Progress Reported Against Gene Involved in Hepatitis C
... (HealthDay News) -- Nearly 100 genes that support replication
of the hepatitis C virus (HCV) in the human body ... that blocking several of the genes suppressed replication
of the virus.
"We may be a few years away from ... of cellular vesicles and plays a role in the replication
of poliovirus, the researchers said.
They also ...
Birdstep Technology Announces The Dual Upcoming Release Of Its Raima Database Manager Products
... will extend RDM's high availability by providing replication
between RDM Embedded databases and RDM Server ... all the way up to Enterprise databases. The new replication
feature provides support for multiple RDM Embedded database instances to perform one way replication
into a RDM Server database. The RDM Server ...
Compounds that trigger beta cell replication identified by JDRF funded researchers
... one of the two appears to promote beta cell replication
via a biological pathway known to be critical for ... molecules that induce functional beta cell replication
using high throughput screening approaches. We ... as well as to show effects on human beta cell replication
JDRF's Regeneration research ...
Burnham researchers illuminate mechanisms that regulate DNA damage control and replication
... (Ddk) in monitoring damage control during DNA replication
and reinitiating replication
following DNA repair. Since Ddk is often ... 24 issue of Molecular Cell .
Accurate DNA replication
is essential for maintaining the stability of the ...
Study first to show that RNA interference can facilitate vaccine development
... small interfering RNA (siRNA) drug can reduce the replication
of respiratory syncytial virus and reduce the ... in the mice.
Tripp pointed out that RSV replication
was reduced in a dose-dependent manner, meaning ... administered. He said it's possible to halt viral replication
entirely with higher doses of the drug, but that ...
Selenium may slow march of AIDS
... that contain selenium negatively affects the replication
of HIV," said K. Sandeep Prabhu, Penn State ... "Our results suggest a reduction in viral replication
by at least 10-fold."
Selenium is a ... that the addition of selenium inhibits the replication
of HIV at least 10-fold, compared to cell ...
Existing anti-obesity drugs may be effective against flu, hepatitis and HIV
A Thousand-fold Reduction in Viral replication
In their experiments, Munger and colleagues ... enveloped viruses, the team measured influenza A replication
in the presence of the same TOFA and FAS ... 96 hours. They found that the drugs blocked HCMV replication
without causing cell toxicity or self-destruction ...
A potential approach to treatment of hepatitis B virus infection
... the activation of the DNA damage pathway by viral replication
for the generation of antiviral drugs needs to be ... prevention of viral integration inhibits viral replication
and promotes cellular apoptosis. Thus, the ATM-specific inhibitor ku55933 can inhibit HIV replication
in primary T cells.
Despite the availability ...
Scripps research team unravels new cellular repair mechanism
... which cells prepare to replicate DNA, to actual replication
during the S phase. Now, in the new paper, the ... met.
However, if a problem arises in the DNA replication
process during the S phase, the entire process ... genes during S phase. Because those genes encode replication
and repair enzymes, re-expression of the G1 genes ...
Tufts researchers discover link between DNA palindromes and disease
... scientists have discovered that slow or altered replication
causes chromosomal breaking. But why does DNA replication
In a Tufts University study published ... peculiar DNA sequences named palindromes and replication
Sergei Mirkin, White Family Professor ...
New agent strikes at respiratory syncytial virus replication
... two, designated AUG-2, significantly reduced RSV replication
in both cell culture and mouse experiments.
is one of the major pathogenetic processes of ... it replicates, Garofalo said. So stopping viral replication
would be a very important part of any therapeutic ...
Scripps Florida scientists develop a process to disrupt hepatitis C virion production
... the assembly pathway. Total disruption of the replication
process would be a cure for the disease, he adds, ... requires the normal cellular machinery for its replication
and has developed strategies to utilize normal ... The requirement of domains I and II for RNA replication
is well documented. NS5A domain III, however, is ...
EMC Extends Innovation for VMware environments
... virtual machines. -- Application-Integrated replication
leveraging Exchange, SQL Server, Oracle, and ... supported in VMware environments using EMC replication
Manager. -- Storage resource management that ... with EMC's broad portfolio of remote replication
including EMC SRDF(R), EMC ...
AMAS Test Measures Lethal Replikin Gene Activity in Lung and Other Cancers
... Dec. 6 /PRNewswire/ -- A gene related to rapid replication
lethality has been found to be present in, ... been previously determined to be
related to rapid replication
and virulence. Using proprietary ... are evidently related to the rate of replication
in the cancer. In
short, the AMAS test measures ...
Health and Pension Benefits Provider Turns to Xiotech's TimeScale Replication Services to Protect Critical Data
... Cost-Effective, Highly Available and Secure Data
for United Mine Workers of America Health and ... information by providing automated, long-distance replication
critical customer-specific data to a secure ... in the event of a natural disaster. "TimeScale replication
Services is ideal for midsized organizations
Chromatin remodeling complex connected to DNA damage control
... was blocked, the cells' response to replication
stress was impaired, greatly slowing down replication
in the absence of another replication
checkpoint factor called Tof1.
Shen discovered ...
Immune Response May Speed AIDS Progression in Women
... General Hospital.
"Focusing on immune activation separately from viral replication
might give us new therapeutic approaches to limiting HIV-1-induced ... resulting in lower levels of HIV-1 replication, persistent viral replication
and stronger chronic immune activation can lead to the faster progression ...
Damon Runyon Cancer Research Foundation awards prestigious fellowships to 17 top young scientists
... the mechanism of a new drug called Triapine, which may prevent the replication
of tumor cells and is currently being tested in Phase II and III clinical ... of the genome. Identifying genes involved in the regulation of DNA replication
is critical for understanding how a normal cell can become a tumor cell. ...
Lethality of H1N1 Influenza Virus Increasing According to Latest Replikin Analysis of Virus Peptide Genomic Data
... discovery of Replikins, a new group of peptides related to the rapid replication
function in viral and other diseases. The company has designed unique ... on the company's discovery of a new group of peptides related to rapid replication
called Replikins, whose increase in concentration in virus or other ...
Children's Hospital Boston Deploys AutoVirt Solution to Increase Speed and Efficiency of Windows Data Replication
... in order to increase the speed and efficiency of its Windows data replication
operations. Since its deployment, AutoClone has helped the Children's ... Handling: AutoClone records an accurate and detailed log entry while the replication
process continues, uninterrupted.
Destination Share Support: ...
iMedica Launches Transition™, a New, Streamlined EHR That Breaks Down the Barriers to Physician Adoption and Use
... paper records continue to disappear in favor of electronic records, data replication
ensures accuracy and security. Low Costs: Transition costs about ... note documentation, a traditional barrier to EHR acceptance. iMedica's replication
technology enables backup, recovery and accessibility, as well as ...
New HIV Drug May Help Those Resistant to Therapy
... Study in monkeys finds that it reduces replication
of the virus,,,,
WEDNESDAY, April 1 (HealthDay News) -- An ... disease can only progress if the virus is replicating, so if we can slow replication
down, we can reduce the impact of the disease on the patient's life," ...
Penn Medicine presents HIV gene therapy trial data at CROI 2009
... in the gut with VRX496 modified cells, which is a major site of HIV replication
and suggests that the modified cells are going where they need to go," ... for adverse events, viral load, CD4+ T cell count, vector-derived replication
competent lentivirus (RCL) and immunogenicity, vector DNA integration ...
Penn study identifies how ebola virus avoids the immune system
... "Tetherin is the first example of a protein that affects the virus replication
cycle after the virus is fully made and prevents the virus from being able ... allowing the cell's natural defense systems to slow down viral replication
and give the animal or person a chance to mount an effective antiviral ...
Helicobacter pylori can multiply in autophagic vesicles
... and subsequent adoption of these autophagic vesicles by H. pylori for replication
in macrophages. The fate of H. pylori is dependent on the strains ... of intracellular microorganism because it can invade host cells to undergo replication
within the autophagosome. The bacterium's residence inside infected cells ...
High insulin levels raise risk of breast cancer in postmenopausal women
... now needs to focus on ways to reduce insulin's effects on cell growth and replication
in the breast while preserving its positive metabolic effects.
There ... on how the effects of insulin and insulin-like growth factors on cell replication
and survival influence a variety of conditions. "Every cell in the body ...
5 Brown faculty elected to world's largest scientific body
... for her ongoing research. Her lab is studying the initiation of DNA replication
(doubling of the hereditary information of the cell), and has devised a method to map the start site of DNA replication
at the nucleotide level. Her research in progress suggests that a steroid ...
Does HBV infection induce acute cellular DNA damage?
... (ATM) pathway and ATM-Rad3-related (ATR) pathway. Virus replication
presents the host cells with large amounts of exogenous genetic material, ... DNA ends and unusual structures. Therefore, infected cells recognize viral replication
as a DNA damage stress and elicit DNA damage signal transduction, which ...
deCODE Launches deCODE BreastCancer(TM), a Genetic Test to Screen for Risk of the Common Forms of Breast Cancer
... percent of all breast cancers. The test
integrates data from discovery and replication
studies published in major
peer-reviewed journals and involving nearly ... of European
descent. deCODE and other organizations are conducting replication
to validate these markers in populations of other continental ...
Pitt research indicates new virus is culprit, not bystander, in deadly skin cancer
... propose two possible reasons why these mutations develop: If viral replication
continues, the immune system could recognize the intruder to eliminate diseased cells, or the viral replication
itself will lead to the death of the cancer cells. Both of these ...
New approach, old drug show promise against hepatitis C, Stanford research shows
... could hinder that protein, resulting in a tenfold decrease in virus replication
with no apparent harm to infected liver-like cells. Because the drug has ... the virus' process of binding RNA. This is a necessary step in the virus' replication
process and, through careful observation, the team determined where it ...
H5N1 Virus Replikin Gene Counts Indicate a New More Virulent Influenza Cycle Has Begun
... Health Organization. Replikins, Ltd then reported that the cycle of rapid replication
for H5N1 which began in 1996 appeared to be over in 2006 ---"until the next rapid replication
cycle of this or another influenza virus strain begins".
Potential viral therapy weapon for difficult cancers is safe and effective in study
... wild-type HSV-1 virus. Over a 72-hour period, researchers noted a robust replication
of the wild-type HSV-1 in these cells, but in cells injected with rRp450, the replication
rate was inhibited 10,000 fold with no signs of productive virus ....
OSMA Launches EMR Standards of Excellence Program
... chart at the speed-of-thought,
code, and bill immediately. Robust replication
functionality enables access
to information anytime anywhere regardless of ... recovery and preparedness functionality alleviates concerns via
and iMedivault(TM) Portal services. Our template free
design allows ...
Human, animal vaccine development goal of hepatitis E virus research
The first NIH grant, entitled Mechanism of hepatitis E virus replication
and pathogenesis, conveys total funding of $1,561,797 and the ... enable researchers to learn more about the molecular mechanisms of HEV replication
and pathogenesis by using pigs and chickens as animal model systems. ...
Mass. General Hospital receives Gates Foundation grant to expand HIV controllers study
... discovering information that can guide design of a vaccine to limit viral replication
in HIV-infected individuals. A primary focus will be understanding ... latest technology to analyze which immune responses best suppress viral replication
and investigate how the virus evolves to escape the immune system, ...
HIV persists in the gut despite long-term HIV therapy
... one reason the virus persists in the blood is because of ongoing cycles of replication
in the GALT. The authors conclude that any possibility of further lowering ... more powerful drug regimens to stop the low levels of ongoing viral replication
originating in the GALT. The development of such regimens is an important ...
Veterinary researchers study poultry virus as human cancer treatment
... system that activates upon infection with the virus, thereby preventing replication
of the virus, explains Subbiah. Cancer cells, however, have defective ... these defects to replicate specifically in the diseased cells. The replication
of the virus generates apoptosisalso known as programmed cell death or ...
Ninety-one Percent of BARACLUDE(R) (entecavir) Treated Patients in a Four-Year Cohort Demonstrated Virologic Suppression to Undetectable Levels
... B infection. HBeAg is a
viral protein identified as a marker of active replication
of the hepatitis
B virus. Patients in this cohort were initially treated ... hepatitis B virus infection in
adults with evidence of active viral replication
with either evidence of
persistent elevations in serum aminotransferases ...
Researchers Identify New Method to Selectively Kill Metastatic Melanoma Cells
... death specifically in melanoma cells. Fisher said that mda-5 is a key regulator of innate immunity that induces interferon beta production limiting replication
of specific pathogenic viruses.
This work was supported by grants from the National Institutes of Health, the Spanish Ministry of Science and ...