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Malignant in Medical News

Study provides documentation that tumor 'stem-like cells' exist in benign tumors

... been implicated in the genesis of a variety of malignant cancers. Research scientists at Cedars-Sinai ... seen as a possible strategy in the fight against malignant and benign tumors. Cells generated from the ... earlier findings in cancer stem-like cells of malignant brain tumors, the tumor stem cells but not the ...

New piece found in colorectal cancer puzzle

... the expression of inhibitors of the enzyme with malignant cellular behavior. Lotte Vogel, from the ... PN-1, coincides with the acquisition of malignant properties in colorectal tissue". The ... activity via up regulation of PN-1 is causing the malignant progression or if it is a consequence of it". ...

Delivering Chemo Directly Into Brain Tumors Shows Promise

... Survival times for those with malignant gliomas increased, study found ... in early clinical trials, researchers report. malignant gliomas are difficult to treat using standard ... Only about 3 percent of patients diagnosed with a malignant glioma survive five years or more, according to ...

Can EUS elastography help distinguish benign from malignant tissue?

... The differential diagnosis between benign and malignant lymph nodes and focal pancreatic masses based on ... and measure tissue elasticity. Knowing that malignant tissues are generally harder than normal ... information to help distinguish benign from malignant tissue based on their specific tissue ....

New strategy developed to diagnose melanoma

... a technique to distinguish benign moles from malignant melanomas by measuring differences in levels of ... genes that were present at different levels in malignant melanomas compared to benign moles. They narrowed ... strikingly different between the benign and the malignant tissue, providing an additional trait valuable ...

Also in the March 24 JNCI

... infected normal diploid fibroblasts and malignant glioma cells with HCMV or introduced a copy of ... induced telomerase expression in both normal and malignant human cells. Introduction of the viral IE-72 gene ... is of possible relevance for both (initiation of) malignant transformation and oncomodulation by HCMV ...

A new measure for the malignancy of melanoma

... a growth factor called angiopoietin-2 (Ang2) in malignant melanoma. The docking station of Ang2 is the ... of vascularization and, thus, to strengthen its malignant properties. "Ang2 is a very promising candidate," ... the tumor's blood supply, but also reduce its malignant growth. ...

European Commission and United States Food and Drug Administration (FDA) Both Approve New Options for Patients With Certain Primary Brain Tumors

... as monotherapy, and for patients with malignant gliomas, such as GBM or anaplastic astrocytoma ... needs and patient convenience." About malignant Gliomas The worldwide incidence rate of primary malignant brain and central nervous system tumors, using ...

FDA Clears Cellectar's IND Application for Lead Drug Candidate

... to its selective retention and accumulation in malignant cells versus nonmalignant cells. Preclinical ... (131)I-CLR1404 significantly slowed the growth of malignant solid tumors and resulted in improved survival. ... radioisotopes that can either image or destroy malignant cells. Cellectar's products' unique mechanism of ...

Cell microenvironments hold key to future stem cell therapies

... even impose phenotypically normal behavior on malignant cells during tissue genesis. All of this points ... pathways might be used to "normalize" malignant breast cells. "Normal and malignant mammary epithelial cells in 3-D cultures have ...

A Stage IV Malignant Melanoma Drug That Increases Overall Survival Would Earn a Higher Patient Share in the U.S. Than in Europe

... Resources' Clinical Gold Standard for Stage IV malignant Melanoma in 2012, According to a New Report from ... issues, finds that a drug for treating stage IV malignant melanoma that can increase median overall ... oncologists. The new report entitled malignant Melanoma (Stage IV): Emerging Therapies Must ...

Late-breaking data to be presented at the American Society of Hematology Annual Meeting

... MPL defects cause the overproduction of mature malignant blood cells, but multiple lines of evidence ... of patients (85 percent) had an overproduction of malignant cells mainly dependent on the late stages of ... percent) had an early expansion of very immature malignant progenitor cells, close to the stem cell. ...

Benign or cancerous?

... will describe new advances in the fight against malignant melanoma at a Doctoral Inaugural Lecture to be ... types of 'Spitzoid' melanocytic tumours and malignant melanoma He said: "Malignant melanoma is a ... whether the tumour is a benign 'mole' or a malignant melanoma. Nowhere is this more acute than in the ...

Caffeine Consumption Doesn't Raise Overall Breast Cancer Risk

... considered to be a risk factor for developing the malignant form of the disease, this finding had raised concerns that caffeine might also elevate the risk for malignant breast cancer. To explore this possibility, ... a "borderline significantly increased risk" for malignant disease. A similar positive link was found ...

Hodgkin lymphoma -- new characteristics discovered

... form of cancer of the lymphatic system. The malignant cells are derived from white blood cells (B ... the B cells. They noticed, however, that the malignant Hodgkin/Reed-Sternberg (HRS) cells of Hodgkin ... alternative signaling pathways to maintain their malignant growth. As Dr. Mathas explained, "Reprogramming ...

Normal Cells May Predict Cancer Virulence

... Finding suggests that treatment that only aims at malignant cells might fall short THURSDAY, ... when the tumor is formed whether it is highly malignant or not. Moreover, since the characteristic might ... finding implies that treatments that only target malignant cells may not be effective. So far, however, ...

Cancer research highlights

... proliferation is one characteristic of highly malignant tumors. Song and colleagues found no major ... differences in the morphology of DCIS and other malignant and benign breast lesions, and in their response ... resonance imaging (MRI) scans. For example, malignant and benign breast lesions vary in the rates at ...

Protein Gives Doctors New Tool to Detect Melanoma

... that IMP-3 is an important progression marker in malignant melanoma," study author Dr. Jennifer G. Pryor, a ... to play a role in the formation of number of malignant tumors. Previous studies have linked expression ... American Academy of Dermatology has more about malignant melanoma . -- Robert ...

Faces of Mesothelioma; Meso Foundation Press Conference with Families and Patients

... three-day 5th Annual International Symposium on malignant Mesothelioma, sponsored by the Mesothelioma ... day of the three day International Symposium on malignant Mesothelioma. The press conference is ... exposure -- most often occurring as malignant mesothelioma. In the past eight years since the ...

Sen. Kennedy Up and Walking After Brain Tumor Surgery

... for what doctors say is a life-threatening malignant glioma TUESDAY, June 3 (HealthDay ... three-and-a-half-hour surgery to treat his malignant brain tumor. The 76-year-old Kennedy was ... reported. Kennedy underwent surgery for a malignant glioma, an especially lethal type of brain tumor. ...

Sen. Kennedy's Brain Tumor Surgery Called a 'Success'

... for what doctors call a life-threatening malignant glioma MONDAY, June 2 (HealthDay ... three-and-a-half surgery to treat his malignant brain tumor. "I am pleased to report that ... The 76-year-old senator underwent surgery for a malignant glioma, an especially lethal type of brain tumor, ...

Sen. Kennedy Undergoing Surgery for Brain Tumor

... He has a malignant glioma, an especially lethal type of brain tumor ... M. Kennedy was undergoing surgery Monday for the malignant brain tumor that was diagnosed last month. The 76-year-old senator was having the surgery for a malignant glioma, an especially lethal type of brain tumor, ...

Ted Kennedy Released From Hospital

... home while doctors determine treatment plans for malignant brain tumor WEDNESDAY, May 21 ... one day after it was revealed that he has a malignant brain tumor. With a square bandage at the back ... performed a biopsy that led to the diagnosis of a malignant glioma, Kennedy flashed a thumbs-up sign to ...

Ted Kennedy Has a Brain Tumor

... Doctors find malignant glioma in tests after seizure ... brother in an American political dynasty, has a malignant brain tumor, his doctors reported Tuesday. ... brain identified the cause of the seizure as a malignant glioma, the Associated Press reported. Dr. ...

Genetic Disorder May Hold Key to Heat Stroke Cure

... and the genetic and protein defects that cause malignant hyperthermia (MH), an inherited condition that ... muscle breakdown in humans are related to malignant hyperthermia as well," Henry Rosenberg, president of the malignant Hyperthermia Society of the United States, said ...

Radiologists use special MRI to identify brain cancer early

... by perfusion MRI precede other markers of malignant transformation by a year or more, said study ... volume (rCBV) changes are an indicator of future malignant transformation. Brain tumors can bring about ... years. Seven patients progressed to high-grade, malignant gliomas between six and 36 months. In the six ...

Cancer theory stands the test of time -- rediscovering Boveri a century later

... Boveris 1914 monograph Concerning the Origin of malignant Tumours . Out of print for decades and previously ... of Biologists. Concerning the Origin of malignant Tumours had a huge impact on cancer research. In ... only English version of Concerning the Origin of malignant Tumours ever available before was a rare ...

PET outperforms CT in characterization of lung nodules

... and characterizing SPNs is important because malignant nodules represent a potentially curable form of ... Identifying which SPNs are most likely to be malignant enables physicians to initiate the proper therapy ... modality, and their determination of benign and malignant nodules were compared to pathologic findings or ...

Less invasive methods may provide accurate means to determine lung cancer stage

... who met all study criteria, 42 (30 percent) had malignant lymph nodes. The researchers found that ... vs. 36 percent), detecting 29 (vs. 15) of the 42 malignant lymph nodes. EUS plus EBUS had higher estimated ... alone, the combination identified 10 more malignant lymph nodes, with sensitivity estimated to be 24 ...

Researchers find less invasive, highly accurate methods

... and sides, was 93 percent accurate in finding malignant lymph nodes in a group of 138 patients. This is ... their study. Both scopes together found more malignant lymph nodes than did the use of a single ... was no evidence of cancer spread. In all, 42 malignant lymph nodes were found in the patients. The ...

Melanomas may appear noticeably different than other moles

... one of the JAMA/Archives journals. Rates of malignant melanoma continue to increase, and early ... pigmented skin lesions is to distinguish between malignant melanoma and benign simulants, the authors write. ... identified them as ugly ducklings. The malignant melanomas were apparent as being different to at ...

Chemoprevention, naturally: Findings on plant-derived cancer medicines

... shows promise in preventing or slowing the malignant transformation of precancerous oral lesions. ... untreated precancerous oral lesions will undergo malignant transformation into squamous cell cancer, but we ... proteins closely correlated with inflammation and malignant progression. Following treatment, Mallery says, ...

Early Results of Phase 2 Trial of Perifosine (KRX-0401) for the Treatment of Recurrent Malignant Gliomas Presented at the 12th Annual Scientific Meeting of Society for Neuro-Oncology

... II Trial of Perifosine for Recurrent/Progressive malignant Gliomas, provided an update on the clinical activity of single agent perifosine in patients with malignant glioblastoma (GBM) and malignant anaplastic gliomas (AA). Ph II Study - Interim ...

Sound medicine at Acoustics Meeting

... often ambiguous and cannot differentiate between malignant and benign thyroid nodules. The overwhelming ... may reveal a more definitive diagnosis. malignant lesions are stiffer than benign lesions; ... and Asia for treating people with a variety of malignant tumors, and several major clinical trials are ...

A fresh look at existing therapies: Researchers explore ways to teach approved drugs new tricks

... targeting two different receptors on the malignant cells, when the receptors have different ... Cancer Center. This also suggests that if the malignant cells become refractive to one antibody, the ... was shown to be a survival factor in certain malignant cells, chronic lymphocytic leukemia, she said. So ...

Diet and medications may assist prevention of prostate cancer

... to studies that suggest prostate cells become malignant in men in their 20s and 30s and conclude , ... underway to evaluate whether this drug prevents malignant biopsies in men with elevated prostate surface ... pathways that develop, sustain and progress malignant cells in the prostate will be critical in the ...

T vs. B: Re-engineered human T cells effectively target and kill cancerous B cells

... white blood cells, engineered to recognize other malignant immune cells, could provide a novel therapy for ... cells, but it has a difficult time recognizing malignant cells since they largely appear normal to the ... system, to recognize and attack infected or malignant cells. This chimeric gene, formed from active ...

Long-term health and social outcomes for neuroblastoma survivors

... in the Childhood Cancer Survivor Study (CCSS). Late mortality, second malignant tumors, and chronic health conditions were analyzed. The researchers also ... factors for long-term complications of neuroblastoma treatment and second malignant neoplasms" In an accompanying editorial, Elizabeth Fox, M.D., of the ...

NeoGenomics Enters into Strategic Supply Agreement with Abbott for Development of a Melanoma Cancer Test

... NeoGenomics intends to develop a FISH test to distinguish benign versus malignant melanoma. The goal for the new test is to provide the ability to more accurately diagnose malignant melanoma and provide more accurate prognostic information, thus assisting ...

Tips from the journals of the American Society for Microbiology

... Inhibits Deadly Skin Cancer in Mice A new DNA vaccine inhibited malignant melanoma, a deadly form of skin cancer, in mice by eliciting antibodies ... DNA vaccine suggest a novel approach against various cancers, especially malignant melanoma." (J. Fang, Y. Lu, K. Ouyang, G. Wu, H. Zhang, Y. Liu, Y. ...
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