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Bionovo Presents Positive Results from Phase 1B Trial of Bezielle for Metastatic Breast Cancer

... Oncology at Ohio State University. The primary objective of the study was to identify the maximum ... 180 days. Three patients (19%) on Bezielle had objective tumor regression, as evaluated by an independent ... and of these four patients, one patient had objective tumor regression during 449 days of Bezielle ...

Advanced targeted therapies effective as first-line treatment for lung cancer

... The study assessed the clinical outcomes of objective response rate and progression-free survival among ... had longer progression-free survival and greater objective response rate compared to chemotherapy in ... in overall survival, a significant improvement in objective response rate was observed. Vandetanib treatment ...

Peregrine Pharmaceuticals Reports Financial Results for Fiscal Year 2009

... patients in the initial cohort demonstrated an objective tumor response according to RECIST criteria. ... patients in the initial cohort achieved an objective tumor response according to RECIST criteria. ... patients in the initial cohort, achieved an objective tumor response according to RECIST criteria. ...

ASCO Research Foundation Grant Will Support Study of Peregrine's Bavituximab in Lung Cancer

... evaluable NSCLC patients, or 64.7%, achieved an objective tumor response according to response evaluation ... but not limited to, the risk that the rate of objective tumor response for the expansion stage of the Phase II trial will not be consistent with the objective tumor responses experienced in the first stage of ...

DFG establishes nine new collaborative research centers

... The new Collaborative Research Centres: The objective of SFB 840, "From Particulate Nanosystems to ... congenital and adoptive immune reactions. The objective is to research how viruses succeed in avoiding ... prerequisite for significant developments. The objective is to employ geoscientific and archaeological ...

BioVex To Announce Updated Survival Data From a Phase II Clinical Study of OncoVEX GM-CSF in Metastatic Melanoma at The 2009 American Society of Clinical Oncology Meeting

... The trial was designed to measure overall objective response, which is defined as a complete response ... conventional and experimental prior therapies. 13 objective systemic responses (26% objective response rate) were achieved including nine CRs, ...

Florida Cardiologist First in United States to Acquire Innovative Shape-HF Cardiopulmonary Testing System

... his patients. "Until now we have not had an objective way to measure a heart patient's response to ... Shape-HF overcomes these limitations. It provides objective data to the cardiologist right in the office or ... measures patient response to therapy, offers objective criteria for patient functional classification, ...

Treating sleep disorders in people with traumatic brain injury may not eliminate symptoms

... Results indicate that treatment may result in the objective resolution of the sleep disorder without ... hypersomnia. Participants underwent objective evaluation by overnight polysomnography to detect the presence of sleep disorders, and both objective and subjective tests were used to measure daytime ...

Peregrine Pharmaceuticals' Bavituximab Achieves Primary Endpoint in First Stage of Phase II Breast Cancer Study

... Shows Seven of 14 Evaluable Patients Achieved objective Tumor Response by the End of Two Treatment ... tumor response, with seven patients achieving an objective response by approximately eight weeks, after ... criteria for the number of patients achieving an objective tumor response in each of the three clinical ...

RAND Launches Unique Tool to Evaluate Health Care Proposals

... will help make realistic assessments, based on objective standards and facts, and therefore encourage a ... RAND. "We created COMPARE to contribute credible, objective and easy-to-understand facts and analysis so that ... is a nonprofit research organization providing objective analysis and effective solutions that address the ...

New training method helps surgeons evaluate their own minimally invasive surgery skills

... As a result there is now, for the first time, an objective benchmark for measuring a surgeon's basic skills ... unstructured manner and, moreover, without any objective benchmark with which to measure the progress made ... required by surgeons, thus paving the way for objective benchmarking of their competence in the field of ...

Wyeth Announces Positive Data from Phase 2 Study of Neratinib in Advanced HER-2-Positive Breast Cancer

... rate. Secondary end points included safety, objective response rate (complete and partial responses) ... as evaluated by independent assessment. The objective response rate was 26 percent, and the clinical ... PFS was 40 weeks by independent assessment. The objective response rate was 56 percent, and the clinical ...

Research highlights new approaches to prevent blood clots

... (370 patients) for six months. The primary objective of the study was to determine whether ... idraparinux (i.e., bioequipotency). The secondary objective of the study was occurrence of clinically ... end of six months of therapy. A final objective included the reversal of the anticoagulant effect ...

Acumen Fund Announces New Investments In Pakistan To Build Scalable Business That Serve The Poor

... a global microinsurance sector. Its overall objective is to establish the ability of commercially ... step towards reaching Kashf Foundation's core objective of providing inclusive "financial services ... institution for the poor and serve its broader objective of deepening Kashf's services to the overall ...

New System Devised To Guide Doctors Treating Patients With Symptomatic Myocardial Bridging

... were in class A - Having clinical symptoms but no objective signs of ischemia. 62 were in class B - Having clinical symptoms and objective signs of ischemia by non-invasive stress tests. ... 37 were in class C - Having clinical symptoms and objective altered intracoronary hemodynamics, based on ...

New system devised to guide doctors treating patients with symptomatic myocardial bridging

... were in class A Having clinical symptoms but no objective signs of ischemia. 62 were in class B Having clinical symptoms and objective signs of ischemia by non-invasive stress tests. 37 were in class C Having clinical symptoms and objective altered intracoronary hemodynamics, based on ...

Hot flashes underreported and linked to forgetfulness

... subjective, or self-reported, hot flashes and objective performance on memory tests in women. These ... during a hot flash. Both subjective and objective hot flashes were recorded during a 24-hour period. The average number of objective hot flashes was 19.5 per day. Maki and ...

Vion Pharmaceuticals Announces Presentation of Data from Phase III Trial of Cloretazine(R) (VNP40101M) and Cytarabine in Relapsed Acute Myelogenous Leukemia at the ASCO(R) Annual Meeting

... measures could be pursued in the future. The objective response rate of the cytarabine and ... mortality between the two arms, in light of the objective response rate of the cytarabine and ... The primary endpoint for the trial was the objective response rate, defined as CR plus CRp (a ...

TAK-390MR Phase 3 data presented at Digestive Disease Week

... enrolled in the two global studies. The primary objective was to evaluate overall healing rates over eight ... in the global, six-month study. The primary objective was to evaluate the overall maintenance rate of ... TAK-390MR 30 mg, 60 mg, or placebo. A secondary objective was to evaluate the frequency of heartburn over ...

Hasbro Children's Hospital presents at 2008 Pediatric Academic Societies Meeting

... (PEDs) based on insurance status. The objective of this study was to assess the difference in ... has yet to be studied in pediatrics. The objective of this study was to determine the effect of soft ... and hypertension in children. The objective of this study was to determine if ...

Aflac Incorporated Announces First Quarter Results, Declares Second Quarter Cash Dividend

... quarter sales growth would be below our annual objective due primarily to an expected slow start in ... channel should help Aflac Japan achieve its sales objective of a 3% to 7% increase in yen for 2008. "Our ... be more challenging to achieve our 2008 sales objective of an 8% to 12% increase, but we still believe it ...

3M Health Care announces new 3M Rapid Detection Flu A+B test

... designed to deliver reliable, qualitative and objective electronic results in 15 minutes. Expected to ... the Rapid Detection Flu Test quickly delivers objective results through an easy-to-use self-timed reader. ... Medical Division. This tests ability to provide objective results and its ability to read and store data ...

Scientific poster abstracts from the 24th annual meeting of the American Academy of Pain Medicine

... with acute (APPS) or chronic (CPPS) pain. The objective of this study was then to develop some ... deconditioning that results from inactivity. objective assessment of physical conditioning in patients ... Studies 212 A Possible Solution to objective Muscle Pain Assessment: The Muscle Pain Detection ...

Aflac Incorporated Announces Fourth Quarter Results

... the year. That result was in line with our 2007 objective of a 15% to 16% increase in operating earnings ... for the year were consistent with our 2007 sales objective of a 6% to 10% increase. Sales in the ... proud that we achieved our primary financial objective of a 15% to 16% increase in operating earnings ...

Top-Line Data Available from Three Ipilimumab Pivotal Trials in Patients with Advanced Metastatic Melanoma

... primary endpoint, which was to rule out a best objective response rate of less than 10 percent. However, ... response effect observed in study 022 and best objective response rates across the three studies ranging ... determined by independent radiology review. The objective responses were consistent with previous ...

ZOLINZA (vorinostat) in combination with bortezomib demonstrated clinical activity

... and/or refractory multiple myeloma. The primary objective of both trials was to determine the maximum ... disease or intolerable toxicity. The primary objective was to determine MTD; secondary objectives ... 20 mg was added on days 4-8. The primary objective was to determine the MTD and pharmacokinetic and ...

Pharmasset Presents R7128 14-Day Monotherapy Study Results for the Treatment of Chronic Hepatitis C

... previously failed interferon therapy. The primary objective was to assess the safety, tolerability ... (BID) dosing for 14 days. The secondary objective was to assess antiviral activity by measuring the ... hepatitis C virus (HCV) genotype 1. The primary objective is to assess the safety, tolerability and ...

Breaking Studies - Masimo's Technologies the Focus of Multiple Clinical Studies at Last Week's American Society of Anesthesiologists' Annual Meeting

... oximetry, reported that multiple independent and objective clinical studies and a case study were presented ... studies add to the more than 100 independent and objective studies demonstrating the superiority of Masimo ... More than 100 independent and objective studies have confirmed that Masimo SET technology ...

New tool to assess excessive daytime sleepiness in adolescents published in JCSM

... evidence of a sleep related breathing disorder by objective overnight polysomnographic monitoring or reported ... and controls. The CASQ was associated with objective measures derived from the polysomnograms, or a ... the association between the CASQ and additional objective measures of sleepiness and sleep duration, as ...

Provectus Pharmaceuticals, Inc. releases summary results of phase 1 metastatic melanoma study

... SD and 25% achieved PD, corresponding to an objective response (CR+PR) in 40% of subjects and local ... of subjects. Among those subjects achieving an objective response of their treated tumors, 25% achieved an objective response of their untreated bystander tumors, and ...

Quigley Corporation Announces Final Results of Quigley Pharma's Phase IIb Study

... Endpoints: Efficacy: The primary efficacy objective is to demonstrate that treatment with QR-333 improves pain relief, as demonstrated through the VAS pain scale. The secondary efficacy objective is to demonstrate that treatment with QR-333 improves symptomatic diabetic ...

Full Transcript of House Democrats' Press Conference on Introduction of Health Care Legislation

... eluded so many Presidents and Congresses for far too long, and that is the objective of getting good quality, affordable health care insurance to every ... we have among the members, both Democrats and Republicans, with the objective that we are going to get a bill. We cannot allow this issue to be ...

105-Day Mars Simulation: U.S. Studies Focus on Improving Work Performance

... to counter sleep disruption due to shift work or long hours, tested two objective methods of measuring the impact of stress and fatigue on performance, and ... F. Dinges, lead investigator): The project tested two novel, unobtrusive, objective methods for monitoring impact of fatigue and stress on work performance. ...

105-day Mars simulation: US studies focus on improving work performance

... to counter sleep disruption due to shift work or long hours, tested two objective methods of measuring the impact of stress and fatigue on performance, and ... F. Dinges, lead investigator): The project tested two novel, unobtrusive, objective methods for monitoring impact of fatigue and stress on work performance. ...

Forest Laboratories Announces Positive Top-line Data from Two Pivotal Phase III Trials of Ceftaroline for the Treatment of Community-acquired Bacterial Pneumonia (CABP) Requiring Hospitalization

... Ceftaroline Met Primary objective and Achieved High Clinical Cure Rates in Adult Patients Hospitalized for ... trials (FOCUS I and II) demonstrate that ceftaroline met the primary objective of non-inferiority and achieved high clinical cure rates compared with ...

House Bill to Provide Cancer Patients With Solution for Quality Cancer Care Within an Equitable Medicare Model

... program that rewards quality cancer care while controlling costs. The objective of the QCCD is to combine two critical patient enhancing components: ... and reporting systems, and then involves the program implementation. The objective is to collect data to refine quality metrics and the reimbursement ...

Results From Phase 1 Clinical Study of PEG-PAL in PKU and Update on Phase 2 Clinical Study

... receiving a single dose, and a 6-week follow-up period. The primary objective of the study was to assess the safety and tolerability of single, ... period where doses can be increased up to 2.0 mg/kg/week. The primary objective is to evaluate the effect of PEG-PAL on blood Phe concentrations in ...

Pharmasset Initiates Phase 1b Multiple Ascending Dose Clinical Trial of PSI-7851 in Chronic Hepatitis C Patients

... first dose of PSI-7851 to be tested will be 50mg once daily. The primary objective is to assess the safety, tolerability and pharmacokinetics of PSI-7851 after repeat dosing over 3 days. The secondary objective is to evaluate the decrease in HCV RNA. Results from both studies ...

Heart Rhythm Society Introduced to New Method for Optimizing Cardiac Resynchronization Therapy During Exercise

... gas exchange parameters to assess these changes provides a completely objective method for defining response to CRT therapy." Only Device to ... time in bed or lying on the couch," said Dr. MacCarter. "Our objective is to get them off the couch, back on their feet and enjoying life ...

Olanzapine Long-Acting Injection (LAI) Efficacy and Safety Data Presented at American Psychiatric Association Annual Meeting

... LAI and oral olanzapine was presented. About HGKB The primary objective of this ongoing open-label study is to examine the long-term safety and ... (2.9 at baseline to 2.8 at endpoint). About HGLQ The primary objective of this two-year, ongoing open-label study is to compare the treatment ...
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(Date:8/22/2014)... August 21, 2014 Diabetes affects nearly 10 ... complaints of diabetics: constant finger pricking to test ... Chemical Biology reports the development of a protein ... accurate results for diabetes patients. In the American ... Daunert, Ph.D., shows off her "designer protein" that ...
(Date:8/22/2014)... discoveries in basic and clinical research and technological ... a complex offensive spanning multiple fronts. , Work ... could help find new and more selective therapies ... targets a specific enzyme overexpressed in certain cancersand ... brain tumours. , Chemistry professor Christopher Cairo and ...
(Date:8/22/2014)... antioxidants and can reduce free radical damage. ... oxidative stress? Jianbo Zhao and co-workers from ... University, China discovered that green tea polyphenol ... apoptosis, indicating green tea polyphenols play a ... oxidative stress. The relevant study has been ...
Breaking Biology News(10 mins):New enzyme targets for selective cancer therapies 2New enzyme targets for selective cancer therapies 3
(Date:8/23/2014)... 2014 "When men sit down to ... with the dirty water inside the bowl, the interior ... one of two inventors from Naugatuck, and Bridgeport, Conn. ... this protective device." , They developed the IPSAFE to ... the water, bowl and seat. This minimizes exposure to ...
(Date:8/23/2014)... Angeles, CA (PRWEB) August 23, 2014 ... options trading system created by Greg Marks has been ... launch earlier this month. The commotion surrounding the new ... prompting an investigative review. , “In recent ... options trading software systems, commonly referred to as robots ...
(Date:8/23/2014)... MPWMD Board of Directors voted on Monday, August 18th to ... water for commercial and industrial properties. This was accomplished ... LLC in Carmel, California. , This is a historical ... in the State of California has approved this technology for ... time can now be used as a sole source of ...
(Date:8/23/2014)... Young adults in Athens, GA who find that they have a ... and call the new helpline which can offer support and guidance ... Teen Athens is a wonderful resource for an adolescent drug or ... to end substance abuse once and for all. When a young ... peers when really they should put their faith in a youth ...
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