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Inheritance in Medical News

ASHG hosts fourth annual DNA Day essay contest, supports genetics education efforts

... an insightful description of a variety of inheritance patterns that go beyond the 'either/or' types ... all traits come in just two varieties. Modes of inheritance like co-dominance, incomplete dominance, and ... will probably uncover even more complex modes of inheritance and relationships between genes and traits that ...

Study looks at mitochondrial variation in sperm traits and sperm competitive ability

... in the field of sexual selection, where maternal inheritance of mitochondria may well have its greatest ... gap in evaluating the importance of maternal inheritance of mitochondria for sexual selection and male ... The fundamental insight that strict maternal inheritance of mitochondria constrains the ability of males ...

Contracts adding legal twist to family health care

... said. "After all, if they provide care on a casual basis and then get an inheritance when their relative dies, this money would be tax free." But Kaplan ... limit tax consequences if the Internal Revenue Service ever challenged an inheritance by claiming that the funds stemmed from services provided to the deceased. ...

Polycystic ovarian syndrome: New light on its causes and its effect on brothers

... with PCOS for insulin resistance and lipid levels to collect more data from a larger group. "At this stage we would hesitate to say that a genetic inheritance is definitely playing a role in the increased risk of insulin resistance and other, related conditions in these brothers. We need to explore the ...

Wistar Institute team finds key target of aging regulator

... like this acetylation on histone H4 lysine 16, are persistent and are maintained through generations of cell divisions. This DNA-independent inheritance is called epigenetics," Berger says. "Characteristic epigenetic features have been discovered for various developmental processes in recent years. ...

Hospital Car Parking Fees Top the List of Life's Biggest Injustices

... reveals that taxes are the UKs most contested charges when combined, with over a third of people (39 per cent) believing that they are unfair. inheritance Tax came second on the public's unfair hit list, closely followed by Council Tax third, while tax on savings, National Insurance and Road Tax all ...

Brain Anatomy Could Point to Autism

... eye contact," Shaw said. Piven's study comes on the heels of a report published online last week in the journal Nature that found that the inheritance of abnormal mutations of two common genes can raise the risk for developing autism. More information For more about autism, visit the U.S. ...

23andMe Launches Free Online Community for Moms and Moms-to-Be

... -- If relatives are genotyped as well, members can build a genetic family tree and see how their genes and traits have been passed down. inheritance Calculator -- Couples can see from their own genomes the possibilities of their child's traits, such as eye color. Research -- Members can ...

Gene Mutation Linked to Inherited ALS

... in a gene that interacts with biological pathways already implicated in ALS and other neurological diseases, resulting in familial ALS of differing inheritance patterns and varying severity," Dr. Thomas Kwiatkowski, of the Institute for Neurodegenerative Disease at Massachusetts General Hospital and lead ...

What Moms Learned May Be Passed to Offspring

... cells called long-term potentiation (LTP), which is believed to be involved in learning and memory. "This is the first study to demonstrate an inheritance of a change in a signaling pathway that promotes LTP and enhancement of memory formation, and that defects caused by a genetic mutation can be ...

JCI online early table of contents: Nov. 6, 2008

... gene SLC36A2, which is normally responsible for making a transporter protein that helps kidney cells reabsorp protein building blocks. Furthermore, inheritance of one nonfunctional copy of SLC36A2 was the cause of HG. However, the genetic cause of these disorders was not quite that simple, as some ...

New candidate genes for schizophrenia identified

... biology of schizophrenia and explain why some individuals are at risk to develop the disease. "Another important step will be to assess the inheritance patterns of such CNVs," Ophoff said. "Since this is an inherited disease affecting approximately 1 percent of the population, this would be valuable ...

The first autism disease genes

... for a genetic predisposition to idiopathic autism. These data are interpreted as showing that liability to autism is in large part due to oligogenic inheritance in which a combination of multiple possibly interacting susceptibility alleles results in autism. A series of multiple independent whole genome ...

Highlights from the August 2008 issue of Ophthalmology

... to coping with poor distance vision, children with severe myopia are more prone to visual impairment and blindness later in life. Although genetic inheritance plays a role, the rapid rise of myopia suggests that environmental factors are driving the trend. Myopia usually begins and progresses during ...

JCI online early table of contents: July 1, 2008

... the baby does not suffer from the disease). Recent reports have suggested that less severe forms of the disease can arise in children through the inheritance of a mutated gene from only one parent (these mutations are said to be dominant as the mutated gene causes disease despite the presence of a normal ...

Gene sequence that can make half of us fatter is discovered

... of the genes behind problems such as diabetes and cardiovascular disease means that we will be in a good position to identify people whose genetic inheritance makes them most susceptible, added Professor Kooner. We cant change their genetic inheritance. But we can focus on preventative measures, including ...

Brain DNA 'remodeled' in alcoholism

... the Jesse Brown VA Medical Center in the April 2 issue of the Journal of Neuroscience. DNA can undergo changes in function without any changes in inheritance or coded sequence. These "epigenetic" changes are minor chemical modifications of chromatin -- dense bundles of DNA and proteins called histones. ...

PROGNOSIS Extends its Popular IP Telephony Management Software to Support Nortel Environments

... a multi-vendor deployment. "Many organizations are supporting multi-vendor IP-PBX systems to maintain vendor independence, or as a byproduct of the inheritance of legacy systems," said Mark Brayan, CEO of Integrated Research. "We have a management tool that gives a single, unified view across an ...

In silico modeling helps predict severity of mitochondrial disease

... cells will contain a mixture of mutant and normal mtDNA. The proportion of mutant mtDNA in most cases determines the severity of the disease. The inheritance of these diseases does not follow the rules of Mendelian genetics. Instead, there are large random shifts at the mtDNA mutation level between mother ...

Favrille to Report New Data on FavId (Now Specifid) at American Society of Hematology Annual Meeting

... The data suggest that long-term progression-free survival following a treatment regimen of Rituxan plus Specifid does not correlate with inheritance of particular Fc receptor polymorphisms nor with the production of anti-idiotypic antibody and therefore may rely more on a cell-mediated ...

Genetic differences point to ethnic and racial disparities in colorectal cancer risk

... study, a collaborative pooled analysis based at the University of Pittsburgh Medical Center and begun in 1997, they were able to look at genetic inheritance in different racial and ethnic groups. The investigators found that the odds of individuals developing colorectal cancer with two T genes versus two ...

Is there really a 'mommy' gene in women?

... and socio-cultural conditioning, as most analysts claim, or whether the choices that women are making about parenthood are influenced by genetic inheritance from maternal ancestors that were dominated by paternal ancestors. In a paper published in the current issue of Oikos an international journal ...

Experts propose cholesterol tests at 15 months of age

... routine vaccinations at about 15 months of age. Once an affected child is identified, their parents would then also be screened, since, given the inheritance of this disorder, for every affected child there would be one affected parent. Treatment to lower cholesterol could then be initiated immediately in ...

Discovery suggests location of genes for breast density, a strong risk factor for breast cancer

... 5p does not appear to affect breast density through its influence on BMI, she said. Only age, diagnosis of abnormal cells on a breast biopsy and inheritance of rare breast susceptibility genes, such as BRCA1 and BRCA2, are stronger risk predictors of breast cancer than is breast density, Vachon said. ...

Rare Mutation Causes Early Heart Disease and Metabolic Syndrome

... evidence of association of osteoporosis with CAD. By comparing the inheritance of CAD to the inheritance of each chromosome segment in the pedigree, the team narrowed the location ...

Genes responsible for cancer in women associated with increased cancer risk in men

... Looks like it is time men got their share from women in the inheritance of cancer as well. A genetic mutation linked with a greater risk of breast ... research. // Genetic mechanisms have been examined in the familial inheritance of breast cancer among women and the mutation in the BRCA2 gene is ...

Gene That Might Be Responsible For Aging

... was not different between fathers and sons and between spouses. Thus, the inheritance of a parental X chromosome (from mothers to sons and from both parents to ... say more research needs to be done on the newly discovered X-linked inheritance and the hypothesis that genetic predisposition to chronic age-related ...

Men and Women With Multiple Sclerosis Equally Transmit Genetic Risk to Kids

... study involved 16 times as many people as the previous published study. It casts further doubt on the widely believed multiple gene mode of inheritance of susceptibility to MS," said Ebers. The study is published June 27, 2007, in the online edition of Neurology. ...

Nepal Meet to Plan for Future of Children Affected by HIV

... policies in place, children vulnerable to or living with HIV face a bleak future: loss of their childhood and education, of family support and their inheritance and the likelihood of placement in orphanages and institutions - which should be the last resort." According to the consultative meet, which ...

Drink, Binge and the Genetic Link

... research is carried out to understand the underlying causes of all complex biological issues, including alcoholism . Unfolding the pattern of inheritance is the primary step towards understanding them. Alcoholism is the compulsive consumption of alcoholic beverages. This dependence on alcohol ...

Dystonia Awareness Week: 4 -11 June, 2007

... The answer is, in all probability, Yes! If it develops in childhood, it is probably due to affected genes inherited from parents. inheritance of generalized dystonia is due to the dominant nature of the gene(s) involved. This means, a parent affected with this type of dystonia has a 50% ...

Bill on HIV/AIDS Delayed Further

... would be taken up in the budget session. Now, the Health Minister is talking about further consultations. The bill also proposes protection of inheritance and property rights and recognises community-based alternatives to institutionalisation for vulnerable and affected children. ``Africa failed to ...

Gene Test to Spot Adults Who Might Get Diabetes

... international team of scientists has identified five different genetic variants that are linked to the condition, which is caused both by family inheritance and lifestyle factors such as poor diet, obesity and smoking. The five variants are thought together to account for about 70 per cent of the genetic ...

A Patented Device for Rapid Diagnosis of Diseases

... are of great importance, as they can provide genetic diagnosis tools for doctors to carry out early diagnoses of diseases associated with our genetic inheritance or with the malfunctioning of the mechanisms for the translation of our genetic code such as, possibly, the degenerative pathologies of Parkinsons ...

President Urges to Avoid Discrimination Against AIDS Patients

... the victims, women and children are the worst sufferers. They experience acute economic hardships, psychological distress, social ostracism, loss of inheritance and undergo severe physiological and social trauma. That being so, more focused attention need to be paid to women and children affected by AIDS. ...

A Novel Technique That Detects "Cancer Genes" From The Breath Of Smokers

... have identified four different factors they say predicts long-term survival in patients diagnosed with lung cancer, and one of the strongest is inheritance of a gene variant, GSTM1 positive, which is more efficient than another allele type of the GSTM1 gene at detoxifying carcinogens. They found that ...

Model Predicts Colon Cancer Inheritable Genetic Defects

... Department of Environmental Health Sciences. Lynch syndrome, also known as hereditary nonpolyposis colorectal cancer, is characterized by the inheritance of defects in the MLH1, MSH2 and MSH6 genes. These three genes help repair mismatches that can occur during the duplication of the genetic code when ...

Researchers Uncover Gene That Raises Risk for Type 1 Diabetes

... for Childhood Diabetes. “We found an extreme risk – greater than 80 percent – determined at birth by combining HLA-DR and HLA-DQ genetic typing with inheritance of other genes in the HLA region of chromosome 6. This research indicates an unexpected genetic determination of type 1 diabetes with a major unknown ...

New Study To Identify Osteoporosis Genes

... that people with a family history of osteoporosis are at increased risk of suffering from the condition themselves. This appears to be due to the inheritance of genes that predispose them to reduced bone mineral density. The people of Orkney have been specifically selected by the Edinburgh team ...
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