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Initiation in Medical News

BioMarin Announces Second Quarter 2009 Financial Results

... Upcoming Milestones 3Q09: initiation of PEG-PAL Phase II trial 3Q09: ... 2H09: Decision on 6R-BH4 PAH program 1Q10: initiation of Phase I trial for BMN-195 for DMD 1Q10: ... for existing preclinical candidate 2H10: initiation of pivotal Phase III trial for GALNS for MPS ...

New Data Demonstrate RISPERDAL(R) CONSTA(R) (Risperidone) Long-Acting Treatment May Improve Health Outcomes and Reduce Hospitalizations in Patients with Schizophrenia

... psychiatric hospitalizations after the initiation of RISPERDAL(R) CONSTA(R). This analysis ... between 12 months prior to and 12 months after initiation of RISPERDAL(R) CONSTA(R). Results showed that between the pre- and post- RISPERDAL(R) CONSTA(R) initiation periods, the mean number of psychiatric ...

New Analyses from 16-Year Follow-up Trial with Betaseron(R) Demonstrated that Early and Sustained Treatment of Multiple Sclerosis Patients Enrolled in the Trial Affected Their Long-term Outcomes

... years later.(1) In this study, early initiation and sustained exposure to Betaseron were strongly ... the relationship between timing of drug initiation and exposure and long-term outcomes. ... titration and use of analgesics during treatment initiation may help reduce flu-like symptoms. BETASERON ...

Medarex Highlights Oncology Pipeline at Needham Cancer Therapeutics Conference in New York City

... with the U.S. Food and Drug Administration. initiation of the second-line Phase 3 radiotherapy ... as for rheumatoid arthritis, is expected in 2009. initiation of the Phase 1 trial in acute lymphocytic ... platform to reach clinical testing. Enrollment initiation in the Phase 1 trial for renal cancer remains on ...

Bradmer provides clinical trial update and announces evaluation of strategic alternatives

... market conditions and new projections of site initiation and patient enrollment from the Company's ... trial sites activated and another 15 sites near initiation with regulatory and budgeting processes ... that it is unable to meet the targets for site initiation and enrollment of sufficient patients in a timely ...

Gambia takes on as National Program UAB project to abolish FGM

... girls are at risk of becoming victims of this initiation ritual. According to a 2005 census, more than ... goals of her work, which is the acceptance of the initiation without Mutilation project by the Gambian ... with rites of passage containing similar initiation rituals, which in this case would include the ...

LSUHSC's Dr. Xiao Cheng Wu co-authors annual report to the nation on cancer

... Dakota, Indiana, Michigan, and Iowa. Trends in initiation of smoking among 12-17 year-old adolescents in the United States, 1940 through 2000, show that initiation rates increased sharply in girls from 1965 ... 1990 through the mid-1990s, especially in boys. initiation rates were similar for boys and girls during the ...

New Study Data: JANUVIA™ (sitagliptin) Significantly Reduced Blood Sugar Levels and Was Not Associated with Hypoglycemia in Elderly Patients with Type 2 Diabetes

... of renal function is recommended prior to initiation of JANUVIA and periodically thereafter. ... occurred within the first three months after initiation of treatment with JANUVIA, with some reports ... of renal function is recommended prior to initiation of JANUVIA and periodically thereafter. ...

CAPHOSOL results in minimal oral mucositis and pain in head/neck cancer patients

... (ONS), demonstrate that use of CAPHOSOL from the initiation of cancer treatment results in a low incidence of ... therapy for head and neck cancer. From the initiation of cancer therapy, breakdowns begin to occur ... can usually be seen within seven to 14 days after initiation of therapy. Initial signs and symptoms include ...

Accuracy, efficacy and ethics of abstinence-only programs questioned by public health experts

... in its primary goal of helping young people delay initiation of sex, and actually, withholds life-saving ... found that most abstinence programs did not delay initiation of sex and only 3 of 9 had any significant ... people's sexual behavior, including both delaying initiation of sex and increasing condom and contraceptive ...

JCI online early table of contents: June 12, 2008

... were screened for their ability to inhibit the initiation of translation by modifying the function of a ... that developing approaches to inhibit translation initiation by targeting eIF4A might provide a way to ... TITLE: Therapeutic suppression of translation initiation modulates chemosensitivity in a mouse lymphoma ...

Cardium Reports on Recent Highlights and Financial Results

... Highlights and Recent Developments -- initiation of Phase 2b MATRIX clinical trial to evaluate the ... expected to be announced in late 2008. -- initiation of Phase 3 AWARE trial for Generx(TM), a ... within three hours of an acute stroke. -- initiation of pre-clinical studies supported by an NIH Small ...

Isis Reports Financial Results and Highlights for Fiscal year 2007

... mipomersen. Earlier in the year, we announced the initiation of the Phase 3 studies in patients with ... $1.25 million milestone payment in equity for the initiation of this study. Partnership Highlights ... drug in this franchise, to Genzyme and the initiation of Phase 3 studies of mipomersen in patients ...

Lutonix, Inc. Announces First Patient Enrollments in Three Separate Clinical Trials

... scientific evidence collected from this investigation will support the initiation of large global trials in the near future," she added. Prof. Mathey ... of Angiology at the Park-Krankenhaus in Leipzig, Germany states, "The initiation of the LEVANT I study is a major milestone and I am honored to lead such ...

Both good/bad movie characters who smoke influence teens to do the same

... "Previous studies have confirmed a link between smoking in movies and the initiation of smoking by adolescents, and we wanted to dig deeper into the data to ... contain smoking, parents should talk with them in an effort to discourage initiation of smoking." ...

Sofinnova Partners Leads Investment Round in CoAxia

... of NeuroFlo in combination with a variety of stroke devices and drugs, and initiation of marketing. Antoine Papiernik, Managing Partner at Sofinnova ... that we are now well positioned for trial completion, PMA submission and initiation of sales and marketing." Sofinnova, since its founding in 1972, has ...

Phase 1 Study Initiated with Micromet Anti-GM-CS Human Antibody MT203

... of cancer, inflammation and autoimmune diseases, today announced the initiation of the first clinical trial for the anti-granulocyte macrophage ... development and commercialization of MT203 going forward. "The initiation of the first clinical trial represents a major milestone for MT203," ...

Abbott Initiates Trial of Next-Generation XIENCE PRIME(TM) Drug Eluting Stent, Building Upon Superior Outcomes from SPIRIT Family of Trials

... 16 /PRNewswire-FirstCall/ -- Abbott (NYSE: ABT ) today announced the initiation of SPIRIT PRIME, a clinical trial to study the performance of the ... the superior outcomes from the SPIRIT family of clinical trials, and the initiation of the study represents Abbott's commitment to bringing important advances ...

FDA Approves SAMSCA(TM) (tolvaptan), the First and Only Oral Vasopressin Antagonist to Treat Patients With Clinically Significant Hypervolemic and Euvolemic Hyponatremia

... to standard of care for at least 7 days), were administered SAMSCA. Upon initiation of therapy, average serum sodium concentrations increased to approximately ... of Serum Sodium Can Cause Serious Neurologic Sequelae - During initiation and after titration monitor patients to assess serum sodium concentrations ...

Protein that suppresses androgen receptors could improve prostate cancer diagnosis, treatment

... that signaling by the androgen receptor is paramount for not only the initiation but also the progression of the disease, including escape to a ... their activity. "You could make the leap and say perhaps prostate cancer initiation and progression may be regulated by expression or non-expression of these ...

Transition Therapeutics Announces Third Quarter Fiscal 2009 Financial Results

... TT-223 - Diabetes: - On March 23, 2009, Transition announced the initiation of a Phase Ib clinical study of TT-223 in combination with a GLP-1 ... patients in February 2009. On March 23, 2009, Transition announced the initiation of a Phase Ib clinical study of TT-223 in combination with a GLP-1 ...

Micromet, Inc. Reports First Quarter 2009 Financial Results

... with a major pharmaceutical company to develop a new BiTE antibody, the initiation of a new phase 2 clinical trial for adecatumumab (MT201), the filing of a ... On March 23, Micromet announced the initiation of a new phase 2 clinical trial with its human anti-EpCAM IgG1 antibody ...

Aplenzin(TM), the Only Single Tablet Once-Daily Treatment for Depression at All Doses, Now Available in the United States

... 14 days should elapse between discontinuation of an MAO inhibitor and initiation of APLENZIN. Physicians should be aware that bupropion is associated ... restlessness, agitation, anxiety, and insomnia, especially shortly after initiation of treatment, have been associated with treatment with bupropion. ...

GSK Submits TYVERB(R)/TYKERB(R) (lapatinib) for First-Line Treatment of Metastatic Breast Cancer in Europe, US

... is uncertain. The hepatotoxicity may occur days to several months after initiation of treatment. Liver function tests should be monitored before initiation of treatment, every 4 to 6 weeks during treatment, and as clinically ...

Bradmer announces 2008 fourth quarter and fiscal year operational and financial results

... ART Trial to further patient enrollment due to unforeseen delays in site initiation and recruitment, the delayed ability to complete the 60 patient "run-in ... in cash was due to funds spent on production of Neuradiab, on site initiation and patient enrollment. The Company expects that cash on hand at December ...

Alcohol-Branded Apparel Linked to Adolescent Drinking

... drink, McClure said. "But it is also a direct link with susceptibility and initiation to drinking," she said. "You can't say any longer that these items are ... putting these products in the hands of children. "Preventing the early initiation of alcohol use is critical for our kids," Jernigan said. "We have a ...

Medarex Announces 2008 Fourth Quarter and Year End Financial Results

... as compared to placebo treatment. Advancing our pipeline with the initiation of Phase 2 trials for the MDX-1100 anti-IP10 antibody for the treatment of ... Inc., announced in August 2008. Advancing our pipeline with the initiation of Phase 1 oncology trials for the MDX-1411 anti-CD70 antibody for the ...

Arena Pharmaceuticals Announces Initiation by Merck of Phase 2 Clinical Trial of Niacin Receptor Agonist

... -- Arena Pharmaceuticals, Inc. (Nasdaq: ARNA ) announced today the initiation of a Phase 2 clinical trial of an orally administered niacin receptor ... the "good" cholesterol, similar to the therapeutic action of niacin. The initiation of this trial does not trigger a milestone payment. The Phase 2 ...

Shionogi Announces Positive Top-Line Efficacy Results from Year-Long Studies of Velneperit, a Novel NPY Y5 Receptor Antagonist Being Investigated for the Treatment of Obesity

... in which subjects lost 7.1 kg of their baseline body weight taken at the initiation of the fixed low calorie diet, versus 4.3 kg for the placebo/placebo group ... NPY is an orexigenic signaling molecule that plays a role in meal initiation and regulation of energy balance, and is believed to be especially ...

ViroPharma Reports Results of Phase 3 Clinical Trial for Maribavir in Bone Marrow Transplant Patients

... (P=0.79). The first of four key secondary endpoints was the rate of initiation of anti-CMV treatment within 6 months, which was 37.9 percent for ... benefit of maribavir. These key secondary endpoints include incidence of initiation of preemptive anti-CMV therapy, incidence of graft-versus-host disease, ...

Patients starting Parkinson's drug rasagiline earlier do better

... extension study hold up under further scrutiny, it may indicate that early initiation of rasagiline confers a protective effect against disease progression, Dr. ... treated as soon as possible." The study authors point out that early initiation of any drug to relieve symptoms of Parkinson's disease may lead to a ...

5 Brown faculty elected to world's largest scientific body

... She was recognized for her ongoing research. Her lab is studying the initiation of DNA replication (doubling of the hereditary information of the cell), ... suggests that a steroid hormone receptor may play a direct role for initiation of DNA replication, which could help clarify the role certain hormones ...

GlaxoSmithKline and Dynavax Announce Worldwide Strategic Alliance : – Developing First-in-Class Endosomal TLR Inhibitors for Autoimmune and Inflammatory Diseases –

... business, including difficulties or delays in discovery or development, initiation and completion of preclinical or clinical studies, the results of those studies and the impact of those results on the initiation and completion of subsequent studies and issues arising in the regulatory ...

Combination of TYKERB(R) (lapatinib) Plus Letrozole Demonstrated Significant Improvement in Delaying Disease Progression for HER2+/ErbB2+ Post-Menopausal Metastatic Breast Cancer

... is uncertain. The hepatotoxicity may occur days to several months after initiation of treatment. Liver function tests should be monitored before initiation of treatment, every 4 to 6 weeks during treatment, and as clinically ...

Nuvelo Reports Third Quarter 2008 Financial Results

... of the merger transaction with ARCA by the end of 2008 or early 2009; -- initiation of a Phase 2 trial with NU172 in CABG procedures in the fourth quarter of ... the Phase 1 SAD trial with NU206 in healthy volunteers in 2008; and -- initiation of a Phase 1b multiple ascending dose (MAD) trial with NU206 in healthy ...

Statin use associated with reduction in prostate specific antigen levels

... in PSA, the investigators compared PSA values taken up to two years before initiation of statin therapy and PSA values measured within one year after initiation of statin use. The researchers saw a median decline in PSA of 4.1% and ...

Cleveland Clinic Launches Fully Dedicated International Comprehensive Critical Care Program

... Clinic continues to put patients first. This expansion allows the initiation of Cleveland Clinic care upon the arrival of our teams and ensures the ... referring physician. We provide a seamless transition of care and on-scene initiation of Cleveland Clinic treatment." The program will offer uninterrupted ...

Micromet, Inc. Reports Second Quarter 2008 Financial Results

... a milestone payment of $775,000 from Nycomed in connection with the initiation of formal preclinical safety studies for antibody MT203, which has ... inflammatory and autoimmune diseases. In April, Micromet announced the initiation of the first phase 1 clinical trial with its BiTE antibody MT110. The ...

Clinical Trial for the Treatment of Inflammatory Bowel Disease Begins at Tel Aviv Sourasky Medical Center

... and other proteins to address major diseases, today announces the initiation of a clinical trial with top clinical scientists at Tel Aviv Sourasky ... during the conduct of the trial itself. In addition to the initiation of this IBD study, Anadis recently announced being awarded a VISTECH grant ...

Lorillard Tobacco Company Comments on Harvard School of Public Health Report

... controls or alters the menthol levels in its products to promote smoking initiation or addiction is categorically false. Lorillard does not control levels ... Lorillard does not engineer any of its cigarettes to promote smoking initiation or nicotine addiction. Importantly, the target menthol specifications for ...
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(Date:8/28/2014)... for delivering compounds that could positively impact ... may be possible, thanks to researchers in ... semi-soft vaginal suppository made from the seaweed-derived ... antiviral drug Tenofovir provides a woman-initiated, drug-delivery ... of sexually transmitted infections during unprotected heterosexual ...
(Date:8/28/2014)... August 28, 2014 Dyslexia, the most commonly ... a neurological reading disability that occurs when the ... don,t function normally. , The use of non-invasive ... activity is disrupted in dyslexia. However, most prior ... of brain regions, leaving a gap in our ...
(Date:8/28/2014)... the first person to alert the world to Global ... be captured and stored underground. He says that Carbon ... the best way to avoid global warming getting out ... (Columbia University, New York) made the call during his ... where 150 scientists are meeting to discuss Carbon Capture ...
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(Date:8/30/2014)... Saturday 30 August 2014: The first comprehensive ESC ... presented at ESC Congress 2014 by Task Force Chairpersons ... , The "2014 ESC Guidelines on the diagnosis and ... European Heart Journal (1) and on ... recommendations were published in 2001 but they were restricted ...
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