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Pancreas in Medical News

Eliminating Cell Receptor Prevents Infections in Animal Study

... to lack a particular receptor in heart and pancreas cells, the study team prevented infection by a ... breed of mice. By manipulating genes in the pancreas and heart that generate CAR in those organs, ... Subsequently, those mice had virus levels in the pancreas a thousand times smaller than in control animals, ...

Cell Discovery May Bring Science Closer to Diabetes Cure

... role in directing cells to become part of the pancreas or part of the biliary system, and researchers ... occurs when insulin-producing beta cells in the pancreas are attacked by the immune system. "With this ... "This might be used one day to replace a diseased pancreas or bile duct in people." The study appears in ...

Automated 'Artificial Pancreas' Controls Blood Glucose Levels in Diabetes Patients for First Time

... for the first time that an automated artificial pancreas system (APS) can safely and effectively maintain ... linked and controlled through UCSB's artificial pancreas software. The software's insulin delivery ... a number of other teams working on the artificial pancreas project, but no other team has advanced yet to ...

Popular diabetes treatment could trigger pancreatitis, pancreatic cancer

... 2 diabetes may have unintended effects on the pancreas that could lead to a form of low-grade ... pill form as Januvia, caused abnormalities in the pancreas that are recognized as risk factors for ... is that the unwanted effects of this drug on the pancreas would likely not be detected in humans unless ...

Researchers Successfully Create Computer-Simulated Model for Evaluating Artificial Pancreas

... Replicate Insulin-Producing Function of Healthy pancreas for Type 1 Diabetes Patients - SANTA ... the successful development of an artificial pancreas for patients with diabetes has been achieved, ... for evaluating an investigational artificial pancreas comprised of the OmniPod(R) Insulin Management ...

Surgical technique in Spain enables extirpation of benign tumors of the pancreas

... mainly neuroendocrine or cystic tumours of the pancreas that are benign or of low malignant potential. ... in such a way that we are able to preserve the pancreas to the maximum. This is why laparoscopic central ... to extirpate the minimum portion possible of the pancreas and, consequently, avoid the risk of the patient ...

Cell transplantation and diabetes: New sites, new devices

... supportive, microenvironment for islets - is the pancreas itself," said Van der Windt and co-authors. ... , Engineering a bioartificial pancreas Another review by Dr. Cherie Stabler and ... and blood flow around the bioartificial pancreas when compared to control implants," noted ....

JCI online early table of contents: June 5, 2008

... INFLAMMATION: Why alcohol is bad for your pancreas Much is known about the mechanisms by which ... known as carbachol develop an inflammation of the pancreas (pancreatitis) that resembles the pancreatitis ... alcohol and carbachol exposure cause cells in the pancreas to release vesicles containing degradative ...

New vaccine approach prevents/reverses diabetes in lab study at Children's Hospital of Pittsburgh

... injected the microspheres under the skin near the pancreas of mice with autoimmune diabetes. The ... T cells from the immune system travel to the pancreas and destroy beta cells, which produce insulin. ... which they used dendritic cells delivered to the pancreas in another method to turn off the immune systems ...

Suspected cause of type 1 diabetes caught 'red-handed' for the first time

... from isolated insulin-making structures in the pancreas known as the islets of Langerhans. They caught ... pancreas, we can look at why they get into the pancreas and determine which of the materials that they ... they were challenging to isolate from the pancreas for closer examination. "They're very tiny ...

Jefferson scientists' discovery may help explain smoking-pancreatic cancer link

... levels are significantly higher in the blood and pancreas tissue of pancreatic cancer patients. The ... and measured the amount of osteopontin in the rat pancreas and blood. They found that the more cigarette ... in pancreatic cancer cells, Dr. Arafat explains. pancreas tissue samples from pancreatic cancer patients ...

Pancreatic cancer: The smaller the tumor, the better your chances, study shows

... The odds of surviving cancer of the pancreas increase dramatically for patients whose tumors ... The findings in the current edition of pancreas ( www.pancreasjournal.com ) vividly underscore ... the need of finding and diagnosing tumors in the pancreas as early as possible, Agarwal added. In order to ...

Elusive pancreatic progenitor cells found in mice

... the existence of a beta cell progenitor in the pancreas after birth, but the identification and ... of beta cell mass in the injured part of the pancreas within two weeks. The animals pancreases also ... and newly formed beta cells from human pancreas in order to expand and differentiate them in ...

Stem Cells Finally Found in Pancreas

... has finally managed to locate stem cells in the pancreas -- in mice, at least. If the findings are ... scientists had all but abandoned hopes that the pancreas made its own stem cells because they had failed ... with a capacity to divide exist in the pancreas of man, and if we can identify the factors that ...

Protein power: Researchers trigger insulin production in diabetic mice

... the genes controlling the development of the pancreas cells that make and release insulin to maintain ... shown that inserting the Pdx1 gene into liver or pancreas cells can induce insulin production, but most ... and identified it as an important regulator of pancreas development, said using viruses as vectors for ...

Pancreas May Be Key to Pregnancy-Linked Diabetes

... News) -- New information about a protein in the pancreas may help in efforts to determine how diabetes ... known to have a role in preventing cancer in the pancreas and other organs. Menin prevents pancreatic ... However, insulin-producing islet cells in the pancreas need to grow during pregnancy in order to produce ...

Cell Conversion Shows Promise for Diabetes Treatment

... a transcription factor that plays a key role in the conversion of pancreas cells into insulin-producing beta cells, and the finding could lead to a ... The study, published in the Aug. 7 issue of Cell , also shows that the pancreas is capable of beta cell regeneration. While this approach was effective ...

New role discovered for molecule important in development of the pancreas

... leads to diabetes; loss of two copies leads to a complete failure of the pancreas to form. This new research expands the role of Pdx1 in beta-cell biology ... when both copies of the Pdx1 gene were truncated at the C terminus, the pancreas formed, but the mice quickly developed diabetes. When they investigated ...

150 Children, Celebrities With Type 1 Diabetes Converge on Capitol Hill for JDRF's Children's Congress 2009

... Allen and Dr. Aaron Kowalski, JDRF's Research Director for the Artificial pancreas Project. ESPN broadcaster Brian Kenny will moderate the forum. The ... $174 billion in annual health care costs in the U.S. alone - a person's pancreas stops producing insulin, the hormone that enables people to get energy ...

New Treatment Option at The Sarah Cannon Cancer Center Provides Hope for Inoperable Tumors

... to treat tumors anywhere in the body, even the brain, spine, lung, liver, pancreas and prostate, with such accuracy that there is little or no damage to ... to treat: stomach (67%), liver (59%), myeloma (57%), prostate (55%), pancreas (55%), bladder (54%), lung (52%), and colorectum (52%). The Sarah ...

New Tests Spot Tough-to-Detect Cancers Sooner

... have developed new tests that make it easier to diagnose cancers of the pancreas and bile ducts. In a study, the new tests more than doubled the ... . Doctors typically look for tumors in the bile duct and pancreas region by snaking an endoscope down a patient's throat and into those ...

Amylin Pharmaceuticals to Present Compelling Efficacy and Safety Data From Diabetes Programs at ADA 2009

... who use insulin, and in patients with type 1 diabetes, those cells in the pancreas are either damaged or destroyed, resulting in reduced secretion of both ... through multiple effects that work in concert on the stomach, liver, pancreas and brain. BYETTA is approved by the FDA for use by people with type 2 ...

JDRF Illinois Names Allscripts CEO Glen Tullman 'Best of Illinois' for His Efforts to Find a Cure for Type 1 Diabetes

... raised more than $1 million, including over $500,000 for the Artificial pancreas Program. The development of an artificial pancreas, one of JDRF's top ... that, through JDRF's cutting-edge research, which includes the Artificial pancreas and other important breakthroughs, and the generosity of tens of thousands ...

Old diabetes drug teaches experts new tricks

... to maintain normal levels of cell energy production. After people eat, the pancreas releases insulin, the hormone responsible for glucose absorption. Once ... signaling protein involved in the communication between the liver and the pancreas that's necessary for maintaining glucose production by the liver and its ...

Type of connection procedure after pancreatic surgery influenced rate of pancreatic fistula

... After surgery to remove the head of the pancreas, invagination of the pancreas into the small intestine resulted in a lower rate of pancreatic fistula, ... fistula has been associated with several factors, including soft pancreas texture and surgical technique. It can result in prolonged hospitalization ...

Fox Chase performs the world’s first successful ViKY robot-assisted surgery for pancreatic tumors

... When patients present with pancreatic cancer localized to the tail of the pancreas (instead of the head), they undergo a distal pancreatectomy, in which the surgeon removes the tail of the pancreas and leaves the head attached. The remaining portion can function normally ...

'Personalized' genome sequencing reveals coding error in gene for inherited pancreatic cancer

... diseases," says Alison Klein, Ph.D., director of the National Familial pancreas Cancer Tumor Registry at Johns Hopkins. "By finding the genetic error ... their finding has not yet resulted in a clinical test for the hereditary pancreas cancer gene, but laboratories at Johns Hopkins and possibly elsewhere will ...

Compounds that trigger beta cell replication identified by JDRF funded researchers

... adolescents, and adults, in which the immune system attacks cells in the pancreas that produce insulin, a hormone that enables people to convert food into ... spurring the body to copy existing functioning beta cells and coaxing the pancreas to create new ones. "Targeting beta cell regeneration is still a ...

Pennsylvanians May Donate Part of Tax Refund to Support Juvenile Diabetes Research

... results when the immune system destroys the insulin-producing cells of the pancreas that regulates blood glucose. The pancreas no longer produces insulin, the hormone needed to convert sugar (glucose), ...

New Diabetes Resource Provides Tools and Support to Families of Newly-Diagnosed Children with Type 1 Diabetes

... the immune system destroys the insulin-producing beta cells of the pancreas that regulate blood glucose. Since the pancreas can no longer produce insulin, people with type 1 diabetes require daily ...

Antioxidants offer pain relief in patients with chronic pancreatitis

... in Gastroenterology . CP is a progressive inflammatory disease of the pancreas in which patients experience abdominal pain (in early stage) and diabetes ... for pain relief for such patients. Pancreatitis is inflammation of the pancreas that usually begins as a sudden attack and is often caused by gallstones, ...

Arterial infusion using gabexate mesilate: Is it effective therapy for severe acute pancreatitis?

... remains a lethal disease. It is defined as an inflammatory process of the pancreas with possible peripancreatic tissue and multi-organ involvement inducing ... used to treat acute necrotizing pancreatitis cannot easily reach the pancreas when administered intravenously, and, because of ischemia or impaired ...

Molecular marker identifies normal stem cells as intestinal tumor source

... in identifying the source of cancer stem cells in the lung, kidney, brain, pancreas and other tissues. "The idea that cancers might arise from mutant stem ... to be a useful marker to trace cancer stem cells in the kidney, brain, pancreas and other tissues. The researchers are also exploring the use of stem cell ...

UIC in NIH-funded islet transplantation study for type 1 diabetes

... says Dr. Jos Oberholzer, principal investigator and director of cell and pancreas transplantation at UIC. "This research will help us find the most ... he said. Islet transplantation involves isolating islets from a donor pancreas and infusing the cells into the main blood vessel in the patient's liver. ...

Inspired by Diabetes U.S. National Contest Winners Share Stories of Perseverance and Success in Managing Diabetes

... art entry, a pin-the-tale-on-the-donkey-style game, asks children to pin a pancreas on a cartoon drawing of a pig. (The pancreas is the body's organ that produces insulin to regulate blood sugar levels; ...

Micromet, Inc. Reports First Quarter 2008 Financial Results

... expressed on colon, lung, breast, prostate, ovarian, gastric and pancreas cancers and on cancer stem cells of colon, breast, prostate and pancreas cancers. Cancer stem cells are believed to cause metastases and ...

Coming soon: Cell therapies for diabetes, cancer?

... for a host of diseases, including diabetes and cancer. Artificial pancreas for diabetes sufferers The construction of a safe and functional bioartifical pancreas (BAP), complete with cells that can secrete insulin in response to blood ...

Antegrade bowel intussusception can cause recurrent, chronic postoperative intestinal obstruction

... pain and vomiting of 24-hour duration. Her history was significant for pancreas divisum and chronic pancreatitis. Four years prior, she underwent a ... abnormalities. The indications to perform a Whipple procedure to correct pancreas divisum are questioned by the authors in their paper. She required ...

Repligen Reports Second Quarter Fiscal Year 2008 Financial Results

... Corporate Update Secretin for Imaging of the pancreas In September, we had a meeting with the FDA to discuss the ... clinical study of RG1068, synthetic human secretin, for MRI imaging of the pancreas as well as the FDA's requirements for registration. Based on our ...

Is RTA a new potential option for the treatment of hydatid cysts?

... University of Pittsburgh Medical Center (UPMC). In this Italian center, located in the heart of the Mediterranean Basin, liver, kidney, heart, lung, pancreas and combined transplants, from both cadaveric and living donors, are performed. General cardiac surgery, abdominal surgery and interventional ...
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(Date:9/18/2014)... A new GSA Bulletin study uses ... Rio Puerco and Chaco Wash in northern New Mexico, ... salt cedar and willow, investigators were able to precisely ... They then combined this data with aerial imagery, LiDAR, ... of these arroyos. , Arroyos are deep, oversized channels ...
(Date:9/18/2014)... novel robotic system that can operate inside the bore ... part of a biomedical research partnership program at Brigham ... determining if the robot, in conjunction with real-time MRI ... less costly, and less discomforting for the patient. The ... cancer therapies with greater precision. , Developed by a ...
(Date:9/18/2014)... The fall foliage season that prompts millions of Americans to ... later and possibly last a little longer within a century, ... leaf peeping in some areas of the United States as ... report in the journal Global Ecology and Biogeography . ... that is the state tree of New Hampshire could ...
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(Date:9/22/2014)... Metformin, a drug commonly used to treat diabetes, may ... (TSH) among patients with an underactive thyroid, a new ... levels may be associated with heart problems and broken ... this study. Among those in the study with ... low levels of thyroid-stimulating hormone per year compared with ...
(Date:9/22/2014)... Medical experts this past weekend gathered ... discuss brain-related diseases facing an aging population, including ... disorders. , Each of the 50 attendees ... memory care community or hospice office. Silverado, with ... hosts the annual event to facilitate the exchange ...
(Date:9/22/2014)... anxiety, excessive perspiration these symptoms are a few ... the body,s heart rate and plays a crucial role ... from Tel Aviv University points to an additional complication ... published in Mammalian Genome , was conducted by ... the Department of Human Molecular Genetics and Biochemistry at ...
(Date:9/22/2014)... leadership of Senators Sherrod Brown (D-Ohio) and Patty ... care services were lauded yesterday by the American ... representing internal medicine and related subspecialties. A ... introducing the Ensuring Access to Primary Care for ... extend current-law payment rates under Medicaid for certain ...
(Date:9/22/2014)... is one of 11 collaborating institutions that have been ... National Science Foundation for a project focused ... include plant symbionts, animal and human pathogens and decomposers ... used in numerous industrial processes and fermentation of foods, ... Symbiotic associations with zygomycetes may have facilitated the origin ...
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