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Rhesus in Medical News

Reduced diet thwarts aging, disease in monkeys

... expanded in 1994 with the addition of 46 more rhesus macaques. All of the animals in the study were ... table, and 20 are on a calorie-restricted diet. rhesus macaques have an average life span of about 27 ... ranging from spiders to humans The Wisconsin rhesus macaque study, however, is likely to provide the ...

Press Releases on BPA Studies By-Pass Scientific Process

... of Calcium Handling," Scott M. Belcher, PhD; and "Oral Exposure of Female rhesus ... Frederick vom Saal, PhD. The statement can be attributed to ... of health risks. "Most notably though, the study presented on rhesus monkeys appears to confirm that bisphenol A is efficiently converted after ...

Yerkes researchers find link between psychological stress and overeating

... Research Center, Emory University, have found socially subordinate female rhesus macaques over consume calorie-rich foods at a significantly higher level ... To do this, they studied the feeding patterns of socially housed female rhesus macaques, which are organized by a dominance hierarchy that maintains ...

OHSU is part of national effort to preserve, restore fertility in women with cancer

... working on methods for restoring fertility in cancer patients by studying rhesus macaque monkeys who have reproductive systems very similar to humans. ... Nature demonstrating great strides in re-establishing fertility in a rhesus macaque monkey after ovarian tissue transplantation that resulted in a ...

Monkey Moms Use Baby Talk, Too

... Aug. 24 (HealthDay News) -- When interacting with their infants, female rhesus monkeys use special vocalizations similar to the "baby talk" used by human ... he said. The researchers studied vocalizations among adult female rhesus macaques on an island off the coast of Puerto Rico. When a baby was ...

Lighter Meals May Bring Longer Life

... many diseases in yeast, worms, flies and, as Sierra pointed out, in some strains of mice. The new, two-decade-long study ultimately involved 76 rhesus monkeys, all of whom started the study as adults (aged 7 to 14 years). Thirty-three monkeys are still alive, 13 of whom are allowed to eat as they ...

Transplant drug stimulates immune memory

... Larsen, MD, PhD, director of the Emory Transplant Center and chair of the Department of Surgery, to show that rapamycin had similar effects in rhesus macaques infected with vaccinia virus as in mice. That research was conducted at Emory's Yerkes National Primate Research Center. Rapamycin, also ...

Studies Report More Harmful Effects From BPA

... said Steve Hentges, executive director of the Polycarbonate/BPA Global Group at the American Chemistry Council. "Most notably though, a study on rhesus monkeys appears to confirm that bisphenol A is efficiently converted after oral exposure to biologically inactive metabolites, which are then rapidly ...

Why Chimps, Monkeys Don't Develop Alzheimer's

... in live human brains, thus "lighting up" the plaques on positron-emission tomography (PET) scans. They used PIB in brain tissue from nine deceased rhesus monkeys, six deceased squirrel monkeys, three deceased chimpanzees, nine deceased humans with end-stage Alzheimer's and three deceased older but ...

Germicide Might Guard Against HIV Infection

... Patrick M. Schlievert, a professor of biology at the University of Minnesota. In the new study, researchers tested the compound on five female rhesus macaques that were vaginally exposed to the monkey equivalent of the AIDS virus. The findings were published in the March 4 online issue of Nature . ...

OHSU vaccine research targets HIV in the slower, early stage of infection

... programmed to express SIV proteins and trigger specialized effector memory T-cells to look for and attack SIV in its early stages. In total, 12 rhesus macaque monkeys at the Oregon National Primate Research Center were vaccinated using this method. When the animals were later infected with SIV, ...

Growth factor protects key brain cells in Alzheimer's models

... and animal models, including transgenic mouse models of Alzheimer's disease; aged rats; rats with induced damage to the entorhinal cortex; aged rhesus monkeys, and monkeys with entorhinal cortex damage. In each case, when compared with control groups not treated with BDNF, the treated animals ...

Brain Protein May Have Potential Against Alzheimer's

... animals receiving the treatment -- transgenic mouse models of Alzheimer's disease, aged rats, rats with induced damage to the entorhinal cortex, aged rhesus monkeys and monkeys with entorhinal cortex damage -- also showed long-term benefits. They began producing more BDNF on their own and exhibited better ...

Researchers at Columbia University Medical Center link blood sugar to normal cognitive aging

... animal studies helped confirm the relationship between glucose and dentate gyrus activity; the researchers found the same association in aging rhesus monkeys and in mice. "Beyond the obvious conclusion that preventing late-life disease would benefit the aging hippocampus, our findings suggest ...

Possible AIDS Treatment Shows Promise in Monkeys

... 10 (HealthDay News) -- Researchers report that a treatment under development appears to stop the equivalent of the AIDS virus in monkeys. Nine rhesus macaque monkeys infected with a virus known as SIV underwent treatment and remain alive eight months later. The treatment appears to work by ...

Researchers find stem cells from monkey teeth can stimulate growth and generation of brain cells

... and craniofacial cells. Yerkes researcher Anthony Chan, DVM, PhD, and his team of researchers placed dental pulp stem cells from the tooth of a rhesus macaque into the hippocampal areas of mice. The dental pulp stem cells stimulated growth of new neural cells, and many of these formed neurons. "By ...

Anxiety, Shyness May Be Long-Lasting Traits

... the University of Wisconsin School of Medicine and Public Health. They studied brain activity, anxious behavior and stress hormones in adolescent rhesus monkeys. Those with the most anxious temperaments showed higher activity in a part of the brain called the amygdala, which regulates emotion and ...

JCI table of contents: June 20, 2008

... of this study should help researchers identify this protein. TITLE: Measles virus blind to its epithelial cell receptor remains virulent in rhesus monkeys but cannot cross the airway epithelium and is not shed AUTHOR CONTACT: Roberto Cattaneo Mayo Clinic, Rochester, Minnesota, USA. Phone: ...

Measle's Spread Doesn't Depend on Airways

... measles in monkeys." The team demonstrated its theory by developing a measles virus that cannot enter the airway epithelium. They then infected rhesus monkeys with the virus via the nasal passages. The monkeys developed a rash and lost weight consistent with measles infection; however, tests ...

Gay Men, Straight Women Have Similar Brains

... homosexuality, the researchers said. Experts have also speculated that exposure to sex hormones prenatally influence sexual preference. Male rhesus monkeys have more androgen (a male sex hormone) receptors in the right side of the brain, while females have an equal distribution of receptors for ...

Monkey Controls Robotic Arm With Brain

... of movement control, the researchers inserted probes the width of human hairs into approximately 100 neurons located in this brain region in two rhesus monkeys. The probes were then linked directly to a computer outfitted with a complex piece of software capable of reading and expanding upon the ...

Researchers develop first transgenic monkey model of Huntington's disease

... to relieve symptoms. Death typically occurs 15 to 20 years after onset. This study marks the first time that researchers have developed a rhesus macaque model of a specific human disease using transgenic technologies, a marked improvement over mouse models. Transgenic animals are created using ...

Monkey Brain Gives Clues to Human Interaction

... people with autism, a social/learning disorder that affects more than one million Americans. "Our prior studies described how social attention of rhesus monkeys is similar to humans -- motivated by status and sex, and sensitive to the attentive states of other individuals," Michael Platt, an associate ...

Prenatal exposure to maternal antibodies linked to autistic behaviors in offspring

... in children with autism. To test this hypothesis, Amaral and his research team at the California National Primate Research Center exposed eight rhesus monkeys to human IgG at three times during the end of the first trimester of pregnancy. Four monkeys received IgG from mothers of children with ...

Evolution of human genome's 'guardian' gives people unique protections from DNA damage

... genes involved in DNA metabolism or repair to be mostly unique in humans. While the functional ability of some genes is shared with chimpanzees and rhesus monkeys, researchers said DNA metabolism and repair function it is not shared at all with rodents. In humans, when DNA damage is detected, the p53 ...

amfAR announces inaugural Mathilde Krim Fellowship Awards for AIDS research

... most other animals cannot be infected with HIV. Dr. Diaz-Griffero plans to determine whether one such infection-blocking protein, TRIM5alpha from rhesus monkeys, can block the successful completion of HIV infection not only before but after the virus converts itself to DNA. Understanding the various ...

Cross-species transplant in rhesus macaques is step toward diabetes cure for humans

... stages of developing into pancreatic tissues. Within several weeks of the transplants, the cells became engrafted, or established, within the three rhesus macaque monkeys that received them. The cells also released pig insulin in response to rising blood glucose levels, as would be expected in healthy ...

Estrogen Therapy Protects Against Fading Mental Powers: Study

... estrogen, or estradiol, on a group of four rhesus monkeys, whose menstrual cycle and menopause are ... divided them into four groups: two with young rhesus monkeys, two with older monkeys. One ... story in the older animals. The older rhesus monkeys that got the estrogen boosters performed ...

Human Uterine Transplant In Near Future

... successful transplant on a non-human primate, a rhesus monkey, last month by a team of researchers from ... oncology, has performed a transplant in a rhesus monkey along with colleagues at Pittsburgh ... function properly by following a pregnancy in a rhesus monkey to term, even though this further test is ...

An abused child may grow up to be an abusive parent

... of Chicago. //This study was conducted on baby rhesus monkeys. Infant abuse in early stages of life ... The research team found that when baby rhesus monkeys endured high rates of maternal rejection ... Systems and Adult Abusive Parenting in rhesus Macaques" published in the current issue of ...

Chronic binge drinking can hasten HIV development

... simian immunodeficiency virus (SIV) among rhesus macaques. The same may be the case in humans ... progression. For this reason, we adopted the rhesus macaque SIV model of HIV disease in order to more ... study authors administered alcohol to 16 male rhesus macaques for five hours on four consecutive days ...

NHGRI Aims To Sequence Primate Genomes

... including the chimpanzee (Pan troglodytes), the rhesus macaque (Macaca mulatta), the orangutan (Pongo ... similarities with humans. For example, the rhesus macaque is an essential research model for drug ... to the human immunodeficiency virus (HIV), the rhesus is widely recognized as the best animal model for ...

Nepali Rhesus May be Used as an Alternate for HIV/AIDS Research

... Scientists have found that Nepali rhesus is by all means a suitable alternate for the ... macaques are more closely related genetically to rhesus macaques from India than rhesus macaques of China. This is important ...

Monkeys offer genetic clues to adult blindness

... A genetic link between rhesus monkeys with macular degeneration and humans// ... age-related macular degeneration in humans and rhesus monkeys. This discovery, Dawson said, would help ... Dawson said. Unlike most other animals, a rhesus monkey's eyes have the same complex structure as ...

New Approach to Routine Prenatal Genetic Testing

... Sequenom expects a non-invasive application of its technology for fetal rhesus D (RhD) typing to become available in these laboratories beginning in the first half of 2007. rhesus disease can occur when the blood of the expectant mother is incompatible ...

Limited Calorie Intake Holds the Key to Delay Ageing

... Recent research done on rhesus monkeys shows that ,limiting calorie intake may actually help increase ... improve the functioning of important defensive cells in the immune system. rhesus monkeys are said to be closely akin to human beings in their immune ...

Ancient Ancestors Might Have Had a Clue to HIV

... broad category as HIV. But each species makes a slightly altered version, making them immune to different combinations of such viruses. The type that rhesus macaques produce, for example, confers complete resistance to HIV; the sort made by baboons slows that viruss replication by 50-fold. In ...

Surgeons Gear Up To Carry Out First Womb Transplant

... apparently received ample prospective donors. Recently in October, Dr Del Priore's team was happy with the womb transplant they performed on a rhesus monkey. The monkey was observed for 20 hours, with the new womb receiving adequate blood supply and the monkey coping well with the new entrant. The ...

Researchers explore medicine in space

... most surgeries. Prior to UF's study, the only real data showing how weightlessness affects general anesthesia, came from a mission in which two rhesus monkeys were sent to space. When the monkeys returned to Earth, surgeons performed minor biopsies on them as part of their study. One of the monkeys ...
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