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Cell Conversion Shows Promise for Diabetes Treatment

... The study, published in the Aug. 7 issue of cell , also shows that the pancreas is capable of beta cell regeneration. While this approach was ... is determining whether the alpha to beta cell conversion can be kept under control. "Too ...

U.S. Stem Cell Research Seems to Focus on Two Lines

... -- Only two of 21 approved human embryonic stem cell lines are routinely used by researchers in the ... says a new study. The study found that two cell lines, known as H1 and H9, accounted for 941 of ... by scientists since 1999 for human embryonic stem cell lines housed at the two largest ...

ThermoGenesis Announces Launch of Res-Q System; New Device Expands Company's Presence in Bone Marrow Sector

... Res-Q(TM) 60 BMC ("Res-Q") System, an automated cell processing medical device for the concentration ... in minutes and delivers a high rate of stem cell recovery. The Res-Q System follows the late 2008 ... "We are excited to add a new member to our stem cell processing product family to help us access the ...

Sperm Cell Insights May Aid Stem Cell Research

... spot proteins that help sperm revert to stem cell state THURSDAY, Aug. 6 (HealthDay ... in the testis. The researchers reduced the stem cell population in the flies' testis to zero and found ... Erika Matunis, an associate professor of cell biology, said in a university news release. ...

iPierian Appoints Dr. Chad Cowan and Dr. Konrad Hochedlinger to Scientific Advisory Board

... and Hochedlinger are leading scientists in stem cell research and their addition to the iPierian SAB ... Harvard Medical School and the Department of Stem cell and Regenerative Biology, and assistant ... Harvard Medical School and the Department of Stem cell and Regenerative Biology, principal faculty ...

Cryo-Cell to Present Novel Adult Stem Cell Research During 2009 China Medical Biotech Forum

... the largest and most established leaders in stem cell innovation, will present data on the ... significant potential to develop into multiple cell types. Dr. Julie Allickson, Vice President of ... scientists committed to study this novel stem cell population for a broad range of regenerative ...

Bellicum Pharmaceuticals Announces Initiation of Phase I/II Clinical Trial of Novel Vaccine for Patients With Advanced Prostate Cancer

... a novel pharmacologically regulated dendritic cell vaccine for the treatment of prostate cancer. The ... and a potent and durable antigen-specific T cell response may be generated. The ... antigen dynamics, circulating tumor cell count, antigen-specific immune response, and ...

Celiac Disease Provides Clues To Solving Autoimmunity

... culprits and eliminate them from your diet. cell Science Systems has developed a laboratory ... involves not eating those offending foods. cell Science Systems has hundreds of examples of ... About cell Science Systems ...

Keryx Biopharmaceuticals Settles License Dispute With Alfa Wassermann

... signaling cascade that has been shown to induce cell growth and cell transformation. KRX-0401 has demonstrated both ... which are pathways associated with programmed cell ...

New Breastfeeding Supplement Designed to Improve Milk Production for Nursing Mothers

... B-6: Metabolizes fat and protein, facilitates cell growth, and supports the nervous and immune systems. B-6 is needed for red and white cell production. Folic Acid: Synthesizes DNA and aids in cell division. Vitamin B-12: Supports the nervous ...

Journal of Clinical Oncology Publishes TREANDA Study Demonstrating Significant Improvement in Overall Response and Progression-Free Survival in Chronic Lymphocytic Leukemia

... studies suggest that TREANDA may lead to cell death by a process known as apoptosis (programmed cell death) as well as by an alternate cell death pathway which disrupts ...

Researchers Identify New Method to Selectively Kill Metastatic Melanoma Cells

... - through self-digestion and programmed cell death. The study is published in the August 4 ... called NOXA that is involved with programmed cell death. This series of chemical reactions results ... involving self-digestion that leads to programmed cell death specifically in melanoma cells. Fisher said ...

Researchers identify new method to selectively kill metastatic melanoma cells

... through self-digestion and programmed cell death. The study is published in the August 4 print issue of the journal Cancer cell . "The present research provides a path that ... called NOXA that is involved with programmed cell death. This series of chemical reactions results ...

Keryx Biopharmaceuticals Announces Agreement with FDA on a Special Protocol Assessment for Phase 3 Trial of KRX-0401 (Perifosine) in the Treatment of Multiple Myeloma

... signaling cascade that has been shown to induce cell growth and cell transformation. KRX-0401 has demonstrated both ... which are pathways associated with programmed cell ...

Boehringer Ingelheim to Commence Phase III Study Investigating the Role of BIBW 2992 as First-Line Treatment for Non-Small Cell Lung Cancer (NSCLC) Patients with EGFR Mutations

... of BIBW 2992 as first-line treatment in non-small cell lung cancer (NSCLC) patients with epidermal ... a protein that is involved in the processes of cell division. These molecules are in the early stages ... 2992 and BSC Versus Placebo and BSC in Non-Small cell Lung Cancer Patients Failing Erlotinib or ...

Diagnostic tools and innovative therapies improve patient prognosis

... and treat at-risk patients to prevent cancer cell progression. "Identifying and treating ... exposed to environmental triggers before cancer cell presentation will reduce incidence of one of the ... Media link THE UNIQUE "SMELL PRINT" OF NSCLC cell LINES (ABSTRACT # B3.5) Recent studies have ...

Fox Chase finds that lung cancer patients respond to erlotinib following cetuximab therapy

... SAN FRANCISCO (August 1, 2009)Non-small cell lung cancer patients who have progressed on a ... as first-line treatment for advanced non-small cell lung cancer. Out of 53 patients who had ... is approved for use in patients with non-small cell lung cancer and cetuximab has been studied in ...

Advanced targeted therapies effective as first-line treatment for lung cancer

... therapies are designed to inhibit only cancer cell replication and tumor growth and are generally ... inhibit the attachment of EGF and stop cancer cell division. IPASS is a randomized phase III ... treatment for patients with advanced non-small cell lung cancer (NSCLC) whose disease has progressed ...

UF scientists program blood stem cells to become vision cells

... to specifically program an adult stem cell to become a new cell type," said Maria B. Grant, M.D., a professor of ... you can overexpress a protein unique to a retinal cell type and trick the ...

New test for safer biomedical research results

... culture dishes? Under the microscope, different cell lines are almost impossible to distinguish from ... infection? Contaminations with other cell lines or pathogenic agents are a common and well-known problem. Often they are the reason why cell experiments fail to produce useable or ...

AstraZeneca Submits New Drug Applications for ZACTIMA(TM) in Second-Line Advanced Non-Small Cell Lung Cancer

... for the treatment of advanced non-small cell lung cancer in patients previously treated with ... mbination with D ocetaxel I n non-sm A ll cell lung C ancer) is a Phase III randomised, ... and prostate cancer combined(i). Non-small cell lung cancer accounts for around 85% of all lung ...

BD Announces Results for Third Fiscal Quarter

... BD BIOSCIENCES ------------------------- cell Analysis $70,518 ... BD BIOSCIENCES ------------------- cell Analysis $139,251 $141,889 (1.9) ... BD BIOSCIENCES ------------------- cell Analysis $209,769 $222,075 (5.5) ...

JNCI news brief: Antibody linked to chemotherapy drug inhibits ovarian cancer in lab

... substantial antitumor activity in ovarian cancer cell lines and in mice, according to a study published ... tested the immunoconjugate in ovarian cancer cell lines, where it bound to cells with high levels ... a highly statistically significant difference. In cell lines, its antitumor effects were also ...

HPV Infection May Be Linked to Poor Head and Neck Cancer Survival Rates in African Americans

... (HPV) improves survival in squamous cell carcinoma of the head and neck. Furthermore, ... consensus on why blacks fare worse with squamous cell carcinoma of the head and neck than whites, but ... "practice changing." "Squamous cell carcinoma of the head and neck is one of the ...

HPV infection may be linked to poor head and neck cancer survival rates in African-Americans

... (HPV) improves survival in squamous cell carcinoma of the head and neck. Furthermore, ... consensus on why blacks fare worse with squamous cell carcinoma of the head and neck than whites, but ... the study "practice changing." "Squamous cell carcinoma of the head and neck is one of the ...

Low prevalence of HPV infection may be tied to poor prognosis for blacks with head and neck cancer

... the study, "practice-changing." "Squamous cell carcinoma of the head and neck is one of the ... Only 4 percent of black patients with squamous cell carcinoma in the study were HPV-positive, ... consensus on why blacks fare worse with squamous cell carcinoma of the head and neck than whites, but ...

MEK4, genistein and invasion of human prostate cancer cells

... genistein in prostate cancer cells by assessing cell invasion and gene and protein expression of ... (MMP-2), which is associated with cell invasion. Overexpression of MEK4 increased MMP-2 expression and cell invasion in prostate cancer cells; decreased MEK4 ...

Viagra Trial for Sickle Cell Lung Problems Halted

... for pulmonary hypertension in adults with sickle cell anemia has been stopped because of severe side ... a lowering in pulmonary hypertension in sickle cell patients." Pulmonary hypertension affects as many as 30 percent of people with sickle cell disease. "It's the highest risk of death, so it's ...

NHLBI stops study of pulmonary hypertension treatment in sickle cell patients

... for pulmonary hypertension in adults with sickle cell disease nearly one year early due to safety ... problem was episodes of severe pain called sickle cell crises, which resulted in hospitalization. No ... pulmonary hypertension in patients with sickle cell disease, one of the most common genetic blood ...

Comprehensive Look at Rare Leukemia Finds Relatively Few Genetic Changes Launch Disease

... myeloid progenitors to convert them from a normal cell to AML," the authors noted, referring to several ... about what it takes to transform a normal cell into a cancer cell. "The complement of genetic ... from normal controls and allow the uncontrolled cell division that is a hallmark of cancer. Downing ...

Amgen's Second Quarter 2009 Adjusted Earnings Per Share Increased 13 Percent To $1.29

... the first-line treatment of advanced non-small cell lung cancer (NSCLC). The Company also noted that ... was seen in glioblastoma multiforme and renal cell carcinoma when AMG 102 was administered in ... AMG 102 in the gastric, prostate, mCRC, and small cell lung cancer settings continue. ...

Millennium Pharmaceuticals Inc./Lymphoma Research Foundation funds lymphoma research

... are rare diseases. A member of LRF's Mantle cell Lymphoma Consortium (MCLC), Dr. Fu's work will focus on mantle cell lymphoma (MCL), an aggressive malignant B-cell form of non-Hodgkin lymphoma (NHL). Mantle cell lymphoma is a rare form of NHL accounting for 6 ...

Blood flow in Alzheimer's disease

... disease is not simply a by-product of nerve cell damage. When the researchers looked at brain ... In the normal brain, blood flow responds to nerve cell activity. If nerve cell activity in a particular part of the brain ...

Scientists Track Impact of DNA Damage in the Developing Brain

... Ph.D., a member of St. Jude Genetics and Tumor cell Biology, said the work provides a new model for ... the damage triggered apoptosis, or programmed cell death. But the findings suggested the greatest ... pathway and blocked the cells from completing the cell cycle. "The cells appear to undergo permanent ...

Quark Pharmaceuticals Announces Data Indicating Potential Utility of QPI-1007 for Treatment of Glaucoma

... QPI-1007 prevents progressive retinal ganglion cell (RGC) loss in an increased ocular pressure (IOP) ... Di Polo of the Department of Pathology and cell Biology, Universite de Montreal, indicate that ... in two additional models of retinal ganglion cell (RGC) death - induced by optic nerve crush or ...

Lilly to Unveil More Than 30 Studies at Premier Lung Cancer Meeting

... as a treatment for nonsquamous non-small cell lung cancer (NSCLC) in the maintenance setting, ... effective* in patients with nonsquamous non-small cell lung cancer (NSCLC) histology: An analysis of ... of patients (pts) with stage IIIB/IV non-small cell lung cancer (NSCLC) PD9.1.1: ...

Human cells secrete cancer-killing protein, UK study finds

... of cancer cells by binding to receptors on the cell surface. This discovery, published today in the leading journal cell , makes Par-4 a very attractive molecule for ... dependent upon extracellular Par-4 signaling via cell surface GRP78. Thus, the researchers conclude, ...

Bcl6 gene sculpts helper T cell to boost antibody production

... a single gene programs an immune system helper T cell that fuels rapid growth and diversification of ... in autoimmune diseases and development of B cell lymphoma, scientists at The University of Texas ... the crucial role in differentiating a nave T cell into a T follicular ...

Scientists discover key event in prostate cancer progression

... in the July 24, 2009, issue of the journal cell , focuses on androgen receptors, molecules ... these receptors to activate genes that control cell growth. The researchers show that in ... of genes involved in a different, later, phase of cell division, triggering ...

Leukemia cells evade immune system by mimicking normal cells, Stanford studies show

... together in the July 24 issue of the journal cell . Majeti shares his first authorship with Mark ... macrophages in mice, it allowed even the low-CD47 cell line to cause disease. All told, the evidence ... the low-CD47 group contained normal blood stem cell progenitors. "We've never before had the ...
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