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causative in Medical News

Genetic variations raise lung cancer risk for smokers and ex-smokers

... as the prime addictive compound in cigarettes, might also play a direct causative role in the development of lung cancer. There are five genes in the ... genes, that will be of great interest," Amos said. Another potential causative gene in the area is one that encodes a component of the proteasome, which ...

Recently discovered virus associated with pediatric respiratory tract infection in Germany

... morbidity and mortality in children worldwide. Accurate identification of causative agents is critical to case management and to prioritization in vaccine ... of the paper. In up to 50% of cases of severe respiratory disease, a causative agent is not identified, despite the application of PCR assays as well as ...

Orlando Regional Medical Center (ORMC) Implements PNA FISH(R) Tests to Help Provide Better Care for Patients with Bloodstream Infections

... infections in the United States causing over 90,000 deaths and significant costs to the healthcare system. Rapid and accurate identification of the causative pathogen is crucial to ensuring appropriate antibiotic therapy and improving patient outcomes in this critical situation. Conventional diagnostic ...

Generation of a severe memory-deficit mutant mouse by exclusively eliminating the kinase activity of CaMKIIalpha

... memory center of the brain, and is believed to be an essential mediator of activity-dependent synaptic plasticity and memory functions. However, the causative role of the enzymatic activity of CaMKII alpha in such processes has not been demonstrated yet, because this enzyme has multiple protein functions ...

At U.S. Colleges, Binge Drinking Is on the Rise

... college students for later alcohol addiction," Galanter said. "Heavier drink at this age is a predictor of later alcoholism and is likely a major causative factor." And Hingson said that efforts akin to what has been done to reduce smoking are needed to deal with the drinking problem among young ...

Favorable Vote From FDA Advisory Committee on SEROQUEL Pediatric Supplemental New Drug Applications

... during the first few months of therapy. In these patients, SEROQUEL should be discontinued at the first sign of a decline in WBC absent other causative factors. Patients with neutropenia should be carefully monitored, and SEROQUEL should be discontinued in any patient if the absolute neutrophil ...

Medizone Announces a Second Round of Trials Have Begun.

... our expectations in demonstrating significant bactericidal effects against C-difficile, E-coli, Pseudomonas aeruginous, MRSA and VRE, the main causative agents of hospital derived nosocomial infections. With the introduction of several new technological developments into this next series of trials, ...

Memorial University Medical Center (MUMC) Implements PNA FISH(R) Tests to Help Provide Best Care for Patients with Bloodstream Infections

... infections in the United States causing over 90,000 deaths and significant costs to the healthcare system. Rapid and accurate identification of the causative pathogen is crucial to ensuring appropriate antibiotic therapy and improving patient outcomes. Conventional diagnostic methods can take 48 hours or ...

Obesity and diabetes double risk of HF -- patients with both conditions 'very difficult' to treat

... by which those with diabetes have a higher risk of heart failure, and those with heart failure have a higher risk of diabetes. "But whichever is the causative factor," he adds, "it's very bad news for those with both conditions." ...

Leading Alzheimer's Disease Researcher Mark A. Smith, PhD Named Scientific Advisor at Advana Science

... shown to intervene early in at-risk populations to prevent beta-amyloid protein deposits and dissolve or disrupt existing beta-amyloid formations, a causative factor in Alzheimer's disease pathogenesis. These natural compounds have been isolated from plant materials and Advana is in the process of obtaining ...

New Data Demonstrate RISPERDAL(R) CONSTA(R) (Risperidone) Long-Acting Treatment May Improve Health Outcomes and Reduce Hospitalizations in Patients with Schizophrenia

... have frequent complete blood cell counts during the first few months of therapy. At the first sign of a decline in WBC and in the absence of other causative factors, discontinuation of Risperdal Consta should be considered. Potential for Cognitive and Motor Impairment: RISPERDAL(R) CONSTA(R) has ...

FDA Grants Approval for Use of RISPERDAL(R) CONSTA(R) as Both a Monotherapy and Adjunctive Therapy in the Maintenance Treatment of Bipolar I Disorder

... have frequent complete blood cell counts during the first few months of therapy. At the first sign of a decline in WBC and in the absence of other causative factors, discontinuation of Risperdal Consta should be considered. Potential for Cognitive and Motor Impairment: RISPERDAL(R) CONSTA(R) has ...

A Global Call to Action From HIV Co-Discoverers Robert Gallo and Luc Montagnier

... by Dr. Montagnier and his co-workers who showed the first existence of this new retrovirus and subsequently contributed to demonstrate its causative role in AIDS." Drs. Gallo and Montagnier are participating in a symposium, "25 Years After Discovering HIV as the Cause of AIDS," co-hosted by ...

AdvanDx Receives FDA 510(k) Clearance for EK/P. aeruginosa PNA FISH(R)

... clinicians. Treatment challenges are further compounded by conventional laboratory testing methods that take 24-48 hours or longer to identify the causative pathogen forcing clinicians to treat patients empirically. This empirical antibiotic coverage can lead to both unnecessary treatment with ...

Binax, Inc. Issues Clarification Re BinaxNow(R) Flu A & B Test

... SCARBOROUGH, Maine , May 1, /PRNewswire/ -- Binax, Inc., a leading provider of in vitro diagnostic tests to identify the causative pathogens of infectious diseases, announced that it has learned that inaccurate and erroneous information has been distributed to customers and ...

FDA Advisory Committee Recommendation on SEROQUEL XR Supplemental New Drug Applications

... first few months of therapy. In these patients, SEROQUEL XR and SEROQUEL should be discontinued at the first sign of a decline in WBC absent other causative factors. Patients with neutropenia should be carefully monitored, and SEROQUEL XR and SEROQUEL should be discontinued in any patient if the absolute ...

FDA Advisory Committee Recommendation on SEROQUEL XR Supplemental New Drug Applications

... first few months of therapy. In these patients, SEROQUEL XR and SEROQUEL should be discontinued at the first sign of a decline in WBC absent other causative factors. Patients with neutropenia should be carefully monitored, and SEROQUEL XR and SEROQUEL should be discontinued in any patient if the absolute ...

FDA Advisory Committee Documents for SEROQUEL XR Available on AstraZeneca Web Site

... during the first few months of therapy. In these patients, SEROQUEL XR should be discontinued at the first sign of a decline in WBC absent other causative factors. Patients with neutropenia should be carefully monitored, and SEROQUEL XR should be discontinued in any patient if the absolute neutrophil ...

People With MS May Have Lower Cancer Risk

... he and his colleagues "found that [the parents] did not have a notably increased or decreased overall cancer risk," suggesting that genes are not the causative factor. Instead, the researchers speculate that the lower risk for cancer among people with MS could be due to other factors. "It could be a ...

BioMosaics' Glypican-3 Antibody (clone 1G12) Validated at PhenoPath Laboratories for Immunohistochemical Detection of Liver Cancer

... Carcinoma, is one of the most common and aggressive malignant tumors worldwide, causing an estimated one million deaths annually. The main causative agents are hepatitis B virus (HBV), hepatitis C virus (HCV), as well as alcoholic cirrhosis and non-alcoholic steatohepatitis (NASH) which is ...

Statement From Sequella Founder and CEO, Dr. Carol Nacy at the 'Stop TB' Meeting in Brazil on the Eve of World TB Day

... Orphan Drug Designation in 2007. SQ109 shows activity against drug sensitive and multi-drug resistant (MDR and XDR) Mycobacterium tuberculosis , the causative agent of TB. SQ109 is due to begin a Phase 1B study to assess safety and pharmacokinetics of multiple doses of SQ109 in healthy subjects. ...

U.S. Department of Defense Exercises $2.0 Million Option to Fund Cethromycin Development

... but the FDA has not yet approved the drug for marketing in this or any other indication. About Tularemia Francisella tularensis is the causative agent of tularemia in humans. Though clinical infection causes a spectrum of illness from a mild flu-like syndrome to a life-threatening infection, ...

Scott Miller and Company Premieres "A CALL TO ARMS 2009 EDITION" at the Camelot Theaters in Palm Springs

... due to injury and damages from the anthrax vaccine. The US government is responsible for all liabilities. By not recognizing the anthrax vaccine as causative of harm to military personnel, government employees, and their children, the US government has not paid any damages to date even under the US ...

Mercy Integrated Labs Implements PNA FISH(R) Tests to Help Clinicians Provide Best Care for Patients With Bloodstream Infections

... infections in the United States causing over 90,000 deaths and significant costs to the healthcare system. Rapid and accurate identification of the causative pathogen is crucial to ensuring appropriate antibiotic therapy and improving patient outcomes. Conventional diagnostic methods can take 48 hours or ...

AstraZeneca Announces SEROQUEL XR is Now Available to Treat Bipolar Depression

... during the first few months of therapy. In these patients, SEROQUEL XR should be discontinued at the first sign of a decline in WBC absent other causative factors. Patients with neutropenia should be carefully monitored, and SEROQUEL XR should be discontinued in any patient if the absolute neutrophil ...

The Canadian Foundation for Global Health Announces a Research and Development Partnership with Medizone International, Inc.

... most, if not all, of these often fatal bacteria. The implications of such work are indeed profound as these pathogens are considered to be the main causative agents of hospital derived infections and collectively account for tens of thousands of lives lost each year in the US alone. So far we have ...

OSF Saint Anthony Medical Center Implements PNA FISH(R) Tests to Help Provide Best Care for Patients with Bloodstream Infections

... infections in the United States causing over 90,000 deaths and significant costs to the healthcare system. Rapid and accurate identification of the causative pathogen is crucial to ensuring appropriate antibiotic therapy and improving patient outcomes. Conventional diagnostic methods can take 48 hours or ...

Scientists identify new congenital neutropenia syndrome and causative gene mutation

... mutation (where one copy of the gene is mutated and the other is not) in the neutrophil elastase (ELA2) gene. In 2007, Klein's lab identified another causative mutation in a subgroup of SCN patients: homozygous mutations (where the defect is present in both copies of the gene) in the HAX1 gene. To conduct ...

Spry Debuts with 'Inspiration Everywhere'

... reset her priorities and ultimately led to a new business, Spa-Addicts.com, which offers discounts to spas around the country. "Our stories are causative and solutions-oriented," said Lisa Delaney, editor of Spry. "We're showing people you don't have to go through a dramatic, life-changing incident. ...

Once-Weekly Diabetes Drug Boosts Blood Sugar Control

... users had died of acute pancreatitis, a condition that can cause nausea, vomiting and abdominal pain. While Byetta use has not been confirmed as a causative factor in these deaths, the FDA has noted an association between Byetta use and pancreatitis, and on Aug. 18 announced it was working on stronger ...

Neurogenesis in the adult brain: The association with stress and depression

... by preclinical studies of stress (inhibiting cytogenesis) and antidepressive treatment (stimulating cytogenesis), but so far the existence of a causative relationship remains speculative. Nevertheless these findings should encourage further studies on neocortical cytogenesis and its function in ...

Researchers probe geographical ties to ALS cases among 1991 Gulf War veterans

... array of possible candidate environmental exposures could be reduced, it may be possible to identify or at least focus inquiry on specific potential causative agents." To narrow down the possibilities, Miranda and fellow investigators used GIS analysis, which allows researchers to layer different kinds ...

Summary Judgment Granted for SEROQUEL(R) Patent Litigation

... during the first few months of therapy. In these patients, SEROQUEL should be discontinued at the first sign of a decline in WBC absent other causative factors. Patients with neutropenia should be carefully monitored, and SEROQUEL should be discontinued in any patient if the absolute neutrophil count ...

How defects in 1 gene cause 3 distinct and devastating human diseases

... If you consider the linear sequence of XPD and map the [disease-linked] point mutations onto it, there is nothing clear about why they would be causative for one of the three diseases or another, said Jill Fuss of The Scripps Research Institute. By having these structures for XPD, we suddenly see how ...

Generation Rescue to Target Treatment-Based Research for Autism and ADHD - Jenny McCarthy, Deirdre Imus, and Katie Wright Join Board

... contact the Executive Director. "Our vision is to continue spreading the message that recovery is real and to be the leader in funding research for causative factors and biomedical interventions for Autism, ADHD and related conditions and to support families in need," added Mr. Kurtz. He concluded, "Most ...

FDA Approves AstraZeneca's Seroquel(R) for Maintenance Treatment in Bipolar Disorder

... first few months of therapy. In these patients, SEROQUEL and SEROQUEL XR should be discontinued at the first sign of a decline in WBC absent other causative factors. Patients with neutropenia should be carefully monitored, and SEROQUEL and SEROQUEL XR should be discontinued in any patient if the ...

NUCRYST Announces Management Realignment and R&D Portfolio Change

... About Clostridium difficile Clostridium difficile (also called C. difficile or C. diff) is a bacterium that is recognized as the major causative agent of colitis (inflammation of the colon) and diarrhea that may occur following antibiotic intake. C. difficile infection represents one of the ...

Different mutations in single gene suggest Parkinson's is primarily an inherited genetic disorder

... also currently being reported, originated from several different founders and is now found in 20 families on three continents. It is relatively causative in nature, meaning the majority of people with the mutation are likely to develop the disease. Parkinsons disease is fascinating to study because ...

Georgetown researchers find stem cell marker controls 2 key cancer pathways

... were especially interested in whether Msi1 is associated with cancer development because recent studies have suggested that stem cells may be the causative root of some cancers a notion that is vigorously debated among cancer researchers. It is really critical to understand if stem cells are involved ...

An unexpected way to cause leukemia

... AML have this mutation, but we could never be sure if it causes the disease. By precisely reproducing the human mutation in the mouse we now proved a causative relation, says Peggy Kirstetter, who carried out the research in Nerlovs lab. Instead of promoting uncontrolled proliferation of malignant blood ...
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