autoimmune

Naked DNA Vaccination May Conquer Arthritis and Multiple Sclerosis

...DNA vaccination, holds the potential of overcoming autoimmune diseases such as multiple sclerosis and rheumatoid arthritis. The vaccine is currently being successfully tested in animals. In multiple sclerosis (MS) and rheumatoid arthritis (RA), the body essentially attacks itself, causing inflammation. In MS,...

Heart disease threat starts early in life for Diabetics

Diabetes mellitus type I, is due to autoimmune destruction of the pancreatic islet cells that produce insulin. Result of this the body no longer produces insulin and and there is a raise in the blood sugar levels. Individuals with this type I Diabetes develop are at a higher risk to develop heart...

Risk of heart disease begins in teens

...ietetics Association (ADA). Type 1 diabetes is an autoimmune disorder in which the body no longer produces insulin, the hormone that clears the blood of glucose after a meal and deposits it into body cells to use as fuel. Patients must inject insulin several times a day to manage the disease. Complications of ...

B Vitamin protects and lowers toxicity of Arthritis Drug

Rheumatoid arthritis is an autoimmune disease that most often affects women in their 30s and 40s, especially women.The illness causes the immune system to attack the joints, which can cause pain, inflammation and joint destruction. Methotrexate is the standard drug used to treat the...

New Way To Treat Lupus

...rt, kidney and central nervous system. Lupus is an autoimmune disorder, meaning the immune system mistakenly attacks the body's own tissue. New research into lupus suggests how the immune system goes awry in the disease//--a discovery scientists say could lead to better, more targeted treatments for lupus in t...

FDA Approves New Arthritis Drug, Bextra

...Unlike rheumatoid arthritis, which is an inherited autoimmune disease, osteoarthritis results from overuse of joints, and can be a byproduct of strenuous sports, obesity or aging. Pharmacia Corp. makes the drug, Bextra (valdecoxib), while drug giant Pfizer Inc. is helping to promote it. Bextra is a member of a...

Higher Risk of Asthma in children with autoimmune disease

A new study has found that children with some autoimmune diseases have an increased risk of asthma. In the ...ed the prevalence of asthma in children with three autoimmune conditions : celiac disease, type 1 diabetes and rheumatoid arthritis. Celiac disease is an inherit...

Hope For Stiff-Person Syndrome

...s unknown, doctors had suspected that it may be an autoimmune disorder. About 1 in every million people has the disorder, though it is often misdiagnosed and may be more common than recognized. Up to 65% of patients cannot perform daily tasks because of total-body stiffness or frequent falls. Some patients rel...

Defence against free radicals

... ailments such as cardiovascular disease, strokes, autoimmune diseases like arthritis and diabetes, cancer and Alzheimer’s disease. The researchers from the Medical Research Council’s Dunn Human Nutrition Unit in Cambridge found that molecules known as - uncoupling proteins can move a powerful free radical – ...

Arthritis Drug May Cause Liver Damage

...mphoma, high blood pressure and a life-threatening autoimmune disorder called Stevens-Johnson syndrome among Arava users compared with methotrexate, he said....

A way to slow the progression of Type 1 Diabetes

...tolerance to the beta cell, which is the target of autoimmune destruction in type 1 diabetes. This was in effect achieved, because the clinical effect we saw persisted long after patients had finished treatment with the anti-CD3 antibody....

Protein in eye fights diseases

...dy, a protein in the eye has prevented and stopped autoimmune eye disease in animal studies. Now, researchers sa...his could lead to promising treatments for other// autoimmune diseases such as multiple sclerosis and type 1 diabetes. Scientists from the Schepens Eye Research ...

Fireflies help speed development of new drugs

...r testing of new drugs for cancer, blood diseases, autoimmune disorders, heart attack damage and others, as these molecules could provide real time information about the effectiveness of new medications. Apart from the above use, these molecules could also be used to monitor the various cell processes....

Prediction Of Disease In The Future Questioned

...he blood of healthy individuals may predict future autoimmune diseases, such as rheumatoid arthritis and lupus. Researchers analyzed // past studies and found autoantibodies (antibodies that attack the body's own tissue) are often apparent several years before an illness manifests. According to a recent study ...

Asbestos Exposure Associated With An Increased Risk For Autoimmune Disease

...sure to asbestos may lay the groundwork for future autoimmune diseases such as rheumatoid arthritis and multiple sclerosis. Researchers examined 50 residents from Libby, which is known to be polluted by asbestos. They found these residents were more likely to have a class of autoantibodies known as antinuclear...

Weight Training Found To Be Effective In Treating MS

Multiple sclerosis is thought to be an autoimmune disorder, where white blood cells attack fatty tissue surrounding nerve fibers of the central nervous system. Statistics show that MS is twice as common in women as in men . // A new study shows weightlifting can help patients with multiple sclerosi...

New Oral Medication That Could Arrest Autoimmune Diseases In its early Stages

...s produced // in very large amounts in people with autoimmune diseases. This overproduction triggers a number of...to the development of an oral medication to arrest autoimmune diseases in the early stages....

Target of diabetes type 1 identified

...tes autoimmunity and may also change the way other autoimmune diseases are studied. Diabetes type 1 is a metabolic disorder that happens due to rising levels of sugar in the blood, and mostly is due to defects in insulin secretion, insulin function or both. Type 1 diabetes is caused when specific cells that p...

Low immunity in people with multiple sclerosis may be genetical

...y of the body against multiple sclerosis and other autoimmune diseases like diabetes and arthritis. This is the first study that establishes an association between multiple sclerosis and the FOXP3 gene. The research suggests that lower expression of the FOXP3 gene suppresses the functions of the regulatory T ce...

Identification of gene

The mystery of what causes the fatal autoimmune disease Systemic Lupus Erythematosis has been solv...elf from non-self. In people with lupus and other autoimmune diseases such as arthritis, the body’s white blood cells, instead of destroying invading bacteria an...

Lasik surgery effective in correcting vision

...nursing (d) Using steroid drugs (e) Suffering from autoimmune disorders like rheumatoid arthritis, lupus, Sjogresis syndrome etc. Before the lasik procedure you have to undergo eye examination including refraction of your eyes, corneal topography, pachymetry and retinal evaluation, to make sure that you will b...

Good News For Those Of You Suffering From Rheumatoid Arthritis

...ealed by joint X-rays. Rheumatoid arthritis is an autoimmune disease, which develops when certain cells of the immune system malfunction and attack healthy joints. The cause of rheumatoid arthritis is unknown. The primary focus of the inflammation is in the synovium, the lining tissue of the joint. Inflammator...

Researchers Find Out The Cause Of Immune Attacks Behind Hearing Loss

...riggered the antibodies in patients suffering from autoimmune sensori-neural hearing loss or AISNHL.// In the A... hearing. The patients were suspected of having an autoimmune cause for their hearing loss, and all received steroids, but they hadn’t been formally diagnosed. T...

Skin cancer linked to usage of Drug Azathioprine in organ transplants

...lants,// arthritis, inflammatory bowel disease and autoimmune disorders is found to increase the incidence of skin cancer in these patients. Professor Peter O’Donovan and colleagues from London Research Institute in Hertfordshire has found that Azathioprine accumulates in the DNA of the patient taking the drug...

Therapeutic Genes Transferred By Viral Vector Through T Cell Masking

...stem for the treatment of cancer, inflammation and autoimmune diseases. The new delivery system acts as a “T // ...s home to disease sites -- such as inflammation or autoimmune disease -- might benefit from this approach,...

Mineral Oil exposure increases risk of Rheumatoid Arthritis

...een help responsible to a certain degree. It is an autoimmune disorder, characterised by malfunctioning of the immune system resulting in inflammation of the bones and joints. There is a severe disablity, accompanied by joint swelling and pain. There is no satisfactory treatment currently available for the di...

Mineral Oil exposure increases risk of Rheumatoid Arthritis

...een help responsible to a certain degree. It is an autoimmune disorder, characterised by malfunctioning of the immune system resulting in inflammation of the bones and joints. There is a severe disablity, accompanied by joint swelling and pain. There is no satisfactory treatment currently available for the dise...

Molecule Behind Multiple Sclerosis Discovered

...scovered that a single molecule is the cause of an autoimmune disease in the central nervous system, called transverse myelitis (TM). This disease is related to multiple sclerosis//. In a study published in the October issue of The Journal of Clinical Investigation, researchers from Johns Hopkins University Sc...

Synthetic protein found to relieve arthritis symptoms in animal model

.... The original work was carried out on a very rare autoimmune disease called autoimmune lymphoproliferative syndrome (ALPS). Previously, it has been shown that PLAD blocks a cell surface...

High-Fat Diet Can Ward Off Inflammation In The Gut

...the gut. This feature may help the body prevent an autoimmune reaction where food is taken as a foreign particle//. Fat rich foods stimulate the intestine to trigger the release of an enzyme called a hormone called cholecystokinin, or CCK. This enzyme is responsible for digestion of the food and also satiatio...

Monoclonal antibodies show promise in treatment of blood cancer

...lls could be a pioneering treatment for leukemias, autoimmune diseases and transplant rejection//. B cells are...tiple myeloma and acute lymphoblastic leukemia and autoimmune diseases like rheumatoid arthritis and lupus. The findings of the study have been published in the o...

Stem Cells Can Be Used To Kill Cancer Cells

...could be used to treat several types of leukemias, autoimmune diseases and transplant rejections. In the present study, researchers were also able to accurately study how the immune system woks when confronted with unknown invaders. "We hear a lot about the potential of stem cells to treat conditions such as ...

Carnitine deficiency in children and adolescents with type 1 diabetes

...ss of insulin secreting beta-cell due to selective autoimmune destruction of the pancreatic beta cells. In this type exogenous insulin is required to prevent diabetic ketoacidosis....

Ketoacidosis Is The Main Cause On Mortality In Childhood-Onset Type 1 Diabetes

...ss of insulin secreting beta-cell due to selective autoimmune destruction of the pancreatic beta cells. In this type exogenous insulin is required to prevent diabetic ketoacidosis....

Effect Of Cooling And Exercise To Be Analyzed In Patients With Multiple Sclerosis

Multiple sclerosis is a form of autoimmune disorder that occurs in individuals who produce antibodies against their own cells or tissues. In multiple sclerosis, the antibodies are directed towards the fatty sheaths around nerve cells. // Fatigue is the most common symptom of the disease. It ...

Macrophage Inhibitory Factor Causes Multiple Sclerosis Progression

... Multiple Sclerosis: Multiple Sclerosis is an autoimmune disease which is caused by non-recognizing of its own body cells by the immune system leading to an immune response of activating immune cells against the body’s own cells. In Multiple Sclerosis the immune cells produces an immune response against th...

Study Offers Insights Into Treatment Of Rheumatoid Arthritis

...fecting more than 2.1 million Americans. It is an autoimmune disorder that is characterized by inflammation of ... seem to infiltrate tissue randomly, re-sulting in autoimmune inflammation. In aggregate synovitis, T and B cells meet each other in aggregates and inflame the jo...

Novel Actemra monotherapy in treating patients with early aggressive rheumatoid arthritis

... of pain. Rheumatoid arthritis is a debilitating autoimmune disease in which the lining of the joints becomes inflamed causing irreversible joint damage and destruction. Actemra (tocilizumab) is a humanized anti-human interleukin-6 (IL-6) receptor monoclonal antibody. A monoclonal antibody is used to denote a...

‘Life Cell’ In India Can store Cord Blood Stem Cells and Save Live

... kidney cancer, liver diseases, coronary diseases, autoimmune and inflammatory diseases can be treated using stem cells. Currently stem cells are being used to treat leukemia – a type of blood cancer effectvely....

New Test For Early Detection of Non-Small Cell Lung Cancer

...arker-based diagnostics for biodefense, cancer and autoimmune diseases. Contact: Louise DuPont mldupo00@email.uky.edu 859-323-6363 University of Kentucky...

Bird flu drug avoids blood vessel leakage

...roduced by the cytokines (immune cells) causing an autoimmune destruction of the lungs leading to increased infl...d immune response against the virus which leads to autoimmune destruction of the lungs leading to death. The new drug designed by the researchers contains active ...

Autoimmune disorder caused due to mutation in cryopyrin protein

...roducing hypersensitive immune response leading to autoimmune disease. // The protein Cryopyrin is activated by the bacteria against which the protein produces an immune response by activating IL-1 beta, which produces signals for the immune system to produce an immune response against the invading bacteria. ...

Weizmann Institute of Science says Immune Cells Could Help Maintain Brain Function

...tz's group demonstrated that this could be done by autoimmune cells. These cells are designed to recognize the body's own cells. But they are thought to be dangerous in the brain. This new research says that these cells may fight off senile diseases like Alzheimer's and Parkinson's diseases, glaucoma, amyotroph...

Statin drugs for arthritis and cardioprotection

...atoid arthritis is a systemic chronic inflammatory autoimmune disease against rheumatoid factor which causes pain, stiffness, swelling in joints. The treatment for rheumatoid arthritis is aimed at reducing the inflammatory reaction and preserving the movement of joint. Japanese researchers have reported in th...

TNF Protein Can Predict GVHD Bone Marrow Transplant Recipients

...own to play a role in a variety of inflammatory or autoimmune diseases, including septic shock, rheumatoid arthritis and Crohn's disease. Anti-TNF drugs are already FDA-approved and available on the market. We are currently conducting a clinical trial using one of these drugs, etanercept, in clinical trials to ...

Aluminium and Iron Could Play a Vital Role in Multiple Sclerosis

Multiple sclerosis (MS) is an autoimmune disease. Immune cells destroy the myelin sheath that surrounds nerve fibers in the brain and spinal cord. // The myelin is very essential in transmitting the impulses across the body. Scientists at Keele University, Staffordshire, compared the leve...

Gold Therapy- A Potential Treatment For Autoimmune Diseases

...d the use of platinum and gold in the treatment of autoimmune disorders. The mechanism of how gold helps in the treatment of rheumatoid arthritis and other autoimmune diseases // has remained a mystery. It has now been found that platinum or gold can prevent the dise...

Bombings in Japan have left Indelible Health Impression

...tion exists between radiation exposure and thyroid autoimmune diseases. 'Careful examination and follow-up of thyroid diseases are still important long -- 55 to 58 years -- after radiation exposure because the present results indicate that radiation dose effects on thyroid nodules, including benign and malign...

Vaccine to Impede MS Is In the Trials

Multiple Sclerosis (MS) is a degenerative autoimmune disease affecting the central nervous system. In this disease immune cells attack the brain’s myelin sheath. // It is a layer surrounding nerve fibers in the brain and spinal cord that allow the brain to transmit the electrical signals that stimulate...

Early Diagnosis Of Oral Cancer And Sjogren's Syndrome Possible By Saliva-Based Tests

...on for Dental Research.// Sjogren's syndrome is an autoimmune disorder that is characterized by dry eyes, dry mouth and rheumatoid arthritis. "If we can catch someone with oral cancer at stage 2 instead of stage 4, we can improve this person's 5-year survival rate by 50 percent, which would be of tremendous ser...

A Sneak Preview of Human’s Susceptibility to Auto Immune Disease, Allergy, Asthm

...ight lead to allergies, asthma and a host of other autoimmune disorders like juvenile rheumatoid arthritis, skin disorders, juvenile diabetes and autism. A study conducted among European kids who severely restrict the use of medicines such as antibiotics and fever reducers are at a lower risk of developing al...

Gene Therapy Helps To Cure 'Incurable' Illness

... aged 25 and 26, had been treated for a hereditary autoimmune disease over the past two years at Frankfurt University Hospital. She said the new technique might prove suitable for other diseases where people are born with a defective gene. Gene therapy is a procedure involving the alteration of a person's geno...

Prestigious Gairdner Awards for medical research in 2006 Goes To Two Yale biologists

...be honored for her 'discovery of the reactivity of autoimmune sera with nuclear riboprotein particles and elucidation of the rules of small nuclear RNA in gene expression.' Thomas D. Pollard, M.D., Sterling Professor and chair of Molecular Cellular and Developmental Biology at Yale will also receive the award...

Fair-Skinned People Need Minimal Sun Exposure To Produce Vitamin D

...hinning disease osteoporosis as well as in several autoimmune diseases. "We've had so many public health messages that people don't know what's common sense any more," said Dr Lucas, a fellow at the National Centre for Epidemiology and Population Health. However, the researchers cautioned that dark-skinned peop...

Epstein-Barr Virus May Be May Be A Cause For Multiple Sclerosis

...ce the risk for multiple sclerosis (MS), a chronic autoimmune disease that affects the central nervous system, a...that relates Epstein-Barr virus infection to other autoimmune diseases, particularly systemic lupus erythematosus (lupus), suggests that Epstein-Barr virus may ha...

Type 2 Diabetes Could Be Tackled Using Curry Colouring and Fat Mix

...osteoarthritis, rheumatoid arthritis and lupus, an autoimmune disease against the skin. His Fellowship will pay for staff, lab and research work. UQ's Deputy Vice-Chancellor (Research) Professor David Siddle said Dr O'Sullivan's project was one of many leading-edge CICR projects. "Our determined immuno...

Unraveling the Secrets of MHC in Human Genome

...e from infection or by governing susceptibility to autoimmune diseases or cancer. The MHC is one the most diverse regions of the human genome and its diversity are thought to have been shaped by widely varying evolutionary forces. The procedure is described in the Proceedings of the National Academy of Sciences...

Vitamin D In Pole Position At Clinical Endocrinologists Meet

...n many chronic diseases, including common cancers, autoimmune diseases such as type 1 diabetes and multiple sclerosis as well as cardiovascular heart disease. Michael Holick, MD, Professor of Medicine, Physiology and Dermatology at Boston University School of Medicine and author of The UV Advantage is scheduled...

A New study Throws Light On The Growth & Functions Of Insulin Producing Beta Cells

...d instead of the long viewed theory that it was an autoimmune disease. Their recent research suggested that type 2 diabetes includes a variety of diseases caused by multiple defects in the insulin-production, insulin-signalling and insulin-using system. The older studies using traditional techniques did sugge...

EBV Might Trigger Multiple Sclerosis, Study

...es for better control of the damage caused in this autoimmune disorder. The culprit, the researchers say, may ...nfected by Epstein-Barr virus but did not have the autoimmune disease. They then isolated from each patient the T cells that specifically responded to EBNA1. A ...