enzymes

The flip side of AIDS cocktails – HAART regime damages live

...the cases the HAART regime cost elevation of liver enzymes to more than five times the upper limit of normal resulting in severe liver toxicity. The drug cocktails have however clearly improved the condition of the patient in terms of controlling the HIV disease but the side effects on liver forced many to ...

B Vitamin protects and lowers toxicity of Arthritis Drug

...ents taking the placebo had higher levels of liver enzymes than patients taking folate supplements, which indicate toxicity to the liver. The researchers also came out wiht the fact that any possible negative effect of folate supplementation on the efficacy of the drug can be overcome by increasing the...

Tea Tales

... damage that free radicals do to cells, neutralise enzymes essential for tumour growth and de-activate cancer promoters. A cup of tea supplies around 200 gms of flavanoids. The antiioxidant potency in a cup of tea is 400 per cent greater than a cup of orange juice while providing a far smaller intake o...

Garlic a day keeps cancer away

...sulfide in garlic is known to make the gut produce enzymes that clear out cancer-causing particles. Now two ...d it increased levels of the cancer-protecting gut enzymes by up to 60 per cent when given in amounts equivalent// to a moderate daily intake in humans.They sa...

Bayer Voluntarily Withdraws BAYCOL - A Drug Associated With 50 Deaths

...group of drugs that lowers cholesterol by blocking enzymes that are essential in the synthesis of cholesterol in the body. Bayer Pharmaceuticals has voluntarily recalled its cholesterol drug Baycol( cerivastatin ) because // it has been linked to approximately 50 deaths. Baycol can cause a muscular side eff...

Dark skin protects

...stem, which engulf invading microorganisms and use enzymes to kill them. "Melanin is a sticky molecule. The bacteria and fungi get tangled up, and it stops them from proliferating." Also, a protein called attractin is known to regulate both melanisation and immunity in humans, suggesting a link between the...

New test for heart attack

...ly helps detect heart problems. A test for cardiac enzymes allows doctors to spot those people with chest pai...mplemented. They do a blood test for three cardiac enzymes - troponin 1, creatine kinase-MB, and myoglobin - which are released into the circulation by damaged...

Vitamin B for Hepatitis

...aking the vitamin. High levels of aminotransferase enzymes indicate more active infection of the liver.// Investigators conducted a trial in this patient and two others with HBV infection to investigate the relationship. All had either failed treatment with interferon or could not tolerate the drug. While ...

Beehives to curb caries

...nt inhibitor of glucosyltransferase (Gtf) enzymes, enzymes that synthesize glucans from sucrose and promote the binding of cariogenic bacteria to teeth, critical steps in the development of decay. This natural substance is actually used by bees to strengthen and protect their hive from germs and foreign in...

Researchers trick Alzheimer's Enzyme

...untoward -- because they interact with proteins or enzymes other than the ones planned for. According to him...acetylchonlinesterase, was one of the first brain enzymes identified. It breaks down acetylcholine, the neurotransmitter that propagates nerve signals. Inhibi...

Tea can prevent aging

... damage that free radicals do to cells, neutralise enzymes essential for tumour growth and de-activate cancer promoters. A cup of tea supplies around 200 gms of flavanoids. The antiioxidant potency in a cup of tea is 400 per cent greater than a cup of orange juice while providing a far smaller intake o...

Compound of Broccoli combats breast cancer

... It does so by increasing the level of detoxifying enzymes in the body. However, high doses of sulforaphane are toxic to cells so it may not be a practical option for drug development - and the amount of broccoli you may need to get the benefits could be excessive. They have been working on a synthetic com...

Gene testing kit specific for Doctors

...bing. Some people have variants of genes for liver enzymes that mean it's hard for them to break down certain drugs. If they could be identified easily, the doctor could avoid prescribing these particular drugs and spare the patient the adverse effects....

A new discovery about Acetaminophen

...gents (NSAIDs). These drugs are known to block two enzymes - cyclo-oxygenase (COX)-1 and COX-2. It is COX-2 which generates pain signals, but COX-1 helps produce the protective mucus that lines the stomach. Inhibition of COX-1 leads to the sometimes serious side effects of NSAIDs like stomach irritation and ...

A new discovery about Acetaminophen

...gents (NSAIDs). These drugs are known to block two enzymes - cyclo-oxygenase (COX)-1 and COX-2. It is COX-2 which generates pain signals, but COX-1 helps produce the protective mucus that lines the stomach. Inhibition of COX-1 leads to the sometimes serious side effects of NSAIDs like stomach irritation and ...

Beehives to curb dental caries

...nt inhibitor of glucosyltransferase (Gtf) enzymes, enzymes that synthesize glucans from sucrose and promote the binding of cariogenic bacteria to teeth, critical steps in the development of decay. This natural substance is actually used by bees to strengthen and protect their hive from germs and foreign in...

Painkillers may protect against Alzheimer's disease

... drugs that relieve pain by blocking the action of enzymes called cyclooxygenases (COX), which control inflammatory responses. Although they are effective against pain, the drugs can cause ulcers and dangerous stomach bleeding. Researchers at the University of California, San Diego School of Medicine and the...

Viagra Also Found To Be Effective For Treatment of Lung Diseases

...use liver problems, so users must have their liver enzymes checked every month. Viagra works by yet another mechanism, inhibiting an enzyme called phosphodiesterase 5. The drug relaxes blood vessels, allowing blood to flow into the penis - or, it is hoped, into the lungs. However specialists say , approv...

Herb Found To Be Effective In Controlling Blood Sugar Levels

...and Sri Lanka. Salacia oblonga binds to intestinal enzymes that break down carbohydrates in the body. These enzymes turn carbohydrates into glucose, the sugar that circulates throughout the body. If the enzyme binds ...

Cure For Persistent Oral Fungal Problem May Be Possible

...can be increased if they can be protected from the enzymes that may destroy them. This may be achieved by sy...a protease inhibitor cocktail that may inhibit the enzymes that kill the peptides. This cocktail thus may be able to increase the ability of the peptides to tr...

Cell’s microenvironment linked to cancer

...wire format, tightly compressed protected from the enzymes which break them. "Medical research has for decades focused on finding the underlying genetic abnormalities that cause disease, but this work demonstrates that genes themselves are controlled by components outside the nucleus and these, in turn, ar...

Inflammation reduced by consuming oily fish

... are made from the omega-3 fatty acids by cellular enzymes and can reduce inflammation in mice. Resolvins were also identified in humans. Volunteers given omega-3 fatty acids and aspirin were found to have resolvins in their plasma. Human resolvins were shown to inhibit the movement of inflammatory cells. ...

In Search Of A New Drug To Target Cholesterol

...be to blame for the build-up. ACAT2 is one of four enzymes responsible for helping cholesterol leave the liver, where it is made, and travel to other parts of the body. ACAT2 most often helps cholesterol travel to the arteries, where it builds up into the deadly plaque. After studying mice who were genetica...

In Search Of A New Drug To Target Cholesterol

...be to blame for the build-up. ACAT2 is one of four enzymes responsible for helping cholesterol leave the liver, where it is made, and travel to other parts of the body. ACAT2 most often helps cholesterol travel to the arteries, where it builds up into the deadly plaque. After studying mice who were genetica...

Severe sleep apnea can cause liver problems

...a heightened risk for elevated levels of the liver enzymes and may result in hepatitis or fibrosis of liver. On looking into the health records of 163 people with suspected obstructive sleep apnea syndrome, patients with severe condition of the syndrome were also insulin resistant. Results of the study sho...

Enzyme for treatment of arthritis

... relief. Cathepsin G enzyme is part of a group pf enzymes called proteases. Proteases are the enzymes that are targeted when treating HIV patients in one of the treatment procedures. In targeting the en...

Simple Urine Test Can Help To Monitor Disfiguring Birthmarks

... the matrix metalloproteinases (MMPs), a family of enzymes required for angiogenesis, or growth of new blood vessels. Angiogenesis is also critical to a cancer's expansion, and Moses' lab was the first to show that inhibitors of MMP can inhibit angiogenesis. Recently, her lab also demonstrated that cancer...

Grape fruit seed extracts can heal stomach ulcers

...its the two enzymes, COX-1 and COX-2, as these two enzymes are responsible for maintaining the integrity of t...ound that the seed extracts, combines with the two enzymes COX-1 and COX-2 in promoting better healing of the stomach ulcers. The results of the study were p...

Causes of drug induced liver disease

...combination of liver cell damage measured by liver enzymes and incidence of jaundice by the drugs can cause deaths in 10 to 15% of the cases thus affected. The FDA uses the rule to assess the liver toxicity of the drugs before they are approved. The current study is the first one to scientifically test the ...

Research Shows Carbon Monoxide Prevents Inflammations

... outcome of an internal power struggle between two enzymes that control cellular production of these gases. The researchers say that Hmox and carbon monoxide gases are the body’s way of trying to limit tissue inflammation and injury induced by iNOS and nitric oxide during transplant rejection. Their data s...

An Anti-cancer Smart Bomb delivered using a Nanocell

... malignant pleural mesothelioma. Alimta blocks the enzymes necessary for DNA copying and cell division and the drug is supplemented with Vitamin B12 and Folic acid to minimize the side effects of skin rash and other effects. ...

The Link Between Oxidized Phospholipids And Coronary Artery Disease

...recent study researchers suggest that proteins and enzymes that remove or destroy oxidized phospholipids prevent atherosclerosis and that proteins and enzymes that produce or retain oxidized phospholipids promote atherosclerosis , hence they say that oxidized...

Controlled Gene Expressions Can Cure Many Diseases

...rted into proteins, but first is copied by special enzymes into many copies of messenger RNA, which then move..., or PNA, which physically binds to DNA and blocks enzymes from copying, or transcribing, the DNA into messenger RNA. More importantly, the researchers also em...

New Tools To Identify Flu Strains

...ss called PCR, or "polymerase chain reaction," and enzymes are released that "digest," or cut that DNA at certain points. "The way the gene is cut or not cut depends on which flu gene you have," Larson said. "Once the genes are cut, you can separate them based on size in a gel." The pattern of fragment size...

Cultivating gold on a fig tree

...ly modifying actinomycetes to produce??more of the enzymes which cause the gold to form....

Metal In Medicines Can Fight Diseases Effectively

...rdination complexes, mimic the activity of natural enzymes that break apart DNA, RNA, and proteins in the bod...lexes targeted these particular RNA structures and enzymes and destroyed them. The way the complexes work makes them different from most drugs. Researchers h...

Slowing Cartilage Loss In Arthritis With Fruit Extracts

...rom the fruit Pomegranate have been shown to block enzymes that contribute to cartilage degradation in osteoa...pomegranate fruit inhibited stimulation of certain enzymes in human cartilage cells affected by osteoarthritis. Production of these enzymes, matrix metalloprot...

Pomegranate Juice Is Helpful In Arresting Osteoarthritis

...y states that pomegranate fruit extracts can block enzymes // that contribute to osteoarthritis. The study...etalloproteases (MMP), which are tightly regulated enzymes necessary for tissue remodelling. When overproduced in a disease state, such as osteoarthritis, they...

Sugar Helps Control Cell Division

...ins inside cells 20 years ago. They now know which enzymes put the sugar onto proteins and which enzymes take it off -- and knocking out or blocking these enzymes allowed the researchers to control whether...

Cabbage And Genes May Protect Against Lung Cancer

... of reduces the toxic effects. These genes produce enzymes which eliminate the isothiocyanates in the blood and clean the body. Vegetables such as cabbage, broccoli and sprouts are rich in chemicals called isothiocyanates, which strongly protect against lung cancer, but the link between lung cancer and cru...

Vegetarian Food may protect against cancer

...of reduces the toxic effects and the genes produce enzymes which eliminate the isothiocyanates in blood and cleans the body Elizabeth Tait of the American Association for Cancer Research said, "For years, the conventional wisdom was that all vegetables are good and that may be true, but now we're finding t...

A Boon For Gastritis Patients In The Form Of Broccoli

...sumably by activating gastric mucosal anti-oxidant enzymes that can protect the cells from H. pylori-induced DNA damage," Yanaka concluded. Previous studies have already found that broccoli sprouts possess anticancer properties....

Soy Protein May Lower Cholesterol

...Eating soy protein increases the activity of these enzymes that break down the cholesterol." Source: University of Kentucky in Lexington...

Another Feather In The Garlic Cap: Helpful In Avoiding Breast Cancer

...othesized that PhIP enhances the metabolism of the enzymes linked to carcinogenesis. They further suggested that the diallyl sulfide derived from garlic might counter this activity. "We treated human breast epithelial cells with equal amounts of PhIP and DAS separately, and the two together, for periods ra...

Aspirin reduces skin cancer Risk

... of the gene COX leading to down expression of COX enzymes leading to hindering the growth of cancer cells. Researchers surveyed and compared 273 people with skin cancer to age matched 187 healthy persons for their sun spots with the differences in the use of aspirin/ Non-steroidal anti-inflammatory drugs (...

Regular light exercise slows down aging of the brain

...ories at a time, may be beneficial in changing the enzymes within our bodies that protect us from free radicals and remove damaged molecules." he said. Oxidative damage in the brain is believed to be a natural consequence of aging and a contributor to memory loss. In addition, increased oxidative damage has...

Chronic Myelogenous Leukemia (CML) Has An Answer Now!

...s that are normally controlled by another group of enzymes phosphatases. Because of Bcr-Abl, production of white blood cells gets out of control, leading to CML. At the early stage (chronic phase), the disease almost always responds to the anticancer drug Gleevec, which puts Bcr-Abl on hold. The drug was ha...

Cranberry juice to Prevent Dental Decay

... in plaque formation. The bacteria utilize certain enzymes called glucosyltransferases for construction of de...acid secretions. Cranberry juice also prevents the enzymes from being utilized and poses a threat to bacterial colonisation. If you probably think that rushi...

Zyflamend inhibits 78 percent of prostate cancer cells

...d was shown to decrease the activity of both these enzymes in a dramatic manner in the laboratory setting. "We are currently conducting a Phase I clinical trial for men with a pre-cancerous lesion of the prostate -- prostatic intraepithelial neoplasia -- to gain some information as to Zyflamend's potential t...

Tendency To Smoke and Get Addicted Could Run In Families!

...fied gene forms are found to decrease the level of enzymes involved in the metabolism of nicotine, more specifically found to account for slow processing of nicotine in the body. As a consequence of this effect, the brain is quickly exposed to high concentrations of nicotine. This gives the smoker a feeling ...

Mobilizing Stem Cells at the Injured Site Using Hyperbaric Oxygen Treatments.

... This was then followed by the triggering of other enzymes which helps in the movement of the stem cells to the site of injury for the healing process to occur. ...

Stem cells mobilized by hyperbaric oxygen

...bone marrow. This synthesis is believed to trigger enzymes that mediate stem/progenitor cell release." Further study of hyperbaric oxygen's impact on stem cells could lead to new treatments for combating injury and disease. ...

Little Known DNA Repair Enzyme May Be A Tumor Suppressor Gene

...pacts. Thanks to nature, our cells contain several enzymes dedicated to detecting and repairing any damage caused by these impacts. Failure of these enzymes to make needed repairs to genes in time can lead to the accumulation of mutations and, eventually, c...

Five New Anti-Inflammatory Compounds Produced By Indian Scientists

...use of such drugs hinders the functioning of other enzymes that play a vital role in the metabolic process. The incidence of gastrointestinal problems is yet another disadvantage, that restricts use of painkillers....

Bacteria born with drug resistance

...rategies by which the mechanism of drug resistance enzymes produced by the bacteria could be hindered and also requires better and new antibiotic production by pharmaceutical industries....

Safety Of Heart Drug Questioned

...surgery. The drug acts by blocking the function of enzymes that are involved in the clot dissolving process. The drug manufacturer, Bayer AG, a German based concern in response has stated that the drug has been approved following demonstration of adequate safety level in trials conducted by the company its...

Adult and Children Have Varied Drug Metabolism

...n their body for the processing of the drug. These enzymes vary in concentration with age. Hence this study...y life stages. The team studied about 14 different enzymes in children and adults. They findings were very surprising because several of the enzymes varied i...

New Compound Offers Hope In Liver Cancer Treatment

...r causing substances) by enhancing the function of enzymes that remove toxins from the body. Further results about the compound have been published in the journal Cancer Research. The compound has been found to be active (100 times effective than other anti-tumor compounds) at very small doses. It is hoped...

Molecular Computer Developed To perform Calculations From Within Human Body

...rs have developed a molecular computer, which uses enzymes to perform calculations from within the human body...New Scientist reported. According to the report, enzymes are already widely used to assist calculations. Molecular computers have the potential to surpass ...

Build Up of Protein in the Brain Linked To Alzheimer's

...on that the tissue in the organ also contains some enzymes that can actually digest some of the proteins, preventing its build up. The findings point to a pioneering effort by the researchers, indicating the presence of an inherent mechanism in the brain that can remove the beta-amyloid. "This newly uncover...