Bone from blood: Circulating cells form bone outside the normal skeleton, Penn study finds
... PHILADELPHIA The accepted dogma
has been that bone-forming cells, derived from the body's connective tissue, are the only cells able to form the skeleton. However, new research ...
Anti-angiogenesis treatment improves hearing in some NF2 patients
... PhD, the study's senior author, formerly with the Steele Laboratory of Tumor Biology in the MGH Department of Radiation Oncology. "There had been a dogma
that these tumors do not produce edema and are not angiogenic, concepts that now need to be reevaluated." She adds that the study also suggests that ...
Statins May Cause Muscle Damage in Some Patients
... levels of CPK in the blood can mean the enzyme is leaking out of the muscle cells, indicating muscle damage.
"This paper is challenging the dogma
that if the CPK level is low, it rules out the possibility of muscle damage," Karas said. "You can have microscopic muscle damage and the level of ...
Trimming the fat boosts blood recovery after marrow transplant
... The fat cells seemed to somehow slow the natural cell cycle of the blood stem cells and progenitor cells.
"Our study contradicts the classical dogma
that bone marrow adipocytes are merely space fillers," says Daley. "Rather, they make it harder to recover from chemotherapy or radiation because ...
International team cracks mammalian gene control code
Another paper investigated retrotransposons, genetic elements that move around the genome and leave copies of themselves behind.
in the field is that retrotransposons are only active in cancer cells and cells that turn into eggs and sperm," Dr Faulkner said. "Our results showed ...
Treatment Target for Herpes Pinpointed
... that," Sawtell said.
VP16 is known to be important for starting the lytic, or reproductive, cycle upon infection of a cell. However, "it has been dogma
that VP16 is not involved in reactivation from the dormant stage," Sawtell said.
But in this study, which used a mouse model, production of VP16 ...
Heart regenerates after infarction -- first trials with mice
... the Max Delbrck Center for Molecular Medicine (MDC) Berlin-Buch and the Charit Universittsmedizin Berlin (Germany) have been able to show that this dogma
no longer holds true. Dr. Laura Zelarayn and Assistant Professor Dr. Martin W. Bergmann were able to show that the body`s own heart muscle stem cells ...
Free articles get read but don't generate more citations
... were published, open-access articles were downloaded more but were no more likely to be cited than subscription-based articles.
"The established dogma
is that freely available scientific articles are cited more because they are read more," said Davis, a former science librarian who designed the ...
Radiation for health
... the minimum possible exposure with no regard for radiation as a beneficial agent," says Luckey, "Those who believe the Linear No Threshold (LNT) dogma
have no concept about any benefits from ionizing radiation. Many radiobiologists get paid to protect us from negligible amounts of ionizing ....
New form of ECT is as effective as older types but without cognitive side effects
... that, a first principals analysis of ECT stimulation parameters, along with the results of Sackeim et al, suggest that we should rethink the dogma
of standard clinical ECT settings and work to optimize the therapy by bridging scientific understanding with clinical evaluation.
Schizophrenia Tied to Multiple Genetic Errors
"The idea that multiple rare mutations may account for a substantial portion of the incidence of schizophrenia is at variance with the current dogma
of the field, which is that a number of mildly deleterious, common alleles [genes] combine with environmental factors to lead to the development of ...
Gene plays 'Jekyll and Hyde' in brain cancer
... confirmed these findings in human glioblastoma tumors as well.
The belief that STAT3 can only be an oncogene has been a pretty entrenched dogma
in the field, says Bonni, so we performed many, many experiments to make sure this was correct. It took some very persistent investigators in my lab ...
Medical College of Wisconsin study finds drug may limit radiation kidney damage in BMT patients
... P. Cohen, M.D., professor of medicine in the division of nephrology, and principal investigator for the study. Our findings overturned the former dogma
that normal tissue radiation injury is untreatable, he says.
Kidney failure is a well known and serious complication of BMT and occurs in up to 50 ...
Scientists discover a direct route from the brain to the immune system
... It used to be dogma
that the brain was shut away from the actions of the immune system, shielded from the outside forces of nature. But thats not how it is at all. In ...
UF researchers track genetic journey of HIV from birth to death
... AIDS. The researchers tracked the viruses in each patient to find out when and where the telltale X4 population first appeared.
The general dogma
has always been that the X4 viruses are more pathogenic than the R5 viruses. And that really isnt true. People die from the R5 viruses, said Maureen ...
Study suggests loss of 2 types of neurons -- not just 1 -- triggers Parkinson's symptoms
... the death of most of the dopamine neurons suggested the existence of a system that can temporarily compensate for the loss of the dopamine."
in the field is that Parkinson's disease involves a selective loss of dopamine neurons. The truth is, if you look at postmortem Parkinson's disease ...
No Evidence Older Women Generate New Eggs
... with a follow-up study a year later in Cell, challenged the biological dogma
that mammals, including women, are born with a limited lifetime supply of ... and clinician-scientists at USF Health which affirms the traditional dogma
of a finite period of fertility in women, said Abdul S. Rao, MD, MA, ...
Routine Oxygen Administration in Heart Attack Victims, Challenged
... Zealand’s Medical Research Institute says it’s high time this ‘clinical dogma
‘ was challenged.
Writing in the Journal of the Royal Society of ... uncommon in the situation of a heart attack. We need to challenge clinical dogma
because the routine use of oxygen in myocardial infarction is not ...
Research Explains How Lead Exposure Produces Learning Deficits
... the normal development of newly born neurons in a part of the brain (hippocampus) known to be important for learning and memory.
“There was a dogma
in neuroscience that you were born with all the neurons you would ever have, but that thinking has changed dramatically in the last 20 years,” said ...
Flies too Have Immune Memory!
The evidence that a fruit fly's immune response can adapt to - or retain memory of - an earlier infection contradicts the long-held dogma
that immune memory cannot exist in invertebrates such as insects. Such memory of a specific pathogen, known as adaptation, is supposed to be a ...
Nobel Prize for Gene ‘Silencing
... via the messenger or mRNA to the cytoplasm to be transformed into proteins. This basic information, ‘DNA to RNA to Protein’, called the Central dogma
of Molecular Biology , forms the very basis of life. Proteins control all biological processes, noted examples being enzymes and antibodies.
Brain Regulation Present Even In Spineless Creatures
... "The biochemistry is altered. The translators that they use are altered. The shapes of the cells are altered, and their physiology is altered. The dogma
is that most cells don't change their characteristics, but here's a case of nerve cells changing not only one characteristic but almost all of them." ...
Researchers Find Molecular "Brake" to Cell Death
... these cells, Tang says.
But the notion of how to push cancer cells to die has been flawed, Tang says. These new findings "overturn a scientific dogma
so long accepted that it has become a textbook standard when talking about apoptosis," he continues.
Researchers agree that the seminal event ...
Tooth Decay Bacteria Unaffected By Altered Biochemical Pathway
... revealed that the tooth decay causing bacteria can carry out its destructive work without this pathway. "We were met with skepticism … because the dogma
was that this biochemical pathway is the key for all living cells," commented Jeannine Brady, Ph.D., a co-author of the study and an associate ...
Heart may pull Cells from Body to Self-repair
... were therefore probably electrically coupled and functioning with other heart muscle cells. Bohm's team concludes that "these results challenge the dogma
that the heart is not able to regenerate."
They added that although the percentage of regenerated cardiomyocytes is rather low, it might be ...