Eliminating Cell Receptor Prevents Infections in Animal Study
... to lack a particular receptor in heart and pancreas
cells, the study team prevented infection by a ... breed of mice. By manipulating genes in the pancreas
and heart that generate CAR in those organs, ... Subsequently, those mice had virus levels in the pancreas
a thousand times smaller than in control animals, ...
Cell Discovery May Bring Science Closer to Diabetes Cure
... role in directing cells to become part of the pancreas
or part of the biliary system, and researchers ... occurs when insulin-producing beta cells in the pancreas
are attacked by the immune system.
"With this ... "This might be used one day to replace a diseased pancreas
or bile duct in people."
The study appears in ...
Automated 'Artificial Pancreas' Controls Blood Glucose Levels in Diabetes Patients for First Time
... for the first time that an automated artificial pancreas
system (APS) can safely and effectively maintain ... linked and controlled through UCSB's artificial pancreas
software. The software's insulin delivery ... a number of other teams working on the artificial pancreas
project, but no other team has advanced yet to ...
Popular diabetes treatment could trigger pancreatitis, pancreatic cancer
... 2 diabetes may have unintended effects on the pancreas
that could lead to a form of low-grade ... pill form as Januvia, caused abnormalities in the pancreas
that are recognized as risk factors for ... is that the unwanted effects of this drug on the pancreas
would likely not be detected in humans unless ...
Researchers Successfully Create Computer-Simulated Model for Evaluating Artificial Pancreas
... Replicate Insulin-Producing Function of Healthy pancreas
for Type 1 Diabetes Patients -
SANTA ... the successful development of an artificial pancreas
for patients with diabetes has been achieved, ... for evaluating an investigational artificial pancreas
comprised of the OmniPod(R) Insulin Management ...
Surgical technique in Spain enables extirpation of benign tumors of the pancreas
... mainly neuroendocrine or cystic tumours of the pancreas
that are benign or of low malignant potential. ... in such a way that we are able to preserve the pancreas
to the maximum. This is why laparoscopic central ... to extirpate the minimum portion possible of the pancreas
and, consequently, avoid the risk of the patient ...
Cell transplantation and diabetes: New sites, new devices
... supportive, microenvironment for islets - is the pancreas
itself," said Van der Windt and co-authors.
Engineering a bioartificial pancreas
Another review by Dr. Cherie Stabler and ... and blood flow around the bioartificial pancreas
when compared to control implants," noted ....
JCI online early table of contents: June 5, 2008
INFLAMMATION: Why alcohol is bad for your pancreas
Much is known about the mechanisms by which ... known as carbachol develop an inflammation of the pancreas
(pancreatitis) that resembles the pancreatitis ... alcohol and carbachol exposure cause cells in the pancreas
to release vesicles containing degradative ...
New vaccine approach prevents/reverses diabetes in lab study at Children's Hospital of Pittsburgh
... injected the microspheres under the skin near the pancreas
of mice with autoimmune diabetes. The ... T cells from the immune system travel to the pancreas
and destroy beta cells, which produce insulin. ... which they used dendritic cells delivered to the pancreas
in another method to turn off the immune systems ...
Suspected cause of type 1 diabetes caught 'red-handed' for the first time
... from isolated insulin-making structures in the pancreas
known as the islets of Langerhans. They caught ... pancreas, we can look at why they get into the pancreas
and determine which of the materials that they ... they were challenging to isolate from the pancreas
for closer examination.
"They're very tiny ...
Jefferson scientists' discovery may help explain smoking-pancreatic cancer link
... levels are significantly higher in the blood and pancreas
tissue of pancreatic cancer patients. The ... and measured the amount of osteopontin in the rat pancreas
and blood. They found that the more cigarette ... in pancreatic cancer cells, Dr. Arafat explains. pancreas
tissue samples from pancreatic cancer patients ...
Pancreatic cancer: The smaller the tumor, the better your chances, study shows
... The odds of surviving cancer of the pancreas
increase dramatically for patients whose tumors ...
The findings in the current edition of pancreas
( www.pancreasjournal.com ) vividly underscore ... the need of finding and diagnosing tumors in the pancreas
as early as possible, Agarwal added. In order to ...
Elusive pancreatic progenitor cells found in mice
... the existence of a beta cell progenitor in the pancreas
after birth, but the identification and ... of beta cell mass in the injured part of the pancreas
within two weeks. The animals pancreases also ... and newly formed beta cells from human pancreas
in order to expand and differentiate them in ...
Stem Cells Finally Found in Pancreas
... has finally managed to locate stem cells in the pancreas
-- in mice, at least.
If the findings are ... scientists had all but abandoned hopes that the pancreas
made its own stem cells because they had failed ... with a capacity to divide exist in the pancreas
of man, and if we can identify the factors that ...
Protein power: Researchers trigger insulin production in diabetic mice
... the genes controlling the development of the pancreas
cells that make and release insulin to maintain ... shown that inserting the Pdx1 gene into liver or pancreas
cells can induce insulin production, but most ... and identified it as an important regulator of pancreas
development, said using viruses as vectors for ...
Pancreas May Be Key to Pregnancy-Linked Diabetes
... News) -- New information about a protein in the pancreas
may help in efforts to determine how diabetes ... known to have a role in preventing cancer in the pancreas
and other organs. Menin prevents pancreatic ...
However, insulin-producing islet cells in the pancreas
need to grow during pregnancy in order to produce ...
Cell Conversion Shows Promise for Diabetes Treatment
... a transcription factor that plays a key role in the conversion of pancreas
cells into insulin-producing beta cells, and the finding could lead to a ...
The study, published in the Aug. 7 issue of Cell , also shows that the pancreas
is capable of beta cell regeneration.
While this approach was effective ...
New role discovered for molecule important in development of the pancreas
... leads to diabetes; loss of two copies leads to a complete failure of the pancreas
to form. This new research expands the role of Pdx1 in beta-cell biology ... when both copies of the Pdx1 gene were truncated at the C terminus, the pancreas
formed, but the mice quickly developed diabetes. When they investigated ...
150 Children, Celebrities With Type 1 Diabetes Converge on Capitol Hill for JDRF's Children's Congress 2009
... Allen and Dr. Aaron Kowalski, JDRF's Research Director for the Artificial pancreas
Project. ESPN broadcaster Brian Kenny will moderate the forum.
The ... $174 billion in annual health care costs in the U.S. alone - a person's pancreas
stops producing insulin, the hormone that enables people to get energy ...
New Treatment Option at The Sarah Cannon Cancer Center Provides Hope for Inoperable Tumors
... to treat tumors anywhere in the body, even the brain, spine, lung, liver, pancreas
and prostate, with such accuracy that there is little or no damage to ... to treat: stomach (67%), liver (59%), myeloma (57%), prostate (55%), pancreas
(55%), bladder (54%), lung (52%), and colorectum (52%).
The Sarah ...
New Tests Spot Tough-to-Detect Cancers Sooner
... have developed new tests that make it easier to diagnose cancers of the pancreas
and bile ducts.
In a study, the new tests more than doubled the ... .
Doctors typically look for tumors in the bile duct and pancreas
region by snaking an endoscope down a patient's throat and into those ...
Amylin Pharmaceuticals to Present Compelling Efficacy and Safety Data From Diabetes Programs at ADA 2009
... who use insulin, and in patients with type 1 diabetes, those cells in the pancreas
are either damaged or destroyed, resulting in reduced secretion of both ... through multiple effects that work in concert on the stomach, liver, pancreas
and brain. BYETTA is approved by the FDA for use by people with type 2 ...
JDRF Illinois Names Allscripts CEO Glen Tullman 'Best of Illinois' for His Efforts to Find a Cure for Type 1 Diabetes
... raised more than $1 million, including over $500,000 for the Artificial pancreas
Program. The development of an artificial pancreas, one of JDRF's top ... that, through JDRF's cutting-edge research, which includes the Artificial pancreas
and other important breakthroughs, and the generosity of tens of thousands ...
Old diabetes drug teaches experts new tricks
... to maintain normal levels of cell energy production. After people eat, the pancreas
releases insulin, the hormone responsible for glucose absorption. Once ... signaling protein involved in the communication between the liver and the pancreas
that's necessary for maintaining glucose production by the liver and its ...
Type of connection procedure after pancreatic surgery influenced rate of pancreatic fistula
... After surgery to remove the head of the pancreas, invagination of the pancreas
into the small intestine resulted in a lower rate of pancreatic fistula, ... fistula has been associated with several factors, including soft pancreas
texture and surgical technique. It can result in prolonged hospitalization ...
Fox Chase performs the worlds first successful ViKY robot-assisted surgery for pancreatic tumors
... When patients present with pancreatic cancer localized to the tail of the pancreas
(instead of the head), they undergo a distal pancreatectomy, in which the surgeon removes the tail of the pancreas
and leaves the head attached. The remaining portion can function normally ...
'Personalized' genome sequencing reveals coding error in gene for inherited pancreatic cancer
... diseases," says Alison Klein, Ph.D., director of the National Familial pancreas
Cancer Tumor Registry at Johns Hopkins. "By finding the genetic error ... their finding has not yet resulted in a clinical test for the hereditary pancreas
cancer gene, but laboratories at Johns Hopkins and possibly elsewhere will ...
Compounds that trigger beta cell replication identified by JDRF funded researchers
... adolescents, and adults, in which the immune system attacks cells in the pancreas
that produce insulin, a hormone that enables people to convert food into ... spurring the body to copy existing functioning beta cells and coaxing the pancreas
to create new ones.
"Targeting beta cell regeneration is still a ...
Pennsylvanians May Donate Part of Tax Refund to Support Juvenile Diabetes Research
... results when the immune system destroys the insulin-producing cells of the pancreas
that regulates blood glucose. The pancreas
no longer produces insulin, the hormone needed to convert sugar (glucose), ...
New Diabetes Resource Provides Tools and Support to Families of Newly-Diagnosed Children with Type 1 Diabetes
... the immune system destroys the insulin-producing beta cells of the pancreas
that regulate blood glucose. Since the pancreas
can no longer produce insulin, people with type 1 diabetes require daily ...
Antioxidants offer pain relief in patients with chronic pancreatitis
... in Gastroenterology . CP is a progressive inflammatory disease of the pancreas
in which patients experience abdominal pain (in early stage) and diabetes ... for pain relief for such patients.
Pancreatitis is inflammation of the pancreas
that usually begins as a sudden attack and is often caused by gallstones, ...
Arterial infusion using gabexate mesilate: Is it effective therapy for severe acute pancreatitis?
... remains a lethal disease. It is defined as an inflammatory process of the pancreas
with possible peripancreatic tissue and multi-organ involvement inducing ... used to treat acute necrotizing pancreatitis cannot easily reach the pancreas
when administered intravenously, and, because of ischemia or impaired ...
Molecular marker identifies normal stem cells as intestinal tumor source
... in identifying the source of cancer stem cells in the lung, kidney, brain, pancreas
and other tissues.
"The idea that cancers might arise from mutant stem ... to be a useful marker to trace cancer stem cells in the kidney, brain, pancreas
and other tissues. The researchers are also exploring the use of stem cell ...
UIC in NIH-funded islet transplantation study for type 1 diabetes
... says Dr. Jos Oberholzer, principal investigator and director of cell and pancreas
transplantation at UIC.
"This research will help us find the most ... he said.
Islet transplantation involves isolating islets from a donor pancreas
and infusing the cells into the main blood vessel in the patient's liver. ...
Inspired by Diabetes U.S. National Contest Winners Share Stories of Perseverance and Success in Managing Diabetes
... art entry, a
pin-the-tale-on-the-donkey-style game, asks children to pin a pancreas
cartoon drawing of a pig. (The pancreas
is the body's organ that produces
insulin to regulate blood sugar levels; ...
Micromet, Inc. Reports First Quarter 2008 Financial Results
... expressed on colon, lung, breast, prostate, ovarian, gastric and pancreas
cancers and on cancer stem cells of colon, breast, prostate and pancreas
cancers. Cancer stem cells are believed to cause metastases and ...
Coming soon: Cell therapies for diabetes, cancer?
... for a host of diseases, including diabetes and cancer.
for diabetes sufferers
The construction of a safe and functional bioartifical pancreas
(BAP), complete with cells that can secrete insulin in response to blood ...
Antegrade bowel intussusception can cause recurrent, chronic postoperative intestinal obstruction
... pain and vomiting of 24-hour duration. Her history was significant for pancreas
divisum and chronic pancreatitis. Four years prior, she underwent a ... abnormalities. The indications to perform a Whipple procedure to correct pancreas
divisum are questioned by the authors in their paper. She required ...
Repligen Reports Second Quarter Fiscal Year 2008 Financial Results
... Corporate Update
Secretin for Imaging of the pancreas
In September, we had a meeting with the FDA to discuss the ... clinical study of RG1068, synthetic human secretin,
for MRI imaging of the pancreas
as well as the FDA's requirements for
registration. Based on our ...
Is RTA a new potential option for the treatment of hydatid cysts?
... University of Pittsburgh Medical Center (UPMC). In this Italian center, located in the heart of the Mediterranean Basin, liver, kidney, heart, lung, pancreas
and combined transplants, from both cadaveric and living donors, are performed. General cardiac surgery, abdominal surgery and interventional ...