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Myeloma in Medical News

Keryx Biopharmaceuticals Announces Agreement with FDA on a Special Protocol Assessment for Phase 3 Trial of KRX-0401 (Perifosine) in the Treatment of Multiple Myeloma

... in relapsed or relapsed / refractory multiple myeloma patients previously treated with bortezomib ... of Bortezomib and Dexamethasone in Multiple myeloma Patients Previously Treated with Bortezomib" will ... "Perifosine holds great promise for multiple myeloma patients worldwide. We at Dana-Farber, along ...

Multiple Myeloma Genome Unlocked

... -- The sequencing of the first three multiple myeloma whole genomes has been completed by U.S. ... samples was conducted as part of the Multiple myeloma Genomics Initiative. Overall, more than 250 ... have been collected and additional multiple myeloma genomes are being sequenced, according to a news ...

CancerCare Launches New Program to Help Multiple Myeloma Patients Cover Transportation Costs

... grants of up to $600 annually to multiple myeloma patients for covering transportation costs such ... to people affected by cancer. Multiple myeloma is a cancer of the bone marrow that is diagnosed ... therapies and the disease itself, many multiple myeloma patients may be required to visit their doctors ...

New Report Just Published: World Multiple Myeloma Therapeutics Market Report

... report to its catalogue. World Multiple myeloma Therapeutics Market ... This report analyzes the US market for Multiple myeloma Therapeutics in Millions of US$. The market for multiple myeloma therapeutics is analyzed by the following Drugs: ...

Individuals Who Apply Pesticides Are Found to Have Double the Risk of Blood Disorder

... linked agricultural work to an increased multiple myeloma risk. Our study is the first to show an ... screening study that virtually all multiple myeloma patients experienced a MGUS state prior to ... malignancies (such as multiple myeloma or lymphoma) were excluded. Cancer incidence and ...

Cancer research partnership between UCSF, MMRF to drive drug development

... California, San Francisco (UCSF) and the Multiple myeloma Research Foundation (MMRF) have established the Stephen and Nancy Grand Multiple myeloma Translational Initiative, a research ... San Francisco. Mr. Grand, age 65, is a multiple myeloma patient at the UCSF Helen Diller Family ...

MMRF and the Broad Institute to perform whole genome sequencing of multiple myeloma samples

... The Multiple myeloma Research Foundation (MMRF) announced today a ... uncover the molecular changes underlying multiple myeloma by whole genome sequencing of individual patient ... Genomics Research Institute the Multiple myeloma Genomics Initiative a comprehensive genome ...

Data on VELCADE(R) (Bortezomib) for Injection Based Therapies to be Presented at the International Myeloma Workshop

... will be featured at the Fifth International myeloma Workshop (IMW) in Washington, D.C., February 26 - ... with relapsed or previously untreated multiple myeloma (MM). (Logo: ... outcomes." Previously Untreated Multiple myeloma Presentations at the IMW conference will ...

International Panel of Experts Gather for Roundtable Consensus Regarding Multiple Myeloma Related Disease

... Wednesday, February 25, 2009, the Institute for myeloma and Bone Cancer Research (IMBCR) will host a ... Hotel just prior to the 12th Annual International myeloma Workshop in Washington, D.C. MGUS is a ... an increased risk to develop cancers including myeloma and lymphoma with a very high risk of bone loss ...

Managing Myeloma (www.managingmyeloma.com) Launches - A Comprehensive Information and Educational Site for Physicians, Nurse Practitioners, Physician Assistants, and Pharmacists

... and education on the treatment of multiple myeloma by a multidisciplinary network of health care practitioners. The goal of Managing myeloma ( www.managingmyeloma.com ) is to provide an ... suffering from multiple myeloma. Multiple myeloma is the second most common hematologic malignancy, ...

Researchers Identify Novel Mechanism That Make Cancer Tumors Grow

... Scientists at the Institute for myeloma and Bone Cancer Research (IMBCR) have uncovered a ... of IMBCR's multi-year research project, "Cure myeloma Project," this research was funded by grants from ... Foundations, Kramer Family Foundation and the myeloma Research Fund. About IMBCR The ...

Institute of Myeloma and Bone Cancer Research in Los Angeles Proudly Announces That Ethan Horwitz, Esq of King & Spalding Law Firm has Joined its Board of Directors

... -- Established in 2004, the Institute for myeloma and Bone Cancer Research (IMBCR) is the only ... therapies and ultimately a cure for multiple myeloma and metastatic bone disease. Ethan Horwitz, ... cancers." About IMBCR: The Institute for myeloma and Bone Cancer Research is headquartered in Los ...

1.2 Million Dollars Recently Awarded to Institute for Myeloma and Bone Cancer Research

... of philanthropic donor-advised funds and the myeloma Research Foundation are the latest major donors to the "Cure myeloma Project", an ongoing research initiative at the Institute for myeloma and Bone Cancer Research, (IMBCR), in Los ...

Combo Therapy Helps Multiple Myeloma Patients

... to boost immune function can help some multiple myeloma patients, according to interim results from an ... or stabilized disease in 76 percent of multiple myeloma patients who'd relapsed after previous treatment. ... for use with dexamethasone for multiple myeloma patients who've had previous treatment. The ...

Drug combination improves or stabilizes disease for relapsed multiple myeloma patients

... immune functions improved or stabilized multiple myeloma for 76 percent of patients who had relapsed after ... thalidomide and lenalidomide. Multiple myeloma ( http://www.mayoclinic.org/multiple-myeloma/ ) ... approval for lenalidomide in previously treated myeloma patients. "We're getting good results with less ...

Keryx Biopharmaceuticals' KRX-0401 (Perifosine) Data Selected for Oral Presentation at the 50th Annual Meeting of the American Society of Hematology

... with Relapsed or Relapsed / Refractory Multiple myeloma Who Were Previously Relapsed from or ... bortezomib in relapsed and refractory multiple myeloma patients who were all previously treated with ... efficacy of KRX-0401 as a treatment for multiple myeloma and related disorders and continue to explore the ...

Combination Therapy Helps to Combat Myeloma

... 27 (HealthDay News) -- Patients with multiple myeloma who could not tolerate high dose chemotherapy ... assigned 682 patients with newly diagnosed myeloma to nine six-week cycles of treatment with ... new drug combination could be a real benefit for myeloma patients who aren't eligible for high-dose ...

Treatment with anti-anemia drugs may not be safe for multiple myeloma patients

... may have a negative impact on the survival of myeloma patients. In the study, 323 multiple myeloma patients were evaluated over a 20 year period in ... of whether ESAs are harmful in patients with myeloma is a pressing clinical issue with at least eight ...

Thalidomide Continues to Show Benefits Against Myeloma

... once-banned drug thalidomide for patients with myeloma have learned a lesson that's as true to life as ... and a professor of medicine and director of the myeloma Institute for Research and Therapy at the ... is both for patients but, importantly, for myeloma physicians and investigators, to exercise ...

One Gene May Be Key to Myeloma

... MONDAY, June 23 (HealthDay News) -- Cancerous myeloma cells are so "addicted" to a gene known as IRF4, ... of the gene by only 50 percent is enough to kill myeloma cells without compromising other healthy ... "This pathway is so critical to the growth of myeloma that, potentially, if you turn it off, you've ...

FDA Approves VELCADE(R) (Bortezomib) for Injection for Patients with Previously Untreated Multiple Myeloma

... for patients with previously untreated multiple myeloma (MM). The Company's co-development ... VELCADE treatment also is available for multiple myeloma patients in the second- and third-line settings, ... in 1163 patients with previously treated multiple myeloma (N=1008, not including the Phase III, VELCADE ...

Senesco Expands on Preclinical Multiple Myeloma Findings

... details of its continuing preclinical multiple myeloma research. In February 2008, the Company announced ... was able to induce apoptosis in multiple myeloma tumors when injected intratumorally. Senesco ... both preclinical animal models and human multiple myeloma cell lines, while also studying ...

McCarty Cancer Foundation Awards $50,000 Grant for Myeloma Research Program at Karmanos Cancer Institute

... a $50,000 grant for the multi-center Multiple myeloma Clinical Research Initiative coordinated by ... and novel therapies for patients with multiple myeloma and related conditions. (Logo: ... Dr. Zonder the $50,000 grant in support of the myeloma Research Program. McCarty stated, "We are ...

Publication of Clinical Results Underscores VELCADE(R) (Bortezomib) For Injection Based Therapy As a Standard of Care In Newly Diagnosed Multiple Myeloma Patients

... neuropathy. About Multiple Myeloma Multiple myeloma is the second most common hematological ... U.S., more than 55,000 individuals have multiple myeloma and approximately 20,000 new cases are diagnosed ... for the treatment of patients with multiple myeloma who have received at least one prior therapy. ...

Millennium and Harvard Medical School Sign Cooperative Agreement for Research in Novel Field of Cancer Biology

... for Injection, the market leader for multiple myeloma and mantle cell lymphoma patients, who have ... for the treatment of patients with multiple myeloma who have received at least one prior therapy. ... VELCADE is approved for patients with multiple myeloma after first relapse. Risks associated with ...

Stem cells make bone marrow cancer resistant to treatment

... have evidence that cancer stem cells for multiple myeloma share many properties with normal stem cells and ... overcome the cells drug resistance. Multiple myeloma affects bone marrow and bone tissue. Cancer ... cancers cells. Working with cell samples from myeloma patients, the team found that this stem cell ...

Kosan Opens TIME-1 Pivotal Phase 3 Trial in Multiple Myeloma

... as a potential treatment for multiple myeloma is open for enrollment. TIME-1 is a pivotal Phase ... who have failed numerous (at least three) prior myeloma therapies, will be closed and replaced with an ... and antitumor activity in patients with multiple myeloma as monotherapy and in combination with Velcade. ...

Millennium Submits sNDA for VELCADE(R) (Bortezomib) for Injection for the Treatment of Front-Line Multiple Myeloma

... of patients with previously untreated multiple myeloma (MM). The filing is based on data from the 682 ... and prednisone About Multiple Myeloma Multiple myeloma is the second most common hematologic malignancy ... for the treatment of patients with multiple myeloma who have received at least one prior therapy. ...

Cytopia Commences Phase II Cancer Drug Study

... or refractory multiple myeloma. Multiple myeloma is an incurable cancer of plasma cells of the ... the disease. While some significant advances in myeloma therapy have occurred in recent years, disease ... for the company." The market for multiple myeloma drugs was estimated at US$930 million in 2006 and ...

VELCADE(R) (Bortezomib) for Injection Based Therapy Produced Significant Complete Remission Rates Pre- and Post-Transplantation in IFM Phase III Front-Line Multiple Myeloma Trial

... each arm. About Multiple Myeloma Multiple myeloma is the second most common hematologic malignancy ... for the treatment of patients with multiple myeloma who have received at least one prior therapy. ... VELCADE is approved for patients with multiple myeloma after first relapse. Risks associated with ...

New therapeutic options for newly diagnosed multiple myeloma patients

... today presented results of a phase II trial of myeloma induction therapy -- a first step therapy ... annual meeting. For newly diagnosed multiple myeloma patients, this new treatment provides a more ... M protein (abnormal protein present in blood of myeloma patients) and a significantly higher rate of good ...

Phase III Trial of VELCADE(R) (Bortezomib) for Injection Showed Dramatic Fourfold Increase in Complete Remission Rates When Combined With the Most Commonly Used U.S. Regimen in Front-Line Multiple Myeloma

... for patients with previously untreated multiple myeloma (MM). The trial was conducted by the Italian ... is one of the three Phase III front-line multiple myeloma trials presented at ASH that clearly establishes ... in each arm. About Multiple Myeloma Multiple myeloma is the second most common hematologic malignancy ...

Thalidomide Added to Standard Therapy Prolongs Overall Survival in Newly Diagnosed Multiple Myeloma Patients Over Age 75

... 17.6 Month Overall Survival Advantage in Elderly myeloma Patients when Thalidomide Is Added to ... over age 75 newly diagnosed with multiple myeloma compared to standard treatment, consisting of ... for newly diagnosed patients with multiple myeloma up to 75 years of age, those older than 75 ...

Highest Reported Complete Remission Rate of 35 Percent Achieved in a Phase III Front-Line Multiple Myeloma Trial With Velcade(R) (Bortezomib) for Injection Based Therapy

... These patients with previously untreated multiple myeloma (MM) were ineligible for stem ... About Multiple Myeloma Multiple myeloma is the second most common hematologic malignancy ... for the treatment of patients with multiple myeloma who have received at least one prior therapy. ...

Keryx Biopharmaceuticals, Inc. Announces Poster Presentations Highlighting Observed Clinical Activity of KRX-0401 (Perifosine) to be Presented at the Upcoming American Society of Hematology Meeting in Atlanta, Georgia

... of Patients with Relapsed/Refractory Multiple myeloma to be presented on Saturday, December 8th at ... of patients with relapsed/refractory multiple myeloma are currently available and can be viewed on-line ... with Relapsed or Relapsed/Refractory Multiple myeloma (MM): Promising Activity as Combination Therapy ...

Pharmion to Present Clinical Data on Key Hematology Products at American Society of Hematology (ASH) Annual Meeting

... (MDS), acute myeloid leukemia (AML), multiple myeloma (MM), Hodgkin's lymphoma (HL), and two forms of ... in newly diagnosed elderly patients with multiple myeloma will be the subject of an oral presentation at ... Myeloma: Firstline Phase III Trials in Multiple myeloma -- Oral Presentation -- 4:30 p.m.: ...

Drug combination effective against multiple myeloma, researchers show

... the United States and Canada, 353 patients with myeloma received either a combination of lenalidomide ... professor in the Department of Lymphoma and myeloma at The University of Texas M. D. Anderson Cancer ... collaborative study by North American Multiple myeloma Study Investigators, and an international trial ...

Oral drug sets a new survival standard for bone marrow cancer

... Revlimid, an oral cancer drug, all measures of myeloma showed significant improvement in patients where ... placebo group. According to the International myeloma Foundation, follow-up data from the U.S. study ... States where most cancers are decreasing, and myeloma is being found in increasingly younger patients. ...

Drug Combo Boosts Multiple Myeloma Survival

... regulatory approval in June of 2006 for multiple myeloma patients who had already failed one treatment. ... from 20.2 to 29.6 months," she said. Multiple myeloma is a cancer of the blood's plasma cells that ... against various disorders including multiple myeloma and syndromes related to HIV infection. ...

Stress hormone may hasten the progression of certain blood cancers

... several types of cancers of the blood, multiple myeloma strikes nearly 20,000 Americans each year, ... Yang and Glaser focused on three multiple myeloma tumor cell lines, each representing a different ... The FLAM-76 cell line was prepared from multiple myeloma tumor cells taken from a patient whose disease ...
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