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Sequencing in Medical News

Genome of Leukemia Patient Reveals Common Mutations

... more than three years. He was selected for genome sequencing because he had typical clinical and molecular ... options, it does show the strong potential of sequencing many cancer genomes to better understand the genetic basis of cancer. "Only by sequencing complete genomes of cancer patients are we going ...

Ovarian Cancer Breakthrough Heralds New Era of Treatment

... shows the power of the new generation of DNA sequencing technologies to impact clinical medicine, and for ... granulosa cell tumors using "next generation" sequencing machines that decode billions of nucleotides at ... of the 20,000 genes in the human genome. The new sequencing technologies allow scientists to look at all at ...

J. Craig Venter Institute Awarded $43 Million, Five Year Contract From NIAID to Continue to Develop and Provide Sequencing, Genotyping, and Bioinformatics Expertise and Services in Infectious Diseases

... Institutes of Health, as one of their Genomic sequencing Centers for Infectious Diseases (GSCID). Led by ... founder and president, JCVI. "Since our first sequencing of the Haemophilus influenzae genome in 1995, to our most recent work in sequencing the isolates from the 2009 H1N1 flu outbreak, ...

City of Hope Uses Isilon IQ to Advance Fight Against Life-Threatening Diseases

... Deploys Isilon Scale-out NAS to Power DNA sequencing Workflow, Accelerating Cancer, Diabetes, and ... Isilon IQ to accelerate its next-generation DNA sequencing operations and speed time-to-results for ... in place to not only accelerate our DNA sequencing workflow, but also seamlessly expand our capacity ...

The Personal Genome Project Deploys Isilon IQ Storage to Transform Genomic Research

... Unprecedented DNA sequencing Project Deploys Isilon Scale-out NAS to Store ... continue to intensify, driven by advances in DNA sequencing chemistries, methodology, and high-throughput DNA sequencing instruments. With limited scalability and ...

Scientists From 25 Countries Sequence Cow Genome

... 300 researchers in 25 countries has succeeded in sequencing the entire genome of the placid, farm-dwelling ... and an associate professor in the Human Genome sequencing Center at Baylor College of Medicine in Houston. The information yielded from sequencing may one day even lead to a "safer" cow by ...

Covaris Introduces DNA Shearing Service

... is validated and compatible with all next-gen sequencing platforms. This process is highly reproducible ... cross contamination, which are critical for any sequencing applications downstream. "With the launch of ... a nice alternative sample prep tool for next-gen sequencing customers. In addition, Covaris is introducing ...

American Chemical Society's Weekly PressPac -- March 4, 2009

... sequencer," it could replace higher-priced sequencing techniques currently in use. The nanopore can ... the pore. Nanopores could reduce the cost of gene sequencing to $1,000 for an individual's genome, or complete ... That compares with the $100,000 to $1 million for sequencing an entire genome using conventional techniques. ...

Complete Genomes of All Known Human Rhinoviruses are Published

... First comprehensive sequencing and analysis of strains responsible for common ... well as 10 new field isolates. The whole genome sequencing and bioinformatic analyses on the rhinovirus ... exciting time in viral genomics. Next generation sequencing technology will allow researchers to study as ...

First-Ever Mapping of Cancer Patient's Genome

... director of the Washington University Genome sequencing Center, in St. Louis. "We found mutations in ... added Richard Gibbs, director of the Human Genome sequencing Center at Baylor College of Medicine, in Houston. ... University center has already started genetic sequencing of a second person with acute myelogenous ...

Researchers Find More Genes Linked to Lung Cancer

... said. "Although similar, smaller cancer gene sequencing projects have been reported, our study is the ... director of Washington University's Genome sequencing Center in St. Louis, said during a Tuesday teleconference. The research, known as the Tumor sequencing Project, has important implications for the ...

15 human genomes each week

... that our rapid adoption of next-generation sequencing technologies has been so successful in driving ... research," says Dr Harold Swerdlow, Head of sequencing Technology at the Wellcome Trust Sanger ... are important for human disease. Next-generation sequencing is also enabling the Institute's own research ...

3 sequencing companies join 1000 Genomes Project

... firms that have pioneered development of new sequencing technologies have joined the international effort ... work is being done by the institute's Large-Scale sequencing Network, which includes the Human Genome sequencing Center at Baylor College of Medicine, Houston; ...

Scientists confirm new virus responsible for deaths of transplant recipients in Australia

... In the first application of high throughput DNA sequencing technology to investigate an infectious disease ... liver and kidneys was analyzed using rapid sequencing technology established by 454 Life Sciences and ... existing screening methods. High throughput sequencing and methods for cloning nucleic acids of ...

Project Will Map Genomes of 1,000 People Worldwide

... years ago. Today, thanks to amazing strides in sequencing technology, bioinformatics and population ... have to use expensive and time-consuming DNA sequencing to help them identify precise genetic variants ... of a population. By harnessing the power of new sequencing technologies and novel computational methods, we ...

International consortium announces the 1000 Genomes Project

... Project, an ambitious effort that will involve sequencing the genomes of at least a thousand people from ... years ago. Today, thanks to amazing strides in sequencing technology, bioinformatics and population ... those studies with costly and time-consuming DNA sequencing to help pinpoint the precise causative variants. ...

Johns Hopkins to participate in 1000 Genomes Project

... Project, an ambitious effort that will involve sequencing the genomes of numerous people from around the ... project will home in on these differences. By sequencing the genomes of at least 1,000 people, the project ... Institute. By harnessing the power of new sequencing technologies and novel computational methods, we ...

The Top 10 Health Stories of 2007, From the Editors of the Harvard Health Letter

... infection, to name a few examples. 3. Genome sequencing in a jiffy--and cheap. sequencing a genome -- identifying all the chemical base ... a single sequence. Within a decade, the price of sequencing a genome may drop to $1,000, say some experts. ...

Photo: Scientists Complete Genome Sequence of Fungus Responsible for Dandruff, Skin Disorders

... skin conditions in humans. Results of the genome sequencing are published in today's online edition ... the presence of M. globosa. "A complete genomic sequencing of a Malassezia genome opens ... molecular level before this research. The genetic sequencing of M. globosa has expanded the range of ...

Baylor College of Medicine increases fleet of Roche Genome Sequencer FLX Systems to 10 instruments

... INDIANAPOLISThe Human Genome sequencing Center at Baylor College of Medicine boosted its sequencing capabilities with an agreement to acquire seven ... 10 Genome Sequencer FLX Systems, the Human Genome sequencing Center will be in a unique position to apply 454 ...

454 Sequencing(TM): Science Paper Describes a Novel, Highly Efficient Method of Sequencing Ancient DNA; Sequences the Mitochondria of 10 Individual Mammoths to Prove It

... The study, entitled "Whole-Genome Shotgun sequencing of Mitochondria from Ancient Hair Shafts" appears ... of mammoths. "The challenge with sequencing ancient DNA is finding an undamaged and uncontaminated sample, and having a sequencing technology that can produce long, highly accurate ...

TGen-led team is 1 of 7 selected for $1 million skin-cancer grants

... We will also work towards identifying additional susceptibility genes by sequencing the entire genomes of patients from five of the largest melanoma families. ... Institute Dan Gioeli, Ph.D., University of Virginia Proposal Title: sequencing of the Melanoma Exome, Transcriptome and Epigenome Principal ...

Swine Flu Genes Went Undetected for Years: Report

... sequencing of virus' genome should make finding a vaccine easier, CDC says ... viruses than we do for typical seasonal influenza viruses," she said. sequencing the virus' genetic code is also important for planning the public health ...

MMRF and the Broad Institute to perform whole genome sequencing of multiple myeloma samples

... uncover the molecular changes underlying multiple myeloma by whole genome sequencing of individual patient tumors. The MMRF will provide both patient samples ... said Stacey Gabriel, PhD, Co-Director of the Broad Institute's Genome sequencing and Analysis Program. "This exciting collaboration with the MMRF will ...

Ambry Genetics Announces Illumina CSPro Certification for GA Sequencing

... on the Illumina GA systems since January 2008. We are offering standard GA sequencing services to pharma, clinical and academic research groups, while keeping ... now a Certified Service Provider able to offer Illumina Genome Analyzer sequencing services using Illumina technology. Now that Ambry Genetics is a global ...

Quest Diagnostics Discovers New Genetic Mutations Affecting Cystic Fibrosis Screening

... lead investigator of the study. "Comprehensive mutation analysis using DNA sequencing and exon deletions/duplications is therefore important to resolve apparent ... test, which enables physicians to identify rare mutations that cause CF by sequencing the complete coding sequence of the cystic fibrosis gene. About ...

Mayo clinic study finds gene bringing together animal and human research in alcoholism

... of the MPDZ gene in humans. It is also a very long gene and its sequencing required considerable effort and costs. To investigate the relevance of ... new, mostly rare variants were discovered in the human MPDZ gene. sequencing allowed the first opportunity of comparing the MPDZ gene in humans and ...

Mayo Clinic Study Finds Gene Bringing Together Animal and Human Research in Alcoholism

... of the MPDZ gene in humans. It is also a very long gene and its sequencing required considerable effort and costs. To investigate the relevance ... new, mostly rare variants were discovered in the human MPDZ gene. sequencing allowed the first opportunity of comparing the MPDZ gene in humans and ...

'Personalized' genome sequencing reveals coding error in gene for inherited pancreatic cancer

... at the Johns Hopkins Kimmel Cancer Center have used "personalized genome" sequencing on an individual with a hereditary form of pancreatic cancer to locate a ... genes and compares the changes to those found in healthy people. "Gene sequencing has always had the potential to help us learn if a person is susceptible ...

EMBL GeneCore purchases Genomatix's next generation sequencing data analysis solution

... leading provider of complete solutions for the analysis of Next Generation sequencing (NGS) data, announced today that the European Molecular Biology Laboratory ... for input of raw sequence reads plus optional quality files from any deep sequencing hardware. It provides ultra fast mapping of sequences of any length ...

BioNanomatrix Appoints Gary Zweiger, Ph.D., as Vice President of Business Development

... project in partnership with Complete Genomics Inc. for very low-cost sequencing of the human genome. "This is an exciting time to join ... to the financial community. He has published a general audience book on sequencing the human genome, authored numerous scientific publications and holds ...

Antibiotics can cause pervasive, persistant changes to microbiota in human gut

... which was used in this study, characterizes microbial populations by sequencing short, hypervariable regions of one gene common to all microbes, the 16S ... richness in microbial samples at a fraction of the cost of traditional sequencing technologies. ...

Desert plant may hold key to surviving food shortage

... crops such as wheat. Scientists will use the latest next-generation DNA sequencing to analyse the plant's genetic code and understand how these plants ... The genetic code of the plant will be deciphered using a DNA sequencing machine that uses an enzyme found in fireflies as a flash light to help ...

Researchers Publish Genome Sequence for Duck-Billed Platypus

... K. Wilson, director of Washington University School of Medicine's Genome sequencing Center, said in a prepared statement. "Now, we'll be able to pinpoint ... co-exist in the same genome," Adam Felsenfeld, head of the Comparative and sequencing Analysis Program in NHGRI's Division of Extramural Research, said in a ...

Leading HIV researchers to collaborate on vaccine development

... improved vaccine candidates: Identification and full-length genetic sequencing of newly transmitted viruses Clarifying the impact of human genetics ... contribute unique resources. For example, CHAVI supports high-throughput sequencing technology that can reveal tiny mutations in the ever-changing virus, but ...

Prix Galien USA Welcomes Eighth Nobel Laureate to its Prestigious Award Committee

... for Chemistry after developing a technology that greatly expedited DNA sequencing and helped open doors for today's techniques that allow the sequencing of entire genomes, including the human genome. Gilbert also co-founded ...

VBI, Mayo Clinic investigate link between fungal proteins, innate immunity and asthma

... in Alternaria biology and principal investigator of the Alternaria genome sequencing project funded by the National Science Foundation-United States Department of Agriculture (NSF-USDA) Microbial Genome sequencing Program, stated: Our part of the collaboration is critical and will ...

Evolutionary history of SARS supports bats as virus source

... data on coronaviruses, and Janies said only through the discovery and sequencing of even more viruses can the complete SARS story be told. We dont fully ... out of the wild again. SARS has opened our eyes to other kinds of viruses. sequencing of more coronaviruses in exotic animals will teach us about their ...

Genomatix takes a lead in Next Generation Sequencing

... in collaboration with customers, successfully analyzing Next Generation sequencing data (from 454 and Solexa) have firmly established that ElDorado brings a ... including Digital Gene Expression (DGE) Studies as well as Chip sequencing (ChiPSeq) Assays. Inquiries are welcome. ...

Cold Spring Harbor scientists devise novel, low-cost method of sifting genome's high-value regions

... McCombie, Ph.D., a molecular biologist who heads the Laboratorys gene sequencing center, sought an efficient way of separating whats most valuable in the ... genomic code culled from relatively small, focused areas as opposed to sequencing the entire genome and only afterward honing in on areas of interest. ...
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