Study identifies causes of bone loss in breast cancer survivors

... calcium excretion in urine and an overactive parathyroid gland. "Doctors evaluating breast cancer ... patients. And in 5 percent of patients, the parathyroid gland was overactive, producing a hormone that ... Camacho said. There are various treatments for parathyroid gland disorder, depending on its cause. In ...

Too much calcium in blood may increase risk of fatal prostate cancer

... strongly associated with it, such as high serum parathyroid hormone, increases the risk for fatal prostate ... that reduce serum levels of calcium and/or parathyroid hormone." He added, "Both calcium and parathyroid hormone are known to promote the growth of ...

Low Vitamin D Tied to Depression in Older Adults

... Poor levels also cause increase in serum parathyroid hormone readings, study says FRIDAY, ... D and high levels of a hormone secreted by the parathyroid glands may increase the risk of depression in ... poor vitamin D status causes an increase in serum parathyroid hormone levels. Symptoms of depression often ...

Vitamin D Use Linked to Lower Mortality in Kidney Patients

... often take calcitriol to treat elevated levels of parathyroid hormone (hyperparathyroidism), a condition that ... clinical knowledge is limited to its effect on parathyroid hormone levels," study co-author Dr. Bryan ... appeared to be unrelated to its effect on parathyroid hormone levels. The study is published in the ...

The Second National Audit Report of the BAETS

... thyroid surgery was only 79%. The analysis for parathyroid surgery includes data from 1,896 procedures ... than ten cases each year. Like thyroid surgery, parathyroid surgery is consultant-led with evidence of ... collection. Overall, there were good outcomes for parathyroid disease and the evidence clearly shows good ...

New protein discovery helps researchers understand autoimmune diseases

... the target for the immune systems attacks on the parathyroid glands in the disease APS-1. This finding enables ... University, who made the discovery. The parathyroid glands are the most recently described anatomical ... The fact that the protein NALP5 was found in the parathyroid glands enhances our understanding of their ...

JCI table of contents: Nov. 8, 2007

... NEPHROLOGY: A bone to pick with the parathyroid A careful balance of mineral levels in the ... have demonstrated a link between FGF23 and the parathyroid gland, an organ that is vital in calcium homeostasis. The parathyroid glands ...

PREOS(R) Granted U.S. Orphan Drug Status for Treatment of Hypoparathyroidism

... most often caused by injury to or removal of the parathyroid glands during neck surgery. It also occurs as an ... palliative therapies, the absence of endogenous parathyroid hormone compromises the body's ability ... . About PREOS PREOS is recombinant human parathyroid hormone (PTH). NPS has studied PREOS in a number ...

Quest Diagnostics to Pay U.S. $302 Million to Resolve Allegations That a Subsidiary Sold Misbranded Test Kits

... Cosmetic Act relating to NID's Nichols Advantage Chemiluminescence Intact parathyroid Hormone Immunoassay, a test that was used by laboratories throughout the country to measure parathyroid hormone (PTH) levels in patients. As part of the plea, NID will pay a ...

Dilon Technologies' Slant15(TM) and LEHR Collimators Enhance Imaging Capabilities

... Uses include: breast imaging; sentinel node imaging; thyroid imaging; and parathyroid imaging. LEHR collimator is a high-resolution collimator for general nuclear medicine applications. Uses include thyroid imaging, parathyroid imaging, sentinel node imaging, spot bone imaging, gall bladder ejection, ...

Many Osteoporosis Medications Prevent Fractures, But None Is Proven Best

... calcitonin (a man-made hormone), calcium, vitamin D, testosterone, parathyroid hormone and selective estrogen receptor modulators (SERMs). Not enough ... that alendronate, risedronate and zoledronic acid, as well as estrogen and parathyroid hormone, prevent hip and other non-spinal fractures. Direct ...

Amgen's Denosumab and Eli Lilly's Forteo/Forsteo Will Drive Robust Annual Growth in the Osteoporosis Drug Market From 2013 to 2018

... of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that Amgen's novel agent denosumab and Eli Lilly's parathyroid hormone (PTH) analogue Forteo/Forsteo (teriparatide) will drive robust 4.3 percent annual growth in the osteoporosis drug market from 2013 to 2018 in ...

Businessman Exposed Problems With Quest Subsidiary's Blood Test Kits; Led to $302 Million Settlement

... patients at risk. As a result of the faulty tests, the lawsuit said, some dialysis patients underwent unnecessary surgery to remove their parathyroid and were administered unnecessary treatment that can cause a painful, deadly disease. Today's settlement covers claims that the bad tests led to ...

AACE/AIUM develop physician certification and accreditation in thyroid/parathyroid ultrasound

... (AIUM) have been working together to improve the quality of diagnostic ultrasound and ultrasound-guided invasive procedures of the thyroid and parathyroid glands. The quality of care depends in part on the knowledge and experience of the physician who performs and/or interprets the examination. With ...

Arab-American women need supplement to boost dangerously low vitamin D levels

... of fortified milk or fortified orange juice and vitamin supplements. Blood samples also were taken onsite and analyzed for levels of vitamin D and parathyroid hormone and other minerals. Dr. Hobbs says Henry Ford is launching an awareness campaign to educate the Arab American community in Dearborn about ...

Michigan Pre-Seed Capital Fund Invests in Three More Michigan Start-Ups

... test and a lung cancer prognostic test. -- Aursos, sponsored by the Kalamazoo SmartZone, received $200,000. Aursos specializes in parathyroid hormone (PTH) treatments for osteoporosis that increase bone formation and decrease bone degradation. To date, 25 additional seed-stage ...

High-normal phosphate levels linked to early atherosclerosis

... it cannot establish any cause-and-effect relationship. In addition, it lacked data on some possibly relevant laboratory valuesespecially parathyroid hormone and vitamin D, which, like phosphate, have important effects on bone. ...

Cytochroma Announces Positive Comparative Data on CTA018 in Chronic Kidney Disease Model

... therapy, limiting effectiveness. In a preclinical study of adenine-induced CKD, CTA018 was found to have consistent effectiveness in lowering parathyroid hormone (PTH) throughout a 4-week treatment period. In contrast, paricalcitol became progressively less effective. Additionally, CTA018 exhibited a ...

Heart Failure Raises Risk of Fractures

... the diuretic drugs often prescribed for people with heart failure might be bad for the bones, he said. Another possibility is the higher level of parathyroid hormone, which handles calcium and magnesium, often seen in heart failure could have a bone-weakening effect. Physicians treating people for heart ...

Bones mend faster without marrow

... a group of rats and drilled into the left thigh-bone of each animal before syringing out the bone marrow. Some of the rats received daily doses of parathyroid hormone (PTH), a clinically approved drug that encourages the growth of new bone. After two weeks, X-rays of the rats showed that new bone had begun ...

Too Little Vitamin D May Soften Baby's Skull

... statistically significant low levels of serum 25-OH vitamin D, the storage form of the vitamin. Some of these infants had symptoms of an overactive parathyroid gland, which is also consistent with vitamin D deficiency. The study appears in the Journal of Clinical Endocrinology & Metabolism . ...

NPS Pharmaceuticals to Report 2007 Financial Results

... two late-stage programs: GATTEX(TM) (teduglutide) is in Phase 3 clinical development for intestinal failure associated with short bowel syndrome and parathyroid hormone 1-84 [rDNA origin] injection is in Phase 2 clinical development as a hormone therapy for hypoparathyroidism. NPS has also completed a Phase 3 ...

E-mails Improve Patient-Surgeon Communication

... Dr. Peter Stalberg, of the Royal North Shore Hospital in Sydney, Australia, and his colleagues -- covers 100 patients who were undergoing thyroid or parathyroid surgery. All had access to their surgeon's e-mail address through their appointment card and a Web site, but half also received an information sheet ...

Procedure developed at Yale creates new bone

... Laboratories, Inc . It evaluated the effect of bone marrow removal from particular sites followed by daily injections of anabolic agents such as parathyroid hormone (PTH). The procedure creates new bone tissue that appears structurally and biologically normal and that endows the targeted bone with ...

Quest Diagnostics Reports Third Quarter Results

... of New York during the fourth quarter of 2004. The subpoenas requested a wide range of business records, including documents regarding parathyroid hormone ("PTH") test kits manufactured by NID and PTH testing performed by the Company. The Company has voluntarily and actively cooperated ...

Reunion with patient inspires follow-up study on treatment for DiGeorge syndrome

... DiGeorge syndrome is a common genetic immunodeficiency that occurs in one out of every 2,000 people. The syndrome includes thymic and parathyroid deficiency, chromosome abnormalities, low calcium levels and decreased immunity. Patients often have heart problems and developmental delay, which ...

Fluoride Damages the Thyroid, Report Shows

... an association between endemic goiter and fluoride exposure or enamel fluorosis in human populations -- fluoride adversely affects thyroid and parathyroid hormones, which affect bone health "If you have a thyroid problem, avoiding fluoride may be a good preventive health measure for you," writes ...

Use parathyroid hormone to fight brittle bone disease

... conducted on more than 1600 women reveals that parathyroid hormone (parathormone) increases the patient’s ... group that received 20 or 40 micro grams of parathyroid hormone every day. The women had to inject ... Previous research has suggested parathyroid hormone may stop and even reverse bone loss. One ...

Teriparatide for Brittle Bone Disorder

... OHSU School of Medicine, is examining the effectiveness of the synthesized parathyroid hormone, teriparatide, in increasing bone mass and improving bone structure in adults affected by OI. Teriparatide, derived from the human parathyroid gland, is manufactured and sold by Eli Lilly and Co. under the brand name ...

Larynx transplant restores patient's voice after 20 years

... the larynx's blood supply, they also transplanted the nearby thyroid and parathyroid glands, too. The patient now has two thyroid glands, both of which appear to work, as well as eight parathyroid glands. For three months following the surgery Heidler could not ...

Onions to prevent osteoporosis

... involved segregation of bone cells of newborn mice that were treated with parathyroid hormone to simulate a situation of osteoporosis. These cells were later ... Food Chemistry, issue May 2005. , Osteoporosis, onion, peptide, GPCS, parathyroid hormone, calcium, bone disease, loss of bone ...

Another osteoporosis buster: onion

... was performed on rats and their bone cells. The compound isolated from white onions called GPCS, glutamyl peptide did wonders and being treated with parathyroid hormone the bone cells improved resoprtion. So this study can greatly help women and their problem. onion is a new entrant for osteoporosis ...

Prostate Cancer Preventable By Vitamin D Analogs

... many disorders. Trials are under way to test its chemotherapeutic effect on established cancer. QW and particalcitol (Zemplar) have shown to reduce parathyroid hormone levels, which regulate the metabolism of calcium and phosphorus. The study of the transgenic adenocarcinoma of mouse prostate (TRAMP) ...

Geriatric Patients With Chronic Kidney Disease May Not Be Treated Properly

... tests for various types of cancer. Just half of the CKD patients underwent recommended tests for anemia, while only 15 percent had testing of parathyroid hormone levels. Patients with CKD were actually less likely than non-CKD patients to receive vaccinations for influenza and pneumococcal infection. ...

The Benefits of Strontium in the treatment for Osteoporosis Questioned

... treatment with an anabolic agent that enhances bone formation is preferable, and this is now possible since the introduction of recombinant parathyroid hormone (PTH). However, the use of PTH is limited by its high cost and the need for subcutaneous self-injection. Recently strontium ranelate has ...

Hope for Patients With Kidney Failure

... were genetically engineered to express higher-than-normal levels of the natural molecule hepatic growth factor (HGF) or another natural factor called parathyroid hormone-related protein (PTHrP). Both groups of mice developed normal kidney functions, thus allowing the researchers to study how the high levels of ...

New Hope for Kidney Failure

... were genetically engineered to express higher-than-normal levels of the natural molecule hepatic growth factor (HGF) or another natural factor called parathyroid hormone-related protein (PTHrP). Both groups of mice developed normal kidney functions, thus allowing the researchers to study how the high levels of ...