Chemotherapy in Medical News

Boehringer Ingelheim to Commence Phase III Study Investigating the Role of BIBW 2992 as First-Line Treatment for Non-Small Cell Lung Cancer (NSCLC) Patients with EGFR Mutations

... of the single-agent BIBW 2992 to that of standard chemotherapy (cisplatin/pemetrexed) as a potential first-line ... 1120 in combination with standard second-line chemotherapy in patients with advanced NSCLC. The studies are ... 1120 in combination with standard second-line chemotherapy treatments for patients with advanced NSCLC, is ...

Advanced targeted therapies effective as first-line treatment for lung cancer

... progression-free survival time compared to chemotherapy and combination treatments," said David Gandara, ... phase III study that compared oral gefitinib with chemotherapy as first-line therapy and analyzed the treatment ... and greater objective response rate compared to chemotherapy in patients with EGFR mutations," said Tony Mok, ...

Ongoing Study Shows That Endovascular Therapy is Associated With High Cure Rate for Childhood Eye Cancer

... with eye cancer (retinoblastoma) shows that chemotherapy delivered through endovascular (through the ... community, as results prove that chemotherapy delivered through endovascular techniques is a ... treatments fail, physicians resort to intravenous chemotherapy or radiation therapy. Despite this wide array of ...

Radiation Plus Chemo a Good Option in Lung Cancer

... Ill., compared 202 patients who underwent chemotherapy plus radiotherapy followed by surgery with 194 patients who underwent chemotherapy plus radiotherapy alone, which is the current ... the risks and potential benefits of definitive chemotherapy plus radiotherapy with, and without, a surgical ...

Oral Chemotherapy Offers Patients a More Convenient, Less Invasive Treatment Option

... in Elizabeth, New Jersey has new oral chemotherapy program in place LOS ANGELES, July 27 ... -- The increasing availability of oral chemotherapy for treating a variety of cancers--along with ... "The result of the greater emergence of oral chemotherapy regimens is a significant shift on a number of ...

Lilly to Unveil More Than 30 Studies at Premier Lung Cancer Meeting

... by the FDA in combination with cisplatin (another chemotherapy drug) for the initial treatment of advanced ... to maintain the effect of initial treatment with chemotherapy and whose disease has not worsened. ALIMTA is not ... alone or in combination with cisplatin, another chemotherapy drug, are low blood cell counts (red blood cells, ...

Surgery remans an option for advanced lung cancer

... Lancet has found that surgery after standard chemotherapy and radiation can be an option for patients. ... to a control group treated with conventional chemotherapy and radiation alone. The patients who did ... was randomly assigned to receive surgery plus chemotherapy and radiation, while a second group of 194 ...

Life after chemotherapy: Daily tasks, quality of life may be affected, MU researcher finds

... the issue of cognitive decreases following chemotherapy treatment. Click here for ... Mo. - Each day, thousands of people undergo chemotherapy treatments for different types of cancer, and it ... Medicine, studied women who had been treated with chemotherapy for breast cancer. The researchers tested the ...

US Oncology Research Network Participates in Phase III Follow-up Study to BiPar's Investigational Cancer Drug BSI-201

... significantly enhances the anti-tumor effects of chemotherapy and has shown promising safety and efficacy ... metastatic breast cancer with zero to two prior chemotherapy regimens for metastatic disease; adjuvant chemotherapy is allowed. Patients interested in learning more ...

Peregrine Pharmaceuticals Reports Financial Results for Fiscal Year 2009

... and compare favorably with historical data with chemotherapy alone. Recent analysis shows the median ... compare very favorably with historical data with chemotherapy alone and are especially encouraging in this ... study of the biologic effects of bavituximab and chemotherapy in patients with advanced lung cancer. ...

Research identifies successful new treatment for Hodgkin's lymphoma, reduces long-term risks

... Hasbro Children's Hospital has identified a new chemotherapy regimen for pediatric Hodgkin lymphoma (HL) ... of the first malignancies for which a curative chemotherapy regimen was developed. Schwartz says, "For decades, the chemotherapy regimens known as MOPP and ABVD had been the ...

Fluorescent probes may permit monitoring of chemotherapy effectiveness, Stanford study shows

... effect of workhorse cancer treatments such as chemotherapy and radiotherapy, they could more quickly pick ... got to learn to switch off this death mechanism. chemotherapy and radiotherapy aim to turn it back on." One ... 4 percent ownership stake. "The entire cancer chemotherapy field is very, very excited about probes like ...

European Medicines Agency (EMEA) Approves Cell Therapeutics, Inc.'s September Meeting Request to Discuss OPAXIO(TM) Marketing Authorization Application

... chemical entity. When bound to the polymer, the chemotherapy is rendered inactive, potentially sparing normal ... exposure to high levels of unbound, active chemotherapy and its associated toxicities. Blood vessels in ... bed allowing significantly more of the dose of chemotherapy to localize in the tumor than with standard ...

Elderly breast cancer patients receive chemotherapy if treated in private practices

... oncologist characteristics and the receipt of chemotherapy in elderly women with breast cancer and found that they were more likely to receive chemotherapy if treated by oncologists employed in a private ... only 15% of women got treated, and the use of chemotherapy is a judgment call by the oncologist. With regard ...

Lilly Receives Fourth FDA Approval for ALIMTA(R) (pemetrexed for injection)

... therapy is treatment given after initial chemotherapy but before new tumor growth. And while ... locally advanced or metastatic NSCLC after prior chemotherapy treatment.(4) In 2008, ALIMTA, in ... by the FDA in combination with cisplatin (another chemotherapy drug) for the initial treatment of advanced ...

Bladder Cancer No Longer a Death Sentence

... infections and parasites. Women undergoing chemotherapy and radiation for cervical cancer also have an ... dropped from 90% to 40%. Despite an aggressive chemotherapy program, his next CAT scan revealed three new ... expectancy dropped to around nine months. The chemotherapy left him feeling exhausted and sick, and he ...

U-M study finds voice box can be preserved, even with the largest cancers

... larynx can preserve their speech by opting for chemotherapy and radiation over surgery to remove the voice ... Cancer Center found that a single round of chemotherapy could identify those patients most likely to ... whose tumors did not respond to the induction chemotherapy were referred for surgery. Thirty-six people ...

For Kids With Leukemia, Radiation May Be Safe to Skip

... Today's chemotherapy regimen often is enough, study finds ... Research Hospital found that children who had chemotherapy alone had a longer remission period and ... been given radiation treatments. "Effective chemotherapy can cure up to 90 percent of all children with ...

Cell Therapeutics Completes Pixantrone NDA Submission and Requests Priority Review

... (CRu) compared to patients treated with standard chemotherapy (14 out of 70 patients (20.0%) for the pixantrone ... four out of 70 patients (5.7%) for the standard chemotherapy arm, p=0.02). No patient (0%) in the standard chemotherapy arm achieved a confirmed complete remission ...

Potential for noninvasive brain tumor treatment

... invasive treatment of brain tumors by combining chemotherapy with heat administered from the end of a ... the traditional approaches of surgery, systemic chemotherapy or radiation. The bioengineers designed and ... envision using this system in conjunction with chemotherapy drugs encased in heat-sensitive microbubbles ...

WVU Doctor Works to Reduce Cancer Burden in Africa

... trial of its type in Africa -- a low-dose chemotherapy regimen for people with AIDS-related ... studied. The research team chose a low-dose chemotherapy regimen because it's vital that cancer therapies ... early diagnosis. Development of more low-dose chemotherapy trials is also on the agenda. "The hope is ...

Trimming the fat boosts blood recovery after marrow transplant

... Seeking ways to improve blood recovery after chemotherapy or bone marrow transplant, researchers at ... transplant. Patients who have had radiation or chemotherapy show fatty infiltration in their marrow, and it's ... "Rather, they make it harder to recover from chemotherapy or radiation because they actively suppress blood ...

ASCO Research Foundation Grant Will Support Study of Peregrine's Bavituximab in Lung Cancer

... Award to Study Biology of Bavituximab and chemotherapy in Lung Cancer Awarded to Dr. David Gerber of UT ... study of the biologic effects of bavituximab and chemotherapy in patients with advanced lung cancer. ... A Pilot Study of the Biologic Effects of chemotherapy Plus Bavituximab in Patients with Advanced ...

Donor Stem-Cell Transplant Best For Acute Myeloid Leukemia

... in the United States. Treatment usually involves chemotherapy to achieve a first remission, but the best ... The traditional consensus has been to use chemotherapy or autologous transplants with patients in good ... vs. nonallogeneic stem-cell transplantation, plus chemotherapy for patients who had good, intermediate or poor ...

Medifocus, Inc. receives Authorization Approval from Health Canada to launch its pivotal Phase III clinical study of focused microwave heating for treatment of breast cancer in Canada

... heat energy in combination with neo-adjuvant chemotherapy over chemotherapy alone on large breast cancer tumor. The full ITA ... in the Thermo-chemo arm was 88.4% and for the chemotherapy alone arm the median tumor shrinkage was only ...

Consumer Watchdog to Congress: Put Patients' Bill of Rights Back on the Table

... Doug bought a policy that promised unlimited chemotherapy coverage. Only after Doug got cancer did the ... discover that their insurance policy limited chemotherapy coverage to $1,000 per day. chemotherapy commonly costs $17,000 or more a day. Dana was ...

I-SPY trial offers key insights into locally advanced breast cancer

... clinical trial designed to evaluate the impact of chemotherapy before surgery on patients with locally advanced ... cancers' should explore the potential of standard chemotherapy and/or clinical studies that add novel agents in ... tumors predicted the response of the tumors to chemotherapy drugs given in advance of surgery. The scientists ...

New Market Research Study Shows Lung Cancer Treatments Differ Significantly by Both Age and Geography

... key factor in determining therapy choice, with a chemotherapy doublet plus a targeted agent far more common in the US than in Europe. "While chemotherapy doublets remain the standard regimen for ... than 70, more than a quarter of patients are on chemotherapy doublets plus targeted agent." Randomized phase ...

Vandetanib shows clinical benefit when combined with docetaxel for lung cancer

... of a small molecule targeted agent and standard chemotherapy in combination for lung cancer. Roy Herbst, M.D., ... tyrosine kinase inhibitor can be combined with chemotherapy safely and effectively to provide systematic ... between May 2006 and April 2008; all had received chemotherapy previously. Participants were randomized to ...

New Data Support Use of Simple Test to Predict Endometrial Cancer Response to Chemotherapy

... help physicians predetermine the effectiveness of chemotherapy in treating a woman's endometrial cancer. ... States. "Limiting a patient's exposure to chemotherapy is important, however determining the appropriate ... individual patients will only respond to a single chemotherapy agent 30 percent of the time and while ...

New Insights, Inroads Against Breast, Ovarian Cancers

... cancer was in remission after one round of chemotherapy began a second round of chemo as soon as their ... the early treatment arm started their second-line chemotherapy (based on rising CA125 levels) 4.8 months earlier ... "This indicated that the early initiation of chemotherapy did not induce a longer remission and, despite ...

New treatment combination proves safe for head and neck cancer patients

... "We found that adding gefinitib to standard chemotherapy was well-tolerated by patients who had already received chemotherapy or were frail," said Dr. Argiris. "We had hoped ... The finding that the addition of gefinitib to chemotherapy can delay the growth of head and neck cancer ...

Avastin Shows No Benefit Against Early Stage Colon Cancer

... were randomly chosen to receive either standard chemotherapy for six months, or chemotherapy for the same period of time plus Avastin. Some ... that these patients can simply receive standard chemotherapy and wait until the tumor is actually causing ...

Surgery not necessary for most late-stage colorectal cancers

... their diagnosis and would typically start chemotherapy treatments three to six weeks later. The ... But with the development of better chemotherapy treatments in the past decade, doctors at MSKCC ... IV disease differently, and began to administer chemotherapy as initial treatment. Such treatments seemed to ...

Avastin Unsuccessful as Adjuvant Therapy in Setting of Stage II and III Colon Cancer but May Be Effective if Given for Longer Duration

... (Avastin) in combination with standard chemotherapy was not effective in prolonging disease-free ... (Avastin) in combination with standard chemotherapy was not effective in prolonging disease-free ... the primary treatment for colorectal cancer while chemotherapy and/or radiotherapy may also be recommended ...

Chemo Alone Is Best for Advanced Colon Cancer

... been the standard procedure, followed by chemotherapy several weeks after the operation. Surgery was ... and complications from the primary tumor, which chemotherapy was thought not to affect. However, "if the ... primary tumor were expected to cause. Advances in chemotherapy that do a better job at shrinking both the ...

ALIMTA(R) (pemetrexed for injection) Receives Positive Opinion From CHMP as Maintenance Therapy for Nonsquamous Non-Small Cell Lung Cancer

... treatment for NSCLC, it would mark the first chemotherapy approved for this indication. In the EU and ... combination with cisplatin, for the treatment of chemotherapy naive patients with unresectable malignant ... by the FDA in combination with cisplatin (another chemotherapy drug) for the initial treatment of advanced ...

Chemotherapy combination outcomes differ for aged, younger colon cancer patients

... determined that the more aggressive combination chemotherapy does not benefit older colon cancer patients as ... (Level 2, West Hall D2). Adding oxaliplatin to chemotherapy treatment with 5FU reduces the risk of recurrence ... received 5FU alone. "We found that adding chemotherapy agents to the standard 5FU regimen in older ...

Compliance and cost: Bitter pills to swallow in the age of oral chemotherapy

... (ORLANDO) Though the growing shift toward oral chemotherapy agents offers cancer patients greater freedom and ... increasing number of cancer patients who receive chemotherapy now do so at home, with the click of a pill ... "Re-Mission" were more adherent to their oral chemotherapy and antibiotic regimens and showed an increase in ...

New survey highlights growing concern about risk of infection in cancer patients

... infection may have on treatment outcomes in chemotherapy patients, as well as emerging antibiotic ... infections as the most commonly observed in chemotherapy patients. Cancer patients are at a higher risk ... immune system caused by both the cancer and chemotherapy treatment. Neutropenia, a low white blood cell ...