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Subcutaneous in Medical News

21st Century Obesity Pandemic Still Suffering From Effects of Tuberculosis Plague of the 1800s

... response. Fat comes in two kinds. There is subcutaneous fat stored under the skin. This is a simple bank ... said. The idea would be to send fat cells to the subcutaneous regions. That would reduce the pro-inflammatory ... stores and help reduce the burden of fat cells on subcutaneous tissue.     What are the ...

Results From Phase 1 Clinical Study of PEG-PAL in PKU and Update on Phase 2 Clinical Study

... to assess the safety and tolerability of single, subcutaneous injections of PEG-PAL in subjects with PKU. The ... were to evaluate the pharmacokinetics of single, subcutaneous injections of PEG-PAL administered at escalating ... immune response and steady state PK of subcutaneous injections of multiple dose levels of PEG-PAL. ...

SIMPONI(TM) (golimumab) Receives FDA Approval as First Once-Monthly Anti-TNF for Treatment of Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis

... First subcutaneous Anti-TNF to Launch with Three Rheumatic ... In the U.S., SIMPONI is approved as a 50 mg subcutaneous injection once a month and is indicated: ... cartilage and tissue. The first once-monthly subcutaneous anti-TNF-alpha therapy, SIMPONI is approved for ...

New drug shows promising results for psoriatic arthritis

... to be beneficial within two weeks of the first subcutaneous injection in a phase II rheumatoid arthritis ... drugs. Patients were randomized to receive subcutaneous injections of placebo, golimumab 50 mg, or ... agents that have been studied in this disease. subcutaneous administrations were well tolerated. Only a small ...

Research highlights new approaches to prevent blood clots

... to one of two treatment arms: once-daily subcutaneous injections of nadroparin (3,000 IU) or placebo. ... similar efficacy and safety between once-weekly subcutaneous injections of indaparinux with standard treatment ... thrombosis were randomized to receive weekly subcutaneous injections of 3 mg idrabiotaparinux (385 ...

New Skin Rejuvenation Discovery Receives Commercial Backing

... the RHAMM protein increases the deposition of subcutaneous fat while decreasing unhealthy visceral fat. This ... skin to replace volume lost with the decrease of subcutaneous fat that accompanies the aging process. These ... controllable re-growth of the patient's own subcutaneous fat in targeted areas to help restore a ...

Centocor, Inc. Submits Application to FDA Requesting Approval of Golimumab for the Treatment of Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis

... the approval of golimumab (CNTO 148) as a monthly subcutaneous treatment for adults with active forms of ... is being studied as an every four week subcutaneous injection and is also being studied as an ... requesting the approval of golimumab as a monthly subcutaneous treatment for the same indications. "This ...

Subcutaneous administration of an antiemetic for treating vomiting caused by chemotherapy

... The subcutaneous administration of granisetron, an antiemetic ... when injected intravenously. The advantage of the subcutaneous method is the ease of treatment for ... Home use and emergencies This is why subcutaneous administration opens new perspectives, providing ...

Modest gain in visceral fat causes dysfunction of blood vessel lining in lean, healthy humans

... internal organs -- rather than fat deposited as subcutaneous fat, just under the skin, that predicts ... and significantly increased their visceral and subcutaneous fat. In the weight-maintainer group, the ... of the study. Visceral fat gain -- but not subcutaneous fat gain -- was significantly correlated with the ...

New Survey Reveals Kidney Patients' Concern About Medicare Policies

... would not mind receiving ESA therapy by the subcutaneous (SC) route -- which would mean that ... statements that patients wouldn't mind additional subcutaneous injections. Survey comments illustrated how strongly most patients objected to subcutaneous administration of ESAs. For example, Kathe ...

Novo Nordisk Insulin Analogs Have Proven Safety Profiles

... detemir [rDNA origin] injection) is indicated for once- or twice-daily subcutaneous administration for the treatment of adult and pediatric patient with type ... may be needed in patients with type 2 diabetes. When used in an external subcutaneous insulin infusion pump, NovoLog(R) should not be mixed with any other ...

Depression linked with accumulation of visceral fat

... amount of visceral fat, it is an inaccurate measure because it includes subcutaneous fat, or fat deposited just beneath the skin. The researchers found a ... activity. The study found no association between depressive symptoms and subcutaneous fat. The findings were the same for both black and white women. Powell ...

Ferring Pharmaceuticals Announces Immediate Availability of Degarelix for the Treatment of Advanced Prostate Cancer

... cancer were randomized to either degarelix or leuprolide: a degarelix subcutaneous (under the skin) injection of 240 mg for one month with monthly ... an initial testosterone surge. Degarelix is administered monthly by subcutaneous injection. The starting dose is 240 mg, followed by monthly maintenance ...

NovaBay Pharmaceuticals Announces New Preclinical Data to be Presented at the American Academy of Dermatology (AAD) 67th Annual Meeting

... Product Candidate NVC-422 Demonstrates Ability to Treat subcutaneous Infections EMERYVILLE, Calif., March 4 /PRNewswire-FirstCall/ -- ... not only on the skin surface, but also showed potent ability to kill subcutaneous organisms by route of the hair follicles." Following are the details ...

Cynosure Obtains Favorable Markman Rulings in Patent Infringement Case Against CoolTouch

... (the 873 patent), which relates to methods for liquefying and removing subcutaneous fat cells through the use of laser energy. Cynosure is the exclusive ... in early 2007, uses a 1064 nm Nd:YAG laser to deliver energy directly to subcutaneous fat cells, causing them to rupture. The emitted fat-melting energy also ...

Juva Skin Banishes Bumps with New UniForm Cellulite Therapy Handpiece

... heat with the mechanical application allows for deep penetration into the subcutaneous tissues for much better results." UniForm was developed ... levels, while the mechanical massager stimulates circulation to subcutaneous tissues. The result is a dramatic reduction in the appearance of ....

Medarex to Receive Milestone Payment for Approval of STELARA(TM) (Ustekinumab) for the Treatment of Moderate to Severe Plaque Psoriasis

... of moderate to severe plaque psoriasis, as an infrequently administered subcutaneous injection. STELARA, generated using Medarex's UltiMAb(R) ... CNTO 148), currently under review for marketing approval as a once-monthly subcutaneous anti-TNF-alpha human antibody in the U.S. and in Europe for the treatment ...

Phase 2a Data for MEDI-528 Presented at CHEST 2008

... in Philadelphia, Pennsylvania. The presentation, entitled "Multiple subcutaneous Doses of MEDI-528, A Monoclonal Antibody Against Interleukin-9 in Mild and ... that the data demonstrate an acceptable safety profile for multiple subcutaneous doses of MEDI-528. About IL-9 IL-9 is one of at least 29 naturally ...

The missing link between belly fat and heart disease?

... in the belly around the major organs, while others received transplants of subcutaneous fat the type thats found just under the skin throughout the body. ... as the leptin-deficient mice had. Meanwhile, those that received subcutaneous fat did not experience an increase in atherosclerosis despite having ...

Immunosyn Announces the Successful Completion of First Phase 'Proof of Concept Trial' in Europe for Treatment of Diabetic Ulcers With Biopharmeceutical SF-1019

... its effect on Diabetic Polyneuropathy in Type 1 Diabetes Mellitus by both subcutaneous injection and by topical application. Regarding the "Proof of Concept ... in that a 5mm deep wound became closed, needs, as expected, unlike the subcutaneous method, more short-term development in order to improve the delivery ...

Cynosure Files Patent Infringement Lawsuit Against CoolTouch Inc.

... (the 873 patent), which covers technology using laser energy to remove subcutaneous fat. Cynosure is the exclusive licensee of the 873 patent, which is owned ... in early 2007, uses a 1064 nm Nd:YAG laser to deliver energy directly to subcutaneous fat cells, causing them to rupture. The emitted fat-melting energy also ...

Once-Weekly Exenatide Showed Statistical Superiority in Glucose Control Compared to BYETTA in Head-to-Head Study

... one or more oral antidiabetic agents. Subjects were randomized to receive subcutaneous injections of either once- weekly exenatide 2.0 milligrams or BYETTA taken ... are working together to develop exenatide long-acting release injection, a subcutaneous injection of exenatide for the treatment of type 2 diabetes based on ...

Baxter Reports Strong Third Quarter Sales and Earnings

... Halozyme's proprietary Enhanze(TM) Technology to the development of a subcutaneous route of administration for Baxter's GAMMAGARD LIQUID(TM) 10% [Immune ... using GAMMAGARD LIQUID 10% - currently administered intravenously - subcutaneous administration with Enhanze Technology may increase convenience and ...

Investigational New Drug Application for 'Fat Melting' Injections Cleared by the FDA

... Injection lipolysis involves the injection of various compounds into the subcutaneous fat, but is not currently approved by the FDA for subcutaneous injection for any purpose. "We are pleased to finally have the approval ...

Ferring Pharmaceuticals Announces Trade Name FIRMAGON(R) (degarelix for injection) for Advanced Prostate Cancer Treatment

... an established treatment for prostate cancer, FIRMAGON does not induce an initial testosterone surge. FIRMAGON is administered monthly by subcutaneous injection. The starting dose is 240 mg, followed by monthly maintenance doses of 80 mg. FIRMAGON is available for order through traditional and ...

Zogenix and Astellas Enter Exclusive Co-Promotion Agreement in the US for Newly Approved Sumavel(TM) DosePro(TM)

... needle-free delivery system. Sumavel DosePro received FDA approval in July 2009 and is a first-of-its-kind needle-free delivery system for subcutaneous sumatriptan, a treatment that provides migraine relief within 10 minutes for some patients. "Partnering with Astellas is a significant ...

Large abdominal wall lipoma causes bowel obstruction

... pelvic bone. Colon gas in the left colon shifted to the right upper side. Computed tomography (CT) of the abdomen demonstrated a large mass in the subcutaneous adipose tissue at the left lower abdominal wall. In the current case, the patient was diagnosed with Proteus syndrome based on certain diagnostic ...

Young Black, Hispanic Women Tend to Develop 'Love Handles'

... and Hispanic young adults tended to pack on both visceral adipose tissue (VAT), the fat found in the abdominal cavity around internal organs, and subcutaneous abdominal tissue (SAT), the visible, pinchable fat known as "love handles." However, the increase was notably higher in women than men. "Our data ...

FDA Approves NovoLog(R) Labeling Update

... visit www.novonordisk-us.com . (1) Revised NovoLog Prescribing Information. "Dosage and Administration." Section 2.3. "Continuous subcutaneous insulin infusion (CSII) by external pump." NovoLog(R) is a registered trademark of Novo Nordisk A/S. ...

Johnson & Johnson and Elan Corporation plc Announce Definitive Agreement for Alzheimer's Immunotherapy Program and Equity Investment

... disease. The lead compound (bapineuzumab), administered intravenously once every three months, is currently in Phase 3 clinical trials. A subcutaneous formulation, administered once a week, is currently in Phase 2 trials. In addition, a vaccine for Alzheimer's disease (ACC-001) is also under ...

New Vaccine from Intervet/Schering-Plough Animal Health is First for Canine Influenza Virus

... is intended as an aid in the control of disease associated with canine influenza virus infection, a type A, subtype H3N8. It is administered by subcutaneous injection in two doses, two to four weeks apart. It may be given to dogs six weeks of age or older and can be given annually as a component of ...

Adenoviral vector specifically targeted to EphA2 receptor in pancreatic cancer cells

... cancer was investigated on established human pancreatic cancer cell lines. Upon demonstrating specific in vitro targeting, in vivo targeting to subcutaneous growing human pancreatic cancer was tested by intravenous and intraperitoneal administration of the ablated adenoviral vector. They found that ...

Novo Nordisk Warns Customers About Stolen Insulin

... quality for our products. About Levemir (R) (insulin detemir [rDNA origin] injection) Levemir(R) is indicated for once- or twice-daily subcutaneous administration for the treatment of adult and pediatric patients with type 1 diabetes mellitus or adult patients with type 2 diabetes mellitus who ...

New Directions in Angioedema: A Focus on Etiologies and Clinical Approach

... Series for Healthcare Professionals VOORHEES, N.J., June 10 /PRNewswire/ -- Angioedema is a clinical syndrome characterized by localized, subcutaneous and/or submucosal swelling. Diagnosing the underlying cause of angioedema can be challenging, as there are multiple etiologies of this condition, all ...

Amgen's Denosumab and Eli Lilly's Forteo/Forsteo Will Drive Robust Annual Growth in the Osteoporosis Drug Market From 2013 to 2018

... to switch patients to PTH analogues and novel agents such as denosumab. The uptake of denosumab, which has a convenient dosage regimen of bi-annual subcutaneous injections, will drive the agent to achieve blockbuster sales of $2 billion in 2018 for the treatment of osteoporosis and osteopenia. The report also ...

Body Shaping Gets the Spotlight with Industry Experts and Celebrity Guest to Showcase SmoothShapes(R) and SmoothLipo(TM) Systems at THE Aesthetic Show in Las Vegas

... Photomology, to be truly successful in reducing cellulite in my patients. Photomology is a unique technology used to treat the condition and subcutaneous fat by synergistically combined dynamic laser and light energy with vacuum and mechanical massage," said Dr. Shamban. Dr. Miles Graivier ...

AIM Health Group Inc. reports largest quarterly profit since going public and announces filing of financial results for the three months ended March 31, 2009 on SEDAR

... Centres where we provide medical and complementary alternative medical care, (ii) Infusion Services where we provide intravenous infusions and subcutaneous injections to patients suffering from rheumatoid arthritis, Crohn's disease, ITP and other inflammatory diseases, (iii) Pharmaceutical Research ...

Stem Cell Study Offers Hope for Targeting Tumors

... breast and cervical cancer cells in laboratory cultures, according to British researchers. When tried on mice, the specialized cells shrunk subcutaneous breast tumors by about 80 percent, and when injected intravenously, they helped destroy about 38 percent of metastasized lung tumors in rodents. ...

NovaBay Pharmaceuticals, Inc. Reports First Quarter 2009 Financial Results

... at the American Academy of Dermatology 67th Annual Meeting that showed NVC-422 achieved significant anti-mycological efficacy in-vivo in treating subcutaneous dermatophyte infections based on an established pre-clinical model. Importantly, these data combined with the past preclinical work that showed ...

Cimzia(R) (certolizumab pegol) Now Available for Self-Administration in Adult Patients With Moderate to Severe Crohn's Disease

... who have had an inadequate response to conventional therapy. The new prefilled syringe is now available to Crohn's patients taking Cimzia(R) for subcutaneous self-administration once every four weeks after initial doses once a physician has provided instruction for proper use. The Crohn's approval ...
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(Date:7/31/2014)... the Rim Fire was in full fury, raging swiftly ... entered the backcountry of Yosemite National Park in California,s ... park, the battle began to turn, enacting a case ... combine to fuel large, severe fires. , "When the ... where fire had been used as a management tool, ...
(Date:7/31/2014)... or fat cells, are inherently different. Each of these ... own role in metabolism. In the human body, white ... primary function is energy storage. On the other hand, ... are only found in a few places in the ... type of brown adipocytes, appear mixed with brown adipocytes ...
(Date:7/31/2014)... nuts, cashews, hazelnuts, macadamias, pecans, pine nuts, pistachios and ... British Medical Journal Open (BMJ Open) (i) and ... article looked at the effects of tree nuts ... nut consumption resulted in a significant decrease in triglycerides ... article focused on the effect of tree nuts on ...
Breaking Biology News(10 mins):The Rim Fire 1 year later: A natural experiment in fire ecology and management 2The Rim Fire 1 year later: A natural experiment in fire ecology and management 3The Rim Fire 1 year later: A natural experiment in fire ecology and management 4The Rim Fire 1 year later: A natural experiment in fire ecology and management 5Hope for the overweight 2New international tree nut council study looks at nuts, diabetes and metabolic syndrome 2
(Date:7/31/2014)... THURSDAY, July 31, 2014 (HealthDay News) -- Transplant ... are red flags for burnout, a new study ... in the study reported having a low sense ... admitted to feeling emotionally exhausted, researchers found. ... specialties like transplantation," study co-author Dr. Marwan Abouljoud, ...
(Date:7/31/2014)... N.Y. (PRWEB) July 31, 2014 Joseph ... of the Hudson Valley (CDHV), a leading provider of ... the lower Hudson Valley. Dr. Lee is a ... cardiac electrophysiology. , In addition to his position ... at the New York-Presbyterian Hospital/ Columbia University Medical Center. ...
(Date:7/31/2014)... 31, 2014 Women in the Los ... of their financial future. The Independent Woman , ... registration for 6 upcoming Los Angeles area events. ... and with input from Kim Kiyosaki, a successful investor, ... Time) who is passionate about women’s financial education. , ...
(Date:7/31/2014)... rising steadily in the U.S in recent years. According ... the number of individuals reporting past year heroin use ... evidence suggests the increase may be linked to prescription ... PO use to heroin use, with POs providing the ... This drug-use trajectory appears to have become increasingly ...
(Date:7/31/2014)... Jersey (PRWEB) July 31, 2014 Clifton ... administer the application of topical fluoride treatments to their ... caries and help with tooth sensitivity in patients that ... is an infection that is commonly known as “tooth ... hard tissues of the teeth. , Fluoride ...
Breaking Medicine News(10 mins):Health News:Burnout Common Among Transplant Surgeons, Study Reveals 2Health News:ColumbiaDoctors of the Hudson Valley Welcomes Joseph M. Lee, M.D., M.S., R.P.V.I. 2Health News:ColumbiaDoctors of the Hudson Valley Welcomes Joseph M. Lee, M.D., M.S., R.P.V.I. 3Health News:The Independent Woman to Offer Financial Workshops in the Los Angeles Area - Developed by Women for Women 2Health News:NYU CDUHR researchers look at prescription opioid abuse among young adults in NYC 2Health News:NYU CDUHR researchers look at prescription opioid abuse among young adults in NYC 3Health News:NJ Top Dentists Approved, Clifton Dental Associates Now Actively Recommending the Application of Topical Fluoride Treatments to Adults 2
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