diffraction in Medical News

Varian, Inc. Acquires Oxford Diffraction, Ltd.

... in solutions. "The acquisition of Oxford diffraction is key to Varian's goal of broadening its range ... Rogerson, President and CEO, Varian, Inc. "Oxford diffraction has experienced rapid growth since its formation ... particularly in Europe. Oxford diffraction products will now be distributed on a global ...

Measurement technique probes surface structure of gold nanocrystals

... in the nanocrystal, resulting in a complicated diffraction pattern made of speckles similar to what is seen ... is reflected by a surface. When deciphered, the diffraction pattern describes the structural arrangement and ... Zuo said. Nano-area coherent electron diffraction makes it possible for us to probe the surfaces of ...

University of Pittsburgh researchers crack code of 3-D structure in key metabolic protein

... intensity parallel X-rays to the protein crystals in order to collect the diffraction data necessary to determine the proteins atomic configuration. These ... Highly advanced computational techniques were then used to analyze the diffraction data and to uncover, through complex mathematical approaches, the atomic ...

Unique skeletal muscle design contributes to spine stability

... a unique packing design consisting of short fibers arranged within rods, and that these fibers are stiffer than any other in the body. Using laser diffraction methods that they developed to measure muscle internal properties during back surgery, they demonstrated that the multifidus' unique design serves a ...

Cell phones using lens-free imaging promise to improve health monitoring

... captures an image of the microparticles in the solution using a sensor array. Because red blood cells and other microparticles have a distinct diffraction pattern, or shadow image, they can be identified and counted virtually instantaneously by LUCAS using a custom-developed "decision algorithm" that ...

A glass apart

... network had been undertaken. Using ISIS to study the relationship between these atoms and the host silicate glass via techniques unique to neutron diffraction has enabled us to move forward with the programme. The key outcome of our experiments has been a full understanding, at the level of atomic ...

IUPUI scientists report first 3-D view of anti-cancer agent

... X-ray crystallography is a widely used analytical technique in which X-rays are directed through crystals and results are deduced from the pattern of diffraction of the X-rays. Although bleomycin has been studied for 40 years and much is known about the mechanism of action of bleomycin, without an accurate ...

Scientists solve structure of gene regulator that plays key role in cancer

... crystals containing the protein of interest. The three-dimensional structure of the crystallized protein is deduced by analyzing the pattern of x-ray diffraction caused by the arrangement of atoms in the protein crystal. Marmorstein and his colleagues spent years attempting to crystallize p300/CBP a ...

SAFC Pharma Expands Its Pharmorphix Solid State Chemistry Services

... The development includes office reorganization and will facilitate installation later this year of additional state-of-the-art spectroscopic and diffraction equipment. SAFC Pharma Vice President of Manufacturing and European Operations, Michael Harris commented, "As new drugs and the regulatory ...

Researchers solve first structure of a key to intact DNA inheritance

... on a tiny loop in an X-ray diffractor and X-rays are beamed through it. Bending around the lattice of atoms in the crystal, the X-rays produce a diffraction pattern, which can be seen as a dot pattern on a monitor. A state-of-the-art X-ray diffractor shoots a different angle of the crystallized protein ...

First look at an enzyme target for antibacterial and cancer drugs

... which is powered by a superconducting bend magnet or superbend, and which has experimental facilities that offer both multiple-wavelength anomalous diffraction (MAD) and monochromatic protein crystallography capabilities. The high brightness of the x-ray beams and the experimental capabilities at Beamline ...

Telomerase enzyme structure provides significant new target for anti-cancer therapies

... interaction, Skordalakes and co-workers obtained the three-dimensional structure of TRBD using X-ray crystallography, a technique that analyzes the diffraction patterns of X-rays beamed at crystals of a molecule to determine the molecules atomic structure. Their studies reveal that the TRBD domain is ...

Northwestern exposing most deadly infectious diseases in 3-D

... scientists place a protein crystal -- just 1/10 of a millimeter -- into the Synchrotron x-ray beam. As the x-rays scatter off the crystal, the diffraction pattern reveals the location of the protein's electrons and atoms, a process called x-ray crystallography. In early November, the university will ...

Man-Made Proteins Could Be More Useful Than Real Ones

... crystallography, a technique in which x-rays are directed through a crystal of a protein so that its structure can be deduced from the resulting diffraction pattern. The researchers found that the Zwit1-F peptide folded into a bundle of coiled helices that resembled those in natural proteins. In ...

New Quartz References for Workplace Safety

... Monitoring silica dust in the workplace typically is done by collecting samples over a period of hours on a special air filter and using X-ray diffraction (XRD) to determine the amount of silica present in the sample. To be effective, monitoring requires accurate measurements of micrograms of silica on ...

Study Finds Astaxanthin Is Potent Inhibitor of Oxidation in Cell Membrane Model

... anecdotal human data, the results of the Mason study (Differential effects of carotenoids on lipid peroxidation due to membrane interactions; xray diffraction analysis by McNulty et al.) signify that astaxanthin exhibits potential utility for use as the scaffold for antioxidant/anti-inflammatory agents in ...

Three dimensional structure of apolipoprotein revealed

... X-ray crystallography. X-ray crystallography technique // is used for determining three dimensional structures so molecules by determining the x-ray diffraction patterns of the crystals present in molecules. Researchers feel that this new discovery will help a lot in understanding the mechanism of action and ...

New device for discerning Osteoarthritis

... only shows that the gap between the bones is getting narrower. Researchers at the University of Texas, have been developing a technique called diffraction enhanced imaging (DEI) that can create an image of cartilage. They have found it can be used to detect early Osteoarthritis, before it's visible by X ...