Bile in Medical News

New Tests Spot Tough-to-Detect Cancers Sooner

... devise method for early confirmation of bile duct, pancreatic cancers,, WEDNESDAY, ... it easier to diagnose cancers of the pancreas and bile ducts. In a study, the new tests more than ... . Doctors typically look for tumors in the bile duct and pancreas region by snaking an endoscope ...

Mayo Clinic finds new pathology tests double sensitivity to detect bile duct and pancreatic cancers

... ROCHESTER, Minn. - Pancreatic cancer and bile duct cancer are difficult to diagnose and often ... new tests that double the ability to detect bile duct and pancreatic cancers, according to a Mayo ... . Pancreatobiliary tumors such as bile duct cancer (cholangiocarcinoma) and pancreatic ...

Lumenis(R) Presents the SlimLine(TM) GI Laser Fiber: The Latest Advancement in Laser Lithotripsy for Gastroenterology

... stones that have formed or migrated to the common bile duct affect 10%-20% of patients with gallstone disease. (ii) Stones in the common bile duct and pancreatic duct can cause severe health ... available to these difficult stones in the bile and pancreatic ducts. "The SlimLine GI has ...

New Study Shows Probiotics Linked to Metabolism

... change was in how the treated mice metabolized bile acids. The primary function of bile acids is to emulsify fats in the upper gut. If probiotics influences the way bile acids are metabolized, they could change the ...

Study examines radiation dose estimates for pregnant women undergoing therapeutic ERCP

... life-threatening cholangitis (infection in the bile ducts) or gallstone pancreatitis (inflammation of ... inserted through the endoscope into the common bile duct and pancreatic duct connecting the liver and ... of choledocholithiasis (gallstones in the common bile duct). The occurrence of choledocholithiasis can ...

Penn researchers find a new role for a 'Foxy Old Gene'

... controls genes that maintain the proper level of bile in the liver. FOXA2 may become the focus for new ... to treat diseases that involve the regulation of bile salts. The study was published online this week ... where it helps to digest fats from food. bile salts, chemicals ...

Cellvizio(R) Confocal Microscopy Improves ERCP Bile Duct Cancer Detection, According to New Study Presented at DDW

... may now be able to better diagnose cancer of the bile ducts, one of the most difficult cancers ... a procedure used to diagnose cancer of the bile ducts and pancreas. Dr. Alexander Meining and ... the preoperative diagnosis of cancer of the bile ducts, medically known as cholangiocarcinoma, is ...

A patient who was diagnosed as IPN-B without hepatolithiasis?

... Intraductal papillary neoplasm of the bile duct (IPN-B) is a neoplastic lesion preceding ... papillary growth in the intra- or extra-hepatic bile duct. The authors reported a case of IPN-B with ... is especially helpful for the diagnosis of bile duct dilatation due to the infiltration of ...

Combining liver cancer treatments doubles survival rates, UVA researchers find

... advanced cholangiocarcinoma, cancer of the liver bile duct. Most patients who develop this type of ... therapy (PDT). The stents decompress the bile ducts, maintaining liver function. The combined ... and reduce tumor size. Cancer of the liver bile ducts is the second most common liver cancer and ...

New technique improves outcome for living donor liver transplants

... and composition of the liver and vascular and bile duct anatomy. Thanks to a review paper done at ... enhances high resolution imaging of the vital bile duct anatomy. CT scans provide a clear image ... been using an MRI to scan possible donors for bile duct anatomy, but Low said that, By using CT ...

Routinely used diagnostic approaches: only limited diagnostic sensitivity for bile duct cancer?

... is the only curative treatment in patients with bile duct cancer. To develop a therapeutic concept a ... Due to longitudinal tumor growth along the bile duct, imaging techniques including ultrasound, ... are of limited sensitivity for the detection of bile duct cancer. Brush cytology and/or forceps biopsy ...

How to effectively avoid many common complications and liver damage in bile duct exploration?

... fiber choledochoscopic exploration of the common bile duct, the much shorter incision required lessens ... fiber choledochoscopic exploration of the common bile duct and found that this kind of operation could ... with fiber choledochoscopic exploration of common bile duct was performed in patients with gallstones in ...

Combined stenting and photodynamic therapy improves survival in late stage liver cancer patients

... rates for patients suffering from advanced liver bile duct cancer, according to a study published this ... found that while stenting can help reinforce the bile duct to increase liver functionality, the light ... Cholangiocarcinoma (cancer of the livers bile ducts) is the second most common liver cancer and ...

U of I study: exercise to avoid gallstones!

... each year. Gallstones form when bile cholesterol levels become high enough to ... a half times; this resulted in there being more bile acids to solubilize the increased cholesterol so ... a similar set of genes that regulate liver and bile cholesterol metabolism. He also said that human ...

JCI online early table of contents: Jan. 10 2008

... of the liver protein AE2 and destruction of the bile ducts. The latter leads to a buildup of the waste product bile in the liver (a process known as cholestasis), ... treatment for PBC, administration of the bile acid ursodeoxycholic acid (UDCA), is ineffective ...

Simple Test Could Detect More Gastrointestinal Cancers

... other gastrointestinal cancers, such as those of the pancreas, stomach, bile ducts and esophagus. "Historically, we've approached cancer screening ... of esophageal cancers, 62 percent of pancreatic cancers, 75 percent of bile duct and gallbladder cancers and 100 percent of stomach and colorectal ...

Improved DNA stool test could detect digestive cancers in multiple organs

... colon cancer, the study looked at throat, esophagus, stomach, pancreatic, bile duct, gallbladder and small bowel cancers to determine if gene mutations ... of esophageal cancers, 62 percent of pancreatic cancers, and 75 percent of bile duct and gallbladder cancers. In this series, 100 percent of both stomach ...

Study Cites Gains in Gall Bladder Cancer Treatment

... high, new research shows. An estimated 9,520 cases of gallbladder or bile duct cancer were diagnosed in the United States in 2008, and about 3,340 ... The U.S. National Library of Medicine has more on gallbladder and bile duct cancer. -- Jennifer Thomas ...

Thus the bile does not overflow

... of the different cancers of the hepatobiliary system is blocked bile ducts. However, artificial catheters known as "stents" can remediate this problem. Stents are medical implants which reopen narrowed bile ducts to allow the outflow of bile. However, bacteria colonize these ...

Endoscopic ultrasound highly accurate in evaluating ambiguous radiographic findings of the pancreas

... or by X-ray. EUS can also be used to diagnose diseases of the pancreas, bile duct, and gallbladder when other tests are inconclusive, and can be used ... an enlarged HOP or dilation of the PD (with or without a dilated common bile duct). An EUS examination was initially performed by using a radial ...

Gallbladder removed without external incisions

... procedure was performed to treat painful gallstones, which form when bile in the gallbladder hardens into pieces of stone-like material. Removal of ... A small and non-essential organ, the gallbladder stores and releases bile as part of the digestive process. "This procedure marks the culmination ...

Aurora St. Luke's Named to U.S. News & World Report's Best Hospital Rankings

... Wisconsin and northern Illinois, particularly those with pancreatic or bile duct disease, Dr. Schmalz said. One such patient was a woman with a pre-cancerous polyp in a hard-to-reach bile duct. Once she was diagnosed, the gastroenterology team worked with Aurora ...

Digestive Disease Week study examined ACR's guidelines for CT colonography interpretation

... ERC immediately followed by cholangioscopy. Procedural indications were bile duct stones not amenable to removal by conventional methods or missed by ... initiate stone therapy. Stone location was 56 percent for the common bile duct (CBD), 22 percent for the common hepatic duct (CHD), seven percent ...

Hormone Replacement May Raise Women's Gallbladder Risk

... effect on the gallbladder, the authors explained. The gallbladder stores bile produced in the liver, and less estrogen collected in the bile could explain the reduced risk, the team noted. The findings were ...

UAB study shows investigational drug may treat biliary cancers

... drug triphendiol (NV-196) causes cell death in pancreatic and bile duct cancer cell lines, slows tumor growth and sensitizes tumors to ... triphendiol is more potent at inducing cell death in pancreatic and bile duct cancer cells compared to the chemotherapy drug gemcitabine alone at ...

Probiotics affect metabolism, says new study

... researchers was a change in how mice treated with probiotics metabolised bile acids. These acids are made by the liver and their primary function is to ... fats in the upper gut. If probiotics can influence the way in which bile acids are metabolised, this means they could change how much fat the body ...

OHSU researchers: Surgery, radiation gives early survival advantage in bile duct cancer

... surgery and radiation therapy is used for patients with a rare but deadly bile duct cancer. Surgery and radiotherapy shows an early response benefit. ... extraheptitc cholangiocarcinoma (EHCC), is an uncommon cancer of the bile ducts between the liver and gall bladder. Patients with this cancer ...

Combination targets: some drugs may work best when they work together

... and drug resistance, from lung and breast cancer to rare tumors of the bile duct. Synergistic effects of multi-level targeting of the MAPK and ... cholangiocarcinoma (CCA), a rare and deadly cancer of the ducts that drain bile from the liver, say researchers from Human Genome Sciences, Inc., a ...

Daiichi Sankyo Quietly Grows While Other Pharmaceutical Firms Downsize

... for marketing in May 2000. WelChol is the top-selling branded drug in the bile acid sequestrants (BAS) class. WelChol is different from most ... dose of any statin. WelChol is engineered for affinity and high capacity bile acid binding. It has been studied with our commonly prescribed statins -- ...

Cell Discovery May Bring Science Closer to Diabetes Cure

... associate professor of pediatrics at the University of Cincinnati College of Medicine. "This might be used one day to replace a diseased pancreas or bile duct in people." The study appears in the July 21 issue of Developmental Cell . More information The Nemours Foundation has more about ...

GIE: Gastrointestinal Endoscopy June issue study highlights

... below the surface such as a growth that was detected at a prior endoscopy or by X-ray. EUS can also be used to diagnose diseases of the pancreas, bile duct, and gallbladder when other tests are inconclusive, and can be used to determine the stage of cancers. Tissue samples, using a fine needle ...

Genetic Links to Rare Liver Disease Found

... primary biliary cirrhosis, a baffling disease that can destroy the liver. Primary biliary cirrhosis is an autoimmune disorder that blocks the bile ducts in the liver. It is a condition that mostly affects women, striking about one in 2,500 Americans. The current treatment works in about half of ...

NIH releases the first research plan to reduce the burden of digestive diseases

... Testing new approaches to detect, prevent and treat diseases of the liver and biliary system (organs and ducts that produce and move bile to help digestion) Using bioengineering, biotechnology, and imaging to improve patient outcomes and treatments Each year about 105 million ...

Medication may improve portal hypertension

... Research IDIBAPS of Barcelona, examined the effects of sorafenib on rats with portal hypertension induced by partial portal vein ligation or bile duct ligation. "Our present study is the first to determine if the multiple kinase inhibitor sorafenib causes beneficial effects on the ...

Long-term L-carnitine supplementation prevents development of liver cancer

... in liver tissues including clusters of hepatocytes with atypia and an increased proliferative rate, diffuse bridging fibrosis and nodule formation, bile ducts with marked reactive atypia showing nuclear enlargement, high nuclear/cytoplasmic ratio and prominent nucleoli. Interestingly, L-carnitine ...

Researchers Use Gene to End High Blood Sugar in Mice

... said. These stem cells normally act as reserves in case of liver injury. When the liver is damaged, the stem cells form mature liver cells or bile duct cells. But neurogenin3 changes their programming so that they become insulin-producing beta cells in the liver, the researchers said. The ...

Calcium associated with lower risk of cancer in women

... has been shown to reduce abnormal growth and induce normal turnover among cells in the gastrointestinal tract and breast. In addition, it binds to bile and fatty acids, potentially reducing damage to the mucous membrane in the large intestine. "In conclusion, our findings suggest that calcium ...

Potential atherosclerosis drug exhibits no harmful side-effects in liver

... proteins control a body's cholesterol levels by limiting the absorption of dietary cholesterol and by increasing the conversion of cholesterol into bile acids. Unfortunately, most LXR ligands also control fatty acid production, so therapeutic compounds that activate LXR also raise the levels of other ...

Help for liver transplant patients with small-for-size syndrome

... handle the metabolic demands of the recipient. The syndrome causes liver dysfunction soon after the transplant; symptoms include problems with bile flow and coagulation, and ascites, which is the accumulation of fluid in the abdomen. Without treatment, about 50 percent of patients with SFSS will ...

Gut instinct: Salmonella bacteria's molecular tactics to cause illness

... the body's multiple defense mechanisms. A corrosive course The bacteria are tenacious, surviving acidic pH conditions, digestive enzymes, bile salts, antimicrobial peptides, and other hazards as they pass through the stomach and intestine, and invade the mucosa of the small intestine. Once ...