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Lipoprotein in Medical News

Lipoprotein Levels May Predict Women's Hypertension Risk

... Nov. 11 (HealthDay News) -- High levels of lipoprotein particles may increase the risk of high blood ... of participants in the Women's Health Study. lipoprotein particles carry cholesterol and triglycerides ... imaging to determine the number and size of lipoprotein particles can better predict a woman's risk of ...

Little-Known Fat Can Be a Heartbreaker

... Elevated lipoprotein (a) levels boost cardiovascular disease risk for ... aren't too high. But, do you know what your lipoprotein (a) levels are? Well, if you don't have a ... you probably don't need to know how much lipoprotein (a) is lurking in your blood. But, if any ...

SpectraCell Laboratories Offers Additional Test for Heart Attack and Stroke Risk

... to modify treatment strategies determined by lipoprotein particles alone." Since stroke is the leading ... test is often used in conjunction with advanced lipoprotein tests. SpectraCell's LPP+(TM) combines ... LPP(TM) testing is the most advanced lipoprotein test available. Unlike traditional cholesterol ...

One-Third of U.S. Primary Care Physicians and Cardiologists Do Not Currently Prescribe Treatment to Meet HDL Cholesterol Targets as Recommended By National Guidelines

... consider it necessary to treat low high- density lipoprotein (HDL) until patients' HDL levels drop below the ... low cost and efficacy in reducing low-density lipoprotein (LDL) cholesterol or high triglycerides in ... and scientific factors. About High-Density lipoprotein Cholesterol Patients with low levels of HDL ...

Scientists look at 'syringe' assembly in plague bacteria

... scientists thought that the position of a key lipoprotein component of the syringe was determined by one or ... identified sorting signals. The YscJ lipoprotein in Yersinia pestis is an essential part of the ... a few key amino acids, the location of the YscJ lipoprotein is determined by the presence of a specific ...

NIH awards $10.8M to Columbia to study connection between diabetes and heart disease

... of lipoproteins, such as very low-density lipoprotein (VLDL) and low-density lipoprotein (LDL, often called bad cholesterol), in ... This will offer clues as to how high atherogenic lipoprotein levels contribute to heart disease in people with ...

Soyfoods a Healthy Choice for Men

... both the total amount of cholesterol and the so-called "bad" low-density lipoprotein (LDL) cholesterol. In addition, soy protein may also help maintain or moderately increase the "good" high-density lipoprotein (HDL) cholesterol, (6) and may help lower triglycerides, which both are ...

Two Studies at AACE 2009 Annual Meeting Highlight Effects of Welchol(R) (colesevelam HCl) on Blood Glucose and LDL-C in Patients with Type 2 Diabetes

... as an adjunct to diet and exercise to: - reduce elevated low-density lipoprotein cholesterol (LDL-C) in patients with primary hyperlipidemia (Fredrickson ... Accessed April 8, 2009. 6) Brunzell JD, Davidson M, Furberg CD, et al. lipoprotein management in patients with cardiometabolic risk: consensus statement from ...

New target for maintaining healthy blood pressure discovered

... and in ones that contained an additional mutation in the low-density lipoprotein receptor gene. These manipulations effectively rendered the mice unable to ... were smaller and less abundant in mice that had both the low-density lipoprotein and PG F2-alpha receptors knocked out, as was macrophage infiltration and ...

JCI online early table of contents: April 13, 2009

... is vital to the development of atherosclerosis; however, the method of lipoprotein uptake in vivo remains poorly defined. In a new study, Howard S. Kruth and ... The authors therefore conclude from these results that targeting lipoprotein pintocytosis should be considered when developing novel atherosclerotic ...

Saving Money While Protecting Your Health in Tough Economic Times

... tests had failed to find. The diagnostic assesses the number of lipoprotein particles in the blood -- which, if the number becomes too high, triggers ... the NMR LipoProfile test ( www.lipoprofile.com ) to identify patients with lipoprotein markers that are common in people with metabolic syndrome and insulin ...

Most heart attack patients' cholesterol levels did not indicate cardiac risk

... cholesterol guidelines. Specifically, these patients had low-density lipoprotein (LDL) cholesterol levels that met current guidelines, and close to half ... half of patients hospitalized for a heart attack had poor high-density lipoprotein (HDL) cholesterol levels, according to national guidelines. ...

Synthetic HDL: A new weapon to fight cholesterol problems

... scientists now offer a promising new weapon -- synthetic high-density lipoprotein (HDL), the "good" cholesterol -- that could help fight chronically high ... main protein component of naturally occurring HDL. The final high-density lipoprotein nanoparticles are each about 18 nanometers in diameter, a size similar to ...

BioIQ and Alere to Provide At-Home Biometric Screening Tests to Employees

... to a certified laboratory for analysis. Measurements include high-density lipoprotein (HDL), low-density lipoprotein (LDL), total cholesterol, triglycerides, hemoglobin/A1c, and fasting ...

Triglyceride Levels Continue to Rise in the United States Despite Increased Use of Cholesterol-Lowering Medications

... by blood levels of total cholesterol, triglycerides, high density lipoprotein (HDL) cholesterol and low density lipoprotein (LDL) cholesterol. HealthCore, a subsidiary of WellPoint, is a health ...

Cholesterol-lowering drugs may also lower PSA, but whether they cut cancer risk is still not known

... the blood; when the level of so-called "bad" cholesterol, or low density lipoprotein (LDL) is too high and concentrations of "good" cholesterol, or high density lipoprotein (HDL) too low, it can lead to cardiovascular disease. ...

SpectraCell Laboratories Expands Operations in New Facility

... need to be corrected. SpectraCell's LPP(TM) tests are the most advanced lipoprotein tests available. Unlike traditional cholesterol tests, SpectraCell's LPP(TM) directly measures the number of several classes of lipoprotein particles providing an accurate assessment of cardiovascular risk. ...

Innovative diabetes program in Bloomington-Normal, Ill., a success

... HbA1c (a test indicating the level of blood sugar control), low-density lipoprotein (LDL)-cholesterol, an eye exam, and screening for kidney disease. More ... percentage points. Seventy-six percent were screened for low-density lipoprotein (LDL), up 14 percentage points over 2006. The rate of LDL control ...

Innovative Diabetes Program in McLean County a Success

... HbA1c (a test indicating the level of blood sugar control), low-density lipoprotein (LDL)-cholesterol, an eye exam, and screening for kidney disease. More ... percentage points. -- Seventy-six percent were screened for low-density lipoprotein (LDL), up 14 percentage points over 2006. The rate of LDL control ...

Blood cholesterol levels predict risk of heart disease due to hormone therapy

... women who had no history of heart disease but whose ratio of low-density lipoprotein (LDL or bad) cholesterol to high-density lipoprotein (HDL, or good) cholesterol was less than 2.5 were at no increased risk of ...

Grapefruit Compound Inhibits Hepatitis C Virus

... Recent research suggests that HVC may be "hitching a ride" along the lipoprotein life cycle, and that compounds and dietary supplements that influence lipoprotein metabolism may also affect HCV. In this new study, researchers ...

Welchol(TM) Added to the American College of Endocrinology/American Association of Clinical Endocrinologists 'Road Maps to Achieve Glycemic Control in Patients with Type 2 Diabetes Mellitus'

... and only medication approved to reduce both glucose levels and low density lipoprotein cholesterol levels (LDL-C). Marketed since 2000, Welchol, a bile acid ... as an adjunct to diet and exercise to reduce elevated low-density lipoprotein cholesterol (LDL-C) in patients with primary hyperlipidemia (Fredrickson ...

Gene Variants Can Predict Threat of Heart Disease

... levels. The researchers also looked at the participants' high-density lipoprotein (HDL) and low-density lipoprotein (LDL) cholesterol levels, and their subsequent medical histories. The ...

Significant Generic Erosion Will Cause Sales of Dyslipidemia Drugs to Decline by $3.6 Billion by 2016

... therapies that offer dual modes of action and/or modulate high-density lipoprotein (HDL) in addition to low- density lipoprotein (LDL) cholesterol. The fixed-dose combinations class will capture 30 ...

Grapefruit compound may help combat hepatitis C infection

... in Medicine (MGH-CEM) report that HCV is bound to very low-density lipoprotein (vLDL, a so-called bad cholesterol) when it is secreted from liver cells ... showed that the compound inhibits the mechanism for secreting a specific lipoprotein that binds HCV. This work presents the possibility that non-toxic ...

High triglycerides, other cholesterol raise risk of stroke

... brain. Those with high triglycerides and elevated non-high density lipoprotein cholesterol were more likely to have a large artery atherosclerotic stroke ... common type of fat in the blood. Those with the greatest non-high density lipoprotein cholesterol, which is neither the good nor the bad cholesterol, were 2.4 ...

Knowing Heart Risk Keeps Patients on Cholesterol Drugs

... had small but significantly greater reductions in "bad" low-density lipoprotein (LDL) cholesterol levels and their ratio of total cholesterol to "good" high-density lipoprotein (HDL) cholesterol levels, the researchers said. "Patients in the risk ...

Amarin Commences First Clinical Trial in Cardiovascular ProgramAmarin Commences First Clinical Trial in Cardiovascular Program

... can be manifested by elevation of total cholesterol, the "bad" low-density lipoprotein (LDL) cholesterol and triglyceride concentrations, and a decrease in the "good" high-density lipoprotein (HDL) cholesterol concentration in the blood. About metabolic syndrome ...

GlaxoSmithKline Obtains Exclusive U.S. OTC Marketing Rights to MEVACOR(R) (lovastatin) from Merck & Co., Inc.

... 2 aluminum lake. CLINICAL PHARMACOLOGY The involvement of low-density lipoprotein cholesterol (LDL-C) in atherogenesis has been well-documented in clinical ... and elevated LDL-C concentrations. LDL is formed from very low-density lipoprotein (VLDL) and is catabolized predominantly by the high affinity LDL receptor. ...

Researchers study potential health benefits of natural chemicals in muscadine grape seeds

... The study will also measure any effects on total cholesterol, low-density lipoprotein or bad cholesterol, triglycerides, high-density lipoprotein or good cholesterol, blood sugar levels and markers for inflammation, such ...

When 'Good' Cholesterol Goes Bad

... story has been a relatively simple one in which "bad" low-density lipoprotein (LDL) cholesterol formed plaques that eventually blocked arteries, while "good" high-density lipoprotein (HDL) cholesterol worked to carry away those deposits, explained Dr. Jay ...

Use of certain lipid measures not more effective in predicting coronary heart disease

... coronary heart disease (CHD) prevention emphasize the use of low-density lipoprotein cholesterol (LDL-C), total cholesterol, or both for CHD risk assessment. ... of LDL) and lower apo A-I (the primary protein component of high-density lipoprotein [HDL]) levels play a role in the development of CHD, and that these ...

New review suggests caution on drugs to raise 'good' cholesterol

... supports the use of most medications to raise levels of high-density lipoprotein (HDL) good cholesterol. Some are even harmful. The authors concluded that while efforts to lower low-density lipoprotein (LDL or bad cholesterol) have consistently reduced cardiovascular disease ...

Cholesterol Screening Shouldn't Rely on Kids' Weight

... or obese. Since then, a University of Michigan team have examined the relationship between body mass index and total and low-density ("bad") lipoprotein cholesterol. They found that screening all overweight or obese children would identify only about 50 percent of children with abnormal cholesterol ...

FDA Approves LIVALO(R) for Primary Hypercholesterolemia and Combined Dyslipidemia

... to a more effective inhibition of the HMG-CoA reductase enzyme to inhibit cholesterol production, and potentially affords greater low-density lipoprotein cholesterol (LDL-C) clearance and reduction of plasma cholesterol. Importantly, pitavastatin is only minimally metabolized by the liver through the ...

VAP(R) Cholesterol Test Highlighted in Groundbreaking Book on Longevity

... for direct LDL measurement, which is accurate with non-fasting samples. It is the only advanced lipid profile that routinely reports all three lipoprotein parameters considered necessary by the American Diabetes Association and American College of Cardiology expert consensus guidelines. The VAP Test is ...

Genes Linked to Cholesterol in Cells Are Identified

... The 20 genes are likely to be "immediately relevant" for maintaining cholesterol levels in the cell, as well as controlling the uptake of low-density lipoprotein (LDL) cholesterol, the researchers explained in the July 8 issue of Cell Metabolism . "High cholesterol in the blood is considered to be ...

China Pharma Holdings, Inc. Announces SFDA Approval for Rosuvastatin Clinical Trials

... and our shareholders over time." (1) Source: BMJ 2003 June: 326 (7404):1423. Law MR et al. "Quantifying effect of statins on low density lipoprotein cholesterol, ischaemic heart disease, and stroke: systematic review and meta-analysis." (2) Source: AstraZeneca 2007 Annual Report and Form ...

Another Blood Fat Fuels Heart Attack Risk

... infarction with increased levels of lipoprotein(a)," the researchers wrote. The risk was highest in people whose LPA had a smaller number of lipoprotein attachments, they noted. Caution is needed in interpreting the results because all the people in the studies were white, Nordestgaard said. ...

DASH Diet Has Extra Benefits for Women's Health

... Hypertension [DASH] diet may contribute to prevention of heart failure in some cases because it effectively reduced blood pressure and low-density lipoprotein (LDL, or "bad") cholesterol levels in clinical trials," wrote Emily B. Levitan, of Beth Israel Deaconess Medical Center in Boston, and colleagues. ...
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