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Inflammatory in Medical News

Professor Bruce Beutler Joins aTyr Pharma's Scientific Advisory Board

... reduced suffering for millions of patients with inflammatory disease. Dr. Beutler is the inventor of ... inhibitors of TNF that are used to treat inflammatory diseases such as rheumatoid arthritis. ... proteins as biotherapeutics for treatment of inflammatory diseases as quickly as possible." ...

Study demonstrates the anti-inflammatory properties of pine bark extract

... occurring enzymes associated with a host of inflammatory conditions. "This study reveals that Pycnogenol can actually decrease pain and reduce inflammatory conditions, as has been previously reported, by ... for generating a repertoire of enzymes in inflammatory condition was tested by real-time PCR. The gene ...

Study Demonstrates the Anti-Inflammatory Properties of Pine Bark Extract on Inflammatory Mediators COX-2 and 5-LOX

... occurring enzymes associated with a host of inflammatory conditions. "This study reveals that Pycnogenol can actually decrease pain and reduce inflammatory conditions, as has been previously reported, by ... for generating a repertoire of enzymes in inflammatory condition was tested by real-time PCR. The gene ...

DNA-damaged cells communicate with neighbors to let them know they're in trouble

... signaling mechanism, which sets off an inflammatory response, explains how unsuccessful DNA repair at ... said Campisi. "With regard to aging, we think the inflammatory signals from damaged cells propagate an aging ... for the damaged cells to start secreting the inflammatory signals. "We think the cell is giving itself ...

ChemoCentryx to Present at The 9th World Congress on Inflammation in Tokyo, Japan

... Requirements and Efficacy of CCR9 Antagonism in inflammatory Bowel Disease" will be given on Thursday, July 9, ... in the search for innovative treatments in inflammatory disease," said Thomas J. Schall, Ph.D., ... and chemoattractant receptors in the treatment of inflammatory diseases." About ChemoCentryx ...

News briefs from the July issue of CHEST

... Research in Manhasset, NY, examined specific inflammatory biomarkers associated with cardiovascular disease ... are rapid consequences of smoking cessation on inflammatory biomarkers in women at risk for CVD. The article ... sputum, bronchoalveolar lavage (BAL), or mucosal inflammatory cell findings in adults or children. LABAs did ...

21st Century Obesity Pandemic Still Suffering From Effects of Tuberculosis Plague of the 1800s

... a link between tuberculosis and the metabolic and inflammatory processes that is tied to obesity. ... a link between tuberculosis and the metabolic and inflammatory processes that is tied to obesity. In an ... The result, he said, is an increase in inflammatory diseases such as diabetes, heart disease and ...

Video: New Biological Therapy Ilaris(R) Approved in US to Treat Children and Adults with CAPS, a Serious Life-Long Auto-Inflammatory Disease

... inflammation - Studies under way in other inflammatory disorders involving IL-1 beta, such as some forms ... FCAS, MWS and neonatal-onset multisystem inflammatory disease (NOMID). There are believed to be ... "Children and adults affected by these inflammatory diseases have to cope daily with distressing and ...

Phase 1 Study Initiated with Micromet Anti-GM-CS Human Antibody MT203

... play a significant role in various autoimmune and inflammatory diseases, including rheumatoid arthritis, ... development of MT203 in the field of severe inflammatory and autoimmune diseases." "We are very ... applications in the treatment of various inflammatory and autoimmune diseases, such as rheumatoid ...

'Life force' linked to body's ability to withstand stress

... Our ability to withstand stress-related, inflammatory diseases may be associated, not just with our ... may signal that blood levels of a key inflammatory molecule have crossed over a threshold linked to ... in life, have dramatically lower levels of the inflammatory chemical interleukin 6 (IL-6). Swiss psychiatrist ...

Structures from the human immune system's oldest branch shed light on a range of diseases

... insight into the pathogenesis of other immune and inflammatory diseases. The complement system, an ... C3 convertase, initiating a cascade of immune and inflammatory reactions. In order to avoid self-attack, ... of these and other diseases with immune or inflammatory components. Current work is focused on ...

Over half of people with rheumatoid arthritis have periodontitis

... arthritis (RA) also have periodontitis (a chronic inflammatory disease of the gum and surrounding ligaments and ... therapy may also be able to modulate the inflammatory process in the periodontium (the tissues ... disease and systemic conditions involving inflammatory rheumatic disease (especially RA), cardiovascular ...

Innovative New Wellness and Nutrition Program Leverages Latest Understanding of Relationship Between Diet and Genes

... health crisis, including obesity and chronic inflammatory disease. Shifting the paradigm to focus on ... pioneer in the study of gene-based nutrition and inflammatory diseases, as well as the launch of a ... numerous health issues, from obesity to chronic inflammatory diseases," said Dr. Chilton. "But through proven ...

Arete Therapeutics Presents Positive Clinical and Preclinical Data for AR9281

... molecule implicated in diabetes, hypertension and inflammatory disorders. Presented at the 69th Scientific ... reductions in plasma insulin, IL-6, an inflammatory molecule elevated in people with type 2 ... to treating type 2 diabetes, hypertension and inflammatory disease. The first two branches of this critical ...

Herb May Offer Hope for Autoimmune Diseases

... to treat because drugs that can suppress inflammatory attacks by the immune system on body tissues ... by T cells that regulate immune function and inflammatory responses. But the antibodies are expensive ... in a variety of autoimmune disorders, including inflammatory bowel disease, rheumatoid arthritis, multiple ...

Journal of Periodontology and the American Journal of Cardiology develop joint clinical recommendations

... deaths each day. Periodontal disease, a chronic inflammatory disease that destroys the bone and tissues that ... and unexplained elevation of hs-CRP or other inflammatory biomarkers. A periodontal evaluation of patients ... disease and explains the underlying biologic and inflammatory mechanisms that may be the basis for the ...

Healthy Gums and a Healthy Heart: The Perio-Cardio Connection

... deaths each day. Periodontal disease, a chronic inflammatory disease that destroys bone and gum tissues that ... disease and explains the underlying biologic and inflammatory mechanisms that may be the basis for the ... disease and cardiovascular disease are inflammatory diseases, and inflammation is the common ...

UCLA cancer researchers first to link intestinal inflammation with systemic chromosome damage

... the early identification and treatment of human inflammatory disorders, some of which increase risk for ... intestinal inflammation include Crohn's disease, inflammatory bowel disease, ulcerative colitis and Celiac ... and 2.2 million Europeans currently suffer from inflammatory bowel diseases and incidence worldwide is ...

The Pediatric IBD Center at Cedars-Sinai Medical Center Presents Rock-n-Reel 2009 Honoring Alexandra Milchan-Lambert & Scott Lambert

... LOS ANGELES, May 28 /PRNewswire/ -- The Pediatric inflammatory Bowel Disease (IBD) Center at Cedars-Sinai ... and authored book chapters for Trends in inflammatory Bowel Disease Therapy and inflammatory Bowel Disease: Diagnosis and Therapeutics as ...

The Gout & Uric Acid Education Society (GUAES) Announces New Survey Results Highlighting Major Gaps in Public Awareness of Gout

... In fact, gout is the most common form of inflammatory arthritis among adults. "There are a number ... forms of arthritis and the most common form of inflammatory arthritis among adults. Patients describe the ... . Please note that information on inflammatory arthritis, symptom management, and effects of ...

Cephalon Acquires Controlling Interest in Arana Therapeutics

... We look forward to advancing their pipeline in inflammatory diseases and cancer." The Offer will remain ... that will improve the lives of patients with inflammatory diseases and cancer. The company's lead ... alpha blocker in development for patients with inflammatory diseases. Arana has a strong patent portfolio ...

Trubion Pharmaceuticals, Inc. to Present Positive Data From a Phase 2b Re-treatment Study of TRU-015 at the 2009 EULAR Annual Meeting

... of TRU-015 for the treatment of autoimmune and inflammatory diseases, including RA. In the initial ... product candidates to treat autoimmune and inflammatory diseases and cancer. The Company's mission is to ... such as TRU-015 and SBI-087 for autoimmune and inflammatory diseases, developed under the company's Wyeth ...

Karolinska Institutet Awards Honorary Degree to Feinstein Institute CEO Kevin J. Tracey, MD

... medicines to treat chronic rheumatoid arthritis, inflammatory bowel disease and infection. He has made ... towards improving knowledge of regulating inflammatory processes. The Karolinska Institutet is ... disorders, rheumatoid arthritis, lupus, sepsis, inflammatory bowel disease, diabetes, human genetics, ...

Interleukin Genetics Reports First Quarter 2009 Financial Results

... D.C. The poster, titled "Identification of inflammatory Gene Variants as Biomarkers of Osteoporosis Risk ... Presented Data Highlighting Link Between inflammatory Genes and Weight Loss. In January, at a Keystone ... in the genes of interleukin-1 (IL-1) inflammatory pathway on dietary intervention induced weight ...

No longer afraid to be a bridesmaid or travel with the boss

... the treatments for ulcerative colitis, an inflammatory bowel disease, include a fistful of pills -- up ... "Managing stress is really important for managing inflammatory bowel disease," Keefer said. "We see young adults ... one of the few NIH-funded behavioral studies for inflammatory bowel disease, which affects between 250,000 to ...

Recent developments at Burnham Institute for Medical Research, May 2009

... leads for treating autoimmune diseases Several inflammatory diseases have been linked to a group of genes ... result is ameliorating various autoimmune and inflammatory diseases where hyperactivity of NLRs has been ... causes harm. One of the key mediators of the inflammatory response is the T-cell. The T-cell is activated ...

Equality of the sexes? Not always when it comes to biology

... could have a beneficial effect on the innate inflammatory response against bacterial pathogens. These ... enzyme called Caspase-12, which itself blocks the inflammatory process. The presence of estrogen would therefore ... demonstrate that women have a more powerful inflammatory response than men," said Dr. Saleh. This ...

Study in Nature Medicine establishes major new treatment target in diseased arteries

... triggering cells to self-destruct and promoting inflammatory cell signaling. Among the hormones best known ... decreases in ROS production, MMP activation and inflammatory cell influx compared to normal mice, with the ... production, CypA secretion, MMP activation and inflammatory cell recruitment in AAA. Also in the next phase, ...

PEAK Surgical Announces Positive Fascia Incision Healing Results From Preclinical Study of PEAK PlasmaBlade(TM) for Gynecologic Surgery

... injury depth, healed fascial scar width and inflammatory response with greater healed wound strength. ... control to evaluate for thermal injury depth, inflammatory response, collagen deposition and stage of ... The PlasmaBlade incisions demonstrated reduced inflammatory response at Week 1 compared with the scalpel ...

American Airlines Launches 2009 'Miles for the Cure' Campaign to Benefit Susan G. Komen for the Cure

... for the Cure's first Promise Grant, a study of inflammatory breast cancer (IBC) at The University of Texas ... aggressive form of breast cancer. It is called inflammatory breast cancer because its main symptoms are ... treatments for IBC. M.D. Anderson's Morgan Welch inflammatory Breast Cancer Clinic is the only facility of its ...

Drug May Help Against Inflammatory Breast Cancer

... drug lapatinib could be used to treat aggressive inflammatory breast cancer, suggest the findings of a phase 2 study. inflammatory breast cancer accounts for up to 6 percent of all ... HER2, a protein that's expressed much more in inflammatory breast cancer than in other, less aggressive ...

SIMPONI(TM) (golimumab) Receives FDA Approval as First Once-Monthly Anti-TNF for Treatment of Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis

... arthritis and ankylosing spondylitis are chronic inflammatory diseases that result in pain and inflammation, ... to the millions of patients living with chronic inflammatory diseases while expanding our immunology ... . Psoriatic arthritis is a chronic inflammatory disease that causes joint pain and swelling and ...

Even modest exercise can reduce negative effects of belly fat

... fat is particularly dangerous because it produces inflammatory molecules that enter the bloodstream and increase ... Obese people have higher levels of circulating inflammatory markers, such as C-reactive protein (CRP), which ... in belly fatthe type of fat that triggers these inflammatory diseases--was in the mice who were sedentary, ...

New oncogene gives valuable insight into hepatocellular tumors in humans

... of recurrent somatic mutation activating GP130 in inflammatory hepatocellular tumours reveals a new pathway of ... of hepatocellular tumors in humans. inflammatory hepatocellular adenomas (IHCA) are benign liver tumours defined by the presence of inflammatory infiltrates and by an over-expression ...

The Traveling Nut: Researchers From Around the World Explore the Impact of Almonds on the Body

... oxidative stress, blood sugar, insulin and inflammatory biomarkers. The 12-week clinical trial had ... LDL cholesterol, oxidative stress and inflammatory biomarkers. Results: Researchers found ... by 7.9%. Changes were also noted among the inflammatory biomarkers measured, as well as the resistance of ...

AAI honors Chen Dong for breakthrough T lymphocyte research

... added the vital color illustrating the roots of inflammatory diseases, such as asthma, and autoimmune ... of T helper cell 17 (Th17), its production of the inflammatory molecule interleukin-17 (IL-17), and their ... result. IL-17 was a suspect in autoimmune and inflammatory diseases, but its origins were unknown and ...

American Airlines Applauded for Its Fundraising to Support Susan G. Komen for the Cure(R), Promise Grant to The University of Texas M. D. Anderson Cancer Center

... Collaboration to Fight inflammatory Breast Cancer Already Making Gains in First Year ... D. Anderson Cancer Center for new treatments for inflammatory breast cancer (IBC). The airline has pledged $8 ... Promise Grant at M. D. Anderson's Morgan Welch inflammatory Breast Cancer Clinic, the only clinic of its kind ...

Biological FM signal maintains inflammation in cancer, asthma and other diseases

... a key player in conditions such as cancer, inflammatory bowel disease, rheumatoid arthritis and asthma ... to knock down one key biological player in an inflammatory disease. This research tells us that cells in inflammatory tissues may use very precise timing to ...

Cigarette smoke may alter immune response in COPD exacerbations

... whether and how cigarette smoke would change the inflammatory response to the bacteria that is the culprit ... and, notably, a shift in the expression of inflammatory markers. "Many interventions are developed ... in non-smokers. Smoking may change the underlying inflammatory pathways elicited after bacterial infection." ...

By shutting down inflammation, agent reverses damage from spinal cord injury in preclinical studies

... that an experimental agent is able to block this inflammatory reaction. "The findings we have made in this ... they can worsen the damage by releasing toxic inflammatory factors. "Under certain conditions, like ... months after an injury, the expression of certain inflammatory factors in the spinal cord is 4-5 times normal ...
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