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Simplex in Medical News

Test Before Corneal Transplant May Improve Outcome

... 1 (HealthDay News) -- Among patients with herpes simplex virus who need a corneal transplant, testing for ... light for vision, can be damaged when herpes simplex virus infects the eye. In some cases, the damage ... were more likely to fail in patients with herpes simplex virus infection than in those with other eye ...

Simplex Diabetic Supply Changes Its Name to Simplex Healthcare

... simplex Diabetic Supply today announced that after only 20 months it is retiring the name simplex Diabetic Supply and will now officially be known as simplex Healthcare. Nashville, ...

Herpes: Scientists find cellular process that fights virus

... virus responsible for cold sores: Type 1 herpes simplex (HSV-1). As reported in the advance online ... of an infected cell can unmask Type 1 herpes simplex and stimulate the immune system to disintegrate ... They replicated environments when Type 1 herpes simplex thrives, namely periods of low-grade fever ...

New Hope Against the Cold Sore Virus

... Driving herpes simplex out of hiding could bring about a cure, ... of unsightly cold sores, caused by the herpes simplex 1 virus, but new research is finally offering ... say they've unlocked the mystery of how herpes simplex 1 slips into dormancy and stays dormant -- ...

Study finds genetic link to human herpes susceptibility

... probability that people who are prone to herpes simplex virus (HSV) outbreaks can inherit that ... online now. There are two types of the herpes simplex virus. Type 1 (HSV-1) is responsible for the vast ... sore at some point during their lives. Herpes simplex virus type 2 (HSV-2) is the primary cause of ...

Simplex Diabetic Supply, Inc. Secures $50 Million in Growth Equity from New Enterprise Associates

... BRENTWOOD, Tenn., Oct. 8 /PRNewswire/ -- simplex Diabetic Supply, Inc. (Simplex) has secured a ... Chip Linehan and Ryan Drant will join the simplex Board of Directors. "NEA shares our vision for ... enough to be classified as diabetes. About simplex ...

UIC joins international research effort to study autism

... families over the next three years. The initiative, called the Simons simplex Collection, is the first coordinated effort to create a database of ... eligible to participate in the study. DNA gathered through the Simons simplex Collection will be stored at a central repository. Data gathered from ...

Topical treatment for cold sores achieves efficacy of oral drugs; represents paradigm shift

... in the dermis and epidermis, where it surrounds and fuses with herpes simplex virus and disrupts the outer envelope of the pathogen," Flack said. ... so it is not absorbed into the bloodstream." Because the herpes simplex virus causes both cold sores and genital herpes, there is a strong ...

Specialized white blood cells coordinate first responders to viral infection

... looked for a role for regulatory T cells during the start of a herpes simplex virus infection in mucus membranes. When regulatory T cells are deficient in mice, the herpes simplex virus replicates rapidly in the mucus membranes and spreads to the spinal ...

Getting to the roots of hair loss

... ) from January 24 (1pm US Eastern Time). "Although Hypotrichosis simplex is very uncommon, it may prove critical in our search for an understand of ... with age, especially around the scalp. The cause of Hypotrichosis simplex in the form examined in this project is a genetic defect. It prevents ...

First Responders Acquire Revolutionary MyClyns(TM) Protective Spray

... MyClyns has also demonstrated virucidal activity against HIV-1 and Herpes simplex Virus type 1 in independent laboratory tests. "We have had an extremely ... MyClyns has also demonstrated virucidal activity against HIV-1 and Herpes simplex Virus type 1 in independent laboratory tests. MyClyns protects personnel ...

Novel vaccine concept developed by scientists at the Wistar Institute

... Institute Vaccine Center could be the answer. The secret is using a herpes simplex protein called glycoprotein D to block a specific receptor molecule on ... envelope and is expressed on the surface of cells infected with the herpes simplex virus. Glycoprotein D binds to a receptor molecule called HVEM (herpes ...

VivaGel(R) Demonstrates Anti-HIV and Herpes Activity Following Human Administration

... the results of its clinical trial demonstrating that VivaGel(R) retains antiviral activity against human immunodeficiency virus (HIV) and herpes simplex virus (HSV, the virus that causes genital herpes), following vaginal administration in women. The clinical study was conducted to assess the ...

Scientists learn why even treated genital herpes sores boost the risk of HIV infection

... New research helps explain why infection with herpes simplex virus-2 (HSV-2), which causes genital herpes, increases the risk for HIV infection even after successful treatment heals the genital skin sores and ...

Birth Control May Help Ward Off Bacterial Vaginosis

... Bacterial vaginosis is also associated with sexual activity, douching and sexually transmitted diseases, including chlamydia, gonorrhea, herpes simplex virus and HIV. Researchers aren't sure if bacterial vaginosis makes a woman more susceptible to the other infections or if the other infections ...

96-Week Safety and Efficacy Findings Presented for INTELENCE(TM) (etravirine) As Part of HIV Combination Therapy

... vs. 14 percent), nasopharyngitis (14 percent vs. 12 percent), headache (12 percent vs. 14 percent), cough (11 percent vs. 9 percent) and herpes simplex (10 percent vs. 10 percent). The incidence of nervous system and psychiatric AEs was comparable between the INTELENCE and placebo arms. ...

Condoms May Reduce Herpes Risk

... (HealthDay News) -- People who use condoms regularly can reduce their risk of getting genital herpes by 30 percent, a new study finds. The herpes simplex virus 2 (HSV-2) causes genital herpes, which is a chronic, lifelong viral infection. Although studies have found that regular condom use reduces the ...

CEL-SCI Expands Testing of Its Vaccine to Determine Efficacy Against More Virulent Strain of H1N1 Swine and Other Influenza Viruses

... constructs have already been shown to induce protection in animal challenge models against a variety of diseases such as malaria and herpes simplex virus and as therapeutic vaccines in two different autoimmune conditions. Data showed that L.E.A.P.S. vaccines were able to induce these protective ...

Man Dies of Brain Inflammation Caused by Deer Tick Virus

... ill. In general, Welch said, encephalitis cases of any sort are few, and labs are not usually able to identify the source, unless it is the herpes simplex virus. "Since no one has been testing, we really don't know the incidence of deer tick virus, but it can't be very high, because we don't have ...

Herpes medication does not reduce risk of HIV transmission

... completed international multi-center clinical trial has found that acyclovir, a drug widely used as a safe and effective treatment to suppress herpes simplex virus-2 (HSV-2), which is the most common cause of genital herpes, does not reduce the risk of HIV transmission when taken by people infected with ...

Not just a long-distance relationship: Immune cells in skin fight off infection better than the rest

... response, and the cells that remember past infections to boost the response after reinfection. They did this by using a model infection with herpes simplex virus - a virus best known for causing cold sores but also associated with life threatening diseases in certain individuals and newborns. The ...

Treatment Target for Herpes Pinpointed

... Pathogens . Herpes is transmitted by close person-to-person contact, often through the mouth or genitals. This study looks specifically at herpes simplex 1, which can cause cold sores and genital lesions. The virus can also cause stromal keritis, the leading cause of infectious blindness. After ...

Epiphany Biosciences Initiates Program to Assess Valomaciclovir (EPB-348) as Adjunctive Therapy in Multiple Sclerosis (MS)

... Valomaciclovir has been shown to possess potent antiviral activity in vitro against a number of herpes-related viruses, including herpes simplex (HSV), Epstein-Barr virus (EBV), herpes zoster (HZV), and human herpes virus 6 (HHV-6). The drug is currently being tested in a phase 2b study in ...

Singapore Gives New Sight to the Blind

... has been achieved," said Prof Tan. SJS is a life-threatening condition which is often brought on through viral infections such as the herpes simplex virus or drug allergies. It causes severe skin and mucosal blistering, especially the eyes, leading to scarring and blindness, if not death. The ...

Discovery Yields Cure for the Common Cold and the Flu

... have been working on for several years. In addition to agents that combat the common cold they have agents that combat hypertension, shingles, herpes simplex types 1 and 2 and GERD. Limited human trials of these products have been ongoing since 2006. To learn more, visit ...

AlphaVax Announces New Vice President of Regulatory, Quality and Clinical Operations

... of in-house and partnered programs. The AlphaVax technology is currently being used to advance vaccines for influenza, cytomegalovirus, herpes simplex virus, respiratory syncytial virus, a range of cancers, HIV and a number of biodefense targets. The AlphaVax headquarters and R&D facilities are ...

Poor people suffer disproportionately from chronic infections

... instance, researchers looked at H. Pylori, a bacterium that causes peptic ulcer disease; hepatitis A and B, which can cause liver disease; and herpes simplex 1 and cytomegalovirus (CMV), both implicated in cardiovascular disease, Alzheimer's disease and other ailments. Similarly, there is a large ...

Childhood Stress Compromises Immune System

... as physical abuse or time in an orphanage. Specifically, the researchers looked at levels of antibodies against the common and usually latent herpes simplex virus type 1 (HSV-1). The virus, found in about two-thirds of Americans, can cause cold sores and fever blisters. People with a healthy immune ...

In Time, Cream Might Prevent Herpes Transmission

... impact on preventing transmission." According to the World Health Organization, about 536 million people worldwide are infected with herpes simplex virus type 2 (HSV-2), the most common strain of this sexually transmitted disease. Women are much more likely than men to be infected with HSV-2, ...

Targeting Cancer's Own Stem Cells to Fight Recurrence

... protein nestin, which is a marker for nerve stem cells and is also present in neuroblastoma cells. When the stem cells were infected with a herpes simplex virus which specifically targets nestin, they did not form tumors over the next 60-day period. When infected with a different virus that does not ...

Engineered virus targets and kills apparent cancer stem cells in neuroblastoma

... neural stem cells and neuroblastoma cells both carry the protein nestin, Dr. Cripe and his colleagues tested the effect of an oncolytic herpes simplex virus called rQNestin34.5 on cells. Developed by cancer researchers Ohio State University, rQNestin34.5 carries a molecular promoter for nestin, ...

Life Sciences Discovery awards health research program grants

... product planning. Three specific vaccine projects will be initially addressed. One in five adults in Washington State is infected with the herpes simplex virus (HSV)-2. Infectious syphilis cases have doubled in the United States since 2000 and E. coli contamination continues to be a persistent ...

Peregrine Pharmaceuticals Awarded Broad New U.S. Patent for Anti-Viral Applications of Phospholipid-Targeting Antibodies

... Researchers have found that PS is exposed on the outer membrane of cells infected with HIV, influenza, hemorrhagic fever viruses, CMV, herpes simplex viruses and smallpox viruses. In addition to its potent anti-viral activity in lethal viral disease models, Peregrine's anti-PS antibody ...

Data Published in Nature Medicine Highlights Ability of Peregrine Pharmaceuticals' Bavituximab to Cure Lethal Virus Infections

... Researchers have found that PS is exposed on the outer membrane of cells infected with HIV, influenza (including avian flu), herpes simplex viruses, hemorrhagic fever viruses, measles and members of the small pox and rabies virus families. Dr. Barton Haynes, director of Duke ...

UT Southwestern researchers develop new strategy for broad spectrum anti-viral drugs

... blood-virus load. UT Southwestern researchers have found that phosphatidylserine flipping occurs in cells infected with influenza, the herpes simplex virus and viruses in the families of the small pox and rabies viruses. Other researchers have shown that this also occurs in HIV. "It could very ...

Special Purpose Needles Market to Reach $3.7 Billion by 2015, According to New Report by Global Industry Analysts, Inc

... products has expanded considerably due to increasing number of outpatient procedures. Increasing awareness of diseases such as HIV/AIDS, HCV, HBV, simplex virus, malaria, syphilis, typhus, and tuberculosis, besides new legislations dealing with worker safety are expected to spur the demand for safety ...

Herpes Suppression May Not Prevent HIV Infection

... risk of HIV-1 infection in people who have sex with men infected with genital herpes, a U.S. study finds. Previous research has shown that herpes simplex virus type-2 (HSV-2) infection -- the most common cause of genital herpes -- increases the risk for HIV-1 infection by two- to threefold. In this ...

CEL-SCI Presents Favorable Data for Leaps Vaccine Technology at Prestigious Immunology Conference

... LEAPS vaccines that were examined include one that was previously shown to provide antigen specific protection and cellular immunity against herpes simplex virus infection via interferon gamma in mouse models of human disease and another that is directed against a HIV protein. Dr. Zimmermann said: ...

NYP/Columbia physician-scientists present at ASCO 44th annual meeting

... Edwin C. and Anne K. Weiskopf Associate Professor of Medicine at Columbia University College of Physicians and Surgeons OncoVEXGM-CSF is a herpes simplex virus (a microscopic life form commonly known as the "cold-sore virus") that has been genetically changed to grow in and destroy cancer cells. The ...

Researchers explore the emerging role of infection in Alzheimer's disease

... of chronic inflammation in AD, followed by three articles presenting evidence on the involvement of spirochetes, Chlamydia pneumoniae and Herpes simplex virus type 1 in AD. These are followed by a review of amyloid proteins, which occur in many cellular forms in Eukaryotes and Prokaryotes. The ...
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