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Vessels in Medical News

Mathematics taking guesswork out of plastic surgery tissue transfer

... a flap, that is fed by a single set of perforator vessels an artery and vein that travel through ... skin and fat. Surgeons generally agree that vessels at least 1.5 millimeters in diameter are required ... apart; the rate of exchange of oxygen from vessels to tissue; and the pressure under which the blood ...

European Medicines Agency (EMEA) Approves Cell Therapeutics, Inc.'s September Meeting Request to Discuss OPAXIO(TM) Marketing Authorization Application

... chemotherapy and its associated toxicities. Blood vessels in tumor tissue, unlike blood vessels in normal tissue, are porous to molecules like ... distributed to tumors due to their leaky blood vessels and trapped in the tumor bed allowing ...

Study in Nature: MicroRNAs hold promise for treating diseases in blood vessels

... mechanism controls whether muscle cells in blood vessels hasten the development of both atherosclerosis ... blood pressure. Because VSMC surround blood vessels that are continually becoming clogged by ... growth limit, however, the growth that once kept vessels open begins adding to clogs by thickening vessel ...

UNC scientists identify growth factor as possible cancer drug target

... angiogenesis protein, SFRP2, found in the blood vessels of numerous tumor sites, including breast ... stimulates angiogenesis and is present in blood vessels of a wide variety of tumors provides us with a ... begins in the cells lining the blood or lymph vessels for which options for therapy are limited. ...

Morphotek(R), Inc. Announces FDA Acceptance of Investigational New Drug Application for MORAb-004, a Monoclonal Antibody for the Treatment of Solid Tumors

... is necessary for the development of new blood vessels (a process called angiogenesis). New blood vessels are required to provide blood flow to tumors for ... which are cells that surround the smallest blood vessels and are needed for the survival, migration and ...

Model for new generation of blood vessels challenged

... developing treatments. New generation of blood vessels takes place in normal physiological processes, ... How new generation and in-growth of blood vessels takes place has not been fully understood. It has ... the same. On the other hand, new generation of vessels in wound healing and tumor growth, for example, ...

Abbott's XIENCE V(R) Demonstrates Impressive Low Rates of Repeat Procedure, Stent Thrombosis and Major Adverse Cardiac Events in Complex, 'Real World' Patients in SPIRIT V Study

... that need treatment, and patients with smaller vessels (reference vessel diameter less than or equal to ... size matrix, including XIENCE PRIME SV for small vessels and XIENCE PRIME LL for long lesions. XIENCE ... in-stent neointimal growth in the coronary vessels following stent implantation, due to its ...

Why do people with Down syndrome have less cancer?

... blocks angiogenesis, the development of blood vessels essential for cancer's growth, since their ... an extra chromosome 21 would have far fewer blood vessels than teratomas from iPS cells with the normal number of chromosomes. She was right: blood vessels budded in the Down teratomas, but never fully ...

AZOR(R) Receives FDA Approval as First-Line Treatment for High Blood Pressure

... pressure can cause permanent changes to blood vessels and the heart that may create serious problems ... Angiotensin II is a hormone that causes blood vessels to tighten and narrow. Together the two medicines relax the blood vessels so that blood can flow more easily. Benicar ...

Study in Nature Medicine establishes major new treatment target in diseased arteries

... a single protein prevents early damage in blood vessels from triggering a later-stage, frequently lethal ... also found high CypA levels in the rupture-prone vessels of humans with AAA, and that major drugs like ... three of the most destructive forces in blood vessels oxidative stress, inflammation and matrix ...

Positive Results for Ophthotech's Novel Therapy for Wet AMD - Study of Anti-PDGF and Anti-VEGF Therapy Shows Significant Neovascular Regression and Enhanced Visual Outcome

... is characterized by the abnormal growth of blood vessels (neovascularization) beneath the retina, which ... form is characterized by the growth of new blood vessels into the central region of the retina. These new vessels cause severe visual loss due to retinal damage ...

Drug inhibits neuroblastoma blood supply in pre-clinical tests

... Cancer Center have found a way to prevent blood vessels from aiding the growth of neuroblastoma, a ... AMD3100, hinders the formation of tumor blood vessels and reduces human neuroblastoma tumor growth by ... Pericytes are essential for organizing blood vessels to feed tumors. Without pericytes, ...

USC researchers develop new drug to target tumor cells and blood vessels

... to target tumor cells and surrounding blood vessels without the negative side effects typically ... Sunday, April 19. "If left behind, the blood vessels within the tumor will help the tumor cells to ... also showed smaller tumors and fewer blood vessels in the tumors, with a 35 to 40 percent reduction ...

JCI online early table of contents: April 13, 2009

... is a disease of the major arterial blood vessels that is a common cause of heart attack and ... inflammatory disease of the major arterial blood vessels that is a common cause of heart attack and ... molecules that accumulate in regions of blood vessels affected by atherosclerosis. Detailed analysis in ...

Growth factor TGF-B helps maintain health of retinal blood vessels

... as TGF-β is essential to the health of blood vessels in the retina and that blocking it can cause ... of the molecules that help to maintain blood vessels in a healthy state," says Patricia D'Amore, PhD, ... team. Capillaries are the smallest blood vessels in the body and the site at which oxygen and ...

Blood protein may hold key to stopping tumor growth in cancer patients

... angiogenesis the body's formation of new blood vessels from existing blood vessels and how some blood proteins are involved in that ... shut down blood vessel growth. Because new blood vessels supply a steady stream of nutrients and oxygen ...

3-D snapshots of eyes reveal details of age-related blindness

... "wet" form of AMD, in which abnormal blood vessels grow in between the layers of the retina. 3-D OCT ... wet form -- including lasers that burn the blood vessels and drugs that inhibit the growth of new vessels -- can only slow, not stop, vision loss. ...

Drug-Eluting Stents Show Promise for Leg Arteries

... "We've traditionally used balloons to get these vessels open, but because the vessels get pretty small as you get down below the thigh, ... are not everything you'd dream of." Because vessels in the leg are either much larger or much smaller ...

Seaweed and fireflies brew may guide stem cell treatment for peripheral artery disease

... reconstituting or increasing the number of blood vessels to replace or augment those choked off by plaque ... marked by vastly reduced circulation of blood in vessels feeding the legs and other "peripheral" body ... "We could use standard X-ray angiography of blood vessels to see the transplanted cells. When they lit up ...

'Seeing' Stem Cells Helps in Fight Against Peripheral Arterial Disease

... Puts Puzzle Pieces Together in Regenerating Blood vessels to Open Clogged Arteries, Uses Firefly-like ... how to use stem cells to create new or more blood vessels to treat peripheral arterial disease (PAD) in ... have extensive disease -- with so many blood vessels affected -- that they're difficult to treat," ...

UT nanoscientist gets $7 million DoD Innovator Award for breast cancer research

... The remaining drug circulates through blood vessels and can kill healthy, non-cancerous tissue. Side ... of both and designed to hone in on the blood vessels that support tumor growth. Once there, the ... that penetrate the walls of the inner blood vessels and enter the diseased cells. The third stage is ...

CTI Focuses on Late-Stage Drug Approvals and Commercialization and Cuts Operating Costs: to Close Bresso Research Center

... and its associated toxicities. Blood vessels in tumor tissue, unlike blood vessels in normal tissue, are porous to molecules like ... distributed to tumors due to their leaky blood vessels and trapped in the tumor bed allowing ...

Big-hearted fish reveals genetics of cardiovascular condition

... for building properly formed blood and lymphatic vessels during embryonic development by sealing the ... defectsmainly leakinessin the heart, in blood vessels in the lung, and in the lymphatic system. Second, ... that whatever it's doing is fundamental to blood vessels and the whole cardiovascular system." The ...

Society of Interventional Radiology Hosts 34th Annual Scientific Meeting

... rarely and may include injuries to the blood vessels that can cause prolonged and sometimes ... cell therapy to determine how to regenerate blood vessels to open clogged or narrowed arteries to treat ... by exploring the treatment of the smaller blood vessels below the knee (typically difficult to treat ...

New Advances May Treat Stroke Faster, Better

... may also work well to reopen brain blood vessels clogged from strokes, according to new research. ... to be an effective and safe way to reopen blood vessels blocked after an ischemic stroke. Ischemic ... Mocco said he achieved success in reopening vessels when inserting stents up to about eight hours ...

'Normalizing' tumor vessels leaves cancer more benign

... spread: by normalizing the shape of tumors' blood vessels to improve their oxygen supply. Such a treatment ... "In tumors, the endothelial cells lining blood vessels grow in all directions and over each other," said ... of tumors, that haphazard overgrowth of blood vessels and deteriorated endothelial lining impairs their ...

Innovative method to starve tumors

... tumours use to stimulate the growth of the blood vessels that feed them. The researchers have also ... communicate with the endothelial cells of blood vessels and stimulate changes in their behaviour. The ... the abnormal formation of new blood vessels. The vessels then grow towards the tumour and supply it with ...

Researchers Identify Novel Mechanism That Make Cancer Tumors Grow

... a new pathway that could explain how blood vessels form within tumors. LOS ANGELES, Feb. 10 ... into cells that form the lining of blood vessels called "vascular endothelial cells" (VEC). These VEC cells then become incorporated into the blood vessels that form within tumors. "This is exciting ...

Mesh-like network of arteries adjusts to restore blood flow to stroke-injured brain

... of the brain." Flows through the surface vessels reversed and stalled, as previously observed, but ... blood to ensure a steady supply though vessels that penetrate into the brain. Shih focused ... are bottlenecks in flow." The penetrating vessels neither reversed nor stalled, even though many ...

Tiny Chemo Beads Boost Liver Cancer Outcomes

... the cancer, the microspheres get stuck in the vessels and choke off the blood supply to the tumor -- a ... beads, which expand once stuck in the vessels to better block blood flow while also delivering ... sizing, which match the small blood vessels that feed the tumors. The larger the particles ...

University of Ottawa Heart Institute Scientists Successfully Develop Novel Biomaterial to Help Grow New Blood Vessels

... Institute (UOHI) have successfully grown blood vessels in damaged muscle tissue by injecting a ... oxygen) grew a significant number of new blood vessels when treated with the biomaterial. "Our goal is ... artery disease by helping the body rebuild blood vessels and improve heart function. We see this is a ...

Two cardiovascular proteins pose a double whammy in Alzheimer's

... which work in tandem in the brain's blood vessels present a double whammy in Alzheimer's disease. ... amyloid is picked up efficiently by blood vessels that then whisk the toxic trash away. But in ... within smooth muscle cells that line blood vessels to activate genes that are necessary for smooth ...

Abbott Begins U.S. Study of XIENCE V(TM) Drug Eluting Stent Designed for Small Vessels

... for treating coronary artery disease in narrower vessels that is based on the proven efficacy, safety and ... "Treatment of lesions in small coronary vessels is often complex and associated with higher rates ... vessel) at one year. XIENCE V in Small vessels Observational data supporting the safety ...

Late-breaking data to be presented at the American Society of Hematology Annual Meeting

... a.m. "Abnormal function of the cells lining blood vessels may contribute to the complications of sickle ... endothelial dysfunction the inability of blood vessels to dilate properly in patients with sickle cell ... (a highly reactive form of oxygen) in blood vessels may decrease levels of tetrahydrobiopterin, ...

Studies examine quality of care for hospitalized sickle cell disease patients

... (a life-threatening condition affecting the blood vessels in the lungs), organ damage, and blindness. ... due to vaso-occlusion (the blockage of small vessels by sickled cells). One of these severe ... of avascular necrosis (blockage of small vessels in the bone area causing destruction to joints) ...

Employees Have Yet Another Reason To Lose Their Office Chairs In Favor Of A Treadmill Desk: Their Brain

... Desks May Increase Production of Small Blood vessels in the Brain Phoenix, ... exercise had as much as 43% more small blood vessels in their brains than those who were sedentary. ... elements including increased production of blood vessels (angiogenesis) and capillaries that assist in ...

Researchers identify how binge drinking may drive heart disease

... with fatty deposits called plaques. When blood vessels became completely blocked, heart attacks ... monocytes that can adhere to cells lining blood vessels by 700 percent," said Cullen, who led the study. ... made cultures of the cells lining blood vessels (e.g. human umbilical venous endothelial cells ...

Lactic acid found to fuel tumors

... in different ways. Tumor cells near blood vessels have adequate oxygen sources and can either burn ... lactic acid (lactate). Tumor cells further from vessels are hypoxic and inefficiently burn a lot of ... not need to reach hypoxic cells far from blood vessels and it does not need to enter into cells at all ...

Portuguese scientists discover new mechanism that regulates formation of blood vessels

... which regulates the process whereby new blood vessels are formed and wounds heal, including chronic ... therapeutic approaches to healing damaged blood vessels and building new ones. Working at the Centro ... team showed that the cells that make new blood vessels (called endothelial cells) are stimulated by an ...

Cancer researcher receives $3.8 million award from US Department of Defense

... protein that not only bind the particles to the vessels in the tumor, but they also carry the particles ... are molecular signatures in blood and lymphatic vessels (vasculature) that are specific to individual ... ways to selectively target drugs to tumor blood vessels in mice and suppress the growth of those tumors. ...
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