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Membrane in Medical News

Making nanoparticles in artificial cells

... sulphide particles in microscopically small membrane bubbles. Depending on which of the construction ... can be 4 or 50 nanometres in size. Because the membrane bubbles have the same size as living cells, the ... are similar to biological membranes. Like cells, membrane bubbles - or vesicles as scientists refer to them ...

Toray to establish water treatment R&D center at NTU in Singapore

... TWTL is part of Toray's vision to be a leading membrane manufacturer by 2010, particularly in the reverse osmosis membrane market for seawater desalination and reclamation ... Board (EDB), and NEWRI's R&D centres Singapore membrane Technology Centre (SMTC) and Institute of ...

RainEarth Applies for Patent for Second Generation Blood Dialysis Equipment

... and advantages. These include: a lower broken membrane rate, a higher gap rate, enhanced biological ... for adjusting dry spinning range in hollow fiber membrane that includes dry-wet spinning and ... control -- Synthetic hollow fiber membrane continuous spinning device -- Hollow ...

NxStage Announces Strategic Business Alliance with Asahi Kasei Kuraray Medical

... on similar terms. Hollow-Fiber membrane Supply Asahi will supply its high performance polysulfone hollow-fiber membrane to NxStage for NxStage branded products in North ... its core technology in functional materials for membrane filtration and selective adsorption with advanced ...

'Holy powder' ingredient makes membranes behave for better health

... resistance to infection and malignancy. "The membrane goes from being crazy and floppy to being more ... intermolecular interactions in the messy membrane environment has been a major challenge to ... work by interacting directly with membrane proteins, but the U-M findings challenge that ...

Why does aspirin increase the susceptibility of Helicobacter pylori to antimicrobials?

... of aspirin on the permeability of the outer membrane of H. pylori was determined using [7-3H] ... aspirin improved the permeability of the outer membrane of H. pylori . However, the expression of two ... probably by altering the expression of the outer membrane proteins (OMP) of H. pylori . Their study will ...

New findings measure precise impact of fat on cancer spread

... Those changes, including processes called membrane phase separation and membrane rounding, enhance cancer metastasis. "If the ... in polyunsaturated fats, caused increasing membrane phase separation, whereas oleic acid, found in ...

GEN Reports on Strategies to Overcome Blood-Brain Barrier

... of small molecules across the BBB by these membrane proteins is known as carrier-mediated transport ... may then be transported across the abluminal membrane of the endothelial cell (i.e., the membrane that interfaces with brain tissue) into the ....

Researchers gain new insight on wonder of cell division

... branching microfilaments along the inside surface membrane of a dividing cell. By down-regulating the ... of branched microfilaments at the right time, the membrane may be more malleable and better able to pinch ... act to modulate the stiffness of a cell's membrane to allow them to undergo shape changes needed for ...

New method to overcome multiple drug resistant diseases developed by Stanford researchers

... has overcome develops when pumps located in the membrane that encloses a cell become sensitized to a ... manages to avoid ejection by slipping through the membrane of the cell in between the pumps. The key is the ... properties by shaking hands with all these cell membrane components." That change in physical ...

Discovery first step to new therapies

... Centenary Institute have mapped the anatomy of a membrane protein. This exciting discovery has the ... development time for new treatments. "These membrane proteins are the target for 70% of all ... is to think of a lock and key. The lock is the membrane protein that causes the body to respond to ...

St. Jude Study Reveals a New Function for an Old Enzyme in Fatal Childhood Disease

... to dock and eventually fuse with the cell membrane and subsequently spill their active enzymes into ... for these organelles to fuse with the cell membrane and release their content outside the cell. When ... amount is reduced. Less LAMP-1 at the lysosomal membrane influences the capacity of lysosomes to dock at ...

Researchers identify proteins making up mechanosensitive ion channels

... channels are paths through the cell membrane that respond to mechanical forces such as ... method to measure the movement of ions across the membrane of Arabidopsis root cells as the pressure inside ... saw very little change in ion flow across the membrane as the pressure inside the cell increased. In ...

Novel toxin receptor discovered for ulcer-causing stomach pathogen

... he said. How the toxin crossed the membrane to get into these cells was a mystery, however. ... most can do so only after binding to a specific membrane component, called a receptor. Receptors sometimes ... is an important and abundant component of the membrane of some animal cells. (Foods such as milk, meat, ...

Unexpected role: EGFR protects cancer cells from starving

... factor receptor (EGFR) stabilizes another cell membrane protein that channels a constant supply of ... The team shows that EGFR binds to another cell membrane protein called the sodium/glucose co-transporter ... it continues to transport glucose from the cell membrane into the cell," Hung said. A "terrific ...

University of Pittsburgh researchers crack code of 3-D structure in key metabolic protein

... organisms, including humans. GlpD is a monotopic membrane protein, which means that although it is embedded ... membrane, the protein does not span the entire membrane to the interior of the cell. As a result, it is ... the highest resolution structure of a monotopic membrane protein that scientists have solved to date, and ...

Allergic response tied to lipid molecules in cell membrane

... the researchers first labeled the cell membrane and IgE antibodies with two different fluorescent ... previously showed that our fluorescently-labeled membrane probe has a longer lifetime within a ... results also show that lipid domains in the cell membrane associate with IgE antibodies and their receptors ...

St. Jude Researchers Find Key Step in Programmed Cell Death

... found that Hax1 and Parl pair up in the inner membrane of the mitochondria--tiny chemical packets that ... a protein called Bax into the mitochondrial outer membrane did not occur. This was significant since accumulation of Bax in the outer mitochondrial membrane allows the release of proteins that set off a ...

St. Jude researchers find key step in programmed cell death

... found that Hax1 and Parl pair up in the inner membrane of the mitochondriatiny chemical packets that ... a protein called Bax into the mitochondrial outer membrane did not occur. This was significant since accumulation of Bax in the outer mitochondrial membrane allows the release of proteins that set off a ...

Scientists identify proteins that help bacteria put up a fight

... agents and, more generally, how they adapt their membrane to new environmental conditions, such as those ... This action leads to modification of the membrane and the change in its charge. Ibba and Roy ... instead. This amino acid also contributes to cell membrane modification and seems to have additional ...

New findings contradict a prevailing belief about the inner ear

... inner ear, rather than rippling along the basilar membrane of the cochlea. The cochlea, located deep in the ear, is shaped like a snail. The basilar membrane essentially cuts the inner channel of the cochlea ... going into the ear undulate along the basilar membrane through the cochlea and eventually excite the ...

Uncovering the Achilles' heel of the HIV-1 envelope

... directed against a portion of HIV-1 called the membrane proximal ectodomain region (MPER). This region ... protein comprised of the gp120 protein plus the membrane anchoring gp41 subunits adjacent to the viral ... impede the ability of the virus to fuse to the membrane of the host cell. Importantly, the published ...

JCI online early table of contents: Jan. 10 2008

... cytoskeleton makes a firm attachment to the cell membrane Many features of a cell, including its ... of the cytoskeleton that is attached to the membrane of the cell. The molecule PIP2 has an important ... has a unique role in anchoring the cell membrane to the cytoskeleton of mouse megakaryocytes. ...

Researchers seek to make cavity-causing bacteria self-destruct

... chains, the main functional feature of S. mutans membrane fatty acids, grow longer. In fact, as many as 60 percent of the fatty acids in a bacterial outer membrane undergo this change as acidity increases, Quivey ... Without FabM, the mutant fills its outer membrane with other, smaller fatty acids that are much ...

New insights into deadly heart rhythm disorder

... dyes whose movement within the surface membrane of cells can be imaged in real time by special video cameras. Theyre also studying the membrane ion channels of the heart cells. These are the proteins in the cell membrane that come together to form special tiny openings ...

Ellex Announces New Retina Regeneration Therapy to be Presented at the AAO

... experiments to measure the ability of Bruch's membrane to transport water and chemicals have shown the ... diseases that are caused by a compromised Bruch's membrane resulting in reduced energy supply to, and waste ... dry form is associated with changes in Bruch's membrane that lead to atrophic cell death of the central ...

Revealing the workings of 'Mother Nature's blowtorch'

... requires separating the molecules from their membrane environment. Because part of cytochrome b5 sticks ... produce detailed images of proteins in the membrane environment, not only revealing molecular ... said. "In my opinion, solving the structures of membrane proteins should be the highest priority for ...

Story ideas from molecular & cellular proteomics

... 33 of the proteins on the envelope, which is the membrane surrounding the virus, and nine proteins in the ... that in very salty environments, the algas plasma membrane -- which is a barrier that protects it from the ... changes in the structure and composition of the membrane may help D. salina adapt to high salt content. ...

Live recordings of cell communication

... container loaded with neurotransmitter molecules. A vesicle fuses with the membrane surrounding a neuron, releases neurotransmitters into the surroundings ... - "We have lacked a method for measuring the fusion of vesicle and membrane on a nano-scale at the moment the process occurs. Until now it has only ...

Purdue researchers create prostate cancer 'homing device' for drug delivery

... year. The molecule Low's team created attaches to prostate-specific membrane antigen, or PSMA, a protein that is found on the membrane of more than 90 percent of all prostate cancers. It also is found on the ...

RainEarth Obtains Patent Approvals for Its Core Technology

... blended PES hollow fiber dialysis membrane -- Synthetic hollow fiber membrane continuous spinning device -- Hollow fiber membrane porous spinneret component -- Hollow fiber tube-in-orifice spinneret ...

Smoking more than 5 cigarettes a day provokes migraine attacks

... control headaches. Migraine sufferers are born with ion channels in the membrane of the neurons which are much more permeable and excitable. The brain of ... are already known to be responsible for the hyperexcitabilty of these membrane ion channels. ...

The microbial hydrocarbon diet

... The team has now found that enzymes within the microbial cell and in its membrane inner membrane are responsible for degradation of n-hexadecane. The team found that ...

Closer to an effective treatment for gum disease in smokers

... the bacterium Porphyromonas gingivalis adapts and changes its DNA and membrane proteins in response to cigarette smoke. Several genes of P. ... smoke. As a result, the expression of a number of the proteins in the cell membrane is changed. This affects important characteristics of the bacterial cells ...

Researchers Tackle CLL, Diabetes and Trauma-Hemorrhage

... Different Responses to Pro-Angiogenic Factors in the Chorioallantoic membrane Assay”, and “Estradiol’s Salutary Effects on ... Different Responses to Pro-Angiogenic Factors in the Chorioallantoic membrane Assay Giovana Di Marco, Etienne Larger and colleagues can be reached at ...

Completely novel action of insulin unveiled

... by moving glucose transporter proteins from inside the cell to the surface membrane so that they can pump glucose into the cell. Myo1c aids in this process by ... healthy people, around 80% of the glucose transporters migrate to the cell membrane after a meal, allowing plenty of glucose into the cell. In people with ...

Membrane fusion at the synapse: Janus faced synaptotagmin-1 helps to keep the fast pace

... of tiny neurotransmitter-filled bubbles called vesicles with the wall membrane of a neuron. This action allows signals to flow between neurons. In a ... from one neuron to another requires the fusion of the vesicle's membrane with its host plasma membrane. This allows the neurotransmitter to diffuse ...

The APCs of nerve cell function

... at the synapse and coordinates their functions in directing the surface membrane delivery and stable retention of nicotinic acetylcholine receptors at the ... directs the delivery of acetylcholine receptors to restricted surface membrane regions. APC and EB1 interact with other proteins, cytoskeletal regulators ...

A new way to think about Earth's first cells

... approximately 3.5 billion years ago. The protocell's fatty acid membrane allows chemical compounds, including the building blocks of DNA, to enter ... and the pH of their environment, micelles can convert into layered membrane sheets or enclosed vesicles. Researchers commonly use vesicles to model ...

DFG establishes 8 new Collaborative Research Centers

... life processes. This is why membranes are equipped with an abundance of membrane proteins, which control and regulate these functions. Malfunctions in the ... intends to understand the precise structures, mechanisms and functions of membrane proteins and thereby create, among other things, the foundations for new ...
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