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Hyperion Therapeutics Raises $60 Million Series C

... About Urea Cycle Disorders Urea cycle disorders are inherited, inborn errors of metabolism present in an estimated 1 in 10,000 births in the ... when administering to patients with hepatic or renal insufficiency or inborn errors of beta oxidation. The safety or efficacy of doses in excess of 20 ...

Hyperion Therapeutics Announces Results of Phase I Study in Patients With Liver Cirrhosis

... HE. About Urea Cycle Disorders Urea cycle disorders are inherited, inborn errors of metabolism present in an estimated 1 in 10,000 births in the ... when administering to patients with hepatic or renal insufficiency or inborn errors of beta oxidation. The safety or efficacy of doses in excess of 20 ...

BioMarin Announces Second Quarter 2009 Financial Results

... of 2010. Anticipated Upcoming Milestones 3Q09: Initiation of PEG-PAL Phase II trial 3Q09: International Congress of inborn Errors of Metabolism (ICIEM) meeting - Data on first cohort of patients from trial evaluating the impact of Kuvan on executive function ...

Hyperion Therapeutics Completes Phase 2 Data Analysis and Schedules End of Phase 2 Meeting With FDA for HPN-100 in the Chronic Treatment of Urea Cycle Disorders

... urea cycle disorders, hepatic encephalopathy, and other forms of hyperammonemia. About Urea Cycle Disorder Urea cycle disorders are inherited, inborn errors of metabolism present in an estimated 1 in 10,000 births in the United States. Patients with urea cycle disorders are deficient in one of the ...

Type 1 diabetes may result from good genes behaving badly

... not be due to bad genes but rather to good genes behaving badly. Because type 1 diabetes typically runs in families, scientists have looked for inborn genetic errors or gene variants passed on from generation to generation. Although this search has failed to find a single type 1 diabetes gene, many ...

Resveratrol: Thousands of Bottles of Wine, High-Dose Pills Not Required; Mega-doses May Induce Side Effects

... "rusting and calcifying" cells and tissues. Sardi says males universally age faster and have shorter life spans because they do not have inborn mechanisms to control the accumulation of iron and calcium as do menstruating females. By age 40 a male will have twice the iron and calcium load as ...

Drug therapy for PKU reverses heart damage

... chemicals, called oxygen free radicals. Doctors have used BH4 and diets that exclude phenylalanine for almost a decade to treat PKU, a so-called inborn error of metabolism that if left untreated causes irreversible brain damage. It affects an estimated 15,000 newborns in the United States each year. ...

Scans spot hidden tumors in rare cancer syndrome

... determine whether PET/CT screening is beneficial in LFS patients, who are highly susceptible to a variety of cancers from an early age because of an inborn gene mutation. We need to be cautious, and we shouldn't say that every patient with the syndrome should have a PET/CT examination," said Annick ...

Masimo SET Pulse Oximetry Technology Significantly Reduce the Risk of ROP

... state that the results were "significantly more favorable" for the center that switched to Masimo technology. "In a large group of examined inborn infants Joe E. Kiani, Chairman and CEO of Masimo stated; "In 2002, a group of researchers at Cedars Sinai led by Dr. Sola published a ...

Genetic Technology and Eugenics

... conceivable that we will begin to design our own evolutionary progress'. // ... ASIMOV The desire to strive towards betterment is an inborn human trait that has transformed man from a long-tailed, tree-swinging primate to a techno-savvy, go-getter. Although desire has been considered the ...

Breast Cancer Stem Cells Appear Resistant to Radiation Therapy

... which could titillate a signaling pathway, giving the message to stem cells, to reactivate and grow. Scientists opine that cells may comprise of an inborn radiation protectant, which is capable of offsetting radiation propelled DNA damage which is the reason behind the death of breast cancer cells. ...

Eighty Children Die Of Aids Due To Tainted Blood, Dirty Needles In Southern Kazakhstan

... //of a 5-year old boy in Sairam district – said the officials and non-governmental groups. It is believed that the five-year-old boy had a severe inborn cardiac defect, which caused the death. Chief physician of the regional HIV/ AIDS prevention and treatment center, Natalia Babina told the press ...

Gene Therapy Technique for Inherited Heart Problems in The Pipeline

... could be used in children,’ he said, adding that UF researchers hope to launch a trial in patients with Pompe disease early next year. ‘Many of the inborn errors have their most feared effects early in life, so we're pushing toward being able to do prevent disease as opposed to trying to correct later. ...

Are pretty faces associated with positive trait?

... thought to be intelligent and receive more attention in all walks of life. The inclination towards pretty faces is not very well understood but it is inborn and cross-cultural. Three experiments were done to analyze the liking for attractiveness. In the first study participants were asked to ...

Vitamin B12 Supplements Found To Improve Memory

... vitamins B12 and folate are risk factors for memory loss and Alzheimer's. However, they say this is the first study to look at the combined effect of inborn traits and environmental factors on memory. The predisposition to Alzheimer's is found in a version of the APOE gene. Fifteen percent of the ...
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