Sperm Cell Insights May Aid Stem Cell Research

... reduced the stem cell population in the flies' testis to zero and found that only 60 percent of testis in the genetically altered flies regained stem cells, compared with 97 percent of testis in normal flies. "We know now that in the fly ...

Penn vet researchers identify a critical growth factor that stimulates sperm stem cells to thrive

... team previously discovered that the niche in the testis of a newborn male mouse supported stem cells and ... demonstrated that it was the SSC niche in the testis that was failing in older males long before the ... of SSCs provides the foundation for testis function and fertility. Using DNA microarray ...

Living with females extends the reproductive life of the male mouse, says Penn veterinary researcher

... cells, or SSCs. Brinster's team first discovered that the niche in the testis of the newborn male mouse supports the stem cell and its differentiation ... of the stem cell. Therefore, in old males it was the SSC niche in the testis that was failing long before the SSC, which was relatively long-lived. ...

European Society for Pediatric Urology to organize anniversary congress in Amsterdam

... this CME-accredited meeting. Apart from lectures, the programme also includes panel discussions (for example about 'Hormonal aspects of undescended testis current status'), a workshop and abstract presentations. The paediatric nurses (ESPUN) offer a separate programme, including 4 sessions (Session ...

Medical imaging benefits far outweigh radiation risks

... (MOC) guarantees into every nuclear medicine professional's practice. Positron emission tomography (PET)a state-of-the-art molecular imaging testis a noninvasive, painless molecular imaging technology that allows physicians to determine how organs and tissues inside the body are functioning on a ...

One in Three Cancer Survivors on Unemployment Line

... cancer and cancers of the female reproductive organs, but unemployment rates were not higher for survivors of blood cancers, prostate cancers or testis cancers compared to controls," she added. Results of the study were published in the Feb. 18 issue of the Journal of the American Medical ...

The Obama Cancer Plan Should Prioritize Prevention, Says Cancer Prevention Coalition

... to 2005, when the latest NCI statistics were published. These include malignant melanoma (172%), Non-Hodgkin's lymphoma (79%), thyroid (116%), testis (60%), and childhood cancers (38%). As widely reported in the November 26, 2008, press, the NCI claimed that the incidence of new cancers has ...

Annual Congress European Association of Urology: highlights in Stockholm

... Peter Albers (DE)). The latter meeting will discuss techniques in organ-sparing surgery and the latest updates on chemo and radiation therapy for testis cancer. Third-day sessions will highlight current challenges in urology starting with a plenary session on the evolution of new technologies and ...

Testicular cancer gauge often not used

... Serum-based tumor markers, which are one indicator of the presence of cancer cells, are helpful in several aspects of the care of patients with testis cancer, including diagnosis, prognostication and surveillance for disease recurrence following treatment. Doctors typically rely on a series of three ...

JCI online early table of contents: March 13, 2008

... PICK: Pinpointing when you become a man Cryptorchidism, the absence in the scrotum of one or both testes (usually because of the failure of the testis to descend), and hypospadias, the abnormal positioning of the opening of the urethra, are common birth defects of the male genitalia and are risk ...

The latest about male infertility and testosterone from NewYork-Presbyterian/Weill Cornell

... to osteopenia and osteoporosis, causing weakened bones. Testosterone production is lowered when varicoceles become enlarged and twist around the testis of men. The condition can be hereditary and is found in 15 percent of all males; it also leads to a lowered sperm count and quality. Thirty-five ...

Stem cells derived from adult testes produce wide range of tissue types

... Using gene screening studies, Rafii and colleagues discovered a potential specific surface marker on SPCs. Comparison of all cells in the adult testis showed that this G-protein coupled receptor, known as GPR125, was expressed on SPCs, but not other mature germ cells. With GPR125 in hand, Rafii ...

Artificial Testis Developed by AIIMS a Boon to Suffering Patients

... success. "We are producing artificial testis and have treated over 50 patients with not a ... due to medical purposes. Though the artificial testis cannot produce sperms, yet it helps the scrotum ... said inter-sex patients have both underdeveloped testis and an ovary. "In such cases, we replace the ...

A New Research Demonstrates HIV-1 In Resident Immune Cells Of Human Testis

... A new research has found that the human testis harbors HIV-1 in resident immune cells, providing ... report by Roulet et al., “Susceptibility of human testis to human immunodeficiency virus-1 infection in ... led by Dr. Nathalie Dejucq-Rainsford examined testis tissue for the presence of HIV receptors. They ...

Carboplatin Drug Is More Effective Than Radiation Therapy For Testicular Cancer

... had fewer seminomas occurring in the remaining testis than those receiving radiotherapy. Though needing ... that it may now be safe to embark on studies of testis conservation instead of hemicastration.” (Newswise) Related information on testis Medinida: Undescended Testis: ...

Treating Testicular Cancer With A Single Dose Of Chemotherapy

... to chemotherapy also had fewer seminomas occurring in the remaining testis than those receiving radiotherapy. Though needing longer follow up and ... is the first hint that it may now be safe to embark on studies of testis conservation instead of ...

Immune System Protein Could Be the Key Infertility

... Identified more than 40 years ago, MIF plays an important role in the immune system by promoting inflammation. It is secreted by cells in the male testis and is found in seminal fluid. Past studies have found it plays a key role in sperm maturation. But MIF has also been linked to several ...

New Procedure Paves Way for Eunuchs to Choose a Gender and Conceive

... are advised to convert to males if mildly affected and females in case of severity. "They have a vaginal pouch but never a uterus. They also have testis albeit hidden and we conduct male genitoplasty surgery on such people." FPH have a lot of male hormones and look like men. Their vaginal pouch ...

Environmental Pollutants Could Impact the Size of Sexual Organs

... in their blubber. The new study reports a connection between OHC levels and reduced size of the uterus in female bears and reduced size of the testis and baculum (penis bone) in males. A large baculum is critical for successful mating in an Arctic climate, the researchers note, and even ...

Prenatal multivitamins reduce birth defects

... of cerebrospinal fluid on the brain). However, no decrease in % of Down syndrome, pyloric stenosis (which causes chronic vomiting), undescended testis or hypospadias (a malformation of the penis) cases were seen. Dr. Koren said, “It is impossible to know which vitamins and minerals are ...

Scientists Discover New RNAs in Mouse Testicles

... in the testicles, and when shut off, mice are unable to make normal sperm. The scientists pulled individual Piwi proteins out of mouse testis and checked what came along with them and found strands of the mysterious new RNAs stuck to the Piwi proteins. They have named the new ...

Pluripotent ESC, To Serve As an Effective Therapy for Many Diseases

... Irvine, California-based PrimeGen Biotech, worked with immature cells (germ cells) found in testes and ovaries. Germ cells isolated from adult human testis can be therapeutically reprogramed to have the ability to differentiate into cells that can be used therapeutically for cell-based regenerative ...

Aggression And Fatherly Behavior: Men Have It In Their Genes

... embryo should develop into a male or female formed the main focus of the study. The presence of SRY gene causes the primitive gonads to develop into testis (the male gland that produces sperms and male sex hormones). The gene is believed to be partially responsible for aggressive behavior. Behavior ...

Testicular Cancer Patients Have Improved Reproductive Outcomes After Treatment

... acquired factors is believed to play a significant role. The most common symptom associated with testicular cancer is painless enlargement of the testis accompanied by a sensation of heaviness. Self-examination plays a very important role in the early detection and treatment of testicular cancer. ...

New Treatment Option For Testicular Cancer

... trial shows that one shot of carboplatin in the short term is as safe as radiation, is less toxic, and might open the ways to using chemotherapy for testis ...