as a spaghetti-like protein mass called amyloid plaques. The beta amyloid fragments are generated as a product of metabolism from the much larger Amyloid ...

Intellect Neurosciences, Inc. Grants to Top Tier Global Pharmaceutical Company an Option to License Certain Alzheimer's Patents and Patent Applications

... aim to prevent the accumulation of aggregated beta amyloid protein fragments in the brain that are thought to be the root cause of Alzheimer's disease. ... as a spaghetti-like protein mass called amyloid plaques. The beta amyloid fragments are generated as a product of metabolism from the much larger Amyloid ...

Suspected cause of type 1 diabetes caught 'red-handed' for the first time

... immune cells, known as dendritic cells, "red-handed": carrying insulin and fragments of insulin-producing cells known as beta cells. This can be the first step ... of very characteristic peptides. In addition to studying what protein fragments carried by dendritic cells are essential for causing type 1 diabetes, ...

Penn researchers find potential in yeast for selecting Lou Gehrig's disease drugs

... cause of cell toxicity. In earlier studies at Penn, researchers found fragments of TDP-43 that were abundant in the clumps found in the post-mortem tissue ... FTD patients. Knowing this, Gitler and colleagues chopped TDP-43 into many fragments to find the segments that are responsible for clumping and toxicity. They ...

Same process discovered to both form skeleton and protect it for life

... Interestingly, DAPT also blocks the action of secretases that snip into fragments the amyloid precursor protein (APP) in brain cells. Some of these cleaved APP fragments clump together to form "plaques" in the brains of patients with ...

Handheld DNA detector

... to a DNA sensor system to produce a characteristic signal for specific DNA fragments in a sample. Samuel Afuwape of the National University, in San Diego, ... of known DNA sequences that could match up - hybridize - with specific DNA fragments in a given medical or environmental sample. The key to making the ...

Antibody Engineering Company f-star Appoints Three Pioneers in Antibody Engineering and Development to its Newly Established Scientific Advisory Board

... the introduction of additional binding sites into antibodies and antibody fragments by engineering the non-CDR loops of constant or variable domains. Modular Antibody Technology allows for the creation of antibody fragments with antibody functionality and long half-life but much smaller size ...

Engineers developing new cements to heal spinal fractures

... type of fracture causes the vertebra to burst apart and in severe cases fragments of bone can be pushed into the spinal cord, says Dr Ruth Wilcox of Leeds ... of Medical and Biological Engineering. Surgeons may be able to join bone fragments together and stabilize the spine with the use of metal screws and rods, ...

GenVault's GenSolve(TM) Reagents Enable State-of-the-Art Genomic Analysis of Dried Blood Spots

... analysis and SNP genotyping studies. Previously reported methods for recovery of DNA from blood dried on Guthrie cards and FTA paper generated fragments of single stranded, denatured DNA which were unsuitable for such analyses. "What is exciting about the observations made in these publications ...

Music Had Charms to Soothe Prehistoric Man

... years ago and were found in France and Austria. Last summer, however, the German paleontologists found a nearly complete flute made of bone and fragments of three ivory flutes. Just like modern flutes, the ancient ones have holes that humans could cover to make different sounds when blowing through ...

Hysterectomies Could Be Source of Stem Cells

... cords, dental pulp and body fat. Together, these findings are of great interest, the researchers said. "Moreover, the use of human tissue fragments that are usually discarded in surgical procedures does not pose ethical problems," Jazedje said. More information The U.S. National ...

Torn Surgical Gloves Put Patients at Risk for Infection

... to a study published in the June issue of the Archives of Surgery . Sterile gloves worn by surgical staff can be perforated by needles, bone fragments and sharp surgical instruments, and the resulting holes enable skin-borne pathogens to travel from the hands of surgical staff into patients. In ...

Popular Alzheimer's theory may be false trail

... support. Glial cells, which outnumber neurons 10-to-1, are at the heart of a popular explanation for Alzheimer's disease that suggests protein fragments called beta amyloid Abeta for short clump together in the spaces between brain cells, causing memory loss and dementia. Inflammation theories ...

USC researchers identify DNA mutation that occurs at beginning point of T-cell lymphoma

... virus-infected cells. However, the beginning point, or inception, of most human lymphomas occurs when two chromosomes break and the resulting fragments are reassembled in an exchange. Researchers specifically looked at T cell acute lymphoblastic lymphomas (ALL). ALL accounts for half of all ...

Raptor Pharmaceuticals to Collaborate with Roche on Therapeutic Delivery Across Blood-Brain Barrier

... and 11/202,566, titled "Methods of increasing delivery of active agents to brain comprising administering receptor-associated protein ("RAP") fragments conjugated to active agents". About Raptor Pharmaceuticals Corp. Raptor Pharmaceuticals Corp. ("Raptor") is dedicated to speeding the ...

Synthetech Announces Fiscal 2009 Results

... in organic synthesis, biocatalysis and chiral technologies. We develop and manufacture amino acid derivatives, specialty amino acids, peptide fragments and proprietary custom chiral intermediates and specialty resins, primarily for the pharmaceutical industry. Synthetech produces advanced ...

National Press Club to Host 'NEWSMAKER' Media Briefing on Cancer Policy

... conquer cancer and help those affected by the disease, both when facing the uphill battles of treatment and their aftermath -- piecing together the fragments of their lives, relationships and spirits -- after post treatment care," says Drechsler. After surviving a life-threatening bout with Stage ...

The future of personalized cancer treatment: An entirely new direction for RNAi delivery

... Dowdy has studied the cancer therapy potential of RNA inhibition which can be used to silence genes through short interfering, double-stranded RNA fragments called siRNAs. But delivery of siRNAs has proven difficult due to their size and negative electrical charge which prohibits them from readily ...

First U.S. Face Transplant Recipient Recounts Ordeal

... years. According to the Associated Press , the gunshot destroyed Culp's nose, cheeks, the roof of her mouth and one eye and left hundreds of bone fragments and shotgun pellets lodged in her face. Only her upper eyelids, forehead, lower lip and chin remained. Culp could not breathe without the aid of a ...

Urine Test Predicts Vein Clot Risk

... value of urine tests to help determine the risk of cardiovascular disease. A German research group reported recently that a urine test looking for fragments of a different protein, collagen, might help detect an increased risk of heart disease. And in 2007, physicians at Brigham and Women's Hospital in ...

Scientists Find New Way to Create Stem Cells

... Ding and his colleagues reprogrammed adult cells by engineering and using recombinant proteins, which are proteins made from the recombination of fragments of DNA from different organisms. They experimented with these proteins until they found the exact mix that enabled them to gradually reprogram the ...

HIV handicaps itself to escape immune system pressure

... South Africa with one form of the HLA gene that helps the immune system control HIV, called HLA-B*5703. HLA genes encode molecules that display fragments of viral proteins, known as epitopes, on the surface of infected cells. When white blood cells known as cytotoxic T lymphocytes (CTLs) spot certain ...

Scientists discover way to jumpstart bone's healing process

... As the bone begins healing it must progress through specific, well-defined stages. First, osteoclasts cells that can break down bone clean up any fragments or debris produced during the break. Next, a layer of cartilage called a callus forms around the fracture that ultimately calcifies, preventing ...

Study assesses new surgical procedure for regenerating cartilage in damaged knee joints

... Cartilage Autograft Implantation System (CAIS), involves extracting cartilage from the healthy tissue that remains in the knee, breaking it into tiny fragments to enable it to grow and expand, fixing it onto a biologically reabsorbable scaffold, and then implanting the scaffold with the cartilage cells back ...

Glass tables: An overlooked safety threat

... glass doors and windshields are mandated to contain tempered glass, which is four to five times stronger than standard glass and breaks into small fragments that are unlikely to cause injury, no such standards apply to glass tables, neither patio nor indoor furniture. Injuries are typically caused when ...

Dendritic cells ensure immune tolerance

... body's immune defenses. Each T cell has a receptor on its surface for recognizing just one single antigen. Antigens are molecular structures, mostly fragments of proteins. T cells do not dock onto free antigens, however: they rely on other cells which can present antigens to them. It is the dendritic cells ...

DNA Testing Lays Romanov Murder Mystery to Rest

... the 1990s, the first five bodies were positively identified as the Tsar, the Tsarina and three of their children. The second set yielded 44 bone fragments and teeth which were subjected to three types of genetic testing: mitochondrial DNA, autosomal STR and Y-STR testing. The mitochondrial tests ...

Researchers solve mystery of deep-sea fish with tubular eyes and transparent head

... which suggests that they can eat a variety of small drifting animals as well as jellies. In fact, the stomachs of the two net-caught fish contained fragments of jellies. After documenting and studying the barreleye's unique adaptations, Robison and Reisenbichler developed a working hypothesis about how ...

Sunken, Unexploded Bombs Pose Cancer Risk

... gunnery and bombing range from 1943 to 2003. Porter found that corals, feather duster worms and sea urchins closest to unexploded bombs and bomb fragments had the highest levels of toxicity. In areas up to two meters away from an intact bomb or bomb fragments, concentrations of cancer-causing toxins ...

Rice U. conference to explore music's role in human cognition and behavior

... or with variations -- creates a predictability ideal for social situations. Classical music features musical statements broken into smaller fragments and reassembled in new forms. To process that music, the mind has to be active and diligent, according to Brandt. "Because of the cyclic nature ...

Obama Orders Review of FDA in Salmonella Outbreak

... United States, peanuts exported to Canada were found to be tainted. The shipment was refused by a Canadian distributor because "the peanuts had metal fragments in them," Sundlof said. The products were then returned to the United States and destroyed in November after the FDA rejected as "unacceptable" ...

U.S. Launches Criminal Probe Into Salmonella Outbreak

... United States, peanuts exported to Canada were found to be tainted. The shipment was refused by a Canadian distributor because "the peanuts had metal fragments in them," Sundlof said. The products were then returned to the United States and destroyed in November after the FDA rejected as "unacceptable" ...
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