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Offspring in Medical News

Unlocking the key to human fertility

... match, however similar their DNA is, no viable offspring can be born. Occasionally, for example, with horses and donkeys, offspring are produced - but because the sperm and egg ... their development as embryos is abnormal and any offspring are almost always infertile. The research ...

Postpartum Anxiety May Delay Puberty in Kids

... anxiety after giving birth and that their female offspring had delayed onset of puberty. Prolactin, which ... groups, mothers with low prolactin raising female offspring of mice with normal prolactin levels, and mothers with normal prolactin levels raising the female offspring of mice with low levels of prolactin. Puberty ...

Outgoing Nature Could Get You to 100

... Perls and his colleagues decided to look at 246 offspring of those who lived to 100 to see if their ... norms for each trait. They found that the offspring of centenarians were more extraverted than the ... sources of help when needed, Perls said. The offspring of centenarians scored lower than the norms on ...

Researchers identify personality traits

... Society . Previous research on siblings and offspring of centenarians have documented that exceptional ... runs strongly in families. Studies of the offspring of centenarians showed that their mortality is ... be important to the healthy aging observed in the offspring of centenarians. Using the NEO-Five-Factor ...

What Moms Learned May Be Passed to Offspring

... exercise. These mice later gave birth to offspring with the same genetic mutation. But the offspring showed no signs of memory problems even though ... effect reached into the next generation. The offspring had improved memory even without an enriched ...

Smoking during pregnancy fosters aggression in children

... light up during pregnancy can predispose their offspring to an additional risk: violent behaviour. ... Another risk factor for aggressive behaviour in offspring was smoking mothers with a history of antisocial ... 18 months to three and a half years. Aggressive offspring were characterized by their mothers as quick to ...

New Study Data: JANUVIA™ (sitagliptin) Significantly Reduced Blood Sugar Levels and Was Not Associated with Hypoglycemia in Elderly Patients with Type 2 Diabetes

... increased the incidence of rib malformations in offspring at 1000mg/kg, or approximately 100 times human ... day 21 decreased body weight in male and female offspring at 1000mg/kg. No functional or behavioral toxicity was observed in offspring of rats. Placental transfer of sitagliptin ...

Children of Older Fathers at Risk for Bipolar Disorder

... offspring of men 55 and older were 1.37 times more likely ... and family history of psychotic disorders, the offspring of men 55 years and older were 1.37 times more ... be diagnosed as having bipolar disorder than the offspring of men aged 20 to 24 years," wrote Emma M. Frans, ...

Children of older fathers more likely to have bipolar disorder

... and family history of psychotic disorders, the offspring of men 55 years and older were 1.37 times more ... be diagnosed as having bipolar disorder than the offspring of men aged 20 to 24 years," the authors write. The offspring of older mothers also had an increased risk, but ...

Mom's Unhealthy Diet May Have Long-Term Impact on Baby

... of regular feed. The researchers compared the offspring of the two groups of female rats and found those ... Both increase the risk of heart disease. The offspring of the junk food-fed mothers also had higher ... through adolescence and into adulthood than the offspring of the mothers who ate a healthier diet during ...

AAAS symposium to address significant effects of the male parent in reproductive success

... affect fetal and postnatal development of offspring and that this imprint can be expressed in ... produce a wide spectrum of deficits in offspring and be expressed in subsequent generations, said ... reproductive outcome. The reported impact on offspring outcome includes low birth weight; increase in ...

Understanding the have-knots: The role of stress in just about everything

... world of rat nurturance is licking and grooming. offspring of rat mothers who naturally lick and groom their ... in other words, less sensitivity to stress than offspring of less nurturant mothers. The same thing is true of offspring of naturally less nurturant mothers who are ...

Parents show bias in sibling rivalry, says study

... unit in that there are two parents, a number of offspring and interactions between parents and their young, ... mediate competition between different aged offspring compared to what happens when the young were left ... that the parents attach more value to the older offspring as their maturity gives them a better chance of ...

Household chemical may affect breast development

... with butyl benzyl phthalate (BBP), which their offspring then absorbed via breast milk. The offspring ingested levels of chemical estimated to be ... effect on certain characteristics of the female offspring of the rats, such as the ratio of uterine weight ...

JCI table of contents: Nov. 21, 2007

... substantially decrease the fertility of female offspring to the long list of possible negative outcomes. ... have normal sized litters. However, their female offspring had markedly reduced numbers of resting and early ... of PAHs on the number of follicles in female offspring were mediated through the aryl hydrocarbon ...

Smoking Before, After Pregnancy Harms Daughters' Fertility

... offspring had fewer egg follicles, mouse study shows ... the number of eggs in the ovaries of their female offspring by two-thirds. This limits the window in which ... of PAHs on the number of follicles in female offspring were mediated through a receptor that affects the ...

Adult offspring of parents with PTSD have lower cortisol levels

... of the stress hormone cortisol than the adult offspring of parents without PTSD, according to a report in ... completed by the offspring. Twenty-three of the offspring had parents with PTSD, and 10 had parents without ... related to having a mother with PTSD. offspring with parental PTSD also demonstrated changes in ...

Eating junk food whilst pregnant and breastfeeding may lead to obese offspring

... during pregnancy and lactation gave birth to offspring which overate and had a preference for junk foods rich in fat, sugar and salt when compared to the offspring of rats given regular feed. The research team ... lead author Dr Stphanie Bayol. "This could send offspring on the road to obesity and make the task of ...

Cell division find prompts overhaul of immune response modeling

... for the first time in science, followed hundreds of lymphocytes and their offspring through all their cell divisions until their deaths. They also recorded ... of the National Academy of Sciences USA. "We found that all the offspring of a single cell died at the same cell division; their lifespan is ...

Researchers estimate risk of transmission of Huntington's disease to offspring among male carriers

... The researchers estimated the conditional probability of an offspring inheriting an expanded allele from a father with a high normal allele by ... estimated probability that a male high normal allele carrier will have an offspring who develops HD ranges from 1/6,241 to 1/951," said lead author Audrey ...

Trauma experienced by a mother even before pregnancy will influence her offspring's behavior

... third, control group, were not given any form of stress. When the rats' offspring reached maturity (at 60 days), the researchers examined their emotional ... doubt different from that of the rats from the control group. All the offspring of stressed mothers showed reduced social contact compared with that of ...

ADA releases position paper on obesity, reproduction and pregnancy outcomes

... to obese mothers have "a higher prevalence of congenital anomalies than do offspring of normal-weight women, suggesting that maternal (obesity) alters ... among children of obese women. "Other birth defects more frequent in offspring of obese women include oral clefts, heart anomalies, hydrocephaly and ...

Parental Insomnia Can Harm Adolescent Children

... Arand said, adding that only a few research studies have focused on offspring of people with insomnia. Yet insomnia, which refers to a number of ... in life, but this is, to my knowledge, the first time we've looked at offspring and realized we have a significant problem," Arand said. A second ...

Different mutations in single gene suggest Parkinson's is primarily an inherited genetic disorder

... roughly trace when and where mutations occur, and how they travel through offspring and in populations, says Kristoffer Haugarvoll, M.D., a visiting scientist ... are occurring in a few founders, and that these founders have a lot of offspring over generations that carry the mutation. Even in sporadic disease, then, ...

Why your fertility cells must have 'radio silence'

... commonly known as the fruit fly. If the mother fly lacks PGC, her offspring will be unable to produce germ cells. Initially, Dr. Lasko said, they ... fruit flies without the ability to produce the protein produce sterile offspring which produce no sperm or eggs. "What the study argues is that this ...

Iowa State University researcher's work on gender, temperature link in reptiles published in Nature

... by the chromosomes an embryo inherits from the father -- Y dictates the offspring will be male, X means female. The mother always contributes an X chromosome. In some species of reptiles, the gender of the offspring is determined by the temperature the embryos experience during ....

Foods From Cloned Animals Safe to Eat: FDA

... decision almost four years ago that food from cloned animals and their offspring was safe. The agency said additional studies confirmed its initial ... one cow. Agency officials said it would probably take several years for offspring of clones to enter the marketplace. Even then, it's not clear how many ...

January American Naturalist highlights

... that females mate frequently, even when bouts of mating decrease offspring production. This finding is counterintuitive because we would expect ... aging process. But, the daughters of frequent mating mothers had enhanced offspring production. Are the benefits to daughters enough to recoup the costs of ...

Common Household Chemical Could Raise Breast Cancer Risk

... added. For the study, Russo's team fed lactating rats BBP, which their offspring absorbed through breast milk. The rat pups received levels of the chemical ... . The researchers found that BBP affected characteristics of the female offspring of the rats, such as more rapid breast development and changes in the ...

Penn Veterinary Medicine report new strategy to create genetically modified animals

... mated these recipient males with wild-type females, 10 percent of offspring carried the gene originally introduced into the transplanted germ cells, ... These inefficient and difficult methods also carry a risk of producing offspring with developmental abnormalities. The use of retroviral or lentiviral ...

Many Parents Share Genetic Test Findings With Kids

... the BRCA mutation are discussing their genetic test results with their offspring often many years before the offspring would need to do anything," said study author Dr. Angela Bradbury, ...

Females avoid incest by causing male relatives to leave home

... them access to many females and enabling them to sire a higher number of offspring in the long term. Most males end up dispersing because a higher number of ... Through this research we could genetically determine paternity for most offspring produced in a 10-year monitoring period. ...

Prioritize Pregnant Women to Get Swine Flu Shot, Experts Say

... published recently in the New England Journal of Medicine found just such a transfer of protection among a group of Bangladeshi women and their offspring who received the seasonal flu vaccine. Dr. Marc Siegel, an associate professor of medicine at New York University Langone Medical Center in New ...

Agent Orange Linked to Parkinson's, Heart Disease

... with many other cancers, including esophageal, stomach, colorectal and pancreatic; with miscarriages, stillbirths or low birth weight in the offspring of exposed veterans or with neurodegenerative diseases other than Parkinson's. However, the committee found "limited or suggestive evidence of no ...

Study provides documentation that tumor 'stem-like cells' exist in benign tumors

... no hormones. Both types of stem-like cells were found to be self-renewable and multipotent, meaning they expressed proteins that could enable their offspring to differentiate into several types of cells. Studies also showed that both hormone-producing and non-producing tumor stem cells can be ...

Tiny levels of carbon monoxide damage fetal brain

... disease. We know that it exacerbates disease." "We believe that the minute levels of carbon monoxide in the mother rats' environment made their offspring more vulnerable to illness," added Edmond. "Our findings highlight the need for policy makers to re-examine the regulation of carbon monoxide." ...

Pre-Diabetes Costs Nation $25 Billion Annually in Extra Medical Care, New Data Show

... Among infants, gestational diabetes results in an increased risk of death, jaundice, hypoglycemia and respiratory distress syndrome. Further, adult offspring of mothers with gestational diabetes have a significantly increased risk of developing type 2 diabetes as well as cardiovascular disease. "The ...

Slightly Underactive Thyroid May Be a Plus

... population suggest the opposite. Higher TSH could actually benefit you." Surks and his colleagues also found that the centenarians and their offspring were more likely to have a particular variant of a TSH receptor. Those with that variant -- nearly 60 percent of the centenarians -- tended to have ...

Morning Sickness Drug Gets Green Light in Study

... trimester of their pregnancies. The study found no significantly increased health risks for babies of women exposed to the drug compared with the offspring of women who hadn't taken it. The risk of birth defects, for instance, was 5.3 percent in the metoclopramide group and 4.9 percent in the group not ...

Studies Report More Harmful Effects From BPA

... transplant patients to try to replicate the findings. In another study, researchers report on the mechanism by which BPA affects fertility in the offspring of rodents. "The genes that are necessary for normal pregnancy are altered," explained study author Dr. Hugh Taylor, director of the division of ...
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