effector

New and unique treatment for Psoriasis patients

...he immune system goes amok and cells called memory effector T cells prompt skin inflammation. The treatments that are currently available for psoriasis range from ointments to ultraviolet therapy to other injected drugs that can broadly suppress// the immune system. The new drug Amevive, however has been desi...

Biopsies Of Human Skin And Bone Marrow Support T Cell Development

...lements of the immune system in the performance of effector functions, and serving as a repository for immunologic memory. The ability to generate T cells suitable for use in human patients could lead to significant advances in the treatment of immunodeficiencies and malignancies. Such therapies have not ye...

Altered Sodium Channel Function Linked to Heart Failure

...ion, and expression and activity of the calmodulin effector CaMKII is upregulated in humans with heart failure, Maier and colleagues investigated the effect of CaMKII on Na+ channel function. In this study, which appears online on November 22 in advance of publication in the December print issue of the Journa...

Immune System Gears Up by Specific Enzymes

...gets. When activated, certain T lymphocytes called effector T cells reproduce, increasing their numbers and en...ly reported that regulatory T cells, which prevent effector T cells from running out of control and causing damage to the body, use LAG-3 to rein in these activ...

How Plague-Causing Bacteria Disarm Host Defense

...ne have identified a novel molecular target for an effector protein called YpkA, one of several effectors of t...h a sophisticated invasion system that injects the effector proteins directly into the host cells cytoplasm. More than a decade after its discovery, our under...