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Microarray in Medical News

GenVault's GenSolve(TM) Reagents Enable State-of-the-Art Genomic Analysis of Dried Blood Spots

... recover DNA from Guthrie cards and FTA paper for microarray based genomic analysis and Illumina iSelect based ... sufficiently high quality for use in genome-wide microarray analysis and SNP genotyping studies. Previously ... for analysis on systems such as the Illumina 610 microarray platform," said Dr. Mike Hogan, GenVault's Chief ...

Penn study demonstrates new way to boost immune memory

... the body encounters it a second time. Using microarray analysis and a program that searches protein ... Fatty acids can be broken down for energy and the microarray analyses revealed that TRAF6-deficient CD8 T ... regulate this process. Consistent with the microarray findings, CD8 T cells lacking TRAF6 display ...

Novel DNA microarray chip predicts functional impairment and remission in rheumatoid arthritis

... Paris, France, Friday 13 June 2008: A new DNA microarray chip can predict severe disability and remission ... of treatment for individual patients. The DNA microarray chip was developed as a tool to study 71 gene ... said: "Prognostic markers, identified through our microarray chip, can be used to predict disease outcomes in ...

Study identifies molecular response of cartilage to injury

... rheumatologists and biotechnologists conducted a microarray screening of adult human joint cartilage ... to that of uninjured control explants using microarray technology. The explants were obtained either ... into the pathways revealed in this injury microarray is likely to be highly informative, Dr. Vincent ...

Sanofi-Aventis renews licenses for Genomatix chip analysis pipeline

... licenses for Multi-Site access to the Genomatix microarray Analysis Pipeline. The pipeline provides a fully ... for the analysis of expression and tiling microarray experiments, including the powerful ChIP on chip ... analysis. Martin Seifert, Vice President microarray Business and Collaborative Research at Genomatix ...

Affymetrix Reports Second Quarter 2009 Results

... website at www.affymetrix.com. About Affymetrix GeneChip(R) microarray technology is the industry-standard tool for analyzing complex genetic ... and more than 18,000 peer-reviewed papers have been published using its microarray technology. Affymetrix is headquartered in Santa Clara, California. For ...

Exiqon Announces 2009 North American Grant Award Winners

... line for microRNA investigation, including products for RNA isolation, microarray analysis, qRT-PCR analysis, Northern Blotting, In Situ Hybridization, and Knockdown studies. Exiqon also offers microRNA profiling services for both microarray and qRT-PCR analysis, complete with full sample QC and customized data ...

Mapping gene expression with Gene Expression Atlas

... Atlas collates data from over 1000 different independent studies, mainly microarray experiments, with more than 30,000 samples in total. The new database is the latest product of the EBI's microarray Informatics group and has its origins in the EBI's ArrayExpress resource. ...

Prometheus Presents Proprietary Oncology Diagnostic Platform at ASCO Annual Meeting

... Tumor Cells (CTCs) in Metastatic Tumors Using Proximity Mediated microarray Immunoassay," Prometheus demonstrated that its novel microarray platform can successfully detect the activation of key cancer pathways ...

Exiqon Announces New Grant Program for MicroRNA Research

... line for microRNA investigation, including products for RNA isolation, microarray analysis, qRT-PCR analysis, Northern Blotting, In Situ Hybridization, and Knockdown studies. Exiqon also offers microRNA profiling services for both microarray and qRT-PCR analysis, complete with full sample QC and customized data ...

GeneGo and OmicSoft Announce Integration

... for the analysis of high dimensional quantification data (e.g. microarray or Taqman data), genotype data (e.g. SNP data, Copy Number data). The ... solution on the market. Array Studio includes support for all popular microarray platforms (Affymetrix, Agilent, Illumina, etc.), as well as support for ...

Five UCSF Scientists Elected to National Academy of Sciences

... quickly identifying, and measuring levels of, proteins in cells. Unlike microarray technology, which identifies and measures levels of messenger RNA -- a key ... into protein. The new technique, similar in speed, depth and accuracy to microarray technology, determines which proteins, and how many, are being produced, ...

Pathwork Diagnostics Launches Version of Its Tissue of Origin Test for FFPE Specimens

... To determine the tumor's origin, the Pathwork Tissue of Origin Test uses microarray technology to measure the expression pattern, comprising more than 1,500 ... FFPE and frozen tissue specimens. Upon specimen receipt, Pathwork runs the microarray test on the specimens, and a staff pathologist interprets the test results ...

Genetic blueprint revealed for kidney design and formation

... said. Helping make this discovery possible is the study's use of microarray technology to measure relative expression levels of every gene in each ... (laser capture micro-dissection and florescent activated cell sorting), microarray analysis allowed a more quantitative and sensitive measure of varied gene ...

Pathwork Tissue of Origin Test Shows Potential to Aid in the Diagnosis of Cancer of Unknown Primary

... specimens where by definition the primary site is unknown. The test uses a microarray to measure the expression pattern, comprising more than 1,500 genes, in ... handling and rigorous quality control procedures for RNA extraction and microarray analysis, tumor classification utilizing the Tissue of Origin Test will ...

Theranostics Health Signs Research Collaboration Agreement

... Laser Capture Microdissection (LCM) and Reverse Phase Protein microarray (RPMA). The proprietary combination of these technologies provides a ... of Laser Capture Microdissection (LCM) and Reverse Phase Protein microarray (RPMA) both developed by the company's co-founders Drs. Lance Liotta and ...

Measuring medicine: How new technologies could help doctors predict patient outcomes

... gave rise to high numbers of circulating tumor cells, a technique called microarray analysis was used to build a genetic profile of their tumors. Microarrays ... of circulating tumor cells. With this knowledge it was possible to use microarray analysis to predict whether a tumor was likely to disseminate large ...

St. Jude gene study reveals basis of anticancer drug resistance in childhood leukemia

... measured the response to initial methotrexate treatment and then used gene microarray analysis to measure the activity levels of 12,357 genes in the patients. In microarray analysis, researchers apply genetic material from the patients leukemia ...

Forsyth launches 1-of-a-kind core service to enable rapid identification of bacterial samples

... service for the research community. The Forsyth Microbial Identification microarray Service (MIM) enables the rapid identification of bacterial species in ... samples. The first service offering, Human Oral Microbe Identification microarray (HOMIM), will focus on detection of bacterial profiles from the oral ...

BioDiscovery Joins Illumina Connect Bioinformatics Program

... program offered by Illumina, Inc., for downstream analysis of microarray data. After collaborating with Illumina, BioDiscovery has successfully ... About BioDiscovery, Inc. BioDiscovery is a leader in the development of microarray advanced bioinformatics software and services that enable its customers ...

Virginia Commonwealth University to Study Genomics-Based Diagnostic Test:

... unique processes have enabled us to overcome the challenges of applying microarray technology for clinical use and develop clinically useful diagnostic tests ... data," explained Pathwork President and C.E.O. Deborah J. Neff. "The microarray is a great platform because we can look at so many pieces of information ...

Autism Consortium releases data on genes involved in autism to researchers worldwide

... Gene Discovery Project conducted the genome wide study using GeneChip microarray technology made by Affymetrix Inc, of Santa Clara, California, in their ... and perform whole-genome analyses in large populations. The Affymetrix microarray chips were processed by researchers in the Broad Institute's Genetic ...

Gene Chip Data Can Boost Cancer Outcomes

... fared better, doctor says FRIDAY, Sept. 21 (HealthDay News) -- DNA microarray chip analyses of tumors may help improve treatment for some patients with ... determine which drugs might offer them the most benefit, Lester used DNA microarray chips to analyze the patients' tumors for expression of certain genes ...

Microarray provides 3 genomic guides to breast cancer treatment decisions

... updates on the genomic predictors, which can be reported from a single microarray analysis of a needle biopsy of a patient's breast cancer. Symmans will ... "Let's say a new patient has a needle biopsy performed, and the microarray analysis of the tumor's gene expression predicts she is at low risk of ...

Studies Show Genetic Activity of Antioxidants

... Their reports were delivered at the American Heart Association's Basic Cardiovascular Sciences Conference 2009, held in Lake Las Vegas. "We used a microarray approach," said Dragan Milenkovic, a research scientist at the Centre de Clermont-Ferrand/Thiex in Saint Genes Champanelle, who described the ...

A new take on growth factor signaling in tamoxifen resistance

... its ability to identify subsets of disease and predict outcomes or drug responses, identifying new therapeutic approaches based on whole genome microarray profiling has, to date, been a significant challenge. By using GSEA, we've been able to use gene expression data to identify that activation of GF ...

'Ambry Genetics Announces Launch of Chromosomal Microarray to Offer Whole Genome Analysis'

... ALISO VIEJO, Calif., June 3 /PRNewswire/ -- Ambry Genetics is pleased to announce the launch of whole-genome Chromosomal microarray Analysis (CMA), offering the Ambry CMA: 105K Oligo Array, which is designed to identify chromosomal abnormalities associated with over 270 genetic ...

Ingenuity and Integromics Offer Integration for Comprehensive Genomics Analysis

... workflow-oriented solution for RT-qPCR data analysis, and IBD for TIBCO Spotfire(R) , an application to pre-process, normalize, and interpret raw microarray gene expression data, directly into IPA for better modeling, analysis, and understanding of their biological data. "Integromics' data analysis ...

UCSF creates fast, affordable tool for finding gene 'on-off' switches

... shRNAs that are able to potently deactivate a given gene has been extremely laborious and laden with many false results. The new method uses a microarray technology to generate large numbers of these shRNA strands for each target gene roughly 10 times the volume of traditional methods thereby ...

Baylor Research Institute Receives Multi-Million Dollar Grant To Develop Flu Vaccine

... at BRI has expanded into a new Center for Personalized Medicine led by Damien Chaussabel, Ph.D., a scientist at BIIR. This new center is using microarray technology to measure the expression of over 45,000 genes from a single tube of a patient's blood. What they have found is that the immune system ...

Novel gene predicts local recurrence in early onset breast cancer

... research discovered DEAR1 (ductal epithelium-associated ring chromosome 1) and implicated it in breast cancer, the team examined a tumor tissue microarray from 123 women whose breast cancer began between ages 25 and 49, all of whom advanced to invasive disease. Of these, 56 percent lacked DEAR1 ...

InDevR's FluChip detects and distinguishes swine-origin H1N1 from human influenza viruses

... human influenza viruses. "The FluChip assay detected all of the 6 swine-origin H1N1 viruses tested, and the resulting pattern, or signature, on the microarray was dramatically different than the signature for seasonal A/H1N1 and A/H3N2 viruses. Interestingly, the signature of the swine H1N1 virus indicated ...

Novel gene predicts local recurrence in early-onset breast cancer

... research discovered DEAR1 (ductal epithelium-associated ring chromosome 1) and implicated it in breast cancer, the team examined a tumor tissue microarray from 123 women whose breast cancer began between ages 25 and 49, all of whom advanced to invasive disease. Of these, 56 percent lacked DEAR1 ...

JNCI April 28 tip sheet

... the robustness and reproducibility of the test, the researchers evaluated the test on multiple tumor samples from each patient and used two different microarray platforms and two different biopsy techniques. The test was able to predict overall survival after adjusting for other clinical factors. The test ...

New strategy developed to diagnose melanoma

... diagnosis strategy is now being developed for clinical use by a diagnostics company. To develop the diagnostic tool, the researchers first used a microarray a "gene chip" -- to identify about 1,000 human genes that were present at different levels in malignant melanomas compared to benign moles. They ...

Pathwork Tissue of Origin Test Validation Study Published in Journal of Clinical Oncology

... data and the ability to both rule in and rule out tumor types." To determine the tumor's origin, the Pathwork Tissue of Origin Test uses microarray technology to measure the gene expression pattern, comprising more than 1,500 genes, in a tumor with an uncertain origin and compare it to expression ...

Penn vet researchers identify a critical growth factor that stimulates sperm stem cells to thrive

... which were relatively long-lived. Self-renewal and differentiation of SSCs provides the foundation for testis function and fertility. Using DNA microarray transcript profiling to identify specific genes whose expression are augmented in the SSC-enriched Thy1+ germ cell fraction of mouse pup testes, the ...

Best New Product Awards Winners Named at Molecular Medicine Tri-Conference

... data. Ovarian Cancer DSA Research Tool The Ovarian Cancer DSA(TM) research tool is the first high-density disease focused transcriptome based microarray for the study of ovarian. With ~100,000 transcripts derived from ovarian tissue, the Ovarian cancer DSA(TM) research tool represents the most ...

Genstruct and Gene Logic Collaborate on Systems Toxicology

... integrated genomics company providing comprehensive genomic reference databases, life science lab information management solutions, GLP-compliant microarray services and essential research consumables. Over 2/3rd of the top 25 pharma companies, leading research institutes and emerging biotech companies ...

Proteasome inhibition affects epigenetic mechanisms

... using the Tsukamoto-French model and were compared to rats given the proteasome inhibitor PS-341 (Bortezomib, Velcade) by intraperitoneal injection. microarray analysis and Real time PCR were performed and proteasome activity assays and Western blot analysis were performed using isolated nuclei. They ...
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(Date:11/5/2014)... career to understanding the Earth,s climate and communicating ... deputy director and regional climatologist for the Western ... Redmond has more than three decades of experience ... data to the general public. , At its ... December 15-19, 2014 the American Geophysical Union (AGU) ...
(Date:11/4/2014)... 2014) — Think about the way our bodies are ... cells know that they are supposed to become a ... tissues find the correct place and alignment? Researchers at ... questions. , In a new study, UM researchers describe ... their surrounding neighbors, at the head-trunk region. Their discovery ...
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